Research Topics
Species | A SagirSummaryAffiliation: Heinrich Heine University Country: Germany Publications
| Collaborators
|
Detail Information
Publications
SEN virus has an adverse effect on the survival of HIV-positive patientsAbdurrahman Sagir
Clinic for Gastroenterology, Hepatology and Infections bInstitute of Virology, University of Dusseldorf, Dusseldorf, Germany
AIDS 19:1091-6. 2005..Patients infected with HIV are often coinfected with other viruses...
SEN Virus infection in HIV/HCV coinfected patientsA Sagir
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Universitätsklinik Düsseldorf, Moorenstr 5, 40225 Dusseldorf, Germany
Eur J Med Res 13:495-9. 2008..The influence of SEN Virus (SENV) on the outcome of HCV therapy in HIV/HCV coinfected patients who underwent combination therapy with pegylated interferon (PEG-IFN) and ribavirin is unclear...
SEN virus does not affect treatment response in hepatitis C virus coinfected patients but SEN virus response depends on SEN virus DNA concentrationAbdurrahman Sagir
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Universitatsklinikum Dusseldorf, Moorenstrasse 5, 40225 Dusseldorf, Germany
World J Gastroenterol 10:1893-7. 2004..To clarify the effect of SEN virus (SENV) infection on a combination therapy including interferon alfa (IFN-alpha) or pegylated-IFN with ribavirin in patients with chronic hepatitis and the effect of a combination therapy on SENV...
Relapse to prior therapy is the most important factor for the retreatment response in patients with chronic hepatitis C virus infectionAbdurrahman Sagir
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Universitätsklinik Düsseldorf, Dusseldorf, Germany
Liver Int 27:954-9. 2007..In this report, we investigated response rates to combination therapy [standard IFN-alpha or PEG-IFN-alpha and ribavirin] in patients who relapsed or failed in prior therapy...
[Epidemiology of primary drug resistance in chronically HIV-infected patients in Nordrhein-Westfalen, Germany, 2001-2005]M Oette
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Universitatsklinikum Dusseldorf
Dtsch Med Wochenschr 132:977-82. 2007..Primary resistance is associated with reduced efficacy of antiretroviral therapy (ART). We determined the prevalence of primary resistance in Nordrhein-Westfalen, Germany...
Therapy outcome in patients with chronic hepatitis C: role of therapy supervision by expert hepatologistsA Sagir
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Universitätsklinik Düsseldorf, Moorenstr, Dusseldorf, Germany
J Viral Hepat 14:633-8. 2007..015). Patients with unfavourable genotypes 1 and 4 or with advanced liver damage benefit from HCV therapy supervision by a specialist, probably because of less frequent treatment interruptions or dose reductions...
Impact of rosiglitazone treatment on the bioavailability of antiretroviral compounds in HIV-positive patientsM Oette
Clinic for Gastroenterology, Hepatology, and Infectious Diseases, University Clinic Düsseldorf, Moorenstr 5, 40225 Dusseldorf
J Antimicrob Chemother 56:416-9. 2005..The insulin-sensitizer rosiglitazone is under investigation for therapy of HIV-associated lipodystrophy syndrome (LDS). Little is known about pharmacological interactions with antiretroviral (ARV) drugs...
Response to interferon alfa is hepatitis B virus genotype dependent: genotype A is more sensitive to interferon than genotype DA Erhardt
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Heinrich Heine Universitat Dusseldorf, Moorenstr 5, D 40225 Dusseldorf, Germany
Gut 54:1009-13. 2005..Current interferon alfa (IFN) treatment of chronic hepatitis B has limited efficacy. The role of hepatitis B virus (HBV) genotypes for response to IFN was investigated...
[Transient elastography for diagnosing liver cirrhosis]A Erhardt
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Heinrich Heine Universitat, Dusseldorf
Dtsch Med Wochenschr 131:2765-9. 2006..Detection of liver cirrhosis has numerous implications because of the potential sequelae of cirrhosis. Transient elastography (Fibroscan), was evaluated as a novel, non-invasive means of assessing cirrhosis by measuring liver stiffness...
Retrospective analysis of chronic hepatitis D in a West German University Clinic over two decades: migratory pattern, prevalence and clinical outcomeA Erhardt
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Universitätsklinikum der Heinrich Heine Universität Düsseldorf
Z Gastroenterol 48:813-7. 2010..Epidemiology, clinical features and long term-course of chronic hepatitis D were addressed in a non-endemic Central European area...
[Diagnosis of focal liver lesions in cirrhotic patients: comparison of contrast-enhanced ultrasound using sulphur hexafluoride (SF6) microbubbles and MRI using Gd-EOB-DTPA]D Blondin
Institut fur Radiologie, Heinrich Heine Universitat Dusseldorf
Z Gastroenterol 49:23-9. 2011..The diagnostic accuracies of contrast-enhanced sonography and hepatobiliary contrast-enhanced MRI of the liver in evaluating focal liver lesions in patients with liver cirrhosis were compared...
Successful treatment of hepatitis B virus associated polyarteritis nodosa with a combination of prednisolone, alpha-interferon and lamivudineA Erhardt
Klinik fur Gastroenterologie, Hepatologie und Infektologie, Heinrich Heine University, Dusseldorf Germany
J Hepatol 33:677-83. 2000..The present protocol of short-term prednisolone administration combined with alpha-interferon and lamivudine was effective for the treatment of HBV-related polyarteritis nodosa and may be a promising new therapeutic approach...
Trends of prevalence of primary HIV drug resistance in GermanyAbdurrahman Sagir
Clinic for Gastroenterology, Hepatology, and Infectious Diseases, University Clinic Düsseldorf, Moorenstrasse 5, 40225 Dusseldorf, Germany
J Antimicrob Chemother 60:843-8. 2007..Primary HIV drug resistance (PDR) is associated with poor treatment outcome of first-line highly active antiretroviral therapy (HAART). The aim of the study was to observe the trend of prevalence of PDR between 2001 and 2005...
Liver fibrosis in recessive multicystic kidney diseases: transient elastography for early detectionSebastian Kummer
Department of General Pediatrics, University Children s Hospital Düsseldorf, Dusseldorf, Germany
Pediatr Nephrol 26:725-31. 2011..This could facilitate diagnosis, monitoring, and management of liver involvement in ARPKD or any other cystic kidney disease...
Treatment of chronic hepatitis delta with pegylated interferon-alpha2bAndreas Erhardt
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Universitätsklinikum der Heinrich Heine Universität Düsseldorf, Dusseldorf, Germany
Liver Int 26:805-10. 2006..Chronic hepatitis D is difficult to treat. The present pilot study investigated the efficacy and tolerability of pegylated (PEG)-interferon (IFN)-alpha2b in chronic hepatitis D...
Predictors of short-term success of antiretroviral therapy in HIV infectionMark Oette
Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Clinic Düsseldorf Moorenstrasse 5, 40225 Dusseldorf, Germany
J Antimicrob Chemother 58:147-53. 2006..There is a lack of data presenting a combined assessment of a variety of these parameters for treatment efficacy in clinical routine practice...
SEN virus seroprevalence in HIV positive patients: association with immunosuppression and HIV-replicationAbdurrahman Sagir
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, der Universitätsklinik Düsseldorf, Moorenstr 5, 40225 Dusseldorf, Germany
J Clin Virol 33:183-7. 2005..The results were correlated with clinical markers such as HIV stage, CD4 cell count, HIV-RNA positivity, HAART or the transmission mode in HIV infected individuals...
Acute syphilitic blindness in an HIV-positive patientMark Oette
Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Clinic Düsseldorf, Germany
AIDS Patient Care STDS 19:209-11. 2005..Patients should receive treatment similar to that for neurosyphilis if there is suspicion of involvement of the central nervous system...
Is ultrasound a useful adjunct for assessing malaria patients?Joachim Richter
Tropical Medicine Unit, Clinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, 40225 Duesseldorf, Germany
Parasitol Res 94:349-53. 2004..26%; P<0.0421), the practical value of this finding is questionable. Ultrasonography cannot be regarded as a first-line diagnostic method in patients with malaria...
Lipodystrophy syndrome and self-assessment of well-being and physical appearance in HIV-positive patientsMark Oette
Clinic for Gastroenterology, Hepatology, and Infectious Diseases, Heinrich Heine University, Dusseldorf, Germany
AIDS Patient Care STDS 16:413-7. 2002..LDS may thus be perceived as a characteristic mark of being HIV-positive by affected persons. A stigmatizing effect and social disadvantages may be the consequences...
Atazanavir for treatment of HIV infection in clinical routine: efficacy, pharmacokinetics and safetyT Feldt
Clinic for Gastroenterology, Hepatology, and Infectious Diseases, , Moorenstr. 5, , Germany
Eur J Med Res 10:7-10. 2005..Drug levels were sufficient in the majority of cases. The variability of pharmacokinetic results in our sample supports therapeutic drug monitoring in patients treated with ATV...
SEN virus infectionAbdurrahman Sagir
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Universitätsklinik Düsseldorf, Moorenstr 5, 40225 Dusseldorf, Germany
Rev Med Virol 14:141-8. 2004..Data for other acute and chronic liver diseases are sparse. Further studies are needed to define the pathogenesis and clinical importance of SEN-V infection...
Cholestatic liver diseases from child to adult: the diversity of MDR3 diseaseR Kubitz
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Universitatsklinikum Dusseldorf
Z Gastroenterol 49:728-36. 2011..Even the same mutation may be associated with varying disease progression...
Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damageAbdurrahman Sagir
Klinik fur Gastroenterologie, Hepatologie und Infektiologie, Universitätsklinik Düsseldorf, Dusseldorf, Germany
Hepatology 47:592-5. 2008..CONCLUSION: Transient elastography frequently yields pathologically high values in patients with acute liver damage and is unsuitable for detecting cirrhosis/fibrosis in these patients...
Budesonide-induced acute hepatitis in an HIV-positive patient with ritonavir as a co-medicationAbdurrahman Sagir
AIDS 16:1191-2. 2002
Autoimmune thrombocytopenia induced by PEG-IFN-alpha2b plus ribavirin in hepatitis CAbdurrahman Sagir
Dig Dis Sci 47:562-3. 2002
