Ulrich Hengge

Summary

Affiliation: Heinrich Heine University
Country: Germany

Publications

  1. ncbi [Papillomavirus diseases]
    U R Hengge
    Klinik fur Dermatologie, Heinrich Heine Universitat, Moorenstrasse 5, 40225 Dusseldorf, Germany
    Hautarzt 55:841-54. 2004
  2. ncbi Adverse effects of topical glucocorticosteroids
    Ulrich R Hengge
    Department of Dermatology, Heinrich Heine University Duesseldorf, Germany
    J Am Acad Dermatol 54:1-15; quiz 16-8. 2006
  3. pmc Interaction of Adenovirus E1A with the HHV8 Promoter of Latent Genes: E1A Proteins are Able to Activate the HHV-8 LANAp in MV3 Reporter Cells
    Karin Koehler-Hansner
    Department of Internal Medicine Cancer Research, University of Duisburg Essen Medical School, Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Open Virol J 2:61-8. 2008
  4. ncbi [Topical calcineurin inhibitors in dermatology]
    Ulrich Hengge
    Universitatsklinikum Dusseldorf
    Pharm Unserer Zeit 34:314-9. 2005
  5. ncbi [Vulvodynia]
    U R Hengge
    Klinik fur Dermatologie, Heinrich Heine Universitat, Dusseldorf
    Hautarzt 56:556-9. 2005
  6. ncbi [Pigmented lesions of the genital mucosa]
    U R Hengge
    Klinik fur Dermatologie, Heinrich Heine Universitat, Dusseldorf
    Hautarzt 56:540-9. 2005
  7. ncbi [Gene therapy and the skin]
    U R Hengge
    Departement de Dermatologie, Université Heinrich Heine, Duesseldorf, Allemagne
    Ann Dermatol Venereol 132:154-63. 2005
  8. ncbi Progress and prospects of skin gene therapy: a ten year history
    Ulrich R Hengge
    Department of Dermatology, Heinrich Heine University, D 40225 Duesseldorf, Germany
    Clin Dermatol 23:107-14. 2005
  9. ncbi Gene therapy and the skin
    U R Hengge
    Department of Dermatology, University of Dusseldorf, Germany
    Am J Med Genet C Semin Med Genet 131:93-100. 2004
  10. ncbi Gene therapy progress and prospects: the skin--easily accessible, but still far away
    U R Hengge
    Department of Dermatology, Heinrich Heine University, Duesseldorf, Germany
    Gene Ther 13:1555-63. 2006

Collaborators

Detail Information

Publications69

  1. ncbi [Papillomavirus diseases]
    U R Hengge
    Klinik fur Dermatologie, Heinrich Heine Universitat, Moorenstrasse 5, 40225 Dusseldorf, Germany
    Hautarzt 55:841-54. 2004
    ..However, there are enormous differences in price and effort required for treatment, which should be considered when choosing the method...
  2. ncbi Adverse effects of topical glucocorticosteroids
    Ulrich R Hengge
    Department of Dermatology, Heinrich Heine University Duesseldorf, Germany
    J Am Acad Dermatol 54:1-15; quiz 16-8. 2006
    ..The authors provide an updated review of local and systemic adverse effects upon administration of topical corticosteroids, including the latest FDA report on the safety of such steroids in children...
  3. pmc Interaction of Adenovirus E1A with the HHV8 Promoter of Latent Genes: E1A Proteins are Able to Activate the HHV-8 LANAp in MV3 Reporter Cells
    Karin Koehler-Hansner
    Department of Internal Medicine Cancer Research, University of Duisburg Essen Medical School, Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Open Virol J 2:61-8. 2008
    ..These data may have relevance for the management of viral infections in immunocompromised patients. A role for E1A as a therapeutic in this context remains to be defined...
  4. ncbi [Topical calcineurin inhibitors in dermatology]
    Ulrich Hengge
    Universitatsklinikum Dusseldorf
    Pharm Unserer Zeit 34:314-9. 2005
  5. ncbi [Vulvodynia]
    U R Hengge
    Klinik fur Dermatologie, Heinrich Heine Universitat, Dusseldorf
    Hautarzt 56:556-9. 2005
    ..The patients are generally older and dyspareunia is less severe. The prevalence of essential vulvodynia is 1-3%. Various interdisciplinary approaches to these two rather frequent genital diseases are discussed...
  6. ncbi [Pigmented lesions of the genital mucosa]
    U R Hengge
    Klinik fur Dermatologie, Heinrich Heine Universitat, Dusseldorf
    Hautarzt 56:540-9. 2005
    ..An aggressive surgical approach has not been shown to prolong the poor 5-year survival. Cooperation with gynecologists and urologists is essential for the optimal management of such patients...
  7. ncbi [Gene therapy and the skin]
    U R Hengge
    Departement de Dermatologie, Université Heinrich Heine, Duesseldorf, Allemagne
    Ann Dermatol Venereol 132:154-63. 2005
  8. ncbi Progress and prospects of skin gene therapy: a ten year history
    Ulrich R Hengge
    Department of Dermatology, Heinrich Heine University, D 40225 Duesseldorf, Germany
    Clin Dermatol 23:107-14. 2005
    ..Among the first skin diseases patients with junctional epidermolysis bullosa and xeroderma pigmentosum have entered clinical trials...
  9. ncbi Gene therapy and the skin
    U R Hengge
    Department of Dermatology, University of Dusseldorf, Germany
    Am J Med Genet C Semin Med Genet 131:93-100. 2004
    ..Among the first skin diseases, patients with junctional epidermolysis bullosa (JEB) and xeroderma pigmentosum (XP) will enter clinical trials...
  10. ncbi Gene therapy progress and prospects: the skin--easily accessible, but still far away
    U R Hengge
    Department of Dermatology, Heinrich Heine University, Duesseldorf, Germany
    Gene Ther 13:1555-63. 2006
    ..However, the translation into clinical trials has only been partially mastered. The latter and the control of immune responses represent challenges for the research community...
  11. ncbi Multicentre, phase II trial on the safety and efficacy of topical tacrolimus ointment for the treatment of lichen sclerosus
    U R Hengge
    Department of Andrology and Venereology, Philipps University Marburg, Marburg, Germany
    Br J Dermatol 155:1021-8. 2006
    ..Lichen sclerosus is a chronic inflammatory autoimmune disease causing significant sclerosis, atrophy and pruritus. Treatment remains unsatisfactory, with potent corticosteroids being the most effective therapy...
  12. doi [Arthropod bite reactions and pyodermias]
    U R Hengge
    Hautklinik, Heinrich Heine Universitat Dusseldorf, Moorenstrasse 5, 40225 Dusseldorf
    Hautarzt 59:633-41. 2008
    ..For tourists, bacterial infections are often complicating a pruritic bite reaction and scratching. It is important to know the cause of the bite reaction and pyoderma in order to take appropriate therapeutic measures...
  13. doi [Cutaneous leishmaniasis]
    U R Hengge
    Hautklinik, Heinrich Heine Universitat Dusseldorf, Moorenstrasse 5, 40225 Dusseldorf
    Hautarzt 59:627-32. 2008
    ..Both, cutaneous and visceral leishmaniasis, may develop. In contrast, New World leishmaniasis is caused by leishmania found in Central and South America and cause may cutaneous, mucocutaneous and visceral findings...
  14. doi Role of viruses in the development of squamous cell cancer and melanoma
    Ulrich R Hengge
    Department of Dermatology, Heinrich Heine University, Moorenstr 5, D 40225 Dusseldorf, Germany
    Adv Exp Med Biol 624:179-86. 2008
    ..Melanoma-associated retrovirus (MelARV) has been detected in mice and men and was shown to subvert immunosurveillance besides insertional mutagenesis. The state of the art of viral participation in melanomagenesis will be discussed...
  15. doi SMaRT technology enables gene expression repair in skin gene therapy
    Ulrich R Hengge
    Department of Dermatology, Heinrich Heine University, Dusseldorf, Germany
    J Invest Dermatol 128:499-500. 2008
    ..This approach is particularly attractive for skin gene therapy of dominant-negative mutations present in a number of blistering genodermatoses...
  16. ncbi Cost-effectiveness of reduced follow-up in malignant melanoma
    Ulrich R Hengge
    Department of Dermatology, Heinrich Heine University, Dusseldorf, Germany
    J Dtsch Dermatol Ges 5:898-907. 2007
    ..Conclusion: The implementation of a reduced follow-up for melanoma patients seems not only medically justified but also economically required without adversely affecting patient outcome...
  17. ncbi [Topical therapy of squamous cell carcinoma]
    U R Hengge
    Hautklinik, Heinrich Heine Universitat, 40225, Dusseldorf
    Hautarzt 58:412-8. 2007
    ..Topical treatment is particularly attractive for field cancerization involving multiple non-melanoma skin cancers. The dermatologist must identify such patients and lesions and provide the most suited therapy...
  18. ncbi Scabies: a ubiquitous neglected skin disease
    Ulrich R Hengge
    Department of Dermatology, Heinrich Heine University, Dusseldorf, Germany
    Lancet Infect Dis 6:769-79. 2006
    ..Other problems such as post-scabies eczema and reinfestation, and newer treatments such as ivermectin are also discussed...
  19. ncbi [Frequent and rare dermatological diseases in HIV patients]
    U R Hengge
    Hautklinik der Heinrich Heine Universität, Dusseldorf, Germany
    Hautarzt 57:975-84, 986-7. 2006
    ..Moreover, one has to consider HIV if these skin diseases take an atypical or severe course, or if they do not respond properly to appropriate medication. Frequent and rare dermatoses occurring in HIV infection are discussed...
  20. ncbi Topical immunomodulation in dermatology: potential of toll-like receptor agonists
    Ulrich R Hengge
    Department of Dermatology, Heinrich Heine University, Duesseldorf, Germany
    Dermatol Surg 30:1101-12. 2004
    ..Topical immunotherapy using obligate contact sensitizers such as diphencyprone or dinitrochlorobenzene has been used against viral (e.g., common warts) and autoimmune diseases (e.g., alopecia areata)...
  21. ncbi HIV and testosterone therapy
    Ulrich Hengge
    Department of Dermatology, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
    Lancet Infect Dis 3:187-8. 2003
  22. ncbi Double-blind, randomized, placebo-controlled phase III trial of oxymetholone for the treatment of HIV wasting
    Ulrich R Hengge
    STD Unit, Department of Dermatology and Venerology, University of Essen, Germany
    AIDS 17:699-710. 2003
    ....
  23. ncbi Course of HIV disease does not depend on risk group: 7.5-year follow-up in 296 patients
    Ulrich R Hengge
    Department of Dermatology and Venerology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Int J STD AIDS 14:451-7. 2003
    ..The course of HIV disease in a cohort study outside of clinical trials seems not to depend on the mode of transmission...
  24. ncbi Oxymetholone for the treatment of HIV-wasting: a double-blind, randomized, placebo-controlled phase III trial in eugonadal men and women
    Ulrich R Hengge
    Department of Dermatology, University of Dusseldorf, Dusseldorf, Germany
    HIV Clin Trials 4:150-63. 2003
    ....
  25. ncbi HIV-positive men differ in immunologic but not catecholamine response to an acute psychological stressor
    Ulrich R Hengge
    Department of Dermatology, Venerology and Allergology, University of Essen, Hufelandstrasse 55, 45147 Essen, Germany
    Psychoneuroendocrinology 28:643-56. 2003
    ....
  26. ncbi Lyme borreliosis
    Ulrich R Hengge
    Department of Dermatology, Dusseldorf, Germany
    Lancet Infect Dis 3:489-500. 2003
    ..We present evidence-based treatment recommendations for Lyme borreliosis and review the prevention of Lyme borreliosis, including the Lyme vaccines...
  27. ncbi Successful treatment of invasive squamous cell carcinoma using topical imiquimod
    Ulrich R Hengge
    Heinrich Heine University, Duesseldorf, and St Barbara Hospital, Duisburg, Germany
    Arch Dermatol 140:404-6. 2004
  28. ncbi Rapid identification of dysregulated genes in cutaneous malignant melanoma metastases using cDNA technology
    Alireza Mirmohammadsadegh
    Department of Dermatology, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Cells Tissues Organs 177:119-23. 2004
    ..Ultimately, the identification of melanoma-associated genes may provide a potential therapeutic strategy for identifying and targeting malignant melanoma...
  29. ncbi Testosterone replacement for hypogonadism: clinical findings and best practices
    Ulrich R Hengge
    Heinrich Heine University Medical School, Dusseldorf, Germany
    AIDS Read 13:S15-21. 2003
    ..Resistance exercise training also has had favorable effects on body weight and muscle cell mass. In hypogonadal men with AIDS treated with testosterone replacement therapy, researchers noted a positive effect on depression scores...
  30. ncbi Identification and functional characterization of ASK/Dbf4, a novel cell survival gene in cutaneous melanoma with prognostic relevance
    Sandeep Nambiar
    Department of Dermatology, Heinrich Heine University, Moorenstrasse 5, Duesseldorf D 40225, Germany
    Carcinogenesis 28:2501-10. 2007
    ....
  31. ncbi HAX-1, identified by differential display reverse transcription polymerase chain reaction, is overexpressed in lesional psoriasis
    Alireza Mirmohammadsadegh
    Department of Dermatology, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    J Invest Dermatol 120:1045-51. 2003
    ..Antiapoptotic mechanisms are an emerging concept for the understanding of the pathogenesis of this disease possibly leading to clinical applications...
  32. ncbi Epigenetic inactivation of tumor suppressor genes in serum of patients with cutaneous melanoma
    Alessandra Marini
    Department of Dermatology, Heinrich Heine University, Dusseldorf, Germany
    J Invest Dermatol 126:422-31. 2006
    ..This convenient method using a simple blood sample may contribute to classification of melanoma and awaits clinical validation...
  33. ncbi Applications of array technology: melanoma research and diagnosis
    Sandeep Nambiar
    Heine University, Department of Dermatology, Heinrich Heine, Moorenstr 5, 40225 Dusseldorf, Germany
    Expert Rev Mol Diagn 4:549-57. 2004
    ..It also attempts to outline some of the steps needed to develop the key features to be observed in developing diagnostic and prognostic classification systems based upon gene expression profiling...
  34. ncbi Signaling networks in cutaneous melanoma metastasis identified by complementary DNA microarrays
    Sandeep Nambiar
    Department of Dermatology and Institute of Clinical Oncology, Heinrich Heine University, Dusseldorf, Germany
    Arch Dermatol 141:165-73. 2005
    ..Melanoma and human cancers in general undergo a continuous development from benign to malignant states, as most thoroughly documented in the multistep mole-to-melanoma transition...
  35. ncbi ERK1/2 is highly phosphorylated in melanoma metastases and protects melanoma cells from cisplatin-mediated apoptosis
    Alireza Mirmohammadsadegh
    Department of Dermatology, Heinrich Heine University, Dusseldorf, Germany
    J Invest Dermatol 127:2207-15. 2007
    ..Thus, inhibition of ERK1/2 in combination with selected chemotherapeutic agents may hold promise for more effective therapy of melanoma...
  36. doi Transcriptional regulation of ASK/Dbf4 in cutaneous melanoma is dependent on E2F1
    Sandeep Nambiar
    Department of Dermatology, Heinrich Heine University, Duesseldorf, Germany
    Exp Dermatol 17:986-91. 2008
    ..As trans-acting factor binding is fundamental to understand the regulation of gene expression, this study focuses on characterization of the specific transcriptional regulation of ASK/Dbf4 in melanoma...
  37. ncbi Cutaneous melanoma: fishing with chips
    Sandeep Nambiar
    Department of Dermatology, Heinrich Heine University, Duesseldorf, Germany
    Curr Mol Med 8:235-43. 2008
    ..In this review, we focus on various DNA microarray-based studies performed in cutaneous melanoma and summarize our current understanding of the genetics and biology of melanoma progression derived from accumulating genomic information...
  38. ncbi Treosulfan and gemcitabine in metastatic uveal melanoma patients: results of a multicenter feasibility study
    Claudia Pföhler
    Saarland University Hospital, Department of Dermatology, Homburg Saar, Germany
    Anticancer Drugs 14:337-40. 2003
    ..The most common side-effects were leuko- and thrombocytopenia. These preliminary results suggest potential therapeutic benefit of treosulfan+gemcitabine treatment in metastatic uveal melanoma and warrant further controlled studies...
  39. ncbi Molecular cloning and characterization of alternatively spliced mRNA isoforms from psoriatic skin encoding a novel member of the S100 family
    Ronald Wolf
    Department of Dermatology, Heinrich Heine University Dusseldorf, Moorenstrasse 5, 40225 Dusseldorf, Germany
    FASEB J 17:1969-71. 2003
    ..Our data suggest an involvement of the novel S100A15 in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases...
  40. ncbi Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2
    Denis Selimovic
    Laboratory for Molecular Tumour Therapy, Department of Dermatology, University Hospital of Duesseldorf, Duesseldorf, Germany
    Cell Signal 20:311-22. 2008
    ..Our data provide evidence that taxol-induced mitochondrial stress occurs through the activation of both JNK and p38 pathways, and suggest a novel role for UCP2 in the modulation of taxol-induced apoptosis of melanoma cells...
  41. ncbi 31-year-old injection drug user with massive skin necrosis and shock
    Ulrich R Hengge
    Department of Dermatology, University of Essen, Germany
    Dermatology 206:169-71. 2003
    ..Following surgical treatment and antibiotic treatment, the patient was cured and is currently well...
  42. ncbi Epigenetic silencing of the PTEN gene in melanoma
    Alireza Mirmohammadsadegh
    Department of Dermatology, Heinrich Heine University, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    Cancer Res 66:6546-52. 2006
    ..In summary, epigenetic PTEN silencing seems to be a relevant mechanism of inactivating this tumor suppressor gene in melanoma that may promote melanoma development by derepression of the AKT pathway...
  43. ncbi Topical application of plasmid DNA to mouse and human skin
    Nuschin Meykadeh
    Department of Dermatology, Heinrich Heine University of Dusseldorf, Moorenstr 5, 40225, Dusseldorf, Germany
    J Mol Med (Berl) 83:897-903. 2005
    ..This spray method may thus be useful for DNA vaccination. To increase its attractiveness for skin gene therapy, the improvement of topical formulations with enhanced DNA absorption is desirable...
  44. ncbi Opioid receptors on white blood cells: effect of HIV infection and methadone treatment
    Martina Beck
    Department of Dermatology, Venerology and Allergology, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Pain 98:187-94. 2002
    ..The quantification of OR on immune cells may help to elucidate the effects of opioid analogues in health and drug addiction...
  45. ncbi Lymphocytes proliferate in blood and lymph nodes following interleukin-2 therapy in addition to highly active antiretroviral therapy
    Ulrich R Hengge
    Department of Dermatology, Venerology and Allergology, University of Essen, Essen, Germany
    AIDS 16:151-60. 2002
    ..Substantial redistribution of lymphocytes occurs upon the initiation of highly active antiretroviral therapy (HAART) and immune-based HIV therapies...
  46. ncbi Induction of acute phase response genes in keratinocytes following exposure to oligodeoxynucleotides
    Alireza Mirmohammadsadegh
    Department of Dermatology, Venerology and Allergology, University of Essen, Hufelandstrasse 55, 45122 Essen, Essen, Germany
    J Mol Med (Berl) 80:377-83. 2002
    ..Therefore it is tempting to speculate that upon internalization ODN bind to an intracellular receptor (e.g., Toll-like receptor 9) which mediates signaling...
  47. doi Role of erythropoietin receptor expression in malignant melanoma
    Alireza Mirmohammadsadegh
    Department of Dermatology, Heinrich Heine University, Duesseldorf, Germany
    J Invest Dermatol 130:201-10. 2010
    ....
  48. ncbi Update on Kaposi's sarcoma and other HHV8 associated diseases. Part 1: epidemiology, environmental predispositions, clinical manifestations, and therapy
    Ulrich R Hengge
    Department of Dermatology, Venereology and Allergology, University of Essen, Germany
    Lancet Infect Dis 2:281-92. 2002
    ..Part 2, to be published next month, will summarise recent insights in the pathogenesis of KS and will discuss other HHV8-related diseases such as Castleman's disease and primary effusion lymphoma...
  49. ncbi Squamous cell cancer and human papillomavirus infection in oral lichen planus: case report and literature review
    Alessandra Marini
    Department of Dermatology, Heirich Heine University, Dusseldorf, Germany
    Dermatol Surg 33:756-60. 2007
  50. ncbi STAT5 phosphorylation in malignant melanoma is important for survival and is mediated through SRC and JAK1 kinases
    Alireza Mirmohammadsadegh
    Department of Dermatology, Heinrich Heine University, Dusseldorf, Germany
    J Invest Dermatol 126:2272-80. 2006
    ..Our study identifies phosphorylated STAT5 in melanoma and shows regulation through rEGF; STAT5 may thus act as a survival factor for growth of human melanoma and may represent a potential target for molecular therapy...
  51. ncbi Update on Kaposi's sarcoma and other HHV8 associated diseases. Part 2: pathogenesis, Castleman's disease, and pleural effusion lymphoma
    Ulrich R Hengge
    Department of Dermatology, Venerology, and Allergology, University of Essen, Germany
    Lancet Infect Dis 2:344-52. 2002
    ..Pleural effusion lymphoma has an intermediate immunophenotype lacking B or T lymphocyte antigens and also belongs to the diseases associated with HHV8...
  52. ncbi [Acute localized exanthematous pustulosis (ALEP)]
    Birte Prange
    Hautklinik, Heinrich Heine Universitat Dusseldorf, Germany
    J Dtsch Dermatol Ges 3:210-2. 2005
    ..We report on a female patient who according to the criteria of AGEP was diagnosed as having acute localized exanthematic pustulosis (ALEP) on the face...
  53. ncbi Protein microarrays for the detection of biomarkers in head and neck squamous cell carcinomas
    Anette Weber
    Department of ENT, University of Leipzig, 04103 Leipzig, Germany
    Hum Pathol 38:228-38. 2007
    ..These data indicate that our protein arrays provide protein information in a systematic, reproducible, and also high-throughput fashion...
  54. ncbi Suicide gene therapy of sarcoma cell lines using recombinant adeno-associated virus 2 vectors
    Marlon R Veldwijk
    Department of Radiation Oncology, Universitatsklinikum Mannheim, University of Heidelberg, Theodor Kutzer Ufer 1 3, D 68135, Germany
    Cancer Gene Ther 11:577-84. 2004
    ..These data hold promise for further development of rAAV-2-based suicide gene therapy of sarcomas...
  55. ncbi Imiquimod to treat different cancers of the epidermis
    Jan Eklind
    Department of Dermatology, Huddinge University Hospital, Stockholm, Sweden
    Dermatol Surg 29:890-6; discussion 896. 2003
    ....
  56. ncbi Molecular epidemiology of Kaposi's sarcoma herpesvirus (KSHV) in Cuban and German patients with Kaposi's sarcoma (KS) and asymptomatic sexual contacts
    Vivian Kouri
    Instituto de Medicina Tropical Pedro Kouri, Ciudad de La Habana, Cuba
    Virology 337:297-303. 2005
    ..The unique ethnic background of the Cuban population may explain the variety of different KSHV strains...
  57. ncbi Nearly identical strains of human herpesvirus 8 in couples discordant for Kaposi's sarcoma
    Vivian Kouri
    Instituto de Medicina Tropical Pedro Kouri, Ciudad de La Habana, Cuba
    AIDS 21:765-8. 2007
    ..By quantitative real-time polymerase chain reaction and HHV-8 genotyping we provide strong evidence for the sexual transmission of HHV-8 in this unique cohort...
  58. ncbi Imiquimod and squamous cell cancer
    Ulrich R Hengge
    Arch Dermatol 141:787-8. 2005
  59. ncbi Topical imiquimod to treat recurrent breast cancer
    Ulrich R Hengge
    Breast Cancer Res Treat 94:93-4. 2005
  60. ncbi Development and optimization of a real-time quantitative PCR-based method for the titration of AAV-2 vector stocks
    Marlon R Veldwijk
    German Cancer Research Center, Im Neuenheimer Feld 280 D 69120, Heidelberg, Germany
    Mol Ther 6:272-8. 2002
    ..The highly standardized titration by RQPCR described here will be especially advantageous for groups working on AAV-based gene therapy in a good manufacturing practice setting...
  61. ncbi Calcineurin antagonists in vulvar lichen sclerosus
    Hans J Strittmatter
    Department of Gynecology and Obstetrics, Alfried Krupp Hospital, Alfried Krupp Str 61, 45131 Essen, Germany
    Arch Gynecol Obstet 274:266-70. 2006
    ..An interdisciplinary management and a continued care of patients with LS will improve the clinical manifestations and quality of life...
  62. ncbi BRAF gene mutations are rare events in gastroenteropancreatic neuroendocrine tumors
    Andrea Tannapfel
    Institute of Pathology, University of Leipzig, Germany
    Am J Clin Pathol 123:256-60. 2005
    ..Nevertheless, activation of the RAF/mitogen-activated protein kinase pathway might have a causative role in the development of neuroendocrine tumors, independent of BRAF or k-ras-2 mutation...
  63. ncbi Molecular epidemiology and KSHV K1 subtypes in a Cuban AIDS-Kaposi's sarcoma population
    Vivian Kouri
    Department of Virology, Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba
    AIDS 19:984-7. 2005
    ..The molecular epidemiology of the KSHV subtypes seems to reflect the unique mixed ethnic background of the Cuban population...
  64. ncbi Clinical value of adjunctive interleukin-2: clarifications and corrections
    Ulrich R Hengge
    J Infect Dis 187:340; author reply 340-1. 2003
  65. ncbi Overexpression of acid sphingomyelinase sensitizes glioma cells to chemotherapy
    Georgios Grammatikos
    Department of Molecular Biology, University of Duisburg Essen, Essen, Germany
    Antioxid Redox Signal 9:1449-56. 2007
    ....
  66. ncbi Severe serum sickness following pneumococcal vaccination in an AIDS patient
    Ulrich R Hengge
    Int J STD AIDS 17:210-1. 2006
  67. ncbi Allele loss and epigenetic inactivation of 3p21.3 in malignant liver tumors
    Iris Tischoff
    Institute of Pathology, University of Leipzig, Leipzig, Germany
    Int J Cancer 115:684-9. 2005
    ..In conclusion, our data indicate that 2-hit gene silencing of SEMA3B through epigenetic changes and allele loss is a common and important event in the carcinogenesis of malignant liver tumors...
  68. ncbi A 32-year-old man with relapsing-progressive brainstem symptoms
    Helmar C Lehmann
    Department of Neurology, and Institute of Diagnostic Radiology Heinrich Heine University, Duesseldorf, Germany
    Lancet Neurol 5:97-102. 2006
  69. ncbi Human Papillomavirus infections in Cuban women with cervical intraepithelial neoplasia
    Yudira Soto
    Virology Department, Pedro Kouri Tropical Medicine Institute, Havana City, Cuba
    Sex Transm Dis 34:974-6. 2007