T Meissner

Summary

Affiliation: Heinrich Heine University
Country: Germany

Publications

  1. doi request reprint Richner-Hanhart syndrome detected by expanded newborn screening
    Thomas Meissner
    Department of General Pediatrics, University Children s Hospital Düsseldorf, Dusseldorf, Germany
    Pediatr Dermatol 25:378-80. 2008
  2. doi request reprint Carbohydrate intake in relation to BMI, HbA1c and lipid profile in children and adolescents with type 1 diabetes
    Thomas Meissner
    Department of General Paediatrics, Neonatology and Paediatric Cardiology, University Children s Hospital Düsseldorf, Moorenstr 5, 40225 Duesseldorf, Germany Electronic address
    Clin Nutr 33:75-8. 2014
  3. pmc Propionic acidemia: clinical course and outcome in 55 pediatric and adolescent patients
    Sarah C Grünert
    Labor für Klinische Biochemie und Stoffwechsel, Zentrum für Kinder und Jugendmedizin, Universitatsklinikum Freiburg, Freiburg, Germany
    Orphanet J Rare Dis 8:6. 2013
  4. doi request reprint Diagnostic difficulties in glucokinase hyperinsulinism
    T Meissner
    Department of General Pediatrics, University Children s Hospital, Dusseldorf, Germany
    Horm Metab Res 41:320-6. 2009
  5. ncbi request reprint Massive insulin secretion in response to anaerobic exercise in exercise-induced hyperinsulinism
    T Meissner
    Department of General Pediatrics, University Children s Hospital, Dusseldorf, Germany
    Horm Metab Res 37:690-4. 2005
  6. ncbi request reprint Odd-numbered long-chain fatty acids in erythrocyte phospholipids as long-term follow-up parameter in propionic acidemia
    Thomas Meissner
    Department of General Pediatrics, University Children s Hospital, Dusseldorf, Germany
    Clin Chem Lab Med 42:1005-8. 2004
  7. ncbi request reprint Novel missense mutations outside the allosteric domain of glutamate dehydrogenase are prevalent in European patients with the congenital hyperinsulinism-hyperammonemia syndrome
    R Santer
    Department of Pediatrics, University Children s Hospital, Kiel, Germany
    Hum Genet 108:66-71. 2001
  8. ncbi request reprint Congenital hyperinsulinism: molecular basis of a heterogeneous disease
    T Meissner
    Division of Metabolic Diseases, University Children s Hospital, Heidelberg, Germany
    Hum Mutat 13:351-61. 1999
  9. doi request reprint Association of exercise-induced hyperinsulinaemic hypoglycaemia with MCT1-expressing insulinoma
    J Marquard
    Department of General Paediatrics, Neonatology and Paediatric Cardiology, University Children s Hospital Düsseldorf, Moorenstrasse 5, 40225 Dusseldorf, Germany
    Diabetologia 56:31-5. 2013
  10. ncbi request reprint Acute metabolic crisis with extreme deficiency of glutathione in combination with decreased levels of leukotriene C4 in a patient with glutathione synthetase deficiency
    E Mayatepek
    Department of General Pediatrics, University Children s Hospital, Dusseldorf, Germany
    J Inherit Metab Dis 27:297-9. 2004

Collaborators

Detail Information

Publications23

  1. doi request reprint Richner-Hanhart syndrome detected by expanded newborn screening
    Thomas Meissner
    Department of General Pediatrics, University Children s Hospital Düsseldorf, Dusseldorf, Germany
    Pediatr Dermatol 25:378-80. 2008
    ..This demonstrates that early diagnosis of Richner-Hanhart syndrome is possible in neonates by extended newborn screening. Early introduction of dietary treatment is a prerequisite to reduce the risk of clinical symptoms...
  2. doi request reprint Carbohydrate intake in relation to BMI, HbA1c and lipid profile in children and adolescents with type 1 diabetes
    Thomas Meissner
    Department of General Paediatrics, Neonatology and Paediatric Cardiology, University Children s Hospital Düsseldorf, Moorenstr 5, 40225 Duesseldorf, Germany Electronic address
    Clin Nutr 33:75-8. 2014
    ..To compare reported and recommended carbohydrate intake in children and adolescents with type 1 diabetes (T1D) and to explore associations with BMI, HbA1c and lipid profile...
  3. pmc Propionic acidemia: clinical course and outcome in 55 pediatric and adolescent patients
    Sarah C Grünert
    Labor für Klinische Biochemie und Stoffwechsel, Zentrum für Kinder und Jugendmedizin, Universitatsklinikum Freiburg, Freiburg, Germany
    Orphanet J Rare Dis 8:6. 2013
    ..Propionic acidemia is an inherited disorder caused by deficiency of propionyl-CoA carboxylase. Although it is one of the most frequent organic acidurias, information on the outcome of affected individuals is still limited...
  4. doi request reprint Diagnostic difficulties in glucokinase hyperinsulinism
    T Meissner
    Department of General Pediatrics, University Children s Hospital, Dusseldorf, Germany
    Horm Metab Res 41:320-6. 2009
    ..Delay of diagnosis might result in mental handicap of the affected individuals...
  5. ncbi request reprint Massive insulin secretion in response to anaerobic exercise in exercise-induced hyperinsulinism
    T Meissner
    Department of General Pediatrics, University Children s Hospital, Dusseldorf, Germany
    Horm Metab Res 37:690-4. 2005
    ....
  6. ncbi request reprint Odd-numbered long-chain fatty acids in erythrocyte phospholipids as long-term follow-up parameter in propionic acidemia
    Thomas Meissner
    Department of General Pediatrics, University Children s Hospital, Dusseldorf, Germany
    Clin Chem Lab Med 42:1005-8. 2004
    ....
  7. ncbi request reprint Novel missense mutations outside the allosteric domain of glutamate dehydrogenase are prevalent in European patients with the congenital hyperinsulinism-hyperammonemia syndrome
    R Santer
    Department of Pediatrics, University Children s Hospital, Kiel, Germany
    Hum Genet 108:66-71. 2001
    ....
  8. ncbi request reprint Congenital hyperinsulinism: molecular basis of a heterogeneous disease
    T Meissner
    Division of Metabolic Diseases, University Children s Hospital, Heidelberg, Germany
    Hum Mutat 13:351-61. 1999
    ..The heterogeneous group of patients with CHI may now be classified according to their basic defects in the four different genes, with potential implications for a more specific treatment...
  9. doi request reprint Association of exercise-induced hyperinsulinaemic hypoglycaemia with MCT1-expressing insulinoma
    J Marquard
    Department of General Paediatrics, Neonatology and Paediatric Cardiology, University Children s Hospital Düsseldorf, Moorenstrasse 5, 40225 Dusseldorf, Germany
    Diabetologia 56:31-5. 2013
    ..Recently, transgenic Mct1 expression in pancreatic beta cells was shown to introduce EIHI symptoms in mice. To date, MCT1 has not been demonstrated in insulin-producing cells from an EIHI patient...
  10. ncbi request reprint Acute metabolic crisis with extreme deficiency of glutathione in combination with decreased levels of leukotriene C4 in a patient with glutathione synthetase deficiency
    E Mayatepek
    Department of General Pediatrics, University Children s Hospital, Dusseldorf, Germany
    J Inherit Metab Dis 27:297-9. 2004
    ..The highly disturbed glutathione synthesis is postulated to be the reason for a deficient synthesis of cysteinyl leukotrienes, which may at least in part be responsible for the severe clinical symptoms...
  11. doi request reprint Bloody nipple discharge (BND) in an 8 months old girl and a 9 months old male--rational diagnostic approach
    S Harmsen
    Klinik fur Allgemeine Padiatrie, Zentrum für Kinder und Jugendmedizin, Universitatsklinikum Dusseldorf, Moorenstrasse 5, Dusseldorf, Germany
    Klin Padiatr 222:79-83. 2010
    ..Here we discuss a rational diagnostic approach on the basis of 2 patients with bloody nipple discharge at the age of 8 and 9 months which resolved spontaneously without treatment after 3 and 6 months, respectively...
  12. ncbi request reprint Identification of the peroxisomal beta-oxidation enzymes involved in the degradation of leukotrienes
    Sacha Ferdinandusse
    Department of Clinical Chemistry, Emma Children s Hospital, Academic Medical Center, University of Amsterdam, P O Box 22700, 1105 AZ Amsterdam, The Netherlands
    Biochem Biophys Res Commun 293:269-73. 2002
    ....
  13. ncbi request reprint Physical exercise-induced hyperinsulinemic hypoglycemia is an autosomal-dominant trait characterized by abnormal pyruvate-induced insulin release
    Timo Otonkoski
    Program for Developmental and Reproductive Biology, Biomedicum, Helsinki, Finland
    Diabetes 52:199-204. 2003
    ..In conclusion, EIHI represents a new autosomal-dominant hyperinsulinemia syndrome that may be more common than has been realized. The pyruvate test provides a simple, safe, and specific diagnostic test for this condition...
  14. ncbi request reprint Synthesis and metabolism of leukotrienes in gamma-glutamyl transpeptidase deficiency
    Ertan Mayatepek
    Department of General Pediatrics, University Children s Hospital, Dusseldorf, Germany
    J Lipid Res 45:900-4. 2004
    ..GGT deficiency represents a new inborn error of cysteinyl LT synthesis and provides a unique model in which to study the pathobiological coherence of LT and glutathione metabolism...
  15. ncbi request reprint Role of leukotrienes as indicators of the inflammatory demyelinating reaction in x-linked cerebral adrenoleukodystrophy
    Ertan Mayatepek
    J Neurol 250:1259-60. 2003
  16. ncbi request reprint Analysis of cysteinyl leukotrienes and their metabolites in bile of patients with peroxisomal or mitochondrial beta-oxidation defects
    Ertan Mayatepek
    Department of General Pediatrics, University Children s Hospital, Moorenstrasse 5, D 40225, Dusseldorf, Germany
    Clin Chim Acta 345:89-92. 2004
    ..g. contributing to liver injury. In addition, our data confirm that the beta-oxidation of cysteinyl LTs in vivo occurs in peroxisomes and not in mitochondria...
  17. ncbi request reprint Decline of acute encephalopathic crises in children with glutaryl-CoA dehydrogenase deficiency identified by newborn screening in Germany
    Stefan Kölker
    Department of General Pediatrics, Division of Inborn Metabolic Diseases, University Children s Hospital Heidelberg, D 69120 Heidelberg, Germany
    Pediatr Res 62:357-63. 2007
    ..No patient was known to be missed by newborn screening from 1999 to 2005. In conclusion, this study confirms that newborn screening for GCDH deficiency in combination with intensive management is beneficial...
  18. ncbi request reprint [Diabetes: education more effective than drugs? Those who know more, live longer]
    Thomas Meissner
    MMW Fortschr Med 145:14. 2003
  19. doi request reprint Congenital central hypoventilation syndrome with hyperinsulinism in a preterm infant
    Ulrike Hennewig
    Department of General Pediatrics, University Hospital Duesseldorf, Duesseldorf, Germany
    J Hum Genet 53:573-7. 2008
    ..Based on the observation of three patients presenting with the combination of congenital hyperinsulinism and CCHS, hyperinsulinism might represent an additional clinical feature of CCHS...
  20. ncbi request reprint Long-term follow-up of 114 patients with congenital hyperinsulinism
    Thomas Meissner
    Clinic of General Pediatrics, University Children s Hospital, Dusseldorf, Germany
    Eur J Endocrinol 149:43-51. 2003
    ..The term congenital hyperinsulinism (CHI) comprises a group of different genetic disorders with the common finding of recurrent episodes of hyperinsulinemic hypoglycemia...
  21. ncbi request reprint Urinary alpha-ketoglutarate is elevated in patients with hyperinsulinism-hyperammonemia syndrome
    Thomas Meissner
    Department of General Pediatrics, University Children s Hospital, Moorenstr 5, D 40225 Dusseldorf, Germany
    Clin Chim Acta 341:23-6. 2004
    ..Therefore, we investigated whether urinary concentration of alpha-ketoglutarate (alpha-KG) is elevated in patients with hyperinsulinism...
  22. ncbi request reprint Clinical and genetic heterogeneity in congenital hyperinsulinism
    Thomas Meissner
    Division of Metabolic and Endocrine Diseases, University Children s Hospital, Heidelberg, Germany
    Eur J Pediatr 161:6-20. 2002
    ..Application of these aspects to general clinical practice will lead to an improvement of the management and long-term outcome of affected patients...
  23. pmc Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells
    Timo Otonkoski
    Hospital for Children and Adolescents and Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
    Am J Hum Genet 81:467-74. 2007
    ..These findings describe a novel disease mechanism based on the failure of cell-specific transcriptional silencing of a gene that is highly expressed in other tissues...