Stefan Heim

Summary

Country: Germany

Publications

  1. doi request reprint Effects of lexicality and word frequency on brain activation in dyslexic readers
    Stefan Heim
    Section Structural functional Brain Mapping, Department of Psychiatry, Psychotherapy, and Psychosomatics, Medical School, RWTH Aachen University, Germany
    Brain Lang 125:194-202. 2013
  2. ncbi request reprint The structure and dynamics of normal language processing: insights from neuroimaging
    Stefan Heim
    Research Centre Julich, Institute of Medicine, 52425 Julich, Germany
    Acta Neurobiol Exp (Wars) 65:95-116. 2005
  3. ncbi request reprint Cognitive subtypes of dyslexia
    Stefan Heim
    Research Centre Julich, Institute of Neurosciences and Biophysics, Julich, Germany
    Acta Neurobiol Exp (Wars) 68:73-82. 2008
  4. doi request reprint The determiner congruency effect in language production investigated with functional MRI
    Stefan Heim
    Research Centre Julich, Institute for Neurosciences and Biophysics, Julich, Germany
    Hum Brain Mapp 30:928-40. 2009
  5. doi request reprint Specialisation in Broca's region for semantic, phonological, and syntactic fluency?
    Stefan Heim
    Research Centre Julich, Institute of Neurosciences and Biophysics INB 3, Julich, Germany
    Neuroimage 40:1362-8. 2008
  6. ncbi request reprint Syntactic gender processing in the human brain: a review and a model
    Stefan Heim
    Research Centre Julich, Institute for Neurosciences and Biophysics, Leo Brandt Strasse 5, 52425 Julich, Germany
    Brain Lang 106:55-64. 2008
  7. ncbi request reprint Effective connectivity of the left BA 44, BA 45, and inferior temporal gyrus during lexical and phonological decisions identified with DCM
    Stefan Heim
    Research Centre Julich, Institute of Neuroscience and Biophysics, Julich, Germany
    Hum Brain Mapp 30:392-402. 2009
  8. ncbi request reprint Modality-independent involvement of the left BA 44 during lexical decision making
    Stefan Heim
    Research Centre Julich, Institute of Neurosciences and Biophysics INB 3, 52425 Julich, Germany
    Brain Struct Funct 212:95-106. 2007
  9. ncbi request reprint BA 44 in Broca's area supports syntactic gender decisions in language production
    Stefan Heim
    Research Centre Julich, Institute of Medicine, AG Brain Mapping, Julich, Germany
    Neuroreport 17:1097-101. 2006
  10. ncbi request reprint Prosodic pitch accents in language comprehension and production: ERP data and acoustic analyses
    Stefan Heim
    Institute of Medicine, Research Centre Julich, 52425 Julich, Germany
    Acta Neurobiol Exp (Wars) 66:55-68. 2006

Detail Information

Publications38

  1. doi request reprint Effects of lexicality and word frequency on brain activation in dyslexic readers
    Stefan Heim
    Section Structural functional Brain Mapping, Department of Psychiatry, Psychotherapy, and Psychosomatics, Medical School, RWTH Aachen University, Germany
    Brain Lang 125:194-202. 2013
    ..Additionally, data from four compensated adult dyslexics are reported and discussed, which hint at the importance of both Broca's and Wernicke's region for recovery from childhood dyslexia...
  2. ncbi request reprint The structure and dynamics of normal language processing: insights from neuroimaging
    Stefan Heim
    Research Centre Julich, Institute of Medicine, 52425 Julich, Germany
    Acta Neurobiol Exp (Wars) 65:95-116. 2005
    ..This insight leads to some tentative conclusions about remediation strategies in dyslexics with selective (e.g., phonological) deficits...
  3. ncbi request reprint Cognitive subtypes of dyslexia
    Stefan Heim
    Research Centre Julich, Institute of Neurosciences and Biophysics, Julich, Germany
    Acta Neurobiol Exp (Wars) 68:73-82. 2008
    ..These results indicate that dyslexia may result from distinct cognitive impairments. As a consequence, prevention and remediation programmes should be specifically targeted for the individual child's deficit pattern...
  4. doi request reprint The determiner congruency effect in language production investigated with functional MRI
    Stefan Heim
    Research Centre Julich, Institute for Neurosciences and Biophysics, Julich, Germany
    Hum Brain Mapp 30:928-40. 2009
    ..The latter regions are known to be involved in the processing of incongruence and conflict in general. The data thus reveal the involvement of the left BA 44 in the selection of determiners for language production...
  5. doi request reprint Specialisation in Broca's region for semantic, phonological, and syntactic fluency?
    Stefan Heim
    Research Centre Julich, Institute of Neurosciences and Biophysics INB 3, Julich, Germany
    Neuroimage 40:1362-8. 2008
    ..In contrast, phonological verbal fluency additionally involved the left BA 44. In conclusion, different parts of Broca's region support task-specific and more general processes in verbal fluency...
  6. ncbi request reprint Syntactic gender processing in the human brain: a review and a model
    Stefan Heim
    Research Centre Julich, Institute for Neurosciences and Biophysics, Leo Brandt Strasse 5, 52425 Julich, Germany
    Brain Lang 106:55-64. 2008
    ..The left BA 45 is involved in the strategic generation of morphological cues that facilitate gender processing. Model implications for aphasic patients with lesions including or excluding parts of Broca's speech region are discussed...
  7. ncbi request reprint Effective connectivity of the left BA 44, BA 45, and inferior temporal gyrus during lexical and phonological decisions identified with DCM
    Stefan Heim
    Research Centre Julich, Institute of Neuroscience and Biophysics, Julich, Germany
    Hum Brain Mapp 30:392-402. 2009
    ..This model is in line with the hypothesis that left BA 45 supports explicit lexical decisions during visual word recognition based on lexical access in the ITG...
  8. ncbi request reprint Modality-independent involvement of the left BA 44 during lexical decision making
    Stefan Heim
    Research Centre Julich, Institute of Neurosciences and Biophysics INB 3, 52425 Julich, Germany
    Brain Struct Funct 212:95-106. 2007
    ..These results indicate that the left BA 44 as a distinct sub-part of Broca's region plays an important role in lexical decision making independently of stimulus modality and decision times...
  9. ncbi request reprint BA 44 in Broca's area supports syntactic gender decisions in language production
    Stefan Heim
    Research Centre Julich, Institute of Medicine, AG Brain Mapping, Julich, Germany
    Neuroreport 17:1097-101. 2006
    ..Using cytoarchitectonic probability maps, the activation was localized at Brodmann's area 44. The data suggest that Brodmann's area 44 in Broca's area is a shared neural correlate for gender processing in production and comprehension...
  10. ncbi request reprint Prosodic pitch accents in language comprehension and production: ERP data and acoustic analyses
    Stefan Heim
    Institute of Medicine, Research Centre Julich, 52425 Julich, Germany
    Acta Neurobiol Exp (Wars) 66:55-68. 2006
    ....
  11. ncbi request reprint Head motion during overt language production in functional magnetic resonance imaging
    Stefan Heim
    Research Centre Julich, Institute of Medicine, Julich, Germany
    Neuroreport 17:579-82. 2006
    ..The data encourage further use of overt language production in functional magnetic resonance imaging with careful head fixation but no bite-bar...
  12. ncbi request reprint The role of the left Brodmann's areas 44 and 45 in reading words and pseudowords
    Stefan Heim
    Research Centre Julich, Institute of Medicine, AG Brain Mapping, 52425 Julich, Germany
    Brain Res Cogn Brain Res 25:982-93. 2005
    ..The results are interpreted within a dual-route model of reading with the left BA 44 supporting grapheme-to-phoneme conversion and the left BA 45 being related to explicit lexical search...
  13. ncbi request reprint A dual-route account for access to grammatical gender: evidence from functional MRI
    Stefan Heim
    Research Centre Julich, Institute of Medicine, 52425 Julich, Germany
    Anat Embryol (Berl) 210:473-83. 2005
    ..These results speak in favour of a dual-route account for modelling the access to grammatical gender information during language comprehension...
  14. doi request reprint From a concept to a word in a syntactically complete sentence: an fMRI study on spontaneous language production in an overt picture description task
    Marion Grande
    Section Neurological Cognition Research, Department of Neurology, Medical School, RWTH Aachen University, Aachen, Germany
    Neuroimage 61:702-14. 2012
    ..This opens up new prospects for the analysis of spontaneous language production during fMRI...
  15. pmc Left cytoarchitectonic area 44 supports selection in the mental lexicon during language production
    Stefan Heim
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany
    Brain Struct Funct 213:441-56. 2009
    ..Overall, the activation pattern is in line with the hypothesis that area 44 generally supports selection processes during noun production at several levels of the mental lexicon...
  16. ncbi request reprint Distinct neural signatures of cognitive subtypes of dyslexia: effects of lexicality during phonological processing
    Muna van Ermingen-Marbach
    Department of Psychiatry, Psychotherapy and Psychosomatics, Medical School, Section Structural functional Brain Mapping, RWTH Aachen University, Aachen, Germany
    Acta Neurobiol Exp (Wars) 73:404-16. 2013
    ..In general, the results stress the importance of considering subtypes of dyslexia differentially in order to obtain better insights in the neurocognitive mechanisms of impaired and successful reading. ..
  17. pmc Different roles of cytoarchitectonic BA 44 and BA 45 in phonological and semantic verbal fluency as revealed by dynamic causal modelling
    Stefan Heim
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
    Neuroimage 48:616-24. 2009
    ..To conclude, DCM provided additional insights into the roles of BA 44 and BA 45 during verbal fluency revealing the involvement of BA 45 in lexical retrieval and the relevance of BA 44 for phonological processing during word generation...
  18. doi request reprint Eliciting dyslexic symptoms in proficient readers by simulating deficits in grapheme-to-phoneme conversion and visuo-magnocellular processing
    Nicole Tholen
    Research Centre Julich, Institute of Neurosciences and Medicine INM 1 and INM 3, Germany
    Dyslexia 17:268-81. 2011
    ..The paradigm is thus a potential means of generating novel hypotheses about dyslexia, which can easily be tested with normal readers before screening and recruiting real dyslexics...
  19. doi request reprint Word frequency effects in the left IFG in dyslexic and normally reading children during picture naming and reading
    Marion Grande
    Section Neurological Cognition Research, Department of Neurology, Medical School, RWTH Aachen University, Aachen, Germany
    Neuroimage 57:1212-20. 2011
    ..Apart from extending previous knowledge from studies with adults to childhood, the study sheds further light on a potential neural mechanism for deficient grapheme-to-phoneme conversion in dyslexic children...
  20. pmc Dissociated neural processing for decisions in managers and non-managers
    Svenja Caspers
    Institute of Neuroscience and Medicine, Research Centre Julich, Julich, Germany
    PLoS ONE 7:e43537. 2012
    ..More generally, the findings reveal how different professional requirements might modulate cognitive decision processing...
  21. doi request reprint Is the motor or the garage more important to the car? The difference between semantic associations in single word and sentence production
    Juliane Muehlhaus
    Department of Psychiatry, Psychotherapy and Psychosomatics, Medical School, RWTH Aachen University, Pauwelsstr 30, 52074 Aachen, Germany
    J Psycholinguist Res 42:37-49. 2013
    ..In contrast, during sentence production the syntactic processing at the lexical level seem to be more important than types of semantic associations at the conceptual level...
  22. doi request reprint Cognitive levels of performance account for hemispheric lateralisation effects in dyslexic and normally reading children
    Stefan Heim
    Department of Psychiatry and Psychotherapy, University Hospital Aachen, RWTH Aachen University, Aachen, Germany
    Neuroimage 53:1346-58. 2010
    ..In line with earlier findings in the literature, these data hint at a global change in hemispheric asymmetry during cognitive processing in dyslexic readers, which, in turn, might affect reading proficiency...
  23. doi request reprint Left cytoarchitectonic BA 44 processes syntactic gender violations in determiner phrases
    Stefan Heim
    Department of Psychiatry and Psychotherapy, RWTH Aachen University, Germany
    Hum Brain Mapp 31:1532-41. 2010
    ....
  24. ncbi request reprint The influence of handedness on hemispheric interaction during word production: insights from effective connectivity analysis
    Stefanie Abel
    Section Neuropsychology, RWTH Aachen University, Aachen, Germany
    Brain Connect 1:219-31. 2011
    ..In right-handers, the according left-hemisphere connection was significant, but connectivities were rather symmetrical. These findings reveal significant and unique right-hemisphere contributions to word production...
  25. ncbi request reprint Longitudinal changes in brains of patients with fluent primary progressive aphasia
    Stefan Heim
    Section Structural functional Brain Mapping, Department of Psychiatry, Psychotherapy, and Psychosomatics, Medical School, RWTH Aachen University, Aachen, Germany JARA Translational Brain Medicine, Jülich and Aachen, Germany Research Centre Jülich, Institute of Neuroscience and Medicine INM 1, INM 2, Julich, Germany Section Neurological Cognition Research, Department of Neurology, Medical School, RWTH Aachen University, Aachen, Germany Electronic address
    Brain Lang 131:11-9. 2014
    ....
  26. doi request reprint The time course of neurolinguistic and neuropsychological symptoms in three cases of logopenic primary progressive aphasia
    Louise Etcheverry
    Research Centre Julich, Institute for Neuroscience and Medicine INM 1, INM 2, Julich, Germany
    Neuropsychologia 50:1708-18. 2012
    ..These deficits may further interact and thus form a multi-causal basis for the patients' problems in every-day life which need to be considered when planning individually targeted intervention in PPA...
  27. ncbi request reprint Why the leash constrains the dog: the impact of semantic associations on sentence production
    Katharina Sass
    Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Aachen, Germany
    Acta Neurobiol Exp (Wars) 70:435-53. 2010
    ..Hence, associations have an important influence on producing speech but the impact is varied by the context, i.e., single word or sentential...
  28. doi request reprint Taboo: a novel paradigm to elicit aphasia-like trouble-indicating behaviour in normally speaking individuals
    Elisabeth Meffert
    Section Neurological Cognition Research, Department of Neurology, Medical School, RWTH Aachen University, Germany
    J Psycholinguist Res 40:307-26. 2011
    ..Consequently, the paradigm is applicable for further studies, e.g. for bringing forward the understanding of spontaneous language production or for comparing the neurofunctional basis of errors in healthy and aphasic speakers...
  29. ncbi request reprint Testing anatomically specified hypotheses in functional imaging using cytoarchitectonic maps
    Simon B Eickhoff
    Institut fur Medizin, Forschungszentrum Julich, Julich, Germany
    Neuroimage 32:570-82. 2006
    ..In combination with thresholding based on the Gaussian random field theory, these ROIs can then be applied to test anatomically specified hypotheses in functional neuroimaging studies...
  30. pmc The Role of Human Parietal Area 7A as a Link between Sequencing in Hand Actions and in Overt Speech Production
    Stefan Heim
    Section Structural functional Brain Mapping, Department of Psychiatry, Psychotherapy, and Psychosomatics, Medical School, RWTH Aachen University Aachen, Germany Research Centre Jülich, Institute of Neuroscience and Medicine INM 1 Jülich, Germany Section Clinical and Cognitive Neurosciences, Department of Neurology, Medical School, RWTH Aachen University Aachen, Germany JARA Translational Brain Medicine Jülich and Aachen, Germany
    Front Psychol 3:534. 2012
    ..In sum, the study demonstrates a previously underspecified role of the SPL in the origins of speech, and may be discussed in the light of embodiment of speech and language in the motor system...
  31. doi request reprint Experimental induction of reading difficulties in normal readers provides novel insights into the neurofunctional mechanisms of visual word recognition
    Stefan Heim
    Section Structural functional Brain Mapping, Department of Psychiatry, Psychotherapy, and Psychosomatics, Medical School, RWTH Aachen University, Pauwelsstrase 30, 52074, Aachen, Germany
    Brain Struct Funct 219:461-71. 2014
    ..The novel paradigm may thus prove useful in future studies to understand reading problems related to distinct pathways, potentially providing a link also to the understanding of real reading impairments in dyslexia. ..
  32. pmc A systems perspective on the effective connectivity of overt speech production
    Simon B Eickhoff
    Institute for Neuroscience and Biophysics Medicine INB 3, Research Centre Jülich GmbH, 52425 Julich, Germany
    Philos Trans A Math Phys Eng Sci 367:2399-421. 2009
    ..The proposed model of physiological integration during speech production may now serve as a reference for investigations into the neurobiology of pathological states such as dysarthria and apraxia of speech...
  33. pmc Moral concepts set decision strategies to abstract values
    Svenja Caspers
    Institute of Neuroscience and Medicine INM 1, INM 2, Research Centre Julich, Julich, Germany
    PLoS ONE 6:e18451. 2011
    ..These findings provide a novel perspective to future sociological and economic research as well as to the analysis of social relations by focusing on abstract value systems as triggers of specific brain responses...
  34. pmc Identifying brain systems for gaze orienting during reading: fMRI investigation of the Landolt paradigm
    Rebekka Hillen
    Department of Psychiatry, Psychotherapy and Psychosomatics, Medical School, RWTH Aachen University Aachen, Germany Section Neurological Cognition Research, Department of Neurology, Medical School, RWTH Aachen University Aachen, Germany
    Front Hum Neurosci 7:384. 2013
    ..Consequently, the Landolt paradigm may provide novel insights into the contributions of linguistic and non-linguistic factors on reading failure e.g., in developmental dyslexia. ..
  35. pmc The language-number interface in the brain: a complex parametric study of quantifiers and quantities
    Stefan Heim
    Section Structural functional Brain Mapping, Department of Psychiatry, Psychotherapy, and Psychosomatics, Medical School, RWTH Aachen University Aachen, Germany
    Front Evol Neurosci 4:4. 2012
    ..Results fortify the homology of Estimation and Comparison between humans and monkeys...
  36. pmc Neural representation of the sensorimotor speech-action-repository
    Cornelia Eckers
    Department of Phoniatrics, Pedaudiology, and Communication Disorders, Medical School, RWTH Aachen University Aachen, Germany
    Front Hum Neurosci 7:121. 2013
    ..These findings are taken to represent sensorimotor state maps of the SAR. In conclusion, the present study provided preliminary evidence for a SAR...
  37. pmc Are abstract action words embodied? An fMRI investigation at the interface between language and motor cognition
    Katrin Sakreida
    Division of Clinical and Cognitive Neurosciences, Department of Neurology, Medical School, RWTH Aachen University Aachen, Germany
    Front Hum Neurosci 7:125. 2013
    ....
  38. pmc The brain differentiates human and non-human grammars: functional localization and structural connectivity
    Angela D Friederici
    Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstrasse 1a, 04103 Leipzig, Germany
    Proc Natl Acad Sci U S A 103:2458-63. 2006
    ..Tractography data revealing differential structural connectivity signatures for these two brain areas provide additional evidence for a segregation of two areas in the left inferior frontal cortex...