Research Topics
| Lothar HeilmannSummaryCountry: Germany Publications
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Detail Information
Publications
Association between blood rheology, thrombosis and cancer survival in patients with gynecologic malignancyG F von Tempelhoff
Department of Obstetrics and Gynecology, City Hospital of Ruesselsheim, Germany
Clin Hemorheol Microcirc 22:107-30. 2000..Improvement of blood fluidity and thus oxygen transfer in the tumor-vascular-microcirculation may increase susceptibility of systemic anti-cancer therapy...
[Deep vein thrombosis in pregnancy: an increase is to be feared]G-F von Tempelhoff
, Klinikum Aschaffenburg, Am Hasenkopf 1, 63739 Aschaffenburg
Dtsch Med Wochenschr 133:527. 2008
Mean maternal second-trimester hemoglobin concentration and outcome of pregnancy: a population-based studyGeorg Friedrich von Tempelhoff
Department of Obstetrics and Gynecology Health and Care Center Ruesselsheim, Ruesselsheim, Germany
Clin Appl Thromb Hemost 14:19-28. 2008..24; 95% confidence interval, 1.54-3.31). In this population-based study from a community in Western Germany, impaired plasma volume expansion was an independent risk factor for the development of an adverse outcome of pregnancy...
Monitoring of rheologic variables during postoperative high-dose brachytherapy for uterine cancerGeorg Friedrich von Tempelhoff
Department of Obstetrics and Gynecology, City Hospital of Ruesselsheim, Ruesselsheim, Germany
Clin Appl Thromb Hemost 10:239-48. 2004..While a temporary reduction of hyperviscosity is found postoperatively and during HDR-AL in uterine cancer patients, 6 months after surgery RBC aggregation, PV, and hematocrit returned to the pretreatment range...
Blood rheology at term in normal pregnancy and in patients with adverse outcome eventsGeorg Friedrich von Tempelhoff
Department of Obstetrics and Gynecology, City Hospital of Aschaffenburg, Aschaffenburg, Germany
Clin Hemorheol Microcirc 42:127-39. 2009..However, coincidental increased RBC aggregation and hemo concentration may potentially derogate blood flow in the materno-fetal unit that is commonly traceable using vessel duplex ultra sound in pre-eclampsia...
Antithrombotic therapy in gynecologic surgery and gynecologic oncologyG F von Tempelhoff
Department of Obstetrics and Gynecology, City Hospital Ruesselsheim, Germany
Hematol Oncol Clin North Am 14:1151-69, ix. 2000....
Antiphospholipid syndrome in obstetricsLothar Heilmann
Department of Obstetrics and Gynecology, City Hospital Ruesselsheim, Germany
Clin Appl Thromb Hemost 9:143-50. 2003..The general failure rate of heparin/aspirin treatment is approximately 30%. In such cases intravenous immunoglobulin in combination with heparin and aspirin has been used to treat APLS...
Prognostic role of plasmaviscosity in breast cancerGeorg Friedrich von Tempelhoff
Department of Obstetrics and Gynecology, City Hospital of Ruesselsheim, August Bebel Strasse 59, 65428, Germany
Clin Hemorheol Microcirc 26:55-61. 2002..These findings may constitute an approach for new strategies in cancer therapy since it might be possible that reduction of plasma viscosity by treatment improves responsiveness to radio/chemotherapy and thus survival of patients...
Thrombosis--a clue of poor prognosis in primary non-metastatic breast cancer?Georg Friedrich von Tempelhoff
Department of Obstetrics and Gynecology, City Hospital of Ruesselsheim, Germany
Breast Cancer Res Treat 73:275-7. 2002
Impact of rheological variables in cancerGeorg Friedrich von Tempelhoff
Specialist for Gynecology and Obstetrics, City Hospital of Ruesselsheim, Ruesselsheim, Germany
Semin Thromb Hemost 29:499-513. 2003..Anticoagulants and anti-inflammatory substances seem most suitable at this point, because high fibrinogen turnover is an important determinant of hyperviscosity in malignancy...
Hemostatic abnormalities in patients with severe preeclampsiaLothar Heilmann
Department of Obstetrics and Gynecology, Perinatal Center, Russelsheim, Germany
Clin Appl Thromb Hemost 13:285-91. 2007..Women who develop early onset preeclampsia characterized a subgroup of patients with more and severe hematologic abnormalities than women with late preeclampsia (after 34 weeks of gestation)...
ProC Global assay in the evaluation of women with history of severe preeclampsia or HELLP syndromeLothar Heilmann
Department of Obstetrics and Gynecology, City Hospital, Ruesselsheim, Germany
Clin Appl Thromb Hemost 8:319-24. 2002..ProC Global is a new screening test to identify patients with defects of the protein C system and an activated dotting system in preeclampsia but cannot correctly cover each thrombophilic component...
A whole blood flow cytometric determination of platelet activation by unfractionated and low molecular weight heparin in vitroBernd Klein
Department of Gynecology and Obstetrics, University Hospital of the University of Technology RWTH, Pauwelsstrasse 30, 52074, Aachen, Germany
Thromb Res 108:291-6. 2002..The potentiating action of unfractionated heparin was larger. Therefore, flow cytometric results of platelet activation in patients receiving heparin should be interpreted carefully...
Antihypertensive therapy in patients with pre-eclampsia: A prospective randomised multicentre study comparing dihydralazine with urapidilJuergen R Wacker
Department of Obstetrics and Gynecology Bruchsal, Furst Stirum Klinik Bruchsal, Teaching Hospital of the University of Heidelberg, Gutleutstrasse 1 14, D 76646 Bruchsal, Baden Wuerttemberg, Germany
Eur J Obstet Gynecol Reprod Biol 127:160-5. 2006..Another particularly effective and better tolerable antihypertensive is urapidil. Yet only a few studies on limited patient collectives have been published on the clinical experience with urapidil in PIH...
