Alexander Woywodt

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. ncbi request reprint Circulating endothelial cells in vasculitis and transplantation
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Pathophysiol Haemost Thromb 33:500-2. 2003
  2. ncbi request reprint Wegener's granulomatosis
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, 30625 Hannover, Germany
    Lancet 367:1362-6. 2006
  3. ncbi request reprint A hopeless case?
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Nephrol Dial Transplant 22:1253-6. 2007
  4. ncbi request reprint From the Prague Spring to a chair in nephrology in Germany: Jan Brod (1912-1985)
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    Nephrol Dial Transplant 19:1374-7. 2004
  5. ncbi request reprint An improved assay for enumeration of circulating endothelial cells
    A Woywodt
    Department of Internal Medicine, Hannover Medical School, Carl Neuberg Strasse 1, Hannover, Germany
    Ann Hematol 83:491-4. 2004
  6. pmc A novel multimedia tool to improve bedside teaching of cardiac auscultation
    A Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Postgrad Med J 80:355-7. 2004
  7. ncbi request reprint Severe hypokalaemia: is one reason enough?
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Nephrol Dial Transplant 19:2914-7. 2004
  8. ncbi request reprint Wegener's granulomatosis--probing the untold past of the man behind the eponym
    A Woywodt
    MD, MRCP, Department of Nephrology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Rheumatology (Oxford) 45:1303-6. 2006
  9. ncbi request reprint Counting the cost: markers of endothelial damage in hematopoietic stem cell transplantation
    A Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Bone Marrow Transplant 34:1015-23. 2004
  10. pmc Circulating endothelial cells in relapse and limited granulomatous disease due to ANCA associated vasculitis
    A Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Ann Rheum Dis 65:164-8. 2006

Detail Information

Publications53

  1. ncbi request reprint Circulating endothelial cells in vasculitis and transplantation
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Pathophysiol Haemost Thromb 33:500-2. 2003
  2. ncbi request reprint Wegener's granulomatosis
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, 30625 Hannover, Germany
    Lancet 367:1362-6. 2006
  3. ncbi request reprint A hopeless case?
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Nephrol Dial Transplant 22:1253-6. 2007
  4. ncbi request reprint From the Prague Spring to a chair in nephrology in Germany: Jan Brod (1912-1985)
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    Nephrol Dial Transplant 19:1374-7. 2004
  5. ncbi request reprint An improved assay for enumeration of circulating endothelial cells
    A Woywodt
    Department of Internal Medicine, Hannover Medical School, Carl Neuberg Strasse 1, Hannover, Germany
    Ann Hematol 83:491-4. 2004
    ..The assay is simple and easy to use, thus allowing for a more widespread use of circulating endothelial cells as a marker of vascular damage...
  6. pmc A novel multimedia tool to improve bedside teaching of cardiac auscultation
    A Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Postgrad Med J 80:355-7. 2004
    ..Amalgamating traditional phonocardiography with a multimedia approach, this system represents a novel tool for bedside teaching of cardiac auscultation...
  7. ncbi request reprint Severe hypokalaemia: is one reason enough?
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Nephrol Dial Transplant 19:2914-7. 2004
  8. ncbi request reprint Wegener's granulomatosis--probing the untold past of the man behind the eponym
    A Woywodt
    MD, MRCP, Department of Nephrology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Rheumatology (Oxford) 45:1303-6. 2006
  9. ncbi request reprint Counting the cost: markers of endothelial damage in hematopoietic stem cell transplantation
    A Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Bone Marrow Transplant 34:1015-23. 2004
    ..The challenge ahead is to establish and evaluate novel markers of endothelial damage to permit early detection of disease, monitor response to treatment and evaluate different conditioning regimens...
  10. pmc Circulating endothelial cells in relapse and limited granulomatous disease due to ANCA associated vasculitis
    A Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Ann Rheum Dis 65:164-8. 2006
    ..To evaluate numbers of circulating endothelial cells (CECs) in ANCA associated vasculitis and compare vasculitic relapse with limited granulomatous disease...
  11. ncbi request reprint Circulating endothelial cells and endothelial progenitor cells after angioplasty: news from the endothelial rescue squad
    A Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    J Thromb Haemost 4:976-8. 2006
  12. ncbi request reprint Isolation and enumeration of circulating endothelial cells by immunomagnetic isolation: proposal of a definition and a consensus protocol
    A Woywodt
    Department of Medicine, Division of Nephrology, Hannover Medical School, Hannover, Germany
    J Thromb Haemost 4:671-7. 2006
    ..CD146-driven immunomagnetic isolation has gained widespread use, but the technique is hampered by the lack of a definition of CECs and the absence of a consensus for their enumeration...
  13. ncbi request reprint Circulating endothelial cells as a marker of endothelial damage in allogeneic hematopoietic stem cell transplantation
    Alexander Woywodt
    Division of Nephrology, Department of Internal Medicine, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Blood 103:3603-5. 2004
    ..These observations provide a novel marker to investigate microvascular endothelial damage and the effects of different conditioning regimens in patients undergoing HSCT...
  14. ncbi request reprint An uncommon cause of metabolic acidosis in a haemodialysis patient
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Nephrol Dial Transplant 17:929-30. 2002
  15. ncbi request reprint Circulating endothelial cells as markers for ANCA-associated small-vessel vasculitis
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, 30625, Hannover, Germany
    Lancet 361:206-10. 2003
    ..We postulated that isolation of these cells from peripheral blood might provide a novel marker of the disease and elucidate pathogenetic events...
  16. ncbi request reprint A swollen neck
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Lancet 360:1838. 2002
  17. ncbi request reprint Cytomegalovirus colitis during mycophenolate mofetil therapy for Wegener's granulomatosis
    A Woywodt
    Department of Nephrology, Franz Volhard Clinic, Charité Campus Berlin Buch, Humboldt University, Berlin, Germany
    Am J Nephrol 20:468-72. 2000
    ..We also speculate as to the potential role of previous Salmonella infection and proinflammatory cytokines in CMV reactivation. In summary, when using mycophenolate, clinicians should be more aware of CMV reactivation and disease...
  18. ncbi request reprint Nephrotoxicity of selective COX-2 inhibitors
    A Woywodt
    Department of Medicine, University of Hannover School of Medicine, Germany
    J Rheumatol 28:2133-5. 2001
    ..Therefore, COX-2 inhibitors should be used with caution in renal transplant recipients and in patients with salt depletion and renal insufficiency...
  19. pmc Geophagia: the history of earth-eating
    Alexander Woywodt
    Department of Surgery, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Gauteng Province, Republic of South Africa
    J R Soc Med 95:143-6. 2002
  20. ncbi request reprint Elevated numbers of circulating endothelial cells in renal transplant recipients
    Alexander Woywodt
    Department of Medicine, Hannover Medical School, Hannover, Germany woywodt alexander mh hannover de
    Transplantation 76:1-4. 2003
    ..Circulating endothelial cells have recently been established as a novel marker of endothelial damage in a variety of vascular disorders...
  21. doi request reprint Endothelial-derived thrombospondin-1 promotes macrophage recruitment and apoptotic cell clearance
    Torsten Kirsch
    Division of Nephrology, Department of Internal Medicine, Hannover Medical School, Germany
    J Cell Mol Med 14:1922-34. 2010
    ....
  22. pmc Detection of circulating microparticles by flow cytometry: influence of centrifugation, filtration of buffer, and freezing
    Emily Dey-Hazra
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Vasc Health Risk Manag 6:1125-33. 2010
    ..Buffers should be filtered and fresh samples should be analyzed, or storage periods will have to be standardized. Higher centrifugation speeds should be used to minimize contamination by smaller size platelets...
  23. ncbi request reprint Circulating endothelial cells are a novel marker of cyclosporine-induced endothelial damage
    Alexander Woywodt
    Medical School, Hannover, Germany
    Hypertension 41:720-3. 2003
    ..We suggest that elevated numbers of circulating endothelial cells indicate damage from calcineurin inhibitors in renal transplant recipients and that circulating endothelial cells are a novel marker of endothelial damage...
  24. doi request reprint Circulating endothelial cells and stroke: influence of stroke subtypes and changes during the course of disease
    Alexander Woywodt
    Department of Nephrology, Hannover Medical School, Hannover, Germany
    J Stroke Cerebrovasc Dis 21:452-8. 2012
    ..Circulating endothelial cells (CECs) are a novel and valuable marker of endothelial damage in a variety of vascular disorders. There is limited information as to CEC counts and the time course of CECs in subtypes of stroke...
  25. doi request reprint Rituximab as rescue therapy in anti-neutrophil cytoplasmic antibody-associated vasculitis: a single-centre experience with 15 patients
    Svjetlana Lovric
    Department of Nephrology, Hannover Medical School, Hannover, Germany
    Nephrol Dial Transplant 24:179-85. 2009
    ..Data are limited and most reports describe single patients or small numbers of patients followed prospectively...
  26. ncbi request reprint Circulating endothelial cells as a prognostic marker in thrombotic microangiopathy
    Uta Erdbruegger
    Department of Medicine, Division of Nephrology, Hannover Medical School, Hannover, Germany
    Am J Kidney Dis 48:564-70. 2006
    ..The aim of this study is to identify and count CECs during the course of TMA and evaluate whether cell numbers may serve as a prognostic marker in patients undergoing plasma exchange...
  27. ncbi request reprint Circulating endothelial cells: a novel marker of endothelial damage
    Uta Erdbruegger
    Department of Medicine, Division of Nephrology, Hannover Medical School, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    Clin Chim Acta 373:17-26. 2006
    ..In summary, CECs must now be regarded as a sensitive and specific marker of endothelial damage. We emphasize that use of CECs in a clinical setting is on the horizon and pathogenetic clues may also be obtained...
  28. ncbi request reprint Circulating endothelial cells: a marker of vascular damage in patients with preeclampsia
    Magdalena Grundmann
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Am J Obstet Gynecol 198:317.e1-5. 2008
    ..We tested the hypothesis that circulating endothelial cells (CECs) are elevated in preeclampsia and that cell numbers correlate with disease activity...
  29. ncbi request reprint Engulfment of apoptotic cells by microvascular endothelial cells induces proinflammatory responses
    Torsten Kirsch
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Blood 109:2854-62. 2007
    ..These data indicate that CECs are not only markers of vascular damage but may induce proinflammatory signals in the endothelium...
  30. ncbi request reprint Circulating endothelial cells and vasculitis
    Marion Haubitz
    Division of Nephrology, Department of Medicine, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Intern Med 43:660-7. 2004
    ..Circulating endothelial cells may complement, rather than replace, conventional markers of disease activity. The ultimate aim of our studies may thus be a panel of various laboratory markers for systemic vasculitis...
  31. ncbi request reprint In-center intermittent peritoneal dialysis: retrospective ten-year single-center experience with thirty consecutive patients
    Alexander Woywodt
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Perit Dial Int 28:518-26. 2008
    ..Complications, frequency of hospital admission, and survival are often claimed to be dismal although current data are lacking...
  32. ncbi request reprint Vascular endothelial damage and repair in antineutrophil cytoplasmic antibody-associated vasculitis
    K de Groot
    Hannover Medical School, Hannover, Germany
    Arthritis Rheum 56:3847-53. 2007
    ..Bone marrow-derived endothelial progenitor cells (EPCs) are thought to play a pivotal role in the regeneration of damaged endothelium. The aim of this study was to investigate whether EPCs are involved in vascular repair in AAV...
  33. pmc Identification and validation of urinary biomarkers for differential diagnosis and evaluation of therapeutic intervention in anti-neutrophil cytoplasmic antibody-associated vasculitis
    Marion Haubitz
    Department of Nephrology, Hannover Medical School, D 30625 Hannover, Germany
    Mol Cell Proteomics 8:2296-307. 2009
    ....
  34. ncbi request reprint Serologic evidence of Chlamydia pneumoniae infection as a long-term predictor of cardiovascular death in renal transplant recipients
    Marion Haubitz
    Department of Nephrology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Transplantation 77:1517-21. 2004
    ..So far, no such data have been available in renal transplant recipients...
  35. ncbi request reprint No association of G-463A myeloperoxidase gene polymorphism with MPO-ANCA-associated vasculitis
    Anette Fiebeler
    Department of Nephrology, Medical School Hannover, D 30623 Hannover, Germany
    Nephrol Dial Transplant 19:969-71. 2004
    ..As the A allele of the G-463A MPO gene polymorphism is associated with diminished activity of MPO, it is conceivable that the presence of this allele protects against MPO-ANCA-associated vasculitis...
  36. ncbi request reprint Mechanisms and markers of vascular damage in ANCA-associated vasculitis
    Marion Haubitz
    Division of Nephrology, Department of Medicine, Hannover Medical School, Hannover, Germany
    Autoimmunity 42:605-14. 2009
    ..Here, we review mechanisms and markers of endothelial damage and repair in ANCA-associated vasculitis and put these findings into perspective...
  37. doi request reprint Diagnostic role of endothelial microparticles in vasculitis
    U Erdbruegger
    Division of Nephrology, Department of Medicine, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Rheumatology (Oxford) 47:1820-5. 2008
    ..More recently, endothelial microparticles (EMPs) were found to be increased in active childhood vasculitis. The role of EMP in adult AAV and the relationship between EMP and CEC is unclear...
  38. pmc Smoking habits in patients diagnosed with ANCA associated small vessel vasculitis
    M Haubitz
    Department of Nephrology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Ann Rheum Dis 64:1500-2. 2005
    ..To study the prevalence of smoking at onset of symptoms in patients with small vessel vasculitis associated with antineutrophil cytoplasmic antibodies (ANCA)...
  39. doi request reprint Serum leptin and ghrelin correlate with disease activity in ANCA-associated vasculitis
    P Kümpers
    Department of Nephrology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Rheumatology (Oxford) 47:484-7. 2008
    ..To study serum levels of leptin and ghrelin in ANCA-associated vasculitis (AAV)...
  40. ncbi request reprint Necrotizing small-vessel vasculitis confined to the uterine cervix
    A Woywodt
    Department of Nephrology, Franz Volhard Clinic, Charité Campus Berlin Buch, Humboldt University, Germany
    Semin Arthritis Rheum 29:368-72. 2000
    ..To report our experience with five cases of apparently isolated small-vessel vasculitis of the uterine cervix...
  41. ncbi request reprint Cardiopulmonary auscultation: duo for strings--Opus 99
    A Woywodt
    Franz Volhard Clinic, Berlin, Germany
    Arch Intern Med 159:2477-9. 1999
    ..Cardiopulmonary auscultation should receive more emphasis in the medical school curriculum and clinical training...
  42. ncbi request reprint Efficiency of high-flux hemodialysis in the treatment of valproic acid intoxication
    J T Kielstein
    Division of Nephrology, Department of Clinical Chemistry, Medical School Hannover, Hannover, Germany
    J Toxicol Clin Toxicol 41:873-6. 2003
    ..Concentration of VPA in the total collected dialysate were measured...
  43. ncbi request reprint Vertebral osteomyelitis and endocarditis of a pacemaker lead due to Granulicatella (Abiotrophia) adiacens
    O Rosenthal
    Division of Nephrology, University of Hannover School of Medicine, Hannover, Germany
    Infection 30:317-9. 2002
    ..adiacens was made and the patient improved with bed rest and medical treatment alone. Granulicatella ssp. should always be part of the differential diagnosis of fastidious bacteria in vertebral osteomyelitis and endocarditis...
  44. pmc Acute liver failure: a message found under the skin
    M Meier
    Division of Nephrology, Hanover Medical School, Germany
    Postgrad Med J 81:269-70. 2005
    ..The patient recovered with maximum supportive care after surgical removal but without liver transplantation. This case illustrates that only meticulous history taking will disclose the sometimes bewildering causes of acute liver failure...
  45. doi request reprint Travel-associated acquisition of hepatitis C-- implications for the renal transplant waiting list
    Dominic Parsons
    Nephrol Dial Transplant 23:2104; author reply 2104-5. 2008
  46. ncbi request reprint Immunomagnetic isolation and FACS--competing techniques for the enumeration of circulating endothelial cells
    Alexander Woywodt
    Thromb Haemost 96:1-2. 2006
  47. ncbi request reprint Circulating endothelial cells: life, death, detachment and repair of the endothelial cell layer
    Alexander Woywodt
    Nephrol Dial Transplant 17:1728-30. 2002
  48. ncbi request reprint Circulating endothelial cells. Biomarker of vascular disease
    Andrew D Blann
    Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, B18 7QH, UK
    Thromb Haemost 93:228-35. 2005
    ..The objective of the present communication is to condense existing data on CECs, briefly compare them with progenitor cells, and summarise possible mechanism(s) by which they may contribute to vascular pathology...
  49. ncbi request reprint Detection of circulating endothelial cells: CD146-based magnetic separation enrichment or flow cytometric assay?
    Francoise Dignat-George
    J Clin Oncol 25:e1-2; author reply e3-5. 2007
  50. ncbi request reprint Letter by Kielstein et al regarding article, "High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid"
    Jan T Kielstein
    Circulation 115:e450-1; author reply e451. 2007
  51. ncbi request reprint A wild zebra chase
    Alexander Woywodt
    FASN, Renal Unit, Lancashire Teaching Hospitals NHS Trust, Royal Preston Hospital, Sharoe Green Lane, Preston, PR2 9HT, UK
    Nephrol Dial Transplant 22:3074-7. 2007
  52. pmc Should eponyms be abandoned? Yes
    Alexander Woywodt
    Renal Unit, Lancashire Teaching Hospitals NHS Trust, Preston, Lancashire PR2 9HT
    BMJ 335:424. 2007
  53. ncbi request reprint Circulating endothelial cells in renal disease: markers and mediators of vascular damage
    Alexander Woywodt
    Nephrol Dial Transplant 23:7-10. 2008