Research Topics
| W GaebelSummaryAffiliation: Heinrich Heine University Country: Germany Publications
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Publications
Schizophrenia practice guidelines: international survey and comparisonWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University Dusseldorf, Germany
Br J Psychiatry 187:248-55. 2005..Schizophrenia guidelines differ considerably in methodology and content...
Psychotic disorders in ICD-11Wolfgang Gaebel
Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany Electronic address
Asian J Psychiatr 6:263-5. 2013..The proposals for ICD-11 are compared with those for the corresponding DSM-5 chapter...
Classifying psychosis--challenges and opportunitiesWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany
Int Rev Psychiatry 24:538-48. 2012....
EPA guidance on the quality of mental health servicesW Gaebel
Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany
Eur Psychiatry 27:87-113. 2012..Further pan-European research will need to show whether the implementation of this guidance will lead to improved quality of mental healthcare, and may help to develop useful country-specific cutoffs for the suggested quality indicators...
Psychiatry in Germany 2012Wolfgang Gaebel
Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University Dusseldorf, Germany
Int Rev Psychiatry 24:371-8. 2012..Mental healthcare research will take centre stage in addressing these challenges...
European guidance: a project of the European Psychiatric AssociationW Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University, Duesseldorf, Germany
Eur Psychiatry 27:65-7. 2012..It is in this scope that a European Psychiatry Association (EPA) has developed its own program, the European Guidance Project. The present special issue presents six topics out of these series of guidance documents...
The DGPPN research project on mental healthcare utilization in Germany: inpatient and outpatient treatment of persons with depression by different disciplinesWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, LVR Klinikum Düsseldorf, Bergische Landstr 2, 40629 Düsseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 262:S51-5. 2012..Specialists for psychosomatic medicine and psychological psychotherapists predominantly treated cases of mild and moderate depression, whereas severe cases were mostly cared for by psychiatrists or psychiatric departments...
Status of Psychotic Disorders in ICD-11Wolfgang Gaebel
To whom correspondence to be addressed LVR Klinikum Düsseldorf, Bergische Landstr 2, D 40629 Düsseldorf, Germany tel 49 211 922 2001, fax 49 211 922 2020, E mail
Schizophr Bull 38:895-8. 2012....
Needs-oriented discharge planning and monitoring for high utilisers of psychiatric services (NODPAM): design and methodsBernd Puschner
Department of Psychiatry II, Ulm University, BKH Günzburg, Ludwig Heilmeyer Str 2, 89312 Günzburg, Germany
BMC Health Serv Res 8:152. 2008..Attempts to reduce high utilisation of psychiatric inpatient care by targeting the critical time of hospital discharge have been rare...
Integrative etiopathogenetic models of psychotic disorders: methods, evidence and conceptsWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, LVR Klinikum Düsseldorf, Bergische Landstrasse 2, D 40629 Düsseldorf, Germany
Schizophr Bull 37:S5-12. 2011....
Measuring the stigma of psychiatry and psychiatrists: development of a questionnaireWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Duesseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 261:S119-23. 2011..It is available in several languages (Arab, English, German, Japanese, Polish, and Spanish) and can easily be adapted for utilization in other medical specialties...
Schizophrenia guidelines across the world: a selective review and comparisonWolfgang Gaebel
Department of Psychiatry and Psychotherapy, LVR Klinikum Düsseldorf, Heinrich Heine University Dusseldorf, Germany
Int Rev Psychiatry 23:379-87. 2011..Nevertheless, core guideline recommendations should be adapted to regional conditions using available tools for adaptation...
Course typologies, treatment principles, and research conceptsW Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University Dusseldorf, Bergische Landstrasse 2, 40629 Düsseldorf, Germany
Pharmacopsychiatry 37:S90-7. 2004..Finally, further research recommendations are given. Future research should elaborate on the neurobiological characteristics of course and outcome in methodologically adequate prospective interventional long-term studies...
Facial expressivity in the course of schizophrenia and depressionWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University Duesseldorf Rheinische Kliniken Duesseldorf, Bergische Landstrasse 2, 40629 Duesseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 254:335-42. 2004....
Atypical and typical neuroleptics in acute schizophrenia and related delusional disorders. Drug choice, switching and outcome under naturalistic treatment conditionsWolfgang Gaebel
Department of Psychiatry, Heinrich Heine University Dusseldorf, Bergische Landstrasse 2, 40629 Düsseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 253:175-84. 2003..Reasons and implications of these findings considering the methodological limitations are discussed...
Evaluation of the German WPA "program against stigma and discrimination because of schizophrenia--Open the Doors": results from representative telephone surveys before and after three years of antistigma interventionsWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University Dusseldorf, Rhineland State Clinics Düsseldorf, Bergische Landstrasse 2, D 40629 Düsseldorf, Germany
Schizophr Res 98:184-93. 2008..Several measures to tackle the stigma in certain target populations have been proven successful, but the effectiveness of the program on the general population level has not yet been examined...
Pharmacological long-term treatment strategies in first episode schizophrenia--study design and preliminary results of an ongoing RCT within the German Research Network on SchizophreniaWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University Dusseldorf, Rhineland State Clinics Düsseldorf, Bergische Landstrasse 2, 40629 Duesseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 254:129-40. 2004..In conclusion, treatment in first episode schizophrenia is effective under both (further on blinded) neuroleptics; however these patients are at high risk for treatment drop-out. This emphasizes the need for a special support program...
Modern treatment concepts in schizophreniaW Gaebel
Department of Psychiatry, Heinrich Heine University Rhineland State Clinics Düsseldorf, Dusseldorf, Germany
Pharmacopsychiatry 36:S168-75. 2003..Additionally, based on current research programmes, future treatment developments are presented...
First vs multiple episode schizophrenia: two-year outcome of intermittent and maintenance medication strategiesWolfgang Gaebel
Department of Psychiatry, Heinrich Heine University Dusseldorf, Bergische Landstr 2, 40629 Düsseldorf, Germany
Schizophr Res 53:145-59. 2002..In FE patients, prodrome-based intermittent intervention seems to be equivalent or even better with respect to compliance and dosage applied...
[Guideline-oriented patient information on depression--an example contributing to the provision of sound professional health information for patients and relatives]Wolfgang Gaebel
Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Heinrich Heine Universitat, Rheinische Kliniken Düsseldorf
Z Arztl Fortbild Qualitatssich 97:80-2. 2003....
Drug attitude as predictor for effectiveness in first-episode schizophrenia: Results of an open randomized trial (EUFEST)Wolfgang Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University Dusseldorf, Rhineland State Clinics Düsseldorf, Germany
Eur Neuropsychopharmacol 20:310-6. 2010..DAI scores could also serve as an (differential) indicator for the need of enhanced treatment monitoring. These findings have to be validated in other (first-episode) samples...
Future classification of psychotic disordersWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 259:S213-8. 2009..Given the rapid progress in these fields, regular updates of the classification criteria at shorter intervals than in the past may become necessary...
Mental health quality, outcome measurement, and improvement in GermanyWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University, Dusseldorf, Germany
Curr Opin Psychiatry 22:636-42. 2009..This review describes the most recent results of quality assurance programs from Germany as identified by a systematic literature search covering the time span 1 January 2008 until 1 June 2009...
[Long-term medication in schizophrenic psychoses]W Gaebel
Psychiatrische Klinik, Heinrich Heine Universitat Dusseldorf
Fortschr Neurol Psychiatr 68:S26-31. 2000..Treatment guidelines developed mainly by the scientific medical societies can help the practitioner in making the right decisions...
The DSM-V initiative "deconstructing psychosis" in the context of Kraepelin's concept on nosologyWolfgang Gaebel
Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Heinrich Heine Universitat, Rheinische Kliniken Düsseldorf, Bergische Landstr 2, 40629, Dusseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 258:41-7. 2008....
Maintenance treatment with risperidone or low-dose haloperidol in first-episode schizophrenia: 1-year results of a randomized controlled trial within the German Research Network on SchizophreniaWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University of Dusseldorf, Rhineland State Clinics Düsseldorf, Dusseldorf, Germany
J Clin Psychiatry 68:1763-74. 2007..Accordingly, the hypothesis of whether 1-year relapse rate in first-episode schizophrenia under maintenance treatment with risperidone is lower compared to haloperidol in low dose was tested...
Revisiting the relapse predictive validity of prodromal symptoms in schizophreniaWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University, Dusseldorf, Germany
Schizophr Res 95:19-29. 2007..yielded other relevant 'early signs'. It is concluded that the relapse predictive validity of prodromal symptoms has to be enhanced e.g. by supplement of other clinical parameters with predictive potential or by closer monitoring...
Relapse prevention in first-episode schizophrenia--maintenance vs intermittent drug treatment with prodrome-based early intervention: results of a randomized controlled trial within the German Research Network on SchizophreniaWolfgang Gaebel
Department of Psychiatry and Psychotherapy, Heinrich Heine University, Dusseldorf, Rhineland State Clinics Düsseldorf, Bergische Landstraße 2, D 40629 Düsseldorf, Germany
J Clin Psychiatry 72:205-18. 2011..The current study was therefore designed to compare prospectively the relapse preventive efficacy of further maintenance treatment and targeted intermittent treatment in patients with ICD-10-diagnosed first-episode schizophrenia...
A critical analysis and discussion of the appropriateness of the schizophrenia consensus remission criteria in clinical pharmaceutical trialsR Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
Pharmacopsychiatry 43:245-51. 2010..The aim of this paper is to apply the proposed consensus remission criteria to an acutely ill inpatient sample at admission and evaluate their adaptability in this patient population and pharmaceutical trials...
Outcome of suicidal patients with schizophrenia: results from a naturalistic studyR Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
Acta Psychiatr Scand 121:359-70. 2010..Purpose was to assess suicidality before and at the time of admission in patients with schizophrenia and compare outcome differences...
Response and remission of subjective well-being in patients suffering from schizophrenia spectrum disordersR Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336 Munich, Germany
Eur Psychiatry 26:284-92. 2011..Purpose of this study was to assess subjective well-being in schizophrenia inpatients and to find variables predictive for response and remission of subjective well-being...
Evaluating depressive symptoms and their impact on outcome in schizophrenia applying the Calgary Depression ScaleR Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
Acta Psychiatr Scand 123:228-38. 2011..To examine depressive symptoms, their course during treatment, and influence on outcome...
Insight in schizophrenia-course and predictors during the acute treatment phase of patients suffering from a schizophrenia spectrum disorderR Schennach
Department of Psychiatry, Ludwig Maximilians University, Nussbaumstraße 7, 80336 Munich, Germany
Eur Psychiatry 27:625-33. 2012..To analyse insight of illness during the course of inpatient treatment, and to identify influencing factors and predictors of insight...
Preventing progression to first-episode psychosis in early initial prodromal statesA Bechdolf
Department of Psychiatry and Psychotherapy, University of Cologne, Germany
Br J Psychiatry 200:22-9. 2012....
Early improvement as a predictor of remission and response in schizophrenia: Results from a naturalistic studyM Jager
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
Eur Psychiatry 24:501-6. 2009..To examine the predictive validity of early improvement in a naturalistic sample of inpatients and to identify the criterion that best defines early improvement...
The validity of self-rated psychotic symptoms in depressed inpatientsF Seemüller
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336 Munich, Germany
Eur Psychiatry 27:547-52. 2012..Self-ratings of psychotic experiences might be biased by depressive symptoms...
Time course of antipsychotic treatment response in schizophrenia: results from a naturalistic study in 280 patientsM Jager
Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
Schizophr Res 118:183-8. 2010..To describe the course of positive and negative symptoms during inpatient treatment and examine remission and response rates under routine clinical care conditions...
Schizophrenics with small P300: a subgroup with a neurodevelopmental disturbance and a high risk for tardive dyskinesia?U Hegerl
Department of Psychiatry, Ludwig Maximilians Universitat Munchen, Germany
Acta Psychiatr Scand 91:120-5. 1995..These findings indicate that schizophrenic patients with a reduced P3 have a higher risk of developing tardive dyskinesia and correspond clinically to a schizophrenic subgroup with a supposedly neurodevelopmental disturbance...
Guideline adherence in medication management of psychotic disorders: an observational multisite hospital studyS Weinmann
Department of Psychiatry and Psychotherapy, Heinrich Heine University, Duesseldorf, Germany. stefan.weinmann.de
Acta Psychiatr Scand 112:18-25. 2005..23-4.23) had a higher likelihood of not being treated according to guidelines. CONCLUSION: Individuals with chronic and thought-disordered psychosis may be at a higher risk of receiving medication care not supported by guidelines...
Neurophysiological correlates of the recognition of facial expressions of emotion as revealed by magnetoencephalographyM Streit
Department of Psychiatry, University of Dusseldorf, Germany
Brain Res Cogn Brain Res 7:481-91. 1999..These findings support the assumption that MEG is able to specifically identify the activation pattern of the brain when recognition of the emotional expression of a face is performed...
Facial affect recognition in the course of schizophreniaW Wolwer
Department of Psychiatry, Heinrich Heine University Dusseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 246:165-70. 1996..This suggests that deficits in facial affect recognition in schizophrenia reflect a trait-like, rather than a state-dependent, characteristic...
Electrophysiological correlates of emotional and structural face processing in humansM Streit
Department of Psychiatry, University of Dusseldorf, Germany
Neurosci Lett 278:13-6. 2000..These data point to the assumption that decoding of facial expressions starts early in the brain and might be processed separately from basic stages of face perception...
Out-patient behaviour therapy in alcoholism: impact of personality disorders and cognitive impairmentsW Wolwer
Department of Psychiatry, Heinrich Heine University, Duesseldorf, Germany
Acta Psychiatr Scand 103:30-7. 2001..We investigated whether alcoholic patients with comorbid personality disorders and those with cognitive impairments would benefit in a different way from different behaviour therapy strategies...
[Outpatient behavioural treatment in alcoholism: alcohol consumption and sociodemographic factors]W Burtscheidt
Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Heinrich Heine Universitat, Dusseldorf
Fortschr Neurol Psychiatr 69:526-31. 2001..Statistically significant differences between the 2 behavioural therapy strategies could be established in neither respect...
[Changes in the public's social distance toward individuals with schizophrenia in six German cities. Results of representative pre- and postinterventional telephone surveys from 2001 to 2004]A Baumann
Klinik und Poliklinik für Psychiatrie und Psychotherapie der Heinrich Heine Universität, Rheinische Kliniken Düsseldorf, 40629 Düsseldorf
Nervenarzt 78:787-8, 790-5. 2007..So far only single interventions in specific target groups have been evaluated but not their effectiveness in the general population...
Improving outpatient treatment in schizophrenia: effects of computerized guideline implementation--results of a multicenter-study within the German research network on schizophreniaB Janssen
Department of Psychiatry and Psychotherapy, Heinrich Heine University Duesseldorf, Bergische Landstrasse 2, 40629, Duesseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 260:51-7. 2010..The findings suggest that decision-support systems, despite their limitations, can be used to enhance treatment outcome in schizophrenia outpatient care...
Reduced subjective quality of life in persons at risk for psychosisS Ruhrmann
Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
Acta Psychiatr Scand 117:357-68. 2008..Subjective quality of life (sQoL) and potentially contributing factors were investigated in individuals putatively in an early (EIPS) or late initial prodromal state (LIPS) and healthy controls (HC)...
A prospective study of factors influencing adherence to a continuous neuroleptic treatment program in schizophrenia patients during 2 yearsM Linden
Department of Psychiatry, Freie Universitat Berlin, Germany
Schizophr Bull 27:585-96. 2001..Future research should focus more on context factors in the search for clinically meaningful explanations of patient dropout from treatment...
Switching antipsychotics in inpatient schizophrenia care: predictors and outcomesStefan Weinmann
Department of Psychiatry and Psychotherapy, Heinrich Heine University Duesseldorf, Duesseldorf, Germany
J Clin Psychiatry 65:1099-105. 2004..The primary aim was to assess factors associated with antipsychotic switching and to compare disease course with regard to mental state and social functioning...
Depression during an acute episode of schizophrenia or schizophreniform disorder and its impact on treatment responseMarkus Jager
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
Psychiatry Res 158:297-305. 2008..Therefore, the hypothesis that depressive symptoms are predictive of a favorable treatment response was not supported by the present study...
Public attitudes towards people with mental illness in six German cities: results of a public survey under special consideration of schizophreniaW Gaebel
Department of Psychiatry and Psychotherapy, Heinrich-Heine-University, , Bergische Landstrasse 2, 40629 Duesseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 252:278-87. 2002....
Acute effects of treatment for prodromal symptoms for people putatively in a late initial prodromal state of psychosisS Ruhrmann
Department of Psychiatry and Psychotherapy, University Hospital of the University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
Br J Psychiatry Suppl 51:s88-95. 2007..People in a putatively late prodromal state not only have an enhanced risk for psychosis but already suffer from mental and functional disturbances...
Interventions to reduce the stigma associated with severe mental illness: experiences from the open the doors program in GermanyWolfgang Gaebel
Department of Psychiatry and Psychotherapy, , Bergische Landstrasse 2, , Germany
Can J Psychiatry 48:657-62. 2003..Improved knowledge should in turn abolish prejudice and negative perceptions and facilitate the social reintegration of those suffering from mental illness...
Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disordersRebecca Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
Schizophr Res 113:210-7. 2009..To assess criteria and to identify predictive factors for functional outcome. The criteria should cover all domains proposed by the Remission in Schizophrenia Working Group...
[Antagonist-induced opiate detoxification. Report on clinical experience as well as on short and intermediate range course]C Boehle
Psychiatrische Klinik, Heinrich Heine Universitat Dusseldorf
Nervenarzt 71:745-50. 2000..All patients relapsed after relatively short times and three out of five presented for a new detoxification treatment...
Quality assurance in psychiatry: quality indicators and guideline implementationT Wobrock
Department of Psychiatry and Psychotherapy, Georg August University Gottingen, Von Siebold Strasse 5, 37075 Gottingen, Germany
Eur Arch Psychiatry Clin Neurosci 259:S219-26. 2009..Carefully used, the use of quality indicators and improved guideline adherence can address suboptimal clinical outcomes, reduce practice variations, and narrow the gap between optimal and routine care...
Out-patient behaviour therapy in alcoholism: relapse rates after 6 monthsW Burtscheidt
Department of Psychiatry, Heinrich Heine University, Duesseldorf, Germany
Acta Psychiatr Scand 103:24-9. 2001..Furthermore, they stress the importance of professional psychiatric and psychotherapeutic engagement in the field of addiction...
Disturbed facial affect recognition in patients with schizophrenia associated with hypoactivity in distributed brain regions: a magnetoencephalographic studyM Streit
Department of Psychiatry, University of Dusseldorf, Germany
Am J Psychiatry 158:1429-36. 2001....
EEG-correlates of facial affect recognition and categorisation of blurred faces in schizophrenic patients and healthy volunteersM Streit
Department of Psychiatry, University of Dusseldorf, Bergische Landstrasse 2, D 40629, Dusseldorf, Germany
Schizophr Res 49:145-55. 2001..These results provide a first clue to the neurophysiological basis of the widely reported facial affect recognition deficit in schizophrenic patients...
Relationship between baseline severity of depression and antidepressant treatment outcomeV Henkel
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
Pharmacopsychiatry 44:27-32. 2011..Using different tools to assess baseline severity may result in different outcomes...
Residual symptoms and P300 in schizophrenic outpatientsG Juckel
Department of Psychiatry, Ludwig Maximilians University Munchen, Germany
Psychiatry Res 65:23-32. 1996..A reduced P300 amplitude may characterize a subgroup of schizophrenic patients with a disposition to cognitive disturbances and incomplete remissions...
Facial-affect recognition and visual scanning behaviour in the course of schizophreniaM Streit
Department of Psychiatry, Heinrich Heine University of Dusseldorf, Germany
Schizophr Res 24:311-7. 1997..Given their time stability, the disturbances might have a trait-like character...
Orthostatic challenge during neuroleptic test dose: a possible predictor of short-term outcomeH P Volz
Department of Psychiatry, University of Bonn, Germany
Neuropsychobiology 30:94-100. 1994..Results are discussed in relation to arousal theories and central dopaminergic activity in schizophrenia...
Adherence to guidelines for treatment of depression in in-patientsFrank Schneider
Department of Psychiatry and Psychotherapy, University of Aachen RWTH, Pauwelsstrasse 30, 52074 Aachen, Germany
Br J Psychiatry 187:462-9. 2005..Adherence to treatment guidelines enhances treatment outcome. However, in clinical practice many patients with depression do not receive appropriate treatment...
Short-term treatment with risperidone or haloperidol in first-episode schizophrenia: 8-week results of a randomized controlled trial within the German Research Network on SchizophreniaHans Jurgen Moller
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
Int J Neuropsychopharmacol 11:985-97. 2008..Risperidone has better extrapyramidal tolerability and treatment retention rate than the equivalent dose of haloperidol in these patients...
Evaluation of factors influencing medication compliance in inpatient treatment of psychotic disordersBirgit Janssen
Department of Psychiatry and Psychotherapy, Heinrich Heine University Duesseldorf, Bergische Landstr 2, 40629 Duesseldorf, Germany
Psychopharmacology (Berl) 187:229-36. 2006..Short- and long-term compliance to prescribed antipsychotic drugs is of particular concern in regard to medication choice and treatment outcome in the care of psychotic disorders...
Subcortical correlates of craving in recently abstinent alcoholic patientsF Schneider
Department of Psychiatry and Psychotherapy, University of Bonn, Germany
Am J Psychiatry 158:1075-83. 2001..This study investigated functional cerebral correlates of craving in alcoholic patients and examined the state/trait characteristics of the regional cerebral network implicated in craving...
The tolerability of rTMS treatment in schizophrenia with respect to cognitive functionM Mittrach
Department of Psychiatry and Psychotherapy, Heinrich Heine University, Dusseldorf, Germany
Pharmacopsychiatry 43:110-7. 2010..The purpose of this study was to assess tolerability and safety of high-frequency rTMS with regard to cognitive performance when conducted as "add-on" treatment in chronic schizophrenia in-patients (n=32)...
Quality of life and subjective well-being in schizophrenia and schizophrenia spectrum disorders: valid predictors of symptomatic response and remission?Rebecca Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
World J Biol Psychiatry 11:729-38. 2010..To examine quality of life and subjective well-being as predictors of symptomatic treatment outcome...
Stability of emotional dysfunctions? A long-term fMRI study in first-episode schizophreniaMartina Reske
Department of Psychiatry and Psychotherapy, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
J Psychiatr Res 41:918-27. 2007..This study aimed at determining changes of mood-related neural correlates under standardized pharmacological therapy in first-episode schizophrenia...
Remediation of impairments in facial affect recognition in schizophrenia: efficacy and specificity of a new training programWolfgang Wolwer
Department of Psychiatry and Psychotherapy, University of Duesseldorf, Rhineland State Clinics, Bergische Landstrasse 2, D 40629 Duesseldorf, Germany
Schizophr Res 80:295-303. 2005..The present study investigates the efficacy and specificity of a new training program for the remediation of such impairments...
Prediction of symptom remission in schizophrenia during inpatient treatmentMarkus Jager
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
World J Biol Psychiatry 10:426-34. 2009..The present study applied the symptom-severity component of these criteria to a sample of inpatients in order to determine the rates of remission during inpatient treatment and to explore predictors of remission...
Dopamine D2 receptor binding before and after treatment of major depression measured by [123I]IBZM SPECTA Klimke
Department of Psychiatry, University of Dusseldorf, Germany
Psychiatry Res 90:91-101. 1999..IBZM binding increased in treatment responders and decreased in non-responders. In accordance with animal studies, the results suggest an association between changes in the dopaminergic system and treatment response in major depression...
Functional serotonin 1A receptor variant influences treatment response to atypical antipsychotics in schizophreniaRainald Mossner
Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany
Pharmacogenet Genomics 19:91-4. 2009..003). The functional variant of the 5-HT1A receptor thus influences the response of schizophrenia patients to atypical antipsychotics and may be useful in the future to predict the pharmacogenetics of negative symptoms...
Improving quality of care for depression: the German Action Programme for the implementation of evidence-based guidelinesMartin Härter
Department of Psychiatry and Psychotherapy, University of Freiburg, Freiburg, Germany
Int J Qual Health Care 18:113-9. 2006..Throughout the 1990s, educational initiatives were started for implementing guidelines. Evidence-based guidelines on depression have been formulated in many countries...
An early improvement threshold to predict response and remission in first-episode schizophreniaRebecca Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstrasse 7, Muenchen 80336, Germany
Br J Psychiatry 196:460-6. 2010..Early improvement with treatment is thought to be important in patients with first-episode schizophrenia, yet a valid definition is still outstanding...
Internal capsule size associated with outcome in first-episode schizophreniaThomas Wobrock
Department of Psychiatry and Psychotherapy, Georg August University Gottingen, Gottingen, Germany
Eur Arch Psychiatry Clin Neurosci 259:278-83. 2009..In conclusion, reduced maximal area of ALIC, which can be interpreted as a disturbance of fronto-thalamic connectivity, is associated with poor outcome during the 1 year course of first-episode schizophrenia...
Psychopathological characteristics and treatment response of first episode compared with multiple episode schizophrenic disordersMarkus Jager
Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
Eur Arch Psychiatry Clin Neurosci 257:47-53. 2007..The aim was to investigate the hypothesis that patients with first episode schizophrenic disorders have a more favorable treatment response than those with multiple episodes...
[Developmental process of DGPPN quality indicators]I Großimlinghaus
Klinik und Poliklinik fur Psychiatrie und Psychotherapie, LVR Klinikum Düsseldorf, Medizinische Fakultat, Heinrich Heine Universitat, Bergische Landstr 2, 40629 Düsseldorf, Deutschland
Nervenarzt 84:350-65. 2013..The German Association for Psychiatry and Psychotherapy (DGPPN) has developed trans-sectoral quality indicator sets for four mental disorders with high prevalence (alcohol dependence, dementia, depression and schizophrenia)...
Assessing the opinions and experiences of German-speaking psychiatrists regarding necessary changes for the 11th revision of the mental disorders chapter of the International Classification of Disorders (ICD-11)J Zielasek
Department of Psychiatry and Psychotherapy, Heinrich Heine University, LVR Klinikum Düsseldorf, Bergische Landstrasse 2, Dusseldorf, Germany
Eur Psychiatry 25:437-42. 2010..Information about clinicians' experiences should be combined with scientific evidence for the revision process of ICD-11...
Standardized remission criteria in schizophrenia: descriptive validity and comparability with previously used outcome measuresM Jager
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
Pharmacopsychiatry 41:190-5. 2008..Standardized consensus criteria for remission in schizophrenia were recently proposed. As yet, the validity of these criteria and their comparability with previously used outcome measures are unclear...
Etiopathogenetic mechanisms in long-term course of schizophreniaP Falkai
Department of Psychiatry and Psychotherapy, University of the Saarland, 66421 Homburg Saar, Germany
Pharmacopsychiatry 37:S136-40. 2004..The attempt is made to connect prefrontal grey matter loss with post-mortem findings of reduced neuropil but preserved cytoarchitecture leading to recently described candidate genes and their function...
[Behavioral therapeutic methods in ambulatory treatment of alcoholism. Early results of an experimental study]W Burtscheidt
Rheinische Kliniken, Psychiatrische Klinik der Heinrich Heine Universität Düsseldorf
Fortschr Neurol Psychiatr 67:274-80. 1999....
Attitude towards adherence in patients with schizophrenia at dischargeRebecca Schennach-Wolff
Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
J Psychiatr Res 43:1294-301. 2009....
Abnormal neuroendocrine response to clomipramine in hereditary affective psychosisJoachim Cordes
Department of Psychiatry, Heinrich Heine University, Dusseldorf, Germany
Depress Anxiety 26:E111-9. 2009..In this study, the neuroendocrine responses to clomipramine were assessed in remitted patients suffering from hereditary depression...
Trait characteristic of impaired visuomotor integration during Trail-Making Test B performance in schizophreniaWolfgang Wolwer
Department of Psychiatry, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
Neuropsychobiology 48:59-67. 2003..Thus, the abnormalities in the process of TMT-B performance proved to be reliable and stable trait characteristics in schizophrenia...
German research network on schizophrenia-bridging the gap between research and careWolfgang Wolwer
German Research Network on Schizophrenia, Department of Psychiatry, Heinrich Heine University, Bergische Landstrasse 2, 12 05 10, 40605 Düsseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 253:321-9. 2003..The network is mainly funded by the German Ministry for Research spanning a period of 5 years...
Prevention of rehospitalization in schizophrenia: results of an integrated care project in GermanyChristian Schmidt-Kraepelin
LVR Klinikum Düsseldorf, Department of Psychiatry and Psychotherapy, Heinrich Heine University Dusseldorf, Bergische Landstrasse 2, 40629 Düsseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 259:S205-12. 2009..The model project described is an important step to gain evidence and experience with integrated care for patients with schizophrenia...
Effects of 10 Hz repetitive transcranial magnetic stimulation (rTMS) on clinical global impression in chronic schizophreniaJoachim Cordes
Department of Psychiatry and Psychotherapy, Heinrich Heine University of Dusseldorf, Bergische Landstr 2, D 40629 Düsseldorf, Germany
Psychiatry Res 177:32-6. 2010..However, in our study this beneficial effect was restricted to subjects with pronounced negative symptoms. CLINICAL TRIAL REGISTRATION INFORMATION: ClinicalTrial.gov Identifier: NCT00169689, http://www.clinicaltrials.gov...
A coding variant of the novel serotonin receptor subunit 5-HT3E influences sustained attention in schizophrenia patientsLeonhard Lennertz
Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany
Eur Neuropsychopharmacol 20:414-20. 2010..This study provides additional evidence for a role of the serotonergic system and the 5-HT3 receptor in schizophrenia...
[The image of people with mental illness in movies: effects on beliefs, attitudes and social distance, considering as example the movie "The white noise"]Anja Baumann
Klinik und Poliklink für Psychiatrie und Psychotherapie der Heinrich Heine Universität Düsseldorf
Psychiatr Prax 30:372-8. 2003..To examine the impact of the movie "The White Noise" on the audience's beliefs and attitudes towards schizophrenia...
[Subjectively-perceived inappropriate treatment of depressed patients in general and psychiatric practice]Frank Schneider
Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitat Dusseldorf, Rheinische Kliniken Düsseldorf
Z Arztl Fortbild Qualitatssich 97:57-66. 2003..The results indicate a considerable need for guideline training and improvement of networking and co-operation between GPs and specialists as well as between inpatient and outpatient settings...
Influence of synaptic serotonin level on [18F]altanserin binding to 5HT2 receptors in manRolf Larisch
Department of Nuclear Medicine, Heinrich Heine University of Dusseldorf, Moorenstr 5, Dusseldorf, Germany
Behav Brain Res 139:21-9. 2003..The paradigm might, thus, be useful to estimate serotonin release in vivo. Pretreatment with serotonergic antidepressants reduces the effect of clomipramine...
[Cannabinoids in multiple sclerosis. Opportunity or hazard?]Oliver Neuhaus
Neurologische Klinik, Heinrich Heine Universitat, Dusseldorf
Nervenarzt 75:1022-6. 2004..In this review, the results of the CAMS study are discussed in the context of previous trials, the putative mechanism of action of cannabinoids and their adverse event profile...
[Cost optimization of the outpatient management of depression]Ralph Menke
Klinik und Poliklinik fur Psychiatrie und Psychotherapie, der Universität, Rheinische Kliniken Düsseldorf
Z Arztl Fortbild Qualitatssich 97:74-9. 2003..This includes focussing on target areas typical of depression as well as improving outcome by controlling process elements during treatment...
The German Research Network on Schizophrenia--impact on the management of schizophreniaWolfgang Wolwer
Department of Psychiatry and Psychotherapy, Heinrich Heine University Dusseldorf, Postbox 12 05 10, D 40605 Düsseldorf, Germany
Dialogues Clin Neurosci 8:115-21. 2006....
Impaired visuomotor integration in acute schizophreniaWolfgang Wolwer
Department of Psychiatry Heinrich Heine University Düsseldorf, Bergische Landstrasse 2, P O Box 12 05 10, 40605 Düsseldorf, Germany
World J Biol Psychiatry 4:124-8. 2003....
Further evidence for a functional role of the glutamate receptor gene GRM3 in schizophreniaRainald Mossner
Department of Psychiatry and Psychotherapy, University of Bonn, Sigmund Freud Strasse 25, Germany
Eur Neuropsychopharmacol 18:768-72. 2008..008). Our results provide further evidence for the potential importance of the glutamate receptor GRM3 in schizophrenia, and indicate that the novel antipsychotic LY2140023 may actually be targeting a pathogenic pathway of schizophrenia...
Neuropsychological impairments predict the clinical course in schizophreniaWolfgang Wolwer
Department of Psychiatry and Psychotherapy, Heinrich Heine University Düsseldorf Rhineland State Clinics Düsseldorf, Bergische Landstrasse 2, Dusseldorf, Germany
Eur Arch Psychiatry Clin Neurosci 258:28-34. 2008....
Impaired Trail-Making Test-B performance in patients with acute schizophrenia is related to inefficient sequencing of planning and actingWolfgang Wolwer
Department of Psychiatry, Heinrich Heine University, Bergische Landstrasse 2, POB 12 05 10, D 40605 Düsseldorf, Germany
J Psychiatr Res 36:407-16. 2002....
A novel MRI-biomarker candidate for Alzheimer's disease composed of regional brain volume and perfusion variablesC Luckhaus
Department of Psychiatry and Psychotherapy, Heinrich Heine University, Duesseldorf, Germany
Eur J Neurol 17:1437-44. 2010..We compared single variables and combinations regarding their power for optimizing diagnostic accuracy...
