Frank Neumann

Summary

Affiliation: Heinrich Heine University
Country: Germany

Publications

  1. doi request reprint Therapy adapted to molecular response in patients with chronic myelogenous leukaemia in first chronic phase: results of the Duesseldorf study
    Frank Neumann
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Duesseldorf, Moorenstr Duesseldorf, Germany
    Hematol Oncol 26:213-8. 2008
  2. doi request reprint The sepsis-related Organ Failure Assessment (SOFA) score is predictive for survival of patients admitted to the intensive care unit following allogeneic blood stem cell transplantation
    Frank Neumann
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Duesseldorf, Duesseldorf, Germany
    Ann Hematol 87:299-304. 2008
  3. doi request reprint The role of natalizumab in hematopoietic stem cell mobilization
    Frank Neumann
    Heinrich Heine University, Department of Hematology, Oncology and Clinical Immunology, Duesseldorf, Germany
    Expert Opin Biol Ther 9:1099-106. 2009
  4. doi request reprint Levels of beta 2 microglobulin have a prognostic relevance for patients with myelodysplastic syndrome with regard to survival and the risk of transformation into acute myelogenous leukemia
    Frank Neumann
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Duesseldorf, Moorenstr 5, 40225 Duesseldorf, Germany
    Leuk Res 33:232-6. 2009
  5. ncbi request reprint A single dose of 6 or 12 mg of pegfilgrastim for peripheral blood progenitor cell mobilization results in similar yields of CD34+ progenitors in patients with multiple myeloma
    Ingmar Bruns
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University, Duesseldorf, Germany
    Transfusion 46:180-5. 2006
  6. ncbi request reprint Quantitative real-time reverse-transcription polymerase chain reaction for diagnosis of BCR-ABL positive leukemias and molecular monitoring following allogeneic stem cell transplantation
    Frank Neumann
    Department of Hematology, Oncology and Clinical Immunology, University of Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany
    Eur J Haematol 70:1-10. 2003
  7. ncbi request reprint Escalation therapy with bortezomib, dexamethasone and bendamustine for patients with relapsed or refractory multiple myeloma
    Roland Fenk
    Department of Haematology, Oncology and Clinical Immunology, Heinrich Heine University, Duesseldorf, Germany
    Leuk Lymphoma 48:2345-51. 2007
  8. ncbi request reprint Rituximab long-term maintenance therapy after autologous stem cell transplantation in patients with B-cell non-Hodgkin's lymphoma
    Frank Neumann
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University, Duesseldorf Moorenstr 5, 40225, Duesseldorf, Germany
    Ann Hematol 85:530-4. 2006
  9. doi request reprint Unrelated umbilical cord blood transplantation as salvage treatment for engraftment failure following autologous stem cell transplantation
    Roland Fenk
    Department of Haematology, Oncology and Clinical Immunology, Heinrich Heine University, Duesseldorf, Germany
    Leuk Res 32:1157-9. 2008
  10. ncbi request reprint Reliable engraftment, low toxicity, and durable remissions following allogeneic blood stem cell transplantation with minimal conditioning
    Guido Kobbe
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Exp Hematol 30:1346-53. 2002

Collaborators

Detail Information

Publications12

  1. doi request reprint Therapy adapted to molecular response in patients with chronic myelogenous leukaemia in first chronic phase: results of the Duesseldorf study
    Frank Neumann
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Duesseldorf, Moorenstr Duesseldorf, Germany
    Hematol Oncol 26:213-8. 2008
    ..In conclusion, the assessment of molecular response permits an individual patient-tailored treatment of CML in first chronic phase, resulting in the majority of patients achieving a major molecular response after 2 years of therapy...
  2. doi request reprint The sepsis-related Organ Failure Assessment (SOFA) score is predictive for survival of patients admitted to the intensive care unit following allogeneic blood stem cell transplantation
    Frank Neumann
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Duesseldorf, Duesseldorf, Germany
    Ann Hematol 87:299-304. 2008
    ..After univariate and multivariate analysis the SOFA score discriminated survivors and non-survivors of the ICU stay. We conclude that the SOFA score is predictive for survival when applied on the day of ICU admission...
  3. doi request reprint The role of natalizumab in hematopoietic stem cell mobilization
    Frank Neumann
    Heinrich Heine University, Department of Hematology, Oncology and Clinical Immunology, Duesseldorf, Germany
    Expert Opin Biol Ther 9:1099-106. 2009
    ..The use of natalizumab alone or in combination with either cytotoxic drugs or other antibodies might be a new modality for stem cell mobilization and a therapeutic option for patients with hematologic malignancies...
  4. doi request reprint Levels of beta 2 microglobulin have a prognostic relevance for patients with myelodysplastic syndrome with regard to survival and the risk of transformation into acute myelogenous leukemia
    Frank Neumann
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Duesseldorf, Moorenstr 5, 40225 Duesseldorf, Germany
    Leuk Res 33:232-6. 2009
    ..Using multivariate analysis we found the B2M level at the time of diagnosis to be an independent prognostic parameter for survival and for the risk of developing AML in high-risk MDS patients...
  5. ncbi request reprint A single dose of 6 or 12 mg of pegfilgrastim for peripheral blood progenitor cell mobilization results in similar yields of CD34+ progenitors in patients with multiple myeloma
    Ingmar Bruns
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University, Duesseldorf, Germany
    Transfusion 46:180-5. 2006
    ..Recently a polyethylene glycol-conjugated G-CSF (pegfilgrastim) was introduced that has a substantially longer t(1/2) than the original formula...
  6. ncbi request reprint Quantitative real-time reverse-transcription polymerase chain reaction for diagnosis of BCR-ABL positive leukemias and molecular monitoring following allogeneic stem cell transplantation
    Frank Neumann
    Department of Hematology, Oncology and Clinical Immunology, University of Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany
    Eur J Haematol 70:1-10. 2003
    ..In conclusion, the qPCR protocol used in this study is a reliable and fast method for monitoring molecular response in CML...
  7. ncbi request reprint Escalation therapy with bortezomib, dexamethasone and bendamustine for patients with relapsed or refractory multiple myeloma
    Roland Fenk
    Department of Haematology, Oncology and Clinical Immunology, Heinrich Heine University, Duesseldorf, Germany
    Leuk Lymphoma 48:2345-51. 2007
    ..In conclusion, this treatment algorithm resulted in responses in the majority of heavily pre-treated patients while at the same time restricting the toxicity of triple combination therapy to only 14% of non-responding patients...
  8. ncbi request reprint Rituximab long-term maintenance therapy after autologous stem cell transplantation in patients with B-cell non-Hodgkin's lymphoma
    Frank Neumann
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University, Duesseldorf Moorenstr 5, 40225, Duesseldorf, Germany
    Ann Hematol 85:530-4. 2006
    ..We conclude that a prolonged Rituximab maintenance therapy after PBSCT with monthly administration is reliable and safe...
  9. doi request reprint Unrelated umbilical cord blood transplantation as salvage treatment for engraftment failure following autologous stem cell transplantation
    Roland Fenk
    Department of Haematology, Oncology and Clinical Immunology, Heinrich Heine University, Duesseldorf, Germany
    Leuk Res 32:1157-9. 2008
    ..Moreover, the prompt availability allows transplantation to be performed at an optimal time...
  10. ncbi request reprint Reliable engraftment, low toxicity, and durable remissions following allogeneic blood stem cell transplantation with minimal conditioning
    Guido Kobbe
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Exp Hematol 30:1346-53. 2002
    ..To avoid high-dose conditioning and evaluate engraftment, toxicity, and GvT reactions, we treated a group of high-risk patients with a minimal intensive conditioning regimen followed by allogeneic BSCT...
  11. ncbi request reprint Distinct molecular phenotype of malignant CD34(+) hematopoietic stem and progenitor cells in chronic myelogenous leukemia
    Ralf Kronenwett
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Duesseldorf, Moorenstr 5, 40225 Duesseldorf, Germany
    Oncogene 24:5313-24. 2005
    ..05), suggesting that the adenosine A1 receptor is of functional relevance in CML hematopoietic progenitor cells...
  12. ncbi request reprint T and NK cells of B cell NHL patients exert cytotoxicity against lymphoma cells following binding of bispecific tetravalent antibody CD19 × CD3 or CD19 × CD16
    Lisa M Pörtner
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University, Dusseldorf, Germany
    Cancer Immunol Immunother 61:1869-75. 2012
    ..These results provide a rationale for the use of TandAbs for patients with B cell NHL, particularly in cases where remission with minimal residual disease could be achieved by cytotoxic chemotherapy...