J Heinrich

Summary

Country: Germany

Publications

  1. pmc Environmental exposure assessment in European birth cohorts: results from the ENRIECO project
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Environ Health 12:8. 2013
  2. pmc Exposure to second-hand smoke and direct healthcare costs in children - results from two German birth cohorts, GINIplus and LISAplus
    Ariane Batscheider
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Health Economics and Health Care Management, Member of the German Center for Lung Research, Neuherberg, Germany
    BMC Health Serv Res 12:344. 2012
  3. pmc Transient receptor potential genes, smoking, occupational exposures and cough in adults
    Lidwien A M Smit
    INSERM, CESP Centre for research in Epidemiology and Population Health, U1018, Respiratory and environmental epidemiology Team, Villejuif F 94807, France
    Respir Res 13:26. 2012
  4. pmc High blood pressure, antihypertensive medication and lung function in a general adult population
    Eva Schnabel
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Respir Res 12:50. 2011
  5. pmc Regional differences in prediction models of lung function in Germany
    Eva Schnabel
    Helmholtz Zentrum Munchen, Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Respir Res 11:40. 2010
  6. pmc Short-term effects of air pollution: a panel study of blood markers in patients with chronic pulmonary disease
    Katharina Hildebrandt
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Munich, Germany
    Part Fibre Toxicol 6:25. 2009
  7. pmc A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS)
    Francesc Castro-Giner
    Public Health and Epidemiology Network Biomedical Research Center, Barcelona, Spain
    BMC Med Genet 10:128. 2009
  8. doi request reprint Influence of indoor factors in dwellings on the development of childhood asthma
    Joachim Heinrich
    Helmholtz Zentrum Munchen, National Research Center for Environmental Health, Institute of Epidemiology, Munich, Germany
    Int J Hyg Environ Health 214:1-25. 2011
  9. doi request reprint Respiratory health in children, and indoor exposure to (1,3)-β-D-glucan, EPS mould components and endotoxin
    C Tischer
    Institute of EpidemiologyHelmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany
    Eur Respir J 37:1050-9. 2011
  10. doi request reprint Road traffic noise: self-reported noise annoyance versus GIS modelled road traffic noise exposure
    Matthias Birk
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany
    J Environ Monit 13:3237-45. 2011

Collaborators

Detail Information

Publications142 found, 100 shown here

  1. pmc Environmental exposure assessment in European birth cohorts: results from the ENRIECO project
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Environ Health 12:8. 2013
    ....
  2. pmc Exposure to second-hand smoke and direct healthcare costs in children - results from two German birth cohorts, GINIplus and LISAplus
    Ariane Batscheider
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Health Economics and Health Care Management, Member of the German Center for Lung Research, Neuherberg, Germany
    BMC Health Serv Res 12:344. 2012
    ..The aim of this study was to estimate excess healthcare costs of exposure to tobacco smoke in German children...
  3. pmc Transient receptor potential genes, smoking, occupational exposures and cough in adults
    Lidwien A M Smit
    INSERM, CESP Centre for research in Epidemiology and Population Health, U1018, Respiratory and environmental epidemiology Team, Villejuif F 94807, France
    Respir Res 13:26. 2012
    ..The aim was to study the influence of single nucleotide polymorphisms (SNPs) in TRP genes and irritant exposures on cough...
  4. pmc High blood pressure, antihypertensive medication and lung function in a general adult population
    Eva Schnabel
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Respir Res 12:50. 2011
    ..Thus, aim of this analysis is to determine whether hypertension and antihypertensive medication have an adverse effect on lung function in a general adult population...
  5. pmc Regional differences in prediction models of lung function in Germany
    Eva Schnabel
    Helmholtz Zentrum Munchen, Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Respir Res 11:40. 2010
    ..The aim of this analysis was to determine whether lung function determinants differ between subpopulations within Germany and whether prediction equations developed for one subpopulation are also adequate for another subpopulation...
  6. pmc Short-term effects of air pollution: a panel study of blood markers in patients with chronic pulmonary disease
    Katharina Hildebrandt
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Munich, Germany
    Part Fibre Toxicol 6:25. 2009
    ..abstract:..
  7. pmc A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS)
    Francesc Castro-Giner
    Public Health and Epidemiology Network Biomedical Research Center, Barcelona, Spain
    BMC Med Genet 10:128. 2009
    ..First, we assessed all markers in a subset of subjects using DNA pooling, and in a second stage we evaluated the most promising markers at an individual level...
  8. doi request reprint Influence of indoor factors in dwellings on the development of childhood asthma
    Joachim Heinrich
    Helmholtz Zentrum Munchen, National Research Center for Environmental Health, Institute of Epidemiology, Munich, Germany
    Int J Hyg Environ Health 214:1-25. 2011
    ..More research is also needed to clarify the potential risk for exposure to volatile and semi-volatile organic compounds due to renovation activities, phthalates and chlorine chemicals due to cleaning...
  9. doi request reprint Respiratory health in children, and indoor exposure to (1,3)-β-D-glucan, EPS mould components and endotoxin
    C Tischer
    Institute of EpidemiologyHelmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany
    Eur Respir J 37:1050-9. 2011
    ..The reasons for the differences between countries are not clear...
  10. doi request reprint Road traffic noise: self-reported noise annoyance versus GIS modelled road traffic noise exposure
    Matthias Birk
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany
    J Environ Monit 13:3237-45. 2011
    ..The aim of this study was to analyse the association between noise exposure due to neighbouring road traffic and the noise annoyance of adults, taking other determinants into consideration...
  11. ncbi request reprint Pets and vermin are associated with high endotoxin levels in house dust
    J Heinrich
    GSF, Institute of Epidemiology, Munich, Germany
    Clin Exp Allergy 31:1839-45. 2001
    ..A higher microbial exposure in general and in particular to endotoxin in early childhood might contribute to this lower risk of atopy...
  12. ncbi request reprint Respiratory symptoms in relation to indoor exposure to mite and cat allergens and endotoxins. Indoor Factors and Genetics in Asthma (INGA) Study Group
    U Gehring
    GSF-National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 18:555-63. 2001
    ..The risk is increased if subjects are exposed to a mixture of allergens or if they are sensitized in addition to high exposure...
  13. doi request reprint Perinatal exposure to endotoxin and the development of eczema during the first 6 years of life
    C M Chen
    Helmholtz Centre Munich, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Dermatol 35:238-44. 2010
    ..Previous studies have reported a protective association between high levels of exposure to endotoxin during infancy and the development of subsequent eczema within the first 6 months of life...
  14. pmc Beta(1-->3)-glucan in house dust of German homes: housing characteristics, occupant behavior, and relations with endotoxins, allergens, and molds
    U Gehring
    GSF - National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Environ Health Perspect 109:139-44. 2001
    ..4). We conclude that that the amount of dust sampled can be used as a proxy for hygiene and that beta(1-->3)-glucan concentrations per square meter are related to the amount of dust sampled...
  15. doi request reprint FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children
    M Standl
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Munich, Germany
    Clin Exp Allergy 41:1757-66. 2011
    ..The association between dietary fatty acid intake and the development of atopic diseases has been inconsistent. This could be due to inter-individual genetic differences in fatty acid metabolism...
  16. doi request reprint FADS gene cluster modulates the effect of breastfeeding on asthma. Results from the GINIplus and LISAplus studies
    M Standl
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology I, Ingolstadter Landstrasse 1, Neuherberg, Germany
    Allergy 67:83-90. 2012
    ..Therefore, we evaluated the influence of the FADS1 FADS2 gene cluster polymorphisms on the association between BF and asthma...
  17. ncbi request reprint Exposure to endotoxin decreases the risk of atopic eczema in infancy: a cohort study
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    J Allergy Clin Immunol 108:847-54. 2001
    ....
  18. doi request reprint Growth of infants fed formula rich in canola oil (low erucic acid rapeseed oil)
    Peter Rzehak
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Nutr 30:339-45. 2011
    ..The aim of this study is to investigate whether infant formulas containing canola oil support normal growth in infants as assessed by weight and length gain...
  19. doi request reprint Regional and socio-economic differences in food, nutrient and supplement intake in school-age children in Germany: results from the GINIplus and the LISAplus studies
    Stefanie Sausenthaler
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstadter Landstr 1, 85764 Neuherberg, Germany
    Public Health Nutr 14:1724-35. 2011
    ..To describe regional differences between eastern and western Germany with regard to food, nutrient and supplement intake in 9-12-year-old children, and analyse its association with parental education and equivalent income...
  20. doi request reprint Common variants in FCER1A influence total serum IgE levels from cord blood up to six years of life
    C M Chen
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 64:1327-32. 2009
    ..In a recent genome wide scan, a functional promoter variant (rs2251746) in the gene encoding the alpha chain of the high affinity receptor for immunoglobulin E (IgE) (FCER1A) was identified as major determinant of serum IgE levels...
  21. ncbi request reprint Social factors, allergen, endotoxin, and dust mass in mattress
    C M Chen
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Indoor Air 17:384-93. 2007
    ..The observed negative association between cat allergen loads and concentrations in mattress and family SES in non-cat owners' homes indicated that community is an important source of cat allergen exposure...
  22. doi request reprint Glutathione-S-transferase P1, early exposure to mould in relation to respiratory and allergic health outcomes in children from six birth cohorts. A meta-analysis
    C G Tischer
    Helmholtz Centre Munich, German Research Centre for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany
    Allergy 68:339-46. 2013
    ..It has been suggested that functional polymorphisms of the GSTP1 gene may influence the risk for allergic disorders through an impaired defence against oxidant injury...
  23. ncbi request reprint Exposure to house dust endotoxin and allergic sensitization in adults
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 59:946-52. 2004
    ..It has been suggested that exposure to elevated levels of endotoxin decreases the risk of allergic sensitization...
  24. doi request reprint Associations between BMI and the FTO gene are age dependent: results from the GINI and LISA birth cohort studies up to age 6 years
    Peter Rzehak
    Institute of Epidemiology, German Research Center for Environmental Health, Helmholtz Zentrum Munchen, Neuherberg, Germany
    Obes Facts 3:173-80. 2010
    ..However, little is known about the longitudinal dynamics of these polymorphisms on body mass index (BMI), overweight, and obesity...
  25. ncbi request reprint Repeated measurements of allergens and endotoxin in settled house dust over a time period of 6 years
    R Topp
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Allergy 33:1659-66. 2003
    ..This singly measured biocontaminant concentration is related to adverse respiratory outcomes such as asthma, wheeze or others...
  26. ncbi request reprint Farming, rural lifestyle and atopy in adults from southern Germany--results from the MONICA/KORA study Augsburg
    B Filipiak
    GSF National Reseach Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Allergy 31:1829-38. 2001
    ..We compared the prevalence of allergic diseases in farmers, and rural, suburban and urban residents in the small geographical area of Augsburg in southern Germany...
  27. pmc Respiratory health and individual estimated exposure to traffic-related air pollutants in a cohort of young children
    V Morgenstern
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Occup Environ Med 64:8-16. 2007
    ....
  28. doi request reprint Prospective association between food sensitization and food allergy: results of the LISA birth cohort study
    E Schnabel
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Allergy 40:450-7. 2010
    ..Food allergy is common, especially in childhood, where 6-8% of children are affected. Identification of early and efficient markers for later development of food allergy is very important...
  29. ncbi request reprint Increasing prevalence of bronchial hyperresponsiveness in three selected areas in East Germany. Bitterfeld Study Group
    C Frye
    , Institut fur Epidemiologie, Neuherberg, Germany
    Eur Respir J 18:451-8. 2001
    ..The present results give indirect evidence, that less respiratory infections may be associated with higher bronchial hyperresponsiveness...
  30. ncbi request reprint Stress-related maternal factors during pregnancy in relation to childhood eczema: results from the LISA Study
    S Sausenthaler
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    J Investig Allergol Clin Immunol 19:481-7. 2009
    ..Stress has been suggested to impact the onset and exacerbation of eczema and other atopic disorders. Whether early exposure to stress-related factors might exert long-term effects remains to be clarified...
  31. ncbi request reprint Early allergic sensitizations and their relevance to atopic diseases in children aged 6 years: results of the GINI study
    I Brockow
    Department of Pediatrics, Technical University of Munich, Munich, Germany
    J Investig Allergol Clin Immunol 19:180-7. 2009
    ..Only a few studies have analyzed the value of early sensitization in predicting the development of atopic disease. The relevance of low immunoglobulin (Ig) E antibody levels in this respect also remains unclear...
  32. ncbi request reprint Atopic disease and its determinants -- a focus on the potential role of childhood infection
    A Resch
    Department of Medical Informatics, Biometry, and Epidemiology, Ludwig Maximilians University, Munich, Germany
    Clin Exp Allergy 34:1184-91. 2004
    ..Atopic diseases develop on a genetic background and are modulated by environmental factors among which some infectious diseases are thought to have a protective influence...
  33. doi request reprint Prenatal and postnatal tobacco smoke exposure and development of insulin resistance in 10 year old children
    Elisabeth Thiering
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Int J Hyg Environ Health 214:361-8. 2011
    ..Positive dose-dependent associations and independent effects of postnatal exposure suggest involvement of environmental tobacco smoke in the risk for development of insulin resistance in children...
  34. ncbi request reprint Predictivity of allergic sensitization (RAST) for the onset of allergic diseases in adults
    Y Schoefer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 63:81-6. 2008
    ..Specific IgE antibodies are often detected without any clinical manifestation of allergies. We aimed to analyse the predictivity of allergic sensitization for incident symptoms of allergic diseases in adults during a 10-year follow-up...
  35. pmc Prenatal and postnatal tobacco exposure and behavioral problems in 10-year-old children: results from the GINI-plus prospective birth cohort study
    Simon Rückinger
    Ludwig Maximilians University Munich, Institute of Social Pediatrics and Adolescent Medicine, Division of Epidemiology, Munich, Germany
    Environ Health Perspect 118:150-4. 2010
    ..Prenatal and postnatal tobacco exposure have been reported to be associated with behavioral problems. However, the magnitude of the association with tobacco exposure at specific periods of exposure is unclear...
  36. ncbi request reprint Health risks of early swimming pool attendance
    Yvonne Schoefer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, 85764 Neuherberg, Germany
    Int J Hyg Environ Health 211:367-73. 2008
    ..In terms of developing atopic diseases there is no verifiable detrimental effect of early swimming...
  37. pmc Influence of FADS polymorphisms on tracking of serum glycerophospholipid fatty acid concentrations and percentage composition in children
    Claudia Glaser
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    PLoS ONE 6:e21933. 2011
    ..Tracking of fatty acid (FA) contribution to plasma or serum lipids over time was shown in children and adults. However, the potential role of FADS gene variants has not been investigated...
  38. ncbi request reprint Predictors of group 5 grass-pollen allergens in settled house dust: comparison between pollination and nonpollination seasons
    B Fahlbusch
    Friedrich-Schiller-University, Institute of Clinical Immunology, Jena, GSF - National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 56:1081-6. 2001
    ..The removal of dust by frequent cleaning reduces the indoor exposure to grass allergens. Such information is essential to train patients in allergen avoidance...
  39. doi request reprint Effect of hydrolysed formula feeding on taste preferences at 10 years. Data from the German Infant Nutritional Intervention Program Plus Study
    Stefanie Sausenthaler
    Helmholtz Zentrum Munchen German Research Center for Environmental Health, Institute of Epidemiology, Germany
    Clin Nutr 29:304-6. 2010
    ..Therefore, the aim of present study was to investigate whether feeding with different kinds of infant formula is associated with the acceptance of infant formula at 10 years of age...
  40. ncbi request reprint Health impacts of second-hand exposure to cat allergen Fel d 1 in infants
    A Heissenhuber
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 58:154-7. 2003
    ..Therefore we restricted our analysis to infants without a cat at home since birth...
  41. ncbi request reprint Levels and predictors of endotoxin in mattress dust samples from East and West German homes
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Indoor Air 14:284-92. 2004
    ..None of these factors explains the difference in infant's mattress dust endotoxin between Leipzig and Munich or could be used as a surrogate for endotoxin...
  42. doi request reprint Growth velocity during infancy and onset of asthma in school-aged children
    C Flexeder
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Neuherberg, Germany
    Allergy 67:257-64. 2012
    ..This study examines the association between peak height and weight velocities during the first 2 years of life and onset of asthma and wheeze up to 10 years of age...
  43. ncbi request reprint Sources and concentrations of indoor nitrogen dioxide in Hamburg (west Germany) and Erfurt (east Germany)
    J Cyrys
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Sci Total Environ 250:51-62. 2000
    ..This variable caused a similar increase in the indoor NO2 levels in each city (43% in Erfurt and 47% in Hamburg). However, outdoor sources of NO2 (motor vehicle traffic) contributed more to indoor NO2 levels in Hamburg than in Erfurt...
  44. pmc Exposure to traffic related air pollutants: self reported traffic intensity versus GIS modelled exposure
    J Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, D 85764 Neuherberg, Germany
    Occup Environ Med 62:517-23. 2005
    ..In epidemiological studies of the potential health effects of traffic related air pollution, self reported traffic intensity is a commonly used, but rarely validated, exposure variable...
  45. ncbi request reprint Vertical and horizontal variability of volatile organic compounds in homes in Eastern Germany
    P Schneider
    GSF Research Center for Environment and Health, Institute of Epidemiology, Munich, Germany
    J Expo Anal Environ Epidemiol 9:282-92. 1999
    ..The indoor BTEX air concentrations were significantly higher than the outdoor concentrations (except benzene). Significant differences in BTEX indoor concentrations between OLD and NEW buildings could not be detected (except toluene)...
  46. ncbi request reprint Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids
    Linda Schaeffer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, 85764 Neuherberg, Germany
    Hum Mol Genet 15:1745-56. 2006
    ..0 x 10(-13)). Carriers of the rare alleles of several SNPs and their respective haplotypes had a lower prevalence of allergic rhinitis and atopic eczema. No association was found for total and specific IgE levels...
  47. ncbi request reprint Factors affecting lead and cadmium levels in house dust in industrial areas of eastern Germany
    I Meyer
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Sci Total Environ 234:25-36. 1999
    ....
  48. ncbi request reprint The distribution in specific IgE and the prevalence of allergic symptoms in 25-64-years old inhabitants of an eastern and a western German city--results from Augsburg and Erfurt
    B Filipiak
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Eur J Epidemiol 17:77-84. 2001
    ..The purpose of this study was to replicate these findings using data from Augsburg, a city from the southern part of West Germany. Furthermore the study population in this analysis was extended to higher age groups...
  49. ncbi request reprint PM25 measurements in ambient aerosol: comparison between Harvard impactor (HI) and the tapered element oscillating microbalance (TEOM) system
    J Cyrys
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Sci Total Environ 278:191-7. 2001
    ..10 x HI - 0.668. Because the measured levels of ammonium nitrate were very low in Erfurt, we concluded that other compounds like semi-volatile organics were responsible for the loss of particulate material at 50 degrees C...
  50. ncbi request reprint Exposure to pets and allergies in children
    Bernd Hölscher
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Pediatr Allergy Immunol 13:334-41. 2002
    ..In conclusion, this study supports the hypothesis of a potential protective mechanism related to dog exposure in early life, especially for children of atopic parents. However, this association was found only for dogs and not for cats...
  51. pmc GIS-based estimation of exposure to particulate matter and NO2 in an urban area: stochastic versus dispersion modeling
    Josef Cyrys
    GSF, National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Environ Health Perspect 113:987-92. 2005
    ..In conclusion, despite different assumptions and procedures used for the stochastic and dispersion modeling, both models yield similar results regarding exposure estimation of the study cohort to traffic-related air pollutants...
  52. ncbi request reprint Daily mortality and particulate matter in different size classes in Erfurt, Germany
    Matthias Stölzel
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    J Expo Sci Environ Epidemiol 17:458-67. 2007
    ..003-1.060. No association between fine particle MC and mortality was found. This study shows that UFP, representing fresh combustion particles, may be an important component of urban air pollution associated with health effects...
  53. doi request reprint Atopic diseases, allergic sensitization, and exposure to traffic-related air pollution in children
    Verena Morgenstern
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, D 85764 Neuherberg, Germany
    Am J Respir Crit Care Med 177:1331-7. 2008
    ..In vitro studies, animal experiments, and human exposure studies have shown how ambient air pollution increases the risk of atopic diseases. However, results derived from observational studies are inconsistent...
  54. ncbi request reprint Weight gain in two adult cohorts in East and West Germany reunification
    K Wimmer
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Cent Eur J Public Health 11:202-8. 2003
    ..If different lifestyle factors after German division contribute to these differences, one might speculate that trends of obesity and overweight in the East and West after German reunification in 1990 would be similar...
  55. ncbi request reprint Trends in food intake in adults from the city of Erfurt before and after the German reunification
    G Winkler
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Ann Nutr Metab 41:283-90. 1997
    ..180 g; 209 vs. 174 g and 62 vs. 53 g. Surprisingly similar changes in eating habits were observed with men and women. The majority of changes could be explained by the improved variety in food supply after the reunification...
  56. ncbi request reprint Inverse social gradient of secondary immune response parameters in children
    G Bolte
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Rev Environ Health 14:135-43. 1999
    ..The aim of our study was to assess the relation between social class, immune parameters, and the prevalence of respiratory infections in children...
  57. ncbi request reprint Parental education and children's respiratory and allergic symptoms in the Pollution and the Young (PATY) study
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 27:95-107. 2006
    ..However, differences remained after adjusting for these variables. Children's health was associated with parental education. The association could not fully be explained by established risk factors...
  58. ncbi request reprint The effect of low-level blood lead on hematologic parameters in children
    B Jacob
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Ingolstadter Landstrasse 1, Neuherberg, D 85758, Germany
    Environ Res 82:150-9. 2000
    ..The reasons for our observation, especially the gender difference, are still uncertain. In conclusion the morphology and function of erythrocytes might be sensitive parameters of low dose lead toxicity...
  59. ncbi request reprint Gas cooking, respiratory health and white blood cell counts in children
    B Hölscher
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Int J Hyg Environ Health 203:29-37. 2000
    ..91-2.10). The strongest effect estimates for chronic inflammation were found for those children likely to have been exposed at higher levels, that is when stoves had no fans, in smaller homes, and for children spending more time indoors...
  60. ncbi request reprint Vaccination against Haemophilus influenzae type b and atopy in east German schoolchildren
    B Laubereau
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Eur J Med Res 7:387-92. 2002
    ..In this paper we investigated the association of Haemophilus influenzae type b (Hib)-vaccination and atopic diseases and allergic sensitisation in children in Eastern Germany...
  61. ncbi request reprint Exposure to pets and atopic dermatitis during the first two years of life. A cohort study
    Angelika Zirngibl
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Pediatr Allergy Immunol 13:394-401. 2002
    ..We assume an association between keeping pets and undefined environmental factor(s) that contribute protectively to the development of atopic dermatitis in early life, presumably by effects on the maturation of the immune system...
  62. ncbi request reprint Long-term exposure to ambient air pollution and cardiopulmonary mortality in women
    Ulrike Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, D 85764 Neuherberg, Germany
    Epidemiology 17:545-51. 2006
    ..We assessed whether long-term exposure to air pollution originating from motorized traffic and industrial sources is associated with total and cause-specific mortality in a cohort of women living in North Rhine-Westphalia, Germany...
  63. pmc Long-term exposure to traffic-related air pollution and insulin resistance in children: results from the GINIplus and LISAplus birth cohorts
    E Thiering
    German Research Center for Environmental Health, Neuherberg, Germany
    Diabetologia 56:1696-704. 2013
    ..We aimed to assess the association between traffic-related air pollution and insulin resistance in children...
  64. doi request reprint [Two German Birth Cohorts: GINIplus and LISAplus]
    J Heinrich
    Deutsches Forschungszentrum für Gesundheit und Umwelt, Institut für Epidemiologie I, Helmholtz Zentrum Munchen, Ingolstadter Landstr 1, 85764, Neuherberg, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 55:864-74. 2012
    ..These data were included in many international projects and consortia for purposes of international comparisons of prevalence and consistency of findings, and to increase the power of the analyses...
  65. doi request reprint Different age-specific incidence and remission rates in pre-school and primary school suggest need for targeted obesity prevention in childhood
    R von Kries
    Institute of Social Paediatrics and Adolescent Medicine, Ludwig Maximilians University, Munich, Germany
    Int J Obes (Lond) 36:505-10. 2012
    ..School entry marks a tremendous change in the children's life style, which might well be relevant for the emergence of overweight. Previous studies suggested a dramatic increase in the prevalence of overweight during this age...
  66. ncbi request reprint Maternal oral contraceptive use and atopic diseases in the offspring
    C Frye
    GSF National Research Center for Environment and Health Institute of Epidemiology, Neuherberg, Germany
    Allergy 58:229-32. 2003
    ..This study examined the association of maternal oral contraceptive (OC) use - before and after birth - and atopic manifestations in the offspring...
  67. doi request reprint Relative weight-related costs of healthcare use by children--results from the two German birth cohorts, GINI-plus and LISA-plus
    Ariane Breitfelder
    Helmholtz Zentrum München German Research Center for Environmental Health Institute of Health Economics and Health Care Management, Munich, Germany
    Econ Hum Biol 9:302-15. 2011
    ..Drawing on these results, differences in healthcare costs between BMI groups are already apparent in children...
  68. ncbi request reprint Indoor and outdoor BTX levels in German cities
    P Schneider
    GSF-National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Sci Total Environ 267:41-51. 2001
    ..The strong and yet undiscovered indoor source for toluene in East Germany might lead to a further increase in the indoor air load in those homes in the East, which undergo renovations which will lead to improved insulation...
  69. ncbi request reprint Margarine consumption and allergy in children
    G Bolte
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Am J Respir Crit Care Med 163:277-9. 2001
    ..Increased intake of certain polyunsaturated fatty acids might further stimulate IgE production in boys...
  70. ncbi request reprint The effect of environmental tobacco smoke exposure on allergic sensitization and allergic rhinitis in adults
    R Topp
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, Neuherberg, Germany
    Indoor Air 15:222-7. 2005
    ..In this work, we assess the association between exposure to environmental tobacco smoke (ETS) at home or at work, and allergic sensitization and allergic rhinitis in 4093 German adults...
  71. ncbi request reprint The association between baseline lung function and bronchial responsiveness to methacholine
    G Wassmer
    GSF, Institut fur Epidemiologie, Neuherberg, Germany
    Eur J Med Res 2:47-54. 1997
    ..Furthermore, our data support the superiority of the dose response slope for the analysis of bronchial responsiveness in epidemiologic surveys...
  72. ncbi request reprint Domestic cat allergen and allergic sensitisation in young children
    Chih Mei Chen
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, D 85764 Neuherberg, Germany
    Int J Hyg Environ Health 211:337-44. 2008
    ..The mixed results may be explained by differences in age and avoidance patterns...
  73. ncbi request reprint House dust endotoxin and allergic sensitization in children
    Ulrike Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Am J Respir Crit Care Med 166:939-44. 2002
    ..The protective effect was strengthened with increasing degree of sensitization. In conclusion, exposure to higher levels of house dust endotoxin is associated with lower prevalence of allergic sensitization in children...
  74. doi request reprint Role of FADS1 and FADS2 polymorphisms in polyunsaturated fatty acid metabolism
    Claudia Glaser
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Munich, Germany
    Metabolism 59:993-9. 2010
    ..We recommend including analyses of FADS1 and FADS2 polymorphism in future cohort and intervention studies addressing biological effects of PUFAs and LC-PUFAs...
  75. doi request reprint Is a child's growth pattern early in life related to serum adipokines at the age of 10 years?
    C Flexeder
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany
    Eur J Clin Nutr 68:25-31. 2014
    ..75 ng/ml; (0.42; 1.09)) and PWV among males (β: 0.45 ng/ml; (0.11; 0.79)).Conclusion:Growth patterns in early life may be associated with leptin levels at age 10 years. ..
  76. doi request reprint Geographical variation and the determinants of domestic endotoxin levels in mattress dust in Europe
    C M Chen
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Indoor Air 22:24-32. 2012
    ..The observed variation needs to be taken into account when evaluating the health effects of endotoxin exposures in international contexts...
  77. doi request reprint Association between domestic mould and mould components, and asthma and allergy in children: a systematic review
    C Tischer
    Institute of Epidemiology, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Ingolstaedter Landstrasse 1, D 85764, Neuherberg, Germany
    Eur Respir J 38:812-24. 2011
    ..In order to disentangle the different effects of overall microbial exposure on children's health, research should focus on specific microbial markers in the home, in combination with new assessment techniques including molecular methods...
  78. ncbi request reprint Arsenic burden among children in industrial areas of eastern Germany
    M J Trepka
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Sci Total Environ 180:95-105. 1996
    ..59 micrograms As/g creatinine; 95% C.I. 4.20-5.02). This suggests that the arsenic contamination in Hettstedt is not substantially increasing the internal burden of arsenic among children above that found in other German children...
  79. ncbi request reprint Food and fatty acid intake and atopic disease in adults
    M A Trak-Fellermeier
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Postfach 11 29, D 85758 Oberschleissheim, Germany
    Eur Respir J 23:575-82. 2004
    ..Dietary factors were mostly not related with prevalence rates of bronchial hyperresponsiveness and atopic eczema either in males or in females...
  80. ncbi request reprint Trends and predictors of overweight and obesity in East German children
    C Frye
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Int J Obes Relat Metab Disord 27:963-9. 2003
    ..Therefore, we analyzed trends in overweight and obesity in East German school children...
  81. ncbi request reprint Atopic eczema in children: another harmful sequel of divorce
    A Bockelbrink
    Department of Medical Statistics and Epidemiology, Technical University Munich, Munich, Germany
    Allergy 61:1397-402. 2006
    ..Only few studies have investigated the association of early stressful life events and atopic eczema (AE) in children...
  82. ncbi request reprint Decline of ambient air pollution and respiratory symptoms in children
    J Heinrich
    Forschungszentrum für Umwelt und Gesundheit, Institut fuer Epidemiologie, and Lehrstuhl für Epidemiologie, Ludwig Maximilians Universitaet München, Neuherberg, Germany
    Am J Respir Crit Care Med 161:1930-6. 2000
    ..76; CI: 0.66 to 0.88) after adjustment for several potential predictors. In conclusion, we found that the prevalence of nonasthmatic respiratory symptoms decreased from the first period to the second period in all three study areas...
  83. pmc Associations between mortality and air pollution in central Europe
    A Peters
    GSF National Research Center for Environment and Health, Neuherberg, Germany
    Environ Health Perspect 108:283-7. 2000
    ....
  84. ncbi request reprint Allergic sensitisation and allergic rhinitis are associated with n-3 polyunsaturated fatty acids in the diet and in red blood cell membranes
    S Hoff
    Unit of Human Nutrition and Cancer Prevention, Technical University of Munich, Munich, Germany
    Eur J Clin Nutr 59:1071-80. 2005
    ..Due to inconsistent results based on dietary intake data, unsaturated fatty acids in red blood cell (RBC) membranes and diet were used to investigate their association with allergic sensitisation and allergic rhinitis...
  85. ncbi request reprint Elemental composition and sources of fine and ultrafine ambient particles in Erfurt, Germany
    J Cyrys
    GSF, National Research Center for Environment and Health, Institute of Epidemiology, Geb 56, O 85764, Neuherberg, Germany
    Sci Total Environ 305:143-56. 2003
    ..Sulfur could be a tracer for coal combustion, however, it was not correlated with any of the quoted elements. Highly correlated elements V and Ni have similar enrichment factors and are considered as tracers for oil combustion...
  86. doi request reprint Fish consumption, allergic sensitisation and allergic diseases in adults
    Markus Schnappinger
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Ann Nutr Metab 54:67-74. 2009
    ..However, it is not clear whether fish intake also has a beneficial effect in adulthood, when allergic diseases are thought to be predominantly manifested...
  87. ncbi request reprint TLR4 gene variants modify endotoxin effects on asthma
    Monika Werner
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
    J Allergy Clin Immunol 112:323-30. 2003
    ..Environmental exposure to endotoxin might have a crucial role in immune maturation and development of asthma...
  88. ncbi request reprint Urban background particulate matter and allergic sensitization in adults of ECRHS II
    Getahun Bero Bedada
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, 85764, Neuherberg, Germany
    Int J Hyg Environ Health 210:691-700. 2007
    ..The aim of this study was to evaluate whether regional urban air pollution may partly explain the large variation in the prevalence of allergic sensitization across cities of the European Community Respiratory Health Survey (ECRHS) II...
  89. pmc Source apportionment of ambient fine particle size distribution using positive matrix factorization in Erfurt, Germany
    Wei Yue
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
    Sci Total Environ 398:133-44. 2008
    ....
  90. ncbi request reprint Serum immunoglobulin level and skin prick test response
    M Wjst
    GSF Forschungszentrum fuer Umwelt und Gesundheit, Institut fuer Epidemiologie, Ingolstaedter Landstrasse 1, Neuherberg, D 85758, Germany
    Eur J Med Res 2:177-81. 1997
    ..Methods: In a population-based study of 2,470 children, 2,188 skin prick tests, and 2,042 blood samples could be analyzed...
  91. ncbi request reprint Allergic sensitization and diet: ecological analysis in selected European cities
    J Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 17:395-402. 2001
    ..59, p = 0.035). These results support the hypothesis that a high intake of monounsaturated fatty acids might promote the development of allergic sensitization...
  92. ncbi request reprint n6/n3 hypothesis and allergies: biologically plausible, but not confirmed
    I Kompauer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, P O Box 1129, D 85758 Neuherberg, Germany
    Eur J Med Res 9:378-82. 2004
    ....
  93. doi request reprint Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism
    Eva Lattka
    Institute of Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Germany
    Curr Opin Lipidol 21:64-9. 2010
    ..The present review summarizes the recent association studies on FADS genotypes and LC-PUFA levels and suggests ideas how FADS genotypes can be integrated in future research...
  94. doi request reprint Association of fatty acids in serum phospholipids with lung function and bronchial hyperresponsiveness in adults
    Iris Kompauer
    Institute of Epidemiology, GSF National Research Center for Environment and Health, P O Box 1129, 85758, Neuherberg, Germany
    Eur J Epidemiol 23:175-90. 2008
    ..The dietary intake of certain fatty acids might have an impact on inflammatory processes in the lung and therefore contribute to the development of lung diseases like asthma or COPD...
  95. doi request reprint Do FADS genotypes enhance our knowledge about fatty acid related phenotypes?
    Eva Lattka
    Institute of Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Germany
    Clin Nutr 29:277-87. 2010
    ....
  96. ncbi request reprint High prevalence of pneumonia in children of a smelter town
    Yvonne Kohlhammer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Int J Occup Environ Health 13:167-74. 2007
    ..Past industrial emissions might still play a decisive role decades after the closing of sources, and pneumonia should be considered a possible acute health burden caused by metal-rich air pollution...
  97. ncbi request reprint Traffic at residential address, respiratory health, and atopy in adults: the National German Health Survey 1998
    Joachim Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, D 85764 Neuherberg, Germany
    Environ Res 98:240-9. 2005
    ..91-1.20)). We conclude that exposure to traffic-related air pollutants increases the risk of nonallergic respiratory symptoms and to a lesser degree the risk of hay fever and allergic sensitization but not the risk of asthma in adults...
  98. ncbi request reprint Seasonal and diurnal variation of PM2.5 apparent particle density in urban air in Augsburg, Germany
    Mike Pitz
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, 85764 Neuherberg, Germany
    Environ Sci Technol 42:5087-93. 2008
    ..rho2.5 has the potential to serve as a crude tracer for chemical composition and atmospheric processing and might play an important role when considering the associations between health effects and ambient particles...
  99. pmc Variants of the FADS1 FADS2 gene cluster, blood levels of polyunsaturated fatty acids and eczema in children within the first 2 years of life
    Peter Rzehak
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    PLoS ONE 5:e13261. 2010
    ..We analyze this genetic-association in two children-cohort-studies. In addition, the association between variants in the FADS-gene-cluster and blood-fatty-acid-composition with eczema was studied...
  100. doi request reprint Short- and long-term effects of feeding hydrolyzed protein infant formulas on growth at < or = 6 y of age: results from the German Infant Nutritional Intervention Study
    Peter Rzehak
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Am J Clin Nutr 89:1846-56. 2009
    ..The short- and long-term effects of feeding with hydrolyzed formulas on growth are uncertain...
  101. doi request reprint Sensitization to contact allergens and bronchial hyper-responsiveness
    Eva Schnabel
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Contact Dermatitis 63:157-63. 2010
    ..Exposure to contact allergens and specific allergic sensitization to them are common, but possible related health effects have been rarely studied...