J J Heinisch

Summary

Affiliation: Heinrich Heine University
Country: Germany

Publications

  1. ncbi request reprint The protein kinase C-mediated MAP kinase pathway involved in the maintenance of cellular integrity in Saccharomyces cerevisiae
    J J Heinisch
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Universitatsstr 1, Geb 26 12, D 40225 Dusseldorf, Germany
    Mol Microbiol 32:671-80. 1999
  2. ncbi request reprint Lrg1p functions as a putative GTPase-activating protein in the Pkc1p-mediated cell integrity pathway in Saccharomyces cerevisiae
    A Lorberg
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Geb 26 12, 40225 Dusseldorf, Germany
    Mol Genet Genomics 266:514-26. 2001
  3. ncbi request reprint The PH domain of the yeast GEF Rom2p serves an essential function in vivo
    A Lorberg
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Universitatsstr 1, Geb 26 12, D 40225 Dusseldorf, Germany
    Mol Genet Genomics 266:505-13. 2001
  4. ncbi request reprint Characterization of KLBCK1, encoding a MAP kinase kinase kinase of Kluyveromyces lactis
    J J Jacoby
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Universitätsstr 1 Geb 26 12, Dusseldorf, D 40225, FRG
    J Mol Biol 288:337-52. 1999
  5. ncbi request reprint A screen for upstream components of the yeast protein kinase C signal transduction pathway identifies the product of the SLG1 gene
    J J Jacoby
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Germany
    Mol Gen Genet 258:148-55. 1998
  6. ncbi request reprint Investigation of two yeast genes encoding putative isoenzymes of phosphoglycerate mutase
    J J Heinisch
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Germany
    Yeast 14:203-13. 1998
  7. pmc Characterization of a glucose-repressed pyruvate kinase (Pyk2p) in Saccharomyces cerevisiae that is catalytically insensitive to fructose-1,6-bisphosphate
    E Boles
    Institut fur Mikrobiologie, Heinrich Heine Universitat, Dusseldorf, Germany
    J Bacteriol 179:2987-93. 1997
  8. ncbi request reprint Domain shuffling as a tool for investigation of protein function: substitution of the cysteine-rich region of Raf kinase and PKC eta for that of yeast Pkc1p
    H P Schmitz
    , , , , D 40225, Germany
    J Mol Biol 311:1-7. 2001
  9. ncbi request reprint PFK2, ISP42, ERG2 and RAD14 are located on the right arm of chromosome XIII
    J J Heinisch
    , , Germany
    Yeast 9:1103-5. 1993
  10. ncbi request reprint Functional complementation of yeast phosphofructokinase mutants by the non-allosteric enzyme from Dictyostelium discoideum
    A M Estevez
    Departamento de Bioquímica de la UAM, Facultad de Medicina, Universidad Autonoma, Madrid, Spain
    FEBS Lett 374:100-4. 1995

Collaborators

  • S Muller
  • E Boles
  • J J Jacoby
  • H P Schmitz
  • A Lorberg
  • C Block
  • A M Estevez
  • L Kirchrath
  • U Gengenbacher
  • S M Nilius
  • J J Aragón

Detail Information

Publications10

  1. ncbi request reprint The protein kinase C-mediated MAP kinase pathway involved in the maintenance of cellular integrity in Saccharomyces cerevisiae
    J J Heinisch
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Universitatsstr 1, Geb 26 12, D 40225 Dusseldorf, Germany
    Mol Microbiol 32:671-80. 1999
    ....
  2. ncbi request reprint Lrg1p functions as a putative GTPase-activating protein in the Pkc1p-mediated cell integrity pathway in Saccharomyces cerevisiae
    A Lorberg
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Geb 26 12, 40225 Dusseldorf, Germany
    Mol Genet Genomics 266:514-26. 2001
    ..We therefore suggest that Lrg1p acts as a negative regulator of the Pkc1p pathway in conjunction with its known homologue Sac7p...
  3. ncbi request reprint The PH domain of the yeast GEF Rom2p serves an essential function in vivo
    A Lorberg
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Universitatsstr 1, Geb 26 12, D 40225 Dusseldorf, Germany
    Mol Genet Genomics 266:505-13. 2001
    ....
  4. ncbi request reprint Characterization of KLBCK1, encoding a MAP kinase kinase kinase of Kluyveromyces lactis
    J J Jacoby
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Universitätsstr 1 Geb 26 12, Dusseldorf, D 40225, FRG
    J Mol Biol 288:337-52. 1999
    ..Thus, despite the functional conservation in this component of the MAP kinase pathway in both yeast, cellular integrity in K. lactis may depend at least in part on different signalling mechanisms when compared with S. cerevisiae...
  5. ncbi request reprint A screen for upstream components of the yeast protein kinase C signal transduction pathway identifies the product of the SLG1 gene
    J J Jacoby
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Germany
    Mol Gen Genet 258:148-55. 1998
    ..In addition, a SLG1-lacZ reporter construct shows higher expression in the presence of caffeine or magnesium chloride in a wild-type diploid background...
  6. ncbi request reprint Investigation of two yeast genes encoding putative isoenzymes of phosphoglycerate mutase
    J J Heinisch
    Institut fur Mikrobiologie, Heinrich Heine Universitat Dusseldorf, Germany
    Yeast 14:203-13. 1998
    ..We conclude that both genes evolved from duplication events and that they probably constitute non-functional homologues in yeast...
  7. pmc Characterization of a glucose-repressed pyruvate kinase (Pyk2p) in Saccharomyces cerevisiae that is catalytically insensitive to fructose-1,6-bisphosphate
    E Boles
    Institut fur Mikrobiologie, Heinrich Heine Universitat, Dusseldorf, Germany
    J Bacteriol 179:2987-93. 1997
    ..The results indicate that the PYK2-encoded pyruvate kinase may be used under conditions of very low glycolytic flux...
  8. ncbi request reprint Domain shuffling as a tool for investigation of protein function: substitution of the cysteine-rich region of Raf kinase and PKC eta for that of yeast Pkc1p
    H P Schmitz
    , , , , D 40225, Germany
    J Mol Biol 311:1-7. 2001
    ..We interpret these data as further evidence that interaction with a small GTPase is the main regulatory function of the C1 domain in yeast...
  9. ncbi request reprint PFK2, ISP42, ERG2 and RAD14 are located on the right arm of chromosome XIII
    J J Heinisch
    , , Germany
    Yeast 9:1103-5. 1993
    ..Four genes were shown to reside on this fragment, namely PFK2, ISP42, ERG2 and RAD14. PFK2 was mapped previously to the right arm of chromosome XIII, locating the latter three genes to the same chromosome...
  10. ncbi request reprint Functional complementation of yeast phosphofructokinase mutants by the non-allosteric enzyme from Dictyostelium discoideum
    A M Estevez
    Departamento de Bioquímica de la UAM, Facultad de Medicina, Universidad Autonoma, Madrid, Spain
    FEBS Lett 374:100-4. 1995
    ..discoideum PFK. It exhibited the same subunit size, quaternary structure and kinetic parameters than those of the wild-type enzyme, and was also devoid of specific regulatory properties...