Research Topics
| R DielSummaryAffiliation: Heinrich Heine University Country: Germany Publications
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Detail Information
Publications
Comparative performance of tuberculin skin test, QuantiFERON-TB-Gold In Tube assay, and T-Spot.TB test in contact investigations for tuberculosisRoland Diel
School of Public Health c o Institute of Medical Sociology, University of Dusseldorf, Dusseldorf, Germany
Chest 135:1010-8. 2009....
Predictive value of a whole blood IFN-gamma assay for the development of active tuberculosis disease after recent infection with Mycobacterium tuberculosisRoland Diel
School of Public Health c o Institute of Medical Sociology, University of Dusseldorf, Postbox 101007, 40001 Dusseldorf, Germany
Am J Respir Crit Care Med 177:1164-70. 2008..However, their prognostic value for progression from latent tuberculosis infection (LTBI) to active TB has yet to be established...
Cost-effectiveness of interferon-gamma release assay testing for the treatment of latent tuberculosisR Diel
School of Public Health, University of Dusseldorf, Germany
Eur Respir J 30:321-32. 2007..TB was used. Using T-SPOT.TB alone or in combination with the tuberculin skin test for screening of close contacts before latent tuberculosis infection treatment is highly cost-effective in reducing the disease burden of tuberculosis...
Cost-effectiveness of interferon-gamma release assay screening for latent tuberculosis infection treatment in GermanyRoland Diel
School of Public Health, c o Institute for Medical Sociology, Heinrich Heine University, Post Box 101007, D 40001 Dusseldorf, Germany
Chest 131:1424-34. 2007....
Tuberculosis contact investigation with a new, specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated personsR Diel
School of Public Health, University of Dusseldorf, Germany
Respir Res 7:77. 2006..BCG-vaccination can confound tuberculin skin test (TST) reactions in the diagnosis of latent tuberculosis infection...
Cost-optimisation of screening for latent tuberculosis in close contactsR Diel
School of Public Health, c o Institute for Medical Sociology, Heinrich Heine University, P O Box 101007, D 40001 Dusseldorf, Germany
Eur Respir J 28:35-44. 2006..Screening for tuberculosis by combining tuberculin skin testing and QuantiFERON-TB Gold markedly reduces public health costs compared with tuberculin skin test screening alone...
[Contribution of the Public Health Service to cost of illness studies]R Diel
Heinrich Heine Universitat Dusseldorf
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 48:1170-5. 2005..This could also contribute to improving cooperation between public health authorities and schools of public health in this rapidly developing scientific field...
Cost-effectiveness of isoniazid chemoprevention in close contactsR Diel
School of Public Health, c o Institute for Medical Sociology, Heinrich Heine University, Post Box 101007, D 40001 Dusseldorf, Germany
Eur Respir J 26:465-73. 2005..In conclusion, isoniazid chemoprevention in Germany is a highly cost-effective approach for reducing the burden of tuberculosis in recently converted young and middle-aged adults...
Transmission of hepatitis B in Hamburg, Germany, 1998-2002: a prospective, population-based studyR Diel
School of Public Health c o Institute of Medical Sociology, Heinrich Heine University, Postfach 101007, 40001 Dusseldorf, Germany
Med Microbiol Immunol 194:193-9. 2005..The current national policy of vaccination in defined age groups should be extended to the immunization of all children of foreign-born parents as well as the screening and immunisation of susceptible foreign-born adults...
The cost structure of lung tuberculosis in GermanyRoland Diel
School of Public Health c o Institute for Medical Sociology, Heinrich Heine University, Dusseldorf, Germany
Eur J Health Econ 5:243-51. 2004..Consistent implementation of the recommendations of the German DZK is still necessary in order to reduce the significant economic impact of TB disease resulting in high health and socioeconomic costs...
Ongoing outbreak of tuberculosis in a low-incidence community: a molecular-epidemiological evaluationR Diel
School of Public Health, , , Germany
Int J Tuberc Lung Dis 8:855-61. 2004..The fact that conventional contact tracing is insufficient for the detection of chains of transmission in this milieu indicates the need for an improved, location-based approach, e.g., the implementation of an outreach strategy...
Transmission of hepatitis A in hamburg, germany, 1998-1999--A prospective population based studyR Diel
School of Public Health, University of Dusseldorf, Germany
Eur J Epidemiol 17:175-82. 2001..Nevertheless, because hygienic standards may change with time, this policy should be supplemented by targeted vaccination of groups at risk...
Epidemiology of tuberculosis in Hamburg, Germany: long-term population-based analysis applying classical and molecular epidemiological techniquesRoland Diel
School of Public Health, , , Germany
J Clin Microbiol 40:532-9. 2002..The data presented also indicate that improved TB control strategies, including the use of RFLP for the detection of transmission chains, are needed for TB control in the setting of countries with a low incidence of TB...
Outcome of tuberculosis treatment in Hamburg: a survey, 1997-2001R Diel
School of Public Health, , Heinrich-Heine-University, , Germany
Int J Tuberc Lung Dis 7:124-31. 2003....
Molecular epidemiology of tuberculosis among immigrants in Hamburg, GermanyRoland Diel
School of Public Health, , Germany
J Clin Microbiol 42:2952-60. 2004..In conclusion, only a minority of TB cases among foreign-born individuals are detected by screening of asylum seekers or conventional contact tracing. Recent transmission does not play an important role in TB among immigrants in Hamburg...
Occupational risk of tuberculosis transmission in a low incidence areaRoland Diel
School of Public Health, University of Dusseldorf, Germany
Respir Res 6:35. 2005..To investigate the occupational risk of tuberculosis (TB) infection in a low-incidence setting, data from a prospective study of patients with culture-confirmed TB conducted in Hamburg, Germany, from 1997 to 2002 were evaluated...
Interferon-gamma release assay for the diagnosis of latent TB infection--analysis of discordant results, when compared to the tuberculin skin testAlbert Nienhaus
Institution for Statutory Accident Insurance and Prevention in the Health and Welfare Services, Department of Occupational Health Research, Hamburg, Germany
PLoS ONE 3:e2665. 2008..Therefore we assessed to which extent discordant results can be explained by potential risk factors such as age, BCG vaccination and migration...
Assessment of an optimized mycobacterial interspersed repetitive- unit-variable-number tandem-repeat typing system combined with spoligotyping for population-based molecular epidemiology studies of tuberculosisMara Cardoso Oelemann
INSERM, U629, Institut Pasteur de Lille, Lille, France
J Clin Microbiol 45:691-7. 2007..tuberculosis transmission...
Rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage enzyme-linked immunospotClaudia Jafari
Division of Clinical Infectious Diseases, Research Center Borstel, Parkallee 35, Borstel, Germany
Am J Respir Crit Care Med 174:1048-54. 2006..CONCLUSION: Smear-negative pulmonary tuberculosis can be diagnosed rapidly by identification of MTB-specific cells in the BAL fluid...
Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population genetics and epidemiologyKarine Brudey
, Institut Pasteur de Guadeloupe, Guadeloupe
BMC Microbiol 6:23. 2006..The building and mining of extended MTC polymorphic genetic databases is in progress...
Review of epidemiological studies on the occupational risk of tuberculosis in low-incidence areasAndreas Seidler
Institute of Occupational Medicine, Johann Wolfgang Goethe University, Frankfurt Main, Germany
Respiration 72:431-46. 2005..There is a need for large population-based studies with precise definition of exposure, which should include molecular epidemiologic methods in the investigation of occupational risk factors of tuberculosis...
