W Martin

Summary

Affiliation: Heinrich Heine University
Country: Germany

Publications

  1. doi request reprint Hydrothermal vents and the origin of life
    William Martin
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, 40225 Dusseldorf, Germany
    Nat Rev Microbiol 6:805-14. 2008
  2. pmc Ancestral genome sizes specify the minimum rate of lateral gene transfer during prokaryote evolution
    Tal Dagan
    Institut für Botanik III, Heinrich Heine Universitat, Universitatsstrasse 1, 40225 Dusseldorf, Germany
    Proc Natl Acad Sci U S A 104:870-5. 2007
  3. pmc The origin of mitochondria in light of a fluid prokaryotic chromosome model
    Christian Esser
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Universitatsstr 1, 40225 Dusseldorf, Germany
    Biol Lett 3:180-4. 2007
  4. doi request reprint A machine-learning approach reveals that alignment properties alone can accurately predict inference of lateral gene transfer from discordant phylogenies
    Mayo Roettger
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Germany
    Mol Biol Evol 26:1931-9. 2009
  5. pmc Prokaryotic evolution and the tree of life are two different things
    Eric Bapteste
    UPMC, UMR CNRS 7138, 75005 Paris, France
    Biol Direct 4:34. 2009
  6. pmc Evolution of spliceosomal introns following endosymbiotic gene transfer
    Nahal Ahmadinejad
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
    BMC Evol Biol 10:57. 2010
  7. pmc Anaerobic animals from an ancient, anoxic ecological niche
    Marek Mentel
    Department of Biochemistry, Faculty of Natural Sciences, Comenius University, Mlynska dolina CH 1, Bratislava, Slovakia
    BMC Biol 8:32. 2010
  8. pmc Secondary loss of chloroplasts in trypanosomes
    William Martin
    Institute of Botany III, Universitat Dusseldorf, Universitatstrasse 1, D 40225 Dusseldorf, Germany
    Proc Natl Acad Sci U S A 100:765-7. 2003
  9. pmc Evolutionary origins of metabolic compartmentalization in eukaryotes
    William Martin
    Institute of Botany III, University of Dusseldorf, Universitatsstr 1, 40225 Dusseldorf, Germany
    Philos Trans R Soc Lond B Biol Sci 365:847-55. 2010
  10. ncbi request reprint Early cell evolution, eukaryotes, anoxia, sulfide, oxygen, fungi first (?), and a tree of genomes revisited
    William Martin
    Institute of Botany III, University of Dusseldorf, Universitatsstr 1, D 40225 Düsseldorf Germany
    IUBMB Life 55:193-204. 2003

Collaborators

Detail Information

Publications78

  1. doi request reprint Hydrothermal vents and the origin of life
    William Martin
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, 40225 Dusseldorf, Germany
    Nat Rev Microbiol 6:805-14. 2008
    ..Hydrothermal vents thus unite microbiology and geology to breathe new life into research into one of biology's most important questions - what is the origin of life?..
  2. pmc Ancestral genome sizes specify the minimum rate of lateral gene transfer during prokaryote evolution
    Tal Dagan
    Institut für Botanik III, Heinrich Heine Universitat, Universitatsstrasse 1, 40225 Dusseldorf, Germany
    Proc Natl Acad Sci U S A 104:870-5. 2007
    ..1 LGT events per gene family and gene family lifespan and this minimum rate increases sharply when genes present in only a few genomes are excluded from the analysis...
  3. pmc The origin of mitochondria in light of a fluid prokaryotic chromosome model
    Christian Esser
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Universitatsstr 1, 40225 Dusseldorf, Germany
    Biol Lett 3:180-4. 2007
    ..Our findings bear upon attempts to reconstruct the mitochondrial ancestor and upon inferences concerning the collection of genes that the mitochondrial ancestor possessed at the time that it became an endosymbiont...
  4. doi request reprint A machine-learning approach reveals that alignment properties alone can accurately predict inference of lateral gene transfer from discordant phylogenies
    Mayo Roettger
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Germany
    Mol Biol Evol 26:1931-9. 2009
    ..Using a support vector machine, we were able to predict the inference of discordant tree topologies with up to 80% accuracy from alignment properties alone...
  5. pmc Prokaryotic evolution and the tree of life are two different things
    Eric Bapteste
    UPMC, UMR CNRS 7138, 75005 Paris, France
    Biol Direct 4:34. 2009
    ..In the following we will consider this circumstance from philosophical, scientific, and epistemological perspectives, surmising that phylogeny opted for a single model as a holdover from the Modern Synthesis of evolution...
  6. pmc Evolution of spliceosomal introns following endosymbiotic gene transfer
    Nahal Ahmadinejad
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
    BMC Evol Biol 10:57. 2010
    ..We circumvent this problem by using genes originated by endosymbiotic gene transfer, in which an intron-less structure at the time of the transfer can be assumed...
  7. pmc Anaerobic animals from an ancient, anoxic ecological niche
    Marek Mentel
    Department of Biochemistry, Faculty of Natural Sciences, Comenius University, Mlynska dolina CH 1, Bratislava, Slovakia
    BMC Biol 8:32. 2010
    ..They also testify that a fuller understanding of eukaryotic and metazoan evolution will come from the study of modern anoxic and hypoxic habitats...
  8. pmc Secondary loss of chloroplasts in trypanosomes
    William Martin
    Institute of Botany III, Universitat Dusseldorf, Universitatstrasse 1, D 40225 Dusseldorf, Germany
    Proc Natl Acad Sci U S A 100:765-7. 2003
  9. pmc Evolutionary origins of metabolic compartmentalization in eukaryotes
    William Martin
    Institute of Botany III, University of Dusseldorf, Universitatsstr 1, 40225 Dusseldorf, Germany
    Philos Trans R Soc Lond B Biol Sci 365:847-55. 2010
    ..Dual-targeting of proteins is indeed very common within eukaryotic cells, suggesting that targeting variation required for this minor mistargeting mechanism to operate exists in nature...
  10. ncbi request reprint Early cell evolution, eukaryotes, anoxia, sulfide, oxygen, fungi first (?), and a tree of genomes revisited
    William Martin
    Institute of Botany III, University of Dusseldorf, Universitatsstr 1, D 40225 Düsseldorf Germany
    IUBMB Life 55:193-204. 2003
    ..Because of lateral gene transfer and endosymbiosis, branches in the tree of genomes intermingle and occasionally fuse, but the overall contours of cell history nonetheless seem sketchable and roughly correlateable with geological time...
  11. pmc Gene transfer from organelles to the nucleus: frequent and in big chunks
    William Martin
    Institute of Botany III, Universitat Dusseldorf, Universitatstrasse 1, D 40225 Dusseldorf, Germany
    Proc Natl Acad Sci U S A 100:8612-4. 2003
  12. pmc On the origins of cells: a hypothesis for the evolutionary transitions from abiotic geochemistry to chemoautotrophic prokaryotes, and from prokaryotes to nucleated cells
    William Martin
    Institut für Botanik III, Heinrich Heine Universitaet Düsseldorf, Universitatsstrasse 1, 40225 Dusseldorf, Germany
    Philos Trans R Soc Lond B Biol Sci 358:59-83; discussion 83-5. 2003
    ..Under these premises, the most ancient divide in the living world is that between eubacteria and archaebacteria, yet the steepest evolutionary grade is that between prokaryotes and eukaryotes...
  13. ncbi request reprint Chloroplast genome phylogenetics: why we need independent approaches to plant molecular evolution
    William Martin
    Institute of Botany III, University of Dusseldorf, Universitatsstr 1, 40225 Dusseldorf, Germany
    Trends Plant Sci 10:203-9. 2005
    ....
  14. pmc Evolutionary analysis of Arabidopsis, cyanobacterial, and chloroplast genomes reveals plastid phylogeny and thousands of cyanobacterial genes in the nucleus
    William Martin
    Institut fur Botanik, Heinrich Heine Universitat, Universitatsstrasse 1, 40225 Dusseldorf, Germany
    Proc Natl Acad Sci U S A 99:12246-51. 2002
    ....
  15. ncbi request reprint A reality check for alignments and trees
    William Martin
    Institute of Botany III, University of Dusseldorf, Dusseldorf, Germany
    Trends Genet 23:478-80. 2007
    ..The new findings highlight sequence alignment as a crucial step in molecular evolutionary studies and provide straightforward measures to assess alignment reliability...
  16. ncbi request reprint Introns and the origin of nucleus-cytosol compartmentalization
    William Martin
    Institute of Botany III, University of Dusseldorf, D 40225 Dusseldorf, Germany
    Nature 440:41-5. 2006
    ..The rapid, fortuitous spread of introns following the origin of mitochondria is adduced as the selective pressure that forged nucleus-cytosol compartmentalization...
  17. ncbi request reprint The missing link between hydrogenosomes and mitochondria
    William Martin
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Universitatsstrasse 1, 40225 Dusseldorf, Germany
    Trends Microbiol 13:457-9. 2005
    ..The new findings are a benchmark for our understanding of hydrogenosome origins...
  18. pmc Early evolution without a tree of life
    William F Martin
    Institut of Botany III, University of Dusseldorf, 40225 Dusseldorf, Germany
    Biol Direct 6:36. 2011
    ..Microbial genome evolution is not a treelike process because of lateral gene transfer and the endosymbiotic origins of organelles. The lack of true intermediates in the prokaryote-to-eukaryote transition has a bioenergetic cause...
  19. ncbi request reprint Mitochondrial trans-2-enoyl-CoA reductase of wax ester fermentation from Euglena gracilis defines a new family of enzymes involved in lipid synthesis
    Meike Hoffmeister
    Institute of Botany III, University of Dusseldorf, D 40225 Dusseldorf, Germany
    J Biol Chem 280:4329-38. 2005
    ..Trans-2-enoyl-CoA reductase assigns a biochemical activity, NAD(P)H-dependent acyl-CoA synthesis from enoyl-CoA, to one member of this gene family of previously unknown function...
  20. ncbi request reprint A genome phylogeny for mitochondria among alpha-proteobacteria and a predominantly eubacterial ancestry of yeast nuclear genes
    Christian Esser
    Institute of Botany III, University of Dusseldorf, Dusseldorf, Germany
    Mol Biol Evol 21:1643-60. 2004
    ..Among eubacteria and archaebacteria, proteobacterial and methanogen genomes, respectively, shared more similarity with the yeast genome than other prokaryotic genomes surveyed...
  21. ncbi request reprint Chloroplast phosphoglycerate kinase from Euglena gracilis: endosymbiotic gene replacement going against the tide
    Ulrich Nowitzki
    Institute of Botany III, Heinrich Heine University Dusseldorf, Germany
    Eur J Biochem 271:4123-31. 2004
    ..The chloroplast isoenzyme of E. gracilis did not show a close relationship to sequences from other photosynthetic organisms but was most closely related to cytosolic homologues from animals and fungi...
  22. ncbi request reprint Euglena gracilis rhodoquinone:ubiquinone ratio and mitochondrial proteome differ under aerobic and anaerobic conditions
    Meike Hoffmeister
    Institute of Botany III, University of Dusseldorf, D 40225 Dusseldorf, Germany
    J Biol Chem 279:22422-9. 2004
    ....
  23. doi request reprint Genes of cyanobacterial origin in plant nuclear genomes point to a heterocyst-forming plastid ancestor
    Oliver Deusch
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Universitatsstrasse 1, Dusseldorf, Germany
    Mol Biol Evol 25:748-61. 2008
    ....
  24. ncbi request reprint Supertrees and symbiosis in eukaryote genome evolution
    Christian Esser
    Institute of Botany III, University of Dusseldorf, D 40225 Dusseldorf, Germany
    Trends Microbiol 15:435-7. 2007
    ....
  25. ncbi request reprint Single eubacterial origin of eukaryotic sulfide:quinone oxidoreductase, a mitochondrial enzyme conserved from the early evolution of eukaryotes during anoxic and sulfidic times
    Ursula Theissen
    Institute of Botany III, University of Dusseldorf, Dusseldorf, Germany
    Mol Biol Evol 20:1564-74. 2003
    ....
  26. pmc Energy metabolism among eukaryotic anaerobes in light of Proterozoic ocean chemistry
    Marek Mentel
    Institute of Botany, University of Dusseldorf, Dusseldorf, Germany
    Philos Trans R Soc Lond B Biol Sci 363:2717-29. 2008
    ....
  27. ncbi request reprint Higher-plant chloroplast and cytosolic 3-phosphoglycerate kinases: a case of endosymbiotic gene replacement
    H Brinkmann
    Institut fur Botanik, Technische Universitat Braunschweig, Germany
    Plant Mol Biol 30:65-75. 1996
    ..Evidence suggesting a eubacterial origin of plant genes for PGK via endosymbiotic gene replacement indicates that plant nuclear genomes are more highly chimaeric, i.e. contain more genes of eubacterial origin, than is generally assumed...
  28. ncbi request reprint Identification of prokaryotic homologues indicates an endosymbiotic origin for the alternative oxidases of mitochondria (AOX) and chloroplasts (PTOX)
    Ariane Atteia
    Institute of Botany III, Heinrich Heine University of Dusseldorf, Universitatsstrasse 1, D 40225 Dusseldorf, Germany
    Gene 330:143-8. 2004
    ..These findings suggest that the eukaryotic nuclear genes for the alternative oxidases of mitochondria and chloroplasts were acquired via endosymbiotic gene transfer from the eubacterial ancestors of these two organelles, respectively...
  29. ncbi request reprint Interspecific evolution: microbial symbiosis, endosymbiosis and gene transfer
    Meike Hoffmeister
    Institute of Botany III, University of Dusseldorf, Universitatsstrasse 1, D 40225 Dusseldorf, Germany
    Environ Microbiol 5:641-9. 2003
    ..In the case of chloroplasts and mitochondria, examples of recent and ancient gene transfer to the chromosomes of their host cell illustrate the process of genetic merger in the wake of organelle origins...
  30. ncbi request reprint How do mitochondrial genes get into the nucleus?
    K Henze
    Institute of Botany III, Universitat Dusseldorf, Universitatsstrasse 1, D 40225, Dusseldorf, Germany
    Trends Genet 17:383-7. 2001
    ..Direct DNA transfer, rather than cDNA-mediated transfer, does occur today, and it probably prevailed during the early phases of organelle evolution...
  31. ncbi request reprint Pyruvate : NADP+ oxidoreductase from the mitochondrion of Euglena gracilis and from the apicomplexan Cryptosporidium parvum: a biochemical relic linking pyruvate metabolism in mitochondriate and amitochondriate protists
    C Rotte
    , , , Germany
    Mol Biol Evol 18:710-20. 2001
    ..They are also consistent with the view that eukaryotic PFO domains are biochemical relics inherited from a facultatively anaerobic, eubacterial ancestor of mitochondria and hydrogenosomes...
  32. ncbi request reprint Pyruvate formate-lyase and a novel route of eukaryotic ATP synthesis in Chlamydomonas mitochondria
    Ariane Atteia
    Institute of Botany, University of Dusseldorf, 40225 Dusseldorf, Germany
    J Biol Chem 281:9909-18. 2006
    ..reinhardtii has the broadest repertoire of pyruvate-, ethanol-, and acetate-metabolizing enzymes described to date, many of which were previously viewed as specific to anaerobic eukaryotic lineages...
  33. ncbi request reprint How many genes in Arabidopsis come from cyanobacteria? An estimate from 386 protein phylogenies
    T Rujan
    Institute of Botany III, Universitat Dusseldorf, Universitatsstr 1, D 40225 Dusseldorf, Germany
    Trends Genet 17:113-20. 2001
    ..2%) of Arabidopsis nuclear genes stem from cyanobacteria. The degree of conservation preserved in protein sequences in addition to lateral gene transfer between free-living prokaryotes pose substantial challenges to genome phylogenetics...
  34. ncbi request reprint An overview of endosymbiotic models for the origins of eukaryotes, their ATP-producing organelles (mitochondria and hydrogenosomes), and their heterotrophic lifestyle
    W Martin
    , , Germany
    Biol Chem 382:1521-39. 2001
    ..Traditional models are contrasted to an alternative endosymbiotic model (the hydrogen hypothesis), which addresses the origin of heterotrophy and the origin of compartmentalized energy metabolism in eukaryotes...
  35. ncbi request reprint Genome history in the symbiotic hybrid Euglena gracilis
    Nahal Ahmadinejad
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Universitatsstr 1, 40225 Dusseldorf, Germany
    Gene 402:35-9. 2007
    ..A phylogenetic tree fails to account for this observation but the distribution of homologues and a phylogenetic network clearly show the common origin of E. gracilis from both kinetoplastid and photoautotrophic ancestors...
  36. ncbi request reprint Origins of hydrogenosomes and mitochondria
    C Rotte
    Institute of Botany, University of Dusseldorf, Universitatsstr 1, 40225, Dusseldorf, Germany
    Curr Opin Microbiol 3:481-6. 2000
    ..Available evidence suggests that a more in-depth understanding of the origins of eukaryotes and their organelles will hinge upon data from the genomes of protists that synthesize ATP without the need for oxygen...
  37. ncbi request reprint A novel prokaryotic trans-2-enoyl-CoA reductase from the spirochete Treponema denticola
    Sara Tucci
    Institute of Botany III, Heinrich Heine University of Duesseldorf, Universitaetsstrasse 1, 40225 Duesseldorf, Germany
    FEBS Lett 581:1561-6. 2007
    ....
  38. pmc Genome networks root the tree of life between prokaryotic domains
    Tal Dagan
    Institute of Botany III, Heinrich Heine University of Dusseldorf, Dusseldorf, Germany
    Genome Biol Evol 2:379-92. 2010
    ..The interdomain prokaryotic position of the root is thus not attributable to lineage-specific rate variation...
  39. pmc Modular networks and cumulative impact of lateral transfer in prokaryote genome evolution
    Tal Dagan
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Universitatsstrasse 1, 40225 Dusseldorf, Germany
    Proc Natl Acad Sci U S A 105:10039-44. 2008
    ....
  40. doi request reprint Variability of wax ester fermentation in natural and bleached Euglena gracilis Strains in response to oxygen and the elongase inhibitor flufenacet
    Sara Tucci
    Institute of Botany III, Heinrich Heine University of Duesseldorf, Universitaetsstrasse 1, 40225 Duesseldorf, Germany
    J Eukaryot Microbiol 57:63-9. 2010
    ..Addition of the elongase inhibitor flufenacet to the growth medium specifically reduced the accumulation of odd-numbered fatty acids and alcohols and tended to increase the overall yield of anaerobic wax esters...
  41. pmc Getting a better picture of microbial evolution en route to a network of genomes
    Tal Dagan
    Institute of Botany, University of Dusseldorf, Dusseldorf, Germany
    Philos Trans R Soc Lond B Biol Sci 364:2187-96. 2009
    ....
  42. doi request reprint Sulfide : quinone oxidoreductase (SQR) from the lugworm Arenicola marina shows cyanide- and thioredoxin-dependent activity
    Ursula Theissen
    Institute of Botany III, Heinrich Heine University of Duesseldorf, Universitaetsstrasse 1, Duesseldorf, Germany
    FEBS J 275:1131-9. 2008
    ..None of the mutant enzymes was active after expression in yeast, implicating these amino acids in the catalytic mechanism of the eukaryotic enzyme...
  43. doi request reprint Difficulties in testing for covarion-like properties of sequences under the confounding influence of changing proportions of variable sites
    Nicole Gruenheit
    Institute of Botany III, University of Dusseldorf, Dusseldorf, Germany
    Mol Biol Evol 25:1512-20. 2008
    ..Extreme intergroup differences in the extent of divergence and difference in proportions of variable sites could be contributing to this effect...
  44. pmc The tree of one percent
    Tal Dagan
    Institute of Botany, University of Dusseldorf, D 40225 Dusseldorf, Germany
    Genome Biol 7:118. 2006
    ..To incorporate such processes into the bigger picture of early evolution, biologists need to depart from the preconceived notion that all genomes are related by a single bifurcating tree...
  45. ncbi request reprint Purification, microsequencing and cloning of spinach ATP-dependent phosphofructokinase link sequence and function for the plant enzyme
    Christian Winkler
    Institute of Botany III, University of Dusseldorf, Germany
    FEBS J 274:429-38. 2007
    ....
  46. ncbi request reprint Archaebacteria (Archaea) and the origin of the eukaryotic nucleus
    William Martin
    Institut für Botanik III, Heinrich Heine Universitat Dusseldorf, Universitatsstrasse 1, 40225 Dusseldorf, Germany
    Curr Opin Microbiol 8:630-7. 2005
    ..Recent reports point to ways in which different ideas regarding the origin of the nucleus might someday be discriminated...
  47. ncbi request reprint Bifunctional aldehyde/alcohol dehydrogenase (ADHE) in chlorophyte algal mitochondria
    Ariane Atteia
    Departamento de Genetica Molecular, Instituto de Fisiologia Celular, Universidad Nacional Autáonoma de México, Mexico D F 04510, Mexico
    Plant Mol Biol 53:175-88. 2003
    ....
  48. ncbi request reprint Molecular diversity at 18 loci in 321 wild and 92 domesticate lines reveal no reduction of nucleotide diversity during Triticum monococcum (Einkorn) domestication: implications for the origin of agriculture
    B Kilian
    Institute of Botany III, Heinrich Heine Universitat Dusseldorf, Universitatsstrasse 1, 40225 Dusseldorf, Germany
    Mol Biol Evol 24:2657-68. 2007
    ..Taken together with archaeological findings from the Fertile Crescent, the data indicate that a specific wild einkorn race that arose without human intervention was subjected to multiple independent domestication events...
  49. ncbi request reprint Crystal ball. Getting a better picture of evolution
    William Martin
    University of Dusseldorf, Germany
    Environ Microbiol 7:479-80. 2005
  50. pmc Protein import into hydrogenosomes of Trichomonas vaginalis involves both N-terminal and internal targeting signals: a case study of thioredoxin reductases
    Marek Mentel
    Institute of Botany III, Heinrich Heine University of Duesseldorf, Duesseldorf, Germany
    Eukaryot Cell 7:1750-7. 2008
    ....
  51. pmc On the origin of biochemistry at an alkaline hydrothermal vent
    William Martin
    Institute of Botany, University of Dusseldorf, 40225 Dusseldorf, Germany
    Philos Trans R Soc Lond B Biol Sci 362:1887-925. 2007
    ....
  52. ncbi request reprint Evolutionary biology: Early evolution comes full circle
    William Martin
    Nature 431:134-7. 2004
  53. pmc Specific and differential inhibition of very-long-chain fatty acid elongases from Arabidopsis thaliana by different herbicides
    Sandra Trenkamp
    Bayer CropScience AG, Target Research, Building 6240, 40789 Monheim, Germany
    Proc Natl Acad Sci U S A 101:11903-8. 2004
    ....
  54. pmc Acceleration of genomic evolution caused by enhanced mutation rate in endocellular symbionts
    Takeshi Itoh
    Institute of Molecular Evolutionary Genetics and Department of Biology, Pennsylvania State University, 328 Mueller Laboratory, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 99:12944-8. 2002
    ..Rather, the elevated evolutionary rate appears to be mainly due to enhanced mutation rate, although the possibility of relaxation of purifying selection cannot be ruled out...
  55. pmc Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements
    Martin Wu
    The Institute for Genomic Research, Rockville, Maryland, USA
    PLoS Biol 2:E69. 2004
    ..With the availability of the complete genomes of both species and excellent genetic tools for the host, the wMel-D. melanogaster symbiosis is now an ideal system for studying the biology and evolution of Wolbachia infections...
  56. ncbi request reprint Mitochondria as we don't know them
    Aloysius G M Tielens
    Dept of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, PO Box 80176, The Netherlands
    Trends Biochem Sci 27:564-72. 2002
    ..Recent advances in understanding of mitochondrial biochemistry provide many surprises and furthermore, give insights into the evolutionary history of ATP-producing organelles...
  57. ncbi request reprint The smoking gun of gene transfer
    William Martin
    Nat Genet 33:442. 2003
  58. ncbi request reprint Evolutionary biology: essence of mitochondria
    Katrin Henze
    Nature 426:127-8. 2003
  59. ncbi request reprint Reading the entrails of chickens: molecular timescales of evolution and the illusion of precision
    Dan Graur
    Department of Biology and Biochemistry, University of Houston, Houston, TX 77204 5001, USA
    Trends Genet 20:80-6. 2004
    ..Were calibration and derivation uncertainties taken into proper consideration, the 95% confidence interval would have turned out to be at least 40 times larger ( approximately 14.2 billion years)...
  60. ncbi request reprint Endosymbiotic gene transfer: organelle genomes forge eukaryotic chromosomes
    Jeremy N Timmis
    School of Molecular and Biomedical Science, The University of Adelaide, South Australia 5005, Australia
    Nat Rev Genet 5:123-35. 2004
  61. pmc A unique set of 11,008 onion expressed sequence tags reveals expressed sequence and genomic differences between the monocot orders Asparagales and Poales
    Joseph C Kuhl
    Department of Horticulture, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Cell 16:114-25. 2004
    ..The Asparagales were more similar to eudicots than to the Poales for these genomic characteristics...
  62. ncbi request reprint Acetate:succinate CoA-transferase in the hydrogenosomes of Trichomonas vaginalis: identification and characterization
    Koen W A van Grinsven
    Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands
    J Biol Chem 283:1411-8. 2008
    ..Apparently, two completely different enzymes for succinate-dependent acetate production have evolved independently in ATP-generating organelles...
  63. ncbi request reprint Evolutionary dynamics of introns in plastid-derived genes in plants: saturation nearly reached but slow intron gain continues
    Malay Kumar Basu
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA
    Mol Biol Evol 25:111-9. 2008
    ..The overall pattern of intron gain and loss in the plastid-derived genes is shaped by this continuing gain and the more general tendency for loss that is characteristic of the recent evolution of plant genes...
  64. ncbi request reprint A positive definition of prokaryotes
    William Martin
    Nature 442:868. 2006
  65. ncbi request reprint The difference between organelles and endosymbionts
    Ursula Theissen
    Curr Biol 16:R1016-7; author reply R1017-8. 2006
  66. ncbi request reprint Eukaryotic evolution, changes and challenges
    T Martin Embley
    School of Biology, The Devonshire Building, University of Newcastle upon Tyne, Newcastle NE1 7RU, UK
    Nature 440:623-30. 2006
    ..But the evolutionary gap between prokaryotes and eukaryotes is now deeper, and the nature of the host that acquired the mitochondrion more obscure, than ever before...
  67. ncbi request reprint Evolutionary biology: out of thin air
    John F Allen
    Nature 445:610-2. 2007
  68. ncbi request reprint Testing hypotheses without considering predictions
    Tal Dagan
    Bioessays 29:500-3. 2007
  69. ncbi request reprint The evolution of eukaryotes
    William Martin
    Science 316:542-3; author reply 542-3. 2007
  70. ncbi request reprint Euglena gracilis ribonucleotide reductase: the eukaryote class II enzyme and the possible antiquity of eukaryote B12 dependence
    Eduard Torrents
    Department of Molecular Biology and Functional Genomics, Arrhenius Laboratories for Natural Sciences, Stockholm University, SE 10691 Stockholm, Sweden
    J Biol Chem 281:5604-11. 2006
    ....
  71. ncbi request reprint On the origin of genomes and cells within inorganic compartments
    Eugene V Koonin
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Trends Genet 21:647-54. 2005
    ....
  72. pmc Mutational decay and age of chloroplast and mitochondrial genomes transferred recently to angiosperm nuclear chromosomes
    Chun Y Huang
    Australian Centre for Plant Functional Genomics, School of Agriculture and Wine, University of Adelaide, Waite Campus, Glen Osmond, South Australia 5064, Australia
    Plant Physiol 138:1723-33. 2005
    ....
  73. ncbi request reprint Rate and polarity of gene fusion and fission in Oryza sativa and Arabidopsis thaliana
    Yoji Nakamura
    Division of Bioengineering and Bioinformatics, Graduate School of Information Science and Technology, Hokkaido University, Kita ku, Sapporo, Japan
    Mol Biol Evol 24:110-21. 2007
    ....
  74. ncbi request reprint Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice
    Julie A McMurry
    EpiVax Inc, 146 Clifford Street, Providence RI 02903, USA
    Curr Mol Med 7:351-68. 2007
    ..These experiments illustrate the use of immuno-informatics tools for vaccine development and describe a pathway for the development of a more effective, epitope-driven, immunotherapeutic vaccine for TB...
  75. ncbi request reprint Pathogenic archaebacteria: do they not exist because archaebacteria use different vitamins?
    William Martin
    Bioessays 26:592-3; author reply 593. 2004
  76. ncbi request reprint Engineering immunogenic consensus T helper epitopes for a cross-clade HIV vaccine
    Anne S De Groot
    TB HIV Research Lab, Brown University, Providence RI 02912, USA
    Methods 34:476-87. 2004
    ..These data confirm the utility of bioinformatics tools to select and construct novel "immunogenic consensus sequence" T cell epitopes for a globally relevant vaccine against HIV...
  77. ncbi request reprint Haplotype structure at seven barley genes: relevance to gene pool bottlenecks, phylogeny of ear type and site of barley domestication
    Benjamin Kilian
    Max Planck Institute for Plant Breeding Research, Carl von Linne Weg, 10, 50829, Koeln, Germany
    Mol Genet Genomics 276:230-41. 2006
    ....
  78. ncbi request reprint Evolution of the enzymes of the citric acid cycle and the glyoxylate cycle of higher plants. A case study of endosymbiotic gene transfer
    Claus Schnarrenberger
    Institut fur Biologie, Freie Universitat Berlin, Germany
    Eur J Biochem 269:868-83. 2002
    ....