T Menge

Summary

Affiliation: Heinrich Heine University
Country: Germany

Publications

  1. ncbi Relevant antibody subsets against MOG recognize conformational epitopes exclusively exposed in solid-phase ELISA
    Til Menge
    University of California San Francisco, Department of Neurology, San Francisco CA, USA
    Eur J Immunol 37:3229-39. 2007
  2. ncbi [Alemtuzumab: a further option for treatment of multiple sclerosis]
    T Menge
    Neurologische Klinik, Universitatsklinikum Dusseldorf, Moorenstr 5, 40225, Dusseldorf, Deutschland
    Nervenarzt 83:487-501. 2012
  3. ncbi Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis
    Til Menge
    Neuroimmunology Laboratories, Department of Neurology, University of California San Francisco, CA, USA
    J Neuroinflammation 8:161. 2011
  4. ncbi Acute disseminated encephalomyelitis: an acute hit against the brain
    Til Menge
    Department of Neurology, Heinrich Heine University of Dusseldorf, Germany
    Curr Opin Neurol 20:247-54. 2007
  5. ncbi Osteopontin: a novel axon-regulated Schwann cell gene
    Sebastian Jander
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    J Neurosci Res 67:156-66. 2002
  6. ncbi [Targeting B cells in multiple sclerosis. Current concepts and strategies]
    T Menge
    Neurologische Klinik, Heinrich Heine Universitat, Moorenstrasse 5, 40225, Dusseldorf, Deutschland
    Nervenarzt 80:190-8. 2009
  7. ncbi Disease-modifying agents for multiple sclerosis: recent advances and future prospects
    Til Menge
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Drugs 68:2445-68. 2008
  8. ncbi Inhibition of endogenous interferon beta by neutralizing antibodies against recombinant interferon beta
    Ajith Sominanda
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, Dusseldorf, Germany
    Arch Neurol 67:1095-101. 2010
  9. ncbi Acute disseminated encephalomyelitis: an update
    Til Menge
    Department of Neurology, University of San Francisco, San Francisco, Calif, USA
    Arch Neurol 62:1673-80. 2005
  10. ncbi Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis
    Patrice H Lalive
    Department of Neurology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 103:2280-5. 2006

Detail Information

Publications12

  1. ncbi Relevant antibody subsets against MOG recognize conformational epitopes exclusively exposed in solid-phase ELISA
    Til Menge
    University of California San Francisco, Department of Neurology, San Francisco CA, USA
    Eur J Immunol 37:3229-39. 2007
    ..Thus, the accurate detection of important subsets of pathogenic anti-MOG antibodies requires methods in which MOG is displayed similarly to its natural conformation in myelin...
  2. ncbi [Alemtuzumab: a further option for treatment of multiple sclerosis]
    T Menge
    Neurologische Klinik, Universitatsklinikum Dusseldorf, Moorenstr 5, 40225, Dusseldorf, Deutschland
    Nervenarzt 83:487-501. 2012
    ..This review summarizes the pre-clinical and clinical development of alemtuzumab and discusses potential modes of action as well as the pathogenetic link to the treatment emergent autoimmune phenomena...
  3. ncbi Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis
    Til Menge
    Neuroimmunology Laboratories, Department of Neurology, University of California San Francisco, CA, USA
    J Neuroinflammation 8:161. 2011
    ..Because epitope specificity may be a key factor determining anti-MOG reactivity we aimed at identifying a priori immunodominant MOG epitopes by monoclonal antibodies (mAbs) and at assessing clinical relevance of these epitopes in MS...
  4. ncbi Acute disseminated encephalomyelitis: an acute hit against the brain
    Til Menge
    Department of Neurology, Heinrich Heine University of Dusseldorf, Germany
    Curr Opin Neurol 20:247-54. 2007
    ..ADEM is a para- or postinfectious autoimmune demyelinating disease of the central nervous system and has been considered a monophasic disease. The highest incidence of ADEM is observed during childhood...
  5. ncbi Osteopontin: a novel axon-regulated Schwann cell gene
    Sebastian Jander
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    J Neurosci Res 67:156-66. 2002
    ..The lack of OPN induction in infiltrating macrophages indicates fundamental differences in tissue repair between axonal injury in the peripheral nervous system and structural lesions in other organ systems...
  6. ncbi [Targeting B cells in multiple sclerosis. Current concepts and strategies]
    T Menge
    Neurologische Klinik, Heinrich Heine Universitat, Moorenstrasse 5, 40225, Dusseldorf, Deutschland
    Nervenarzt 80:190-8. 2009
    ..This review discusses the role of autoreactive B cells in the context of MS, analyzes the B-cell-depleting treatment studies reported, and provides information on planned and future B-cell-directed therapeutic strategies in MS...
  7. ncbi Disease-modifying agents for multiple sclerosis: recent advances and future prospects
    Til Menge
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Drugs 68:2445-68. 2008
    ..Finally, with the advent of these highly potent novel therapies, rare, but potentially serious adverse effects have been noted, namely infections and malignancies. These are critically reviewed and put into perspective...
  8. ncbi Inhibition of endogenous interferon beta by neutralizing antibodies against recombinant interferon beta
    Ajith Sominanda
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, Dusseldorf, Germany
    Arch Neurol 67:1095-101. 2010
    ....
  9. ncbi Acute disseminated encephalomyelitis: an update
    Til Menge
    Department of Neurology, University of San Francisco, San Francisco, Calif, USA
    Arch Neurol 62:1673-80. 2005
    ....
  10. ncbi Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis
    Patrice H Lalive
    Department of Neurology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 103:2280-5. 2006
    ....
  11. ncbi Antibody responses against galactocerebroside are potential stage-specific biomarkers in multiple sclerosis
    Til Menge
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143-0114, USA
    J Allergy Clin Immunol 116:453-9. 2005
    ..This novel assay is a suitable and valuable method to increase accuracy of diagnosis and disease staging in MS...
  12. ncbi Pharmacological treatment of early multiple sclerosis
    Olaf Stuve
    Neurology Section, VA North Texas Health Care System, Medical Service, Dallas, Texas 75216, USA
    Drugs 68:73-83. 2008
    ....