J Heinrich

Summary

Country: Germany

Publications

  1. pmc FADS1 FADS2 gene cluster, PUFA intake and blood lipids in children: results from the GINIplus and LISAplus studies
    Marie Standl
    Institute of Epidemiology I, Helmholtz Zentrum München German Research Centre for Environmental Health, Neuherberg, Germany
    PLoS ONE 7:e37780. 2012
  2. pmc Children with ADHD symptoms have a higher risk for reading, spelling and math difficulties in the GINIplus and LISAplus cohort studies
    Darina Czamara
    Max Planck Institute of Psychiatry, Munich, Germany
    PLoS ONE 8:e63859. 2013
  3. pmc Physical activity and its correlates in children: a cross-sectional study (the GINIplus & LISAplus studies)
    Sandra Ortlieb
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Ingolstadter Landstrasse 1, Neuherberg 85764, Germany
    BMC Public Health 13:349. 2013
  4. pmc The association of smoking status with healthcare utilisation, productivity loss and resulting costs: results from the population-based KORA F4 study
    Margarethe Wacker
    Helmholtz Zentrum Munchen German Research Center for Environmental Health GmbH, Institute of Health Economics and Health Care Management, Member of the German Center for Lung Research, Comprehensive Pneumology Center Munich CPC M, Ingolstaedter Landstr, 1, Neuherberg 85764, Germany
    BMC Health Serv Res 13:278. 2013
  5. pmc Long-term exposure to NO2 and PM10 and all-cause and cause-specific mortality in a prospective cohort of women
    Joachim Heinrich
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health GmbH, Institute of Epidemiology I, Neuherberg, Germany
    Occup Environ Med 70:179-86. 2013
  6. doi request reprint [Two German Birth Cohorts: GINIplus and LISAplus]
    J Heinrich
    Deutsches Forschungszentrum für Gesundheit und Umwelt, Institut für Epidemiologie I, Helmholtz Zentrum Munchen, Ingolstadter Landstr 1, 85764, Neuherberg, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 55:864-74. 2012
  7. doi request reprint [Erfurt male cohort study (ERFORT study). Study design and selected results]
    J Heinrich
    Institut für Epidemiologie I, Helmholtz Zentrum Munchen, Ingolstadter Landstr 1, 85764, Neuherberg, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 55:801-8. 2012
  8. pmc Early life risk factors of being overweight at 10 years of age: results of the German birth cohorts GINIplus and LISAplus
    Z Pei
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Neuherberg, Germany
    Eur J Clin Nutr 67:855-62. 2013
  9. doi request reprint FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children
    M Standl
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Munich, Germany
    Clin Exp Allergy 41:1757-66. 2011
  10. doi request reprint Perinatal exposure to endotoxin and the development of eczema during the first 6 years of life
    C M Chen
    Helmholtz Centre Munich, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Dermatol 35:238-44. 2010

Collaborators

Detail Information

Publications77

  1. pmc FADS1 FADS2 gene cluster, PUFA intake and blood lipids in children: results from the GINIplus and LISAplus studies
    Marie Standl
    Institute of Epidemiology I, Helmholtz Zentrum München German Research Centre for Environmental Health, Neuherberg, Germany
    PLoS ONE 7:e37780. 2012
    ..Our aim was to investigate whether lipid levels are determined by the FADS genotype already in children and whether this association interacts with dietary intake of n-3 fatty acids...
  2. pmc Children with ADHD symptoms have a higher risk for reading, spelling and math difficulties in the GINIplus and LISAplus cohort studies
    Darina Czamara
    Max Planck Institute of Psychiatry, Munich, Germany
    PLoS ONE 8:e63859. 2013
    ..Our results strengthen the hypothesis that ADHD and learning disorders are comorbid and share, at least partially, the same underlying process. Up to date, it is not clear, on which exact functional processes this comorbidity is based...
  3. pmc Physical activity and its correlates in children: a cross-sectional study (the GINIplus & LISAplus studies)
    Sandra Ortlieb
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Ingolstadter Landstrasse 1, Neuherberg 85764, Germany
    BMC Public Health 13:349. 2013
    ..This cross-sectional study examined the associations of PA with individual (biological, social, behavioral, psychological) and environmental (East vs. West Germany, rural vs. urban regions) characteristics in children...
  4. pmc The association of smoking status with healthcare utilisation, productivity loss and resulting costs: results from the population-based KORA F4 study
    Margarethe Wacker
    Helmholtz Zentrum Munchen German Research Center for Environmental Health GmbH, Institute of Health Economics and Health Care Management, Member of the German Center for Lung Research, Comprehensive Pneumology Center Munich CPC M, Ingolstaedter Landstr, 1, Neuherberg 85764, Germany
    BMC Health Serv Res 13:278. 2013
    ..This population-based cross-sectional study compares healthcare utilisation, direct medical costs, and costs of productivity losses for different smoking groups: current smokers, former smokers, and never smokers...
  5. pmc Long-term exposure to NO2 and PM10 and all-cause and cause-specific mortality in a prospective cohort of women
    Joachim Heinrich
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health GmbH, Institute of Epidemiology I, Neuherberg, Germany
    Occup Environ Med 70:179-86. 2013
    ..These associations were temporally stable. Long-term exposure to ambient PM(10) and NO(2) was associated with increased mortality rates...
  6. doi request reprint [Two German Birth Cohorts: GINIplus and LISAplus]
    J Heinrich
    Deutsches Forschungszentrum für Gesundheit und Umwelt, Institut für Epidemiologie I, Helmholtz Zentrum Munchen, Ingolstadter Landstr 1, 85764, Neuherberg, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 55:864-74. 2012
    ..These data were included in many international projects and consortia for purposes of international comparisons of prevalence and consistency of findings, and to increase the power of the analyses...
  7. doi request reprint [Erfurt male cohort study (ERFORT study). Study design and selected results]
    J Heinrich
    Institut für Epidemiologie I, Helmholtz Zentrum Munchen, Ingolstadter Landstr 1, 85764, Neuherberg, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 55:801-8. 2012
    ..This paper describes the study design, descriptive data on cardiovascular and psychosocial factors at baseline survey and findings of three 5-year follow-up medical examinations...
  8. pmc Early life risk factors of being overweight at 10 years of age: results of the German birth cohorts GINIplus and LISAplus
    Z Pei
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Neuherberg, Germany
    Eur J Clin Nutr 67:855-62. 2013
    ..To develop a prediction model that quantifies the risk of being overweight at 10 years of age...
  9. doi request reprint FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children
    M Standl
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Munich, Germany
    Clin Exp Allergy 41:1757-66. 2011
    ..The association between dietary fatty acid intake and the development of atopic diseases has been inconsistent. This could be due to inter-individual genetic differences in fatty acid metabolism...
  10. doi request reprint Perinatal exposure to endotoxin and the development of eczema during the first 6 years of life
    C M Chen
    Helmholtz Centre Munich, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Dermatol 35:238-44. 2010
    ..Previous studies have reported a protective association between high levels of exposure to endotoxin during infancy and the development of subsequent eczema within the first 6 months of life...
  11. ncbi request reprint Respiratory symptoms in relation to indoor exposure to mite and cat allergens and endotoxins. Indoor Factors and Genetics in Asthma (INGA) Study Group
    U Gehring
    GSF-National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 18:555-63. 2001
    ..The risk is increased if subjects are exposed to a mixture of allergens or if they are sensitized in addition to high exposure...
  12. ncbi request reprint Exposure to endotoxin decreases the risk of atopic eczema in infancy: a cohort study
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    J Allergy Clin Immunol 108:847-54. 2001
    ....
  13. doi request reprint FADS gene cluster modulates the effect of breastfeeding on asthma. Results from the GINIplus and LISAplus studies
    M Standl
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology I, Ingolstadter Landstrasse 1, Neuherberg, Germany
    Allergy 67:83-90. 2012
    ..Therefore, we evaluated the influence of the FADS1 FADS2 gene cluster polymorphisms on the association between BF and asthma...
  14. doi request reprint Common variants in FCER1A influence total serum IgE levels from cord blood up to six years of life
    C M Chen
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 64:1327-32. 2009
    ..In a recent genome wide scan, a functional promoter variant (rs2251746) in the gene encoding the alpha chain of the high affinity receptor for immunoglobulin E (IgE) (FCER1A) was identified as major determinant of serum IgE levels...
  15. pmc Beta(1-->3)-glucan in house dust of German homes: housing characteristics, occupant behavior, and relations with endotoxins, allergens, and molds
    U Gehring
    GSF - National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Environ Health Perspect 109:139-44. 2001
    ..4). We conclude that that the amount of dust sampled can be used as a proxy for hygiene and that beta(1-->3)-glucan concentrations per square meter are related to the amount of dust sampled...
  16. ncbi request reprint Exposure to house dust endotoxin and allergic sensitization in adults
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 59:946-52. 2004
    ..It has been suggested that exposure to elevated levels of endotoxin decreases the risk of allergic sensitization...
  17. doi request reprint Respiratory health in children, and indoor exposure to (1,3)-β-D-glucan, EPS mould components and endotoxin
    C Tischer
    Institute of EpidemiologyHelmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany
    Eur Respir J 37:1050-9. 2011
    ..The reasons for the differences between countries are not clear...
  18. doi request reprint Growth of infants fed formula rich in canola oil (low erucic acid rapeseed oil)
    Peter Rzehak
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Nutr 30:339-45. 2011
    ..The aim of this study is to investigate whether infant formulas containing canola oil support normal growth in infants as assessed by weight and length gain...
  19. doi request reprint Regional and socio-economic differences in food, nutrient and supplement intake in school-age children in Germany: results from the GINIplus and the LISAplus studies
    Stefanie Sausenthaler
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstadter Landstr 1, 85764 Neuherberg, Germany
    Public Health Nutr 14:1724-35. 2011
    ..To describe regional differences between eastern and western Germany with regard to food, nutrient and supplement intake in 9-12-year-old children, and analyse its association with parental education and equivalent income...
  20. pmc Respiratory health and individual estimated exposure to traffic-related air pollutants in a cohort of young children
    V Morgenstern
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Occup Environ Med 64:8-16. 2007
    ....
  21. doi request reprint Glutathione-S-transferase P1, early exposure to mould in relation to respiratory and allergic health outcomes in children from six birth cohorts. A meta-analysis
    C G Tischer
    Helmholtz Centre Munich, German Research Centre for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany
    Allergy 68:339-46. 2013
    ..It has been suggested that functional polymorphisms of the GSTP1 gene may influence the risk for allergic disorders through an impaired defence against oxidant injury...
  22. doi request reprint Prenatal and postnatal tobacco smoke exposure and development of insulin resistance in 10 year old children
    Elisabeth Thiering
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Int J Hyg Environ Health 214:361-8. 2011
    ..Positive dose-dependent associations and independent effects of postnatal exposure suggest involvement of environmental tobacco smoke in the risk for development of insulin resistance in children...
  23. ncbi request reprint Increasing prevalence of bronchial hyperresponsiveness in three selected areas in East Germany. Bitterfeld Study Group
    C Frye
    , Institut fur Epidemiologie, Neuherberg, Germany
    Eur Respir J 18:451-8. 2001
    ..The present results give indirect evidence, that less respiratory infections may be associated with higher bronchial hyperresponsiveness...
  24. doi request reprint Associations between BMI and the FTO gene are age dependent: results from the GINI and LISA birth cohort studies up to age 6 years
    Peter Rzehak
    Institute of Epidemiology, German Research Center for Environmental Health, Helmholtz Zentrum Munchen, Neuherberg, Germany
    Obes Facts 3:173-80. 2010
    ..However, little is known about the longitudinal dynamics of these polymorphisms on body mass index (BMI), overweight, and obesity...
  25. doi request reprint Growth velocity during infancy and onset of asthma in school-aged children
    C Flexeder
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Neuherberg, Germany
    Allergy 67:257-64. 2012
    ..This study examines the association between peak height and weight velocities during the first 2 years of life and onset of asthma and wheeze up to 10 years of age...
  26. ncbi request reprint Social factors, allergen, endotoxin, and dust mass in mattress
    C M Chen
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Indoor Air 17:384-93. 2007
    ..The observed negative association between cat allergen loads and concentrations in mattress and family SES in non-cat owners' homes indicated that community is an important source of cat allergen exposure...
  27. ncbi request reprint Predictors of group 5 grass-pollen allergens in settled house dust: comparison between pollination and nonpollination seasons
    B Fahlbusch
    Friedrich-Schiller-University, Institute of Clinical Immunology, Jena, GSF - National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 56:1081-6. 2001
    ..The removal of dust by frequent cleaning reduces the indoor exposure to grass allergens. Such information is essential to train patients in allergen avoidance...
  28. pmc Long-term exposure to traffic-related air pollution and insulin resistance in children: results from the GINIplus and LISAplus birth cohorts
    E Thiering
    German Research Center for Environmental Health, Neuherberg, Germany
    Diabetologia 56:1696-704. 2013
    ..We aimed to assess the association between traffic-related air pollution and insulin resistance in children...
  29. ncbi request reprint Repeated measurements of allergens and endotoxin in settled house dust over a time period of 6 years
    R Topp
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Allergy 33:1659-66. 2003
    ..This singly measured biocontaminant concentration is related to adverse respiratory outcomes such as asthma, wheeze or others...
  30. ncbi request reprint Health impacts of second-hand exposure to cat allergen Fel d 1 in infants
    A Heissenhuber
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 58:154-7. 2003
    ..Therefore we restricted our analysis to infants without a cat at home since birth...
  31. ncbi request reprint Predictivity of allergic sensitization (RAST) for the onset of allergic diseases in adults
    Y Schoefer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 63:81-6. 2008
    ..Specific IgE antibodies are often detected without any clinical manifestation of allergies. We aimed to analyse the predictivity of allergic sensitization for incident symptoms of allergic diseases in adults during a 10-year follow-up...
  32. ncbi request reprint Stress-related maternal factors during pregnancy in relation to childhood eczema: results from the LISA Study
    S Sausenthaler
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    J Investig Allergol Clin Immunol 19:481-7. 2009
    ..Stress has been suggested to impact the onset and exacerbation of eczema and other atopic disorders. Whether early exposure to stress-related factors might exert long-term effects remains to be clarified...
  33. ncbi request reprint The distribution in specific IgE and the prevalence of allergic symptoms in 25-64-years old inhabitants of an eastern and a western German city--results from Augsburg and Erfurt
    B Filipiak
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Eur J Epidemiol 17:77-84. 2001
    ..The purpose of this study was to replicate these findings using data from Augsburg, a city from the southern part of West Germany. Furthermore the study population in this analysis was extended to higher age groups...
  34. ncbi request reprint Farming, rural lifestyle and atopy in adults from southern Germany--results from the MONICA/KORA study Augsburg
    B Filipiak
    GSF National Reseach Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Allergy 31:1829-38. 2001
    ..We compared the prevalence of allergic diseases in farmers, and rural, suburban and urban residents in the small geographical area of Augsburg in southern Germany...
  35. ncbi request reprint Levels and predictors of endotoxin in mattress dust samples from East and West German homes
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Indoor Air 14:284-92. 2004
    ..None of these factors explains the difference in infant's mattress dust endotoxin between Leipzig and Munich or could be used as a surrogate for endotoxin...
  36. doi request reprint Atopic diseases, allergic sensitization, and exposure to traffic-related air pollution in children
    Verena Morgenstern
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, D 85764 Neuherberg, Germany
    Am J Respir Crit Care Med 177:1331-7. 2008
    ..In vitro studies, animal experiments, and human exposure studies have shown how ambient air pollution increases the risk of atopic diseases. However, results derived from observational studies are inconsistent...
  37. ncbi request reprint PM25 measurements in ambient aerosol: comparison between Harvard impactor (HI) and the tapered element oscillating microbalance (TEOM) system
    J Cyrys
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Sci Total Environ 278:191-7. 2001
    ..10 x HI - 0.668. Because the measured levels of ammonium nitrate were very low in Erfurt, we concluded that other compounds like semi-volatile organics were responsible for the loss of particulate material at 50 degrees C...
  38. ncbi request reprint Sources and concentrations of indoor nitrogen dioxide in Hamburg (west Germany) and Erfurt (east Germany)
    J Cyrys
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Sci Total Environ 250:51-62. 2000
    ..This variable caused a similar increase in the indoor NO2 levels in each city (43% in Erfurt and 47% in Hamburg). However, outdoor sources of NO2 (motor vehicle traffic) contributed more to indoor NO2 levels in Hamburg than in Erfurt...
  39. ncbi request reprint Factors affecting lead and cadmium levels in house dust in industrial areas of eastern Germany
    I Meyer
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Sci Total Environ 234:25-36. 1999
    ....
  40. ncbi request reprint Weight gain in two adult cohorts in East and West Germany reunification
    K Wimmer
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Cent Eur J Public Health 11:202-8. 2003
    ..If different lifestyle factors after German division contribute to these differences, one might speculate that trends of obesity and overweight in the East and West after German reunification in 1990 would be similar...
  41. ncbi request reprint Vaccination against Haemophilus influenzae type b and atopy in east German schoolchildren
    B Laubereau
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Eur J Med Res 7:387-92. 2002
    ..In this paper we investigated the association of Haemophilus influenzae type b (Hib)-vaccination and atopic diseases and allergic sensitisation in children in Eastern Germany...
  42. ncbi request reprint Elemental composition and sources of fine and ultrafine ambient particles in Erfurt, Germany
    J Cyrys
    GSF, National Research Center for Environment and Health, Institute of Epidemiology, Geb 56, O 85764, Neuherberg, Germany
    Sci Total Environ 305:143-56. 2003
    ..Sulfur could be a tracer for coal combustion, however, it was not correlated with any of the quoted elements. Highly correlated elements V and Ni have similar enrichment factors and are considered as tracers for oil combustion...
  43. ncbi request reprint The effect of low-level blood lead on hematologic parameters in children
    B Jacob
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Ingolstadter Landstrasse 1, Neuherberg, D 85758, Germany
    Environ Res 82:150-9. 2000
    ..The reasons for our observation, especially the gender difference, are still uncertain. In conclusion the morphology and function of erythrocytes might be sensitive parameters of low dose lead toxicity...
  44. ncbi request reprint Inverse social gradient of secondary immune response parameters in children
    G Bolte
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Rev Environ Health 14:135-43. 1999
    ..The aim of our study was to assess the relation between social class, immune parameters, and the prevalence of respiratory infections in children...
  45. doi request reprint Prospective association between food sensitization and food allergy: results of the LISA birth cohort study
    E Schnabel
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Allergy 40:450-7. 2010
    ..Food allergy is common, especially in childhood, where 6-8% of children are affected. Identification of early and efficient markers for later development of food allergy is very important...
  46. ncbi request reprint Trends in prevalence of atopic diseases and allergic sensitization in children in Eastern Germany
    J Heinrich
    GSF National Research Centre for Environment and Health Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 19:1040-6. 2002
    ....
  47. ncbi request reprint Indoor and outdoor BTX levels in German cities
    P Schneider
    GSF-National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Sci Total Environ 267:41-51. 2001
    ..The strong and yet undiscovered indoor source for toluene in East Germany might lead to a further increase in the indoor air load in those homes in the East, which undergo renovations which will lead to improved insulation...
  48. ncbi request reprint Margarine consumption and allergy in children
    G Bolte
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Am J Respir Crit Care Med 163:277-9. 2001
    ..Increased intake of certain polyunsaturated fatty acids might further stimulate IgE production in boys...
  49. ncbi request reprint Maternal oral contraceptive use and atopic diseases in the offspring
    C Frye
    GSF National Research Center for Environment and Health Institute of Epidemiology, Neuherberg, Germany
    Allergy 58:229-32. 2003
    ..This study examined the association of maternal oral contraceptive (OC) use - before and after birth - and atopic manifestations in the offspring...
  50. ncbi request reprint Gas cooking, respiratory health and white blood cell counts in children
    B Hölscher
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Int J Hyg Environ Health 203:29-37. 2000
    ..91-2.10). The strongest effect estimates for chronic inflammation were found for those children likely to have been exposed at higher levels, that is when stoves had no fans, in smaller homes, and for children spending more time indoors...
  51. ncbi request reprint Parental education and children's respiratory and allergic symptoms in the Pollution and the Young (PATY) study
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 27:95-107. 2006
    ..However, differences remained after adjusting for these variables. Children's health was associated with parental education. The association could not fully be explained by established risk factors...
  52. ncbi request reprint Food and fatty acid intake and atopic disease in adults
    M A Trak-Fellermeier
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Postfach 11 29, D 85758 Oberschleissheim, Germany
    Eur Respir J 23:575-82. 2004
    ..Dietary factors were mostly not related with prevalence rates of bronchial hyperresponsiveness and atopic eczema either in males or in females...
  53. ncbi request reprint Trends in food intake in adults from the city of Erfurt before and after the German reunification
    G Winkler
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Ann Nutr Metab 41:283-90. 1997
    ..180 g; 209 vs. 174 g and 62 vs. 53 g. Surprisingly similar changes in eating habits were observed with men and women. The majority of changes could be explained by the improved variety in food supply after the reunification...
  54. doi request reprint Meta-analysis of mould and dampness exposure on asthma and allergy in eight European birth cohorts: an ENRIECO initiative
    C G Tischer
    Helmholtz Centre Munich, German Research Centre for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany
    Allergy 66:1570-9. 2011
    ..Several cross-sectional studies during the past 10 years have observed an increased risk of allergic outcomes for children living in damp or mouldy environments...
  55. ncbi request reprint The association between baseline lung function and bronchial responsiveness to methacholine
    G Wassmer
    GSF, Institut fur Epidemiologie, Neuherberg, Germany
    Eur J Med Res 2:47-54. 1997
    ..Furthermore, our data support the superiority of the dose response slope for the analysis of bronchial responsiveness in epidemiologic surveys...
  56. ncbi request reprint The effect of environmental tobacco smoke exposure on allergic sensitization and allergic rhinitis in adults
    R Topp
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, Neuherberg, Germany
    Indoor Air 15:222-7. 2005
    ..In this work, we assess the association between exposure to environmental tobacco smoke (ETS) at home or at work, and allergic sensitization and allergic rhinitis in 4093 German adults...
  57. pmc Gender differences in lung cancer risk by smoking: a multicentre case-control study in Germany and Italy
    M Kreuzer
    GSF Institute of Epidemiology, Neuherberg, Germany
    Br J Cancer 82:227-33. 2000
    ..We conclude that for comparable exposure to tobacco smoke, the risk of lung cancer is comparable in women and men...
  58. pmc Associations between mortality and air pollution in central Europe
    A Peters
    GSF National Research Center for Environment and Health, Neuherberg, Germany
    Environ Health Perspect 108:283-7. 2000
    ....
  59. ncbi request reprint Trends and predictors of overweight and obesity in East German children
    C Frye
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Int J Obes Relat Metab Disord 27:963-9. 2003
    ..Therefore, we analyzed trends in overweight and obesity in East German school children...
  60. doi request reprint Association between domestic mould and mould components, and asthma and allergy in children: a systematic review
    C Tischer
    Institute of Epidemiology, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Ingolstaedter Landstrasse 1, D 85764, Neuherberg, Germany
    Eur Respir J 38:812-24. 2011
    ..In order to disentangle the different effects of overall microbial exposure on children's health, research should focus on specific microbial markers in the home, in combination with new assessment techniques including molecular methods...
  61. ncbi request reprint Decline of ambient air pollution and respiratory symptoms in children
    J Heinrich
    Forschungszentrum für Umwelt und Gesundheit, Institut fuer Epidemiologie, and Lehrstuhl für Epidemiologie, Ludwig Maximilians Universitaet München, Neuherberg, Germany
    Am J Respir Crit Care Med 161:1930-6. 2000
    ..76; CI: 0.66 to 0.88) after adjustment for several potential predictors. In conclusion, we found that the prevalence of nonasthmatic respiratory symptoms decreased from the first period to the second period in all three study areas...
  62. doi request reprint Geographical variation and the determinants of domestic endotoxin levels in mattress dust in Europe
    C M Chen
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Indoor Air 22:24-32. 2012
    ..The observed variation needs to be taken into account when evaluating the health effects of endotoxin exposures in international contexts...
  63. ncbi request reprint Arsenic burden among children in industrial areas of eastern Germany
    M J Trepka
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Sci Total Environ 180:95-105. 1996
    ..59 micrograms As/g creatinine; 95% C.I. 4.20-5.02). This suggests that the arsenic contamination in Hettstedt is not substantially increasing the internal burden of arsenic among children above that found in other German children...
  64. doi request reprint Peer problems are associated with elevated serum leptin levels in children
    G Kohlboeck
    Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany
    Psychol Med 44:255-65. 2014
    ..This study aimed to assess the association between emotional symptoms and peer problems and serum leptin levels in children aged 10 years of the two population-based GINI-plus and LISA-plus birth cohorts...
  65. doi request reprint Is a child's growth pattern early in life related to serum adipokines at the age of 10 years?
    C Flexeder
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany
    Eur J Clin Nutr 68:25-31. 2014
    ..This study investigates the association between peak growth velocities, body mass index (BMI) and age at adiposity rebound (AR), with leptin and adiponectin levels at age 10 years...
  66. doi request reprint Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma
    J S Ried
    Institute of Genetic Epidemiology, Helmholtz Zentrum Munchen German Research Center for Environmental Health, Neuherberg, Germany
    Allergy 68:629-36. 2013
    ..This work aimed to investigate the interrelation of current asthma, candidate asthma risk alleles and a panel of metabolites...
  67. doi request reprint Short- and long-term effects of feeding hydrolyzed protein infant formulas on growth at < or = 6 y of age: results from the German Infant Nutritional Intervention Study
    Peter Rzehak
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Am J Clin Nutr 89:1846-56. 2009
    ..The short- and long-term effects of feeding with hydrolyzed formulas on growth are uncertain...
  68. ncbi request reprint Increased asthma medication use in association with ambient fine and ultrafine particles
    S von Klot
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 20:691-702. 2002
    ..The results suggest that reported asthma medication use and symptoms increase in association with particulate air pollution and gaseous pollutants such as nitrogen dioxide...
  69. ncbi request reprint Serum immunoglobulin level and skin prick test response
    M Wjst
    GSF Forschungszentrum fuer Umwelt und Gesundheit, Institut fuer Epidemiologie, Ingolstaedter Landstrasse 1, Neuherberg, D 85758, Germany
    Eur J Med Res 2:177-81. 1997
    ..Methods: In a population-based study of 2,470 children, 2,188 skin prick tests, and 2,042 blood samples could be analyzed...
  70. ncbi request reprint Allergic sensitization and diet: ecological analysis in selected European cities
    J Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 17:395-402. 2001
    ..59, p = 0.035). These results support the hypothesis that a high intake of monounsaturated fatty acids might promote the development of allergic sensitization...
  71. ncbi request reprint Influence of physical inactivity on the prevalence of hay fever
    Y Kohlhammer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 61:1310-5. 2006
    ..While treatments are improving, the main cause for an increasing trend of hay fever and its definite triggers remain unclear. The aim of our study was to assess whether physical inactivity could be a risk factor for hay fever...
  72. ncbi request reprint Biomarkers of exposure to passive smoking of school children: frequency and determinants
    A Thaqi
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstädter Landstrasse, Neuherberg, Germany
    Indoor Air 15:302-10. 2005
    ..Children exposed to parental smoke showed much higher biomarker levels than the non-smoking spouse of an adult smoker. Therefore, children need specifically protection from ETS at home...
  73. ncbi request reprint Development of relative weight, overweight and obesity from childhood to young adulthood. A longitudinal analysis of individual change of height and weight
    P Rzehak
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Ingolstaedter Landstrasse 1, D 85764, Neuherberg, Germany
    Eur J Epidemiol 21:661-72. 2006
    ..To investigate individual longitudinal change of relative weight, overweight and obesity from age 5 to 25 years by gender...
  74. ncbi request reprint Swimming pool attendance and hay fever rates later in life
    Y Kohlhammer
    GSF, National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 61:1305-9. 2006
    ..The aim of our study was to assess whether pool attendance in childhood would be related to higher rates of allergic diseases in adulthood, with special regard to hay fever...
  75. pmc Variants of the FADS1 FADS2 gene cluster, blood levels of polyunsaturated fatty acids and eczema in children within the first 2 years of life
    Peter Rzehak
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    PLoS ONE 5:e13261. 2010
    ..We analyze this genetic-association in two children-cohort-studies. In addition, the association between variants in the FADS-gene-cluster and blood-fatty-acid-composition with eczema was studied...
  76. ncbi request reprint Asthma is associated with single-nucleotide polymorphisms in ADAM33
    M Werner
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Ingolstaedter Landstrasse, Neuherberg, Germany
    Clin Exp Allergy 34:26-31. 2004
    ..The ADAM33 gene has recently been associated with asthma and bronchial hyper-reactivity. It codes for a disintegrin and metalloproteinase that triggers intra- and extracellular signalling by protein shedding...