Hans Worthmann

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. doi request reprint Educational campaign on stroke in an urban population in Northern Germany: influence on public stroke awareness and knowledge
    Hans Worthmann
    Department of Neurology, Hannover Medical School, Carl Neuberg Strasse 1, Hannover, Germany
    Int J Stroke 8:286-92. 2013
  2. pmc Monocyte chemotactic protein-1 as a potential biomarker for early anti-thrombotic therapy after ischemic stroke
    Hans Worthmann
    Department of Neurology, Hannover Medical School, Carl Neuberg Str 1, Hannover 30625, Germany E Mails H W R D W G E
    Int J Mol Sci 13:8670-8. 2012
  3. doi request reprint The temporal profile of inflammatory markers and mediators in blood after acute ischemic stroke differs depending on stroke outcome
    H Worthmann
    Department of Neurology, Medical School of Hannover, Hannover, Germany
    Cerebrovasc Dis 30:85-92. 2010
  4. doi request reprint Linking infection and inflammation in acute ischemic stroke
    H Worthmann
    Department of Neurology, Medical School of Hannover, Germany
    Ann N Y Acad Sci 1207:116-22. 2010
  5. ncbi request reprint High plasma dimethylarginine levels are associated with adverse clinical outcome after stroke
    Hans Worthmann
    Department of Neurology, Hannover Medical School, Hannover, Germany
    J Atheroscler Thromb 18:753-61. 2011
  6. pmc Association of dimethylarginines and mediators of inflammation after acute ischemic stroke
    Shufen Chen
    Department of Neurology, Hannover Medical School, Carl Neuberg Strasse 1, Hannover 30623, Germany
    J Neuroinflammation 9:251. 2012
  7. doi request reprint Temporal pattern of cytotoxic edema in the perihematomal region after intracerebral hemorrhage: a serial magnetic resonance imaging study
    Na Li
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Stroke 44:1144-6. 2013
  8. doi request reprint Circulating endothelial cells as potential diagnostic biomarkers in primary central nervous system vasculitis
    Milani Deb
    Department of Neurology, Hannover Medical School, Carl Neuberg Str 1, Hannover D 30625, Germany
    J Neurol Neurosurg Psychiatry 84:732-4. 2013
  9. doi request reprint Growth differentiation factor 15 plasma levels and outcome after ischemic stroke
    Hans Worthmann
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Cerebrovasc Dis 32:72-8. 2011
  10. doi request reprint Asymmetric dimethylarginine in response to recombinant tissue-type plasminogen activator and erythropoietin in acute stroke
    Hans Worthmann
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Stroke 44:2128-33. 2013

Collaborators

Detail Information

Publications19

  1. doi request reprint Educational campaign on stroke in an urban population in Northern Germany: influence on public stroke awareness and knowledge
    Hans Worthmann
    Department of Neurology, Hannover Medical School, Carl Neuberg Strasse 1, Hannover, Germany
    Int J Stroke 8:286-92. 2013
    ..Public stroke awareness and knowledge may be supportive for stroke prevention and emergency care-seeking behavior after the acute event, which is highly important for early treatment onset...
  2. pmc Monocyte chemotactic protein-1 as a potential biomarker for early anti-thrombotic therapy after ischemic stroke
    Hans Worthmann
    Department of Neurology, Hannover Medical School, Carl Neuberg Str 1, Hannover 30625, Germany E Mails H W R D W G E
    Int J Mol Sci 13:8670-8. 2012
    ..However, MCP-1 may be a useful biomarker for deciding on early stroke therapy, as patients with high MCP-1 at baseline appear to benefit from early treatment with ASA + ER-DP...
  3. doi request reprint The temporal profile of inflammatory markers and mediators in blood after acute ischemic stroke differs depending on stroke outcome
    H Worthmann
    Department of Neurology, Medical School of Hannover, Hannover, Germany
    Cerebrovasc Dis 30:85-92. 2010
    ..The present study aimed to clarify the temporal dynamics of discrete inflammatory markers/mediators for future mechanism-targeting anti-inflammatory strategies in ischemic brain damage...
  4. doi request reprint Linking infection and inflammation in acute ischemic stroke
    H Worthmann
    Department of Neurology, Medical School of Hannover, Germany
    Ann N Y Acad Sci 1207:116-22. 2010
    ..Thus, sequential dynamics of early inflammation must be considered in the development of both mechanism-targeting anti-inflammatory and anti-infectious treatment strategies in ischemic brain damage...
  5. ncbi request reprint High plasma dimethylarginine levels are associated with adverse clinical outcome after stroke
    Hans Worthmann
    Department of Neurology, Hannover Medical School, Hannover, Germany
    J Atheroscler Thromb 18:753-61. 2011
    ..We hypothesized that plasma dimethylarginine levels increase in the hyper-acute phase after ischemic stroke and that their time course is related to stroke outcome...
  6. pmc Association of dimethylarginines and mediators of inflammation after acute ischemic stroke
    Shufen Chen
    Department of Neurology, Hannover Medical School, Carl Neuberg Strasse 1, Hannover 30623, Germany
    J Neuroinflammation 9:251. 2012
    ..We sought to investigate the association between dimethylarginines and inflammatory mediators in patients with acute ischemic stroke...
  7. doi request reprint Temporal pattern of cytotoxic edema in the perihematomal region after intracerebral hemorrhage: a serial magnetic resonance imaging study
    Na Li
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Stroke 44:1144-6. 2013
    ..Knowledge about cytotoxic edema (CE) in intracerebral hemorrhage is still limited. We aimed to analyze its presence, temporal pattern, and prognostic meaning...
  8. doi request reprint Circulating endothelial cells as potential diagnostic biomarkers in primary central nervous system vasculitis
    Milani Deb
    Department of Neurology, Hannover Medical School, Carl Neuberg Str 1, Hannover D 30625, Germany
    J Neurol Neurosurg Psychiatry 84:732-4. 2013
    ..We hypothesise that CEC are also elevated in patients with active PCNSV and may contribute to the diagnosis...
  9. doi request reprint Growth differentiation factor 15 plasma levels and outcome after ischemic stroke
    Hans Worthmann
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Cerebrovasc Dis 32:72-8. 2011
    ..We hypothesized that the circulating levels of GDF-15 are increased and associated with neurological outcome in patients with ischemic stroke...
  10. doi request reprint Asymmetric dimethylarginine in response to recombinant tissue-type plasminogen activator and erythropoietin in acute stroke
    Hans Worthmann
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Stroke 44:2128-33. 2013
    ....
  11. doi request reprint Nitric oxide (NO) and asymmetric dimethylarginine (ADMA): their pathophysiological role and involvement in intracerebral hemorrhage
    Na Li
    Department of Neurology, Hannover Medical School, Germany
    Neurol Res 33:541-8. 2011
    ..This article aims to review the current knowledge about the role and metabolism of NO and ADMA. It will also address the role of the NO-NOS-ADMA pathway in ICH and delineate some questions that should be addressed by future studies...
  12. doi request reprint Quantitative MRI shows cerebral microstructural damage in hemolytic-uremic syndrome patients with severe neurological symptoms but no changes in conventional MRI
    Karin Weissenborn
    Clinic for Neurology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Neuroradiology 55:819-25. 2013
    ..This study aims to analyze if quantitative MRI is able to reveal cerebral pathological alterations invisible for conventional MRI...
  13. doi request reprint Anticoagulants affect matrix metalloproteinase 9 levels in blood samples of stroke patients and healthy controls
    Munir Rababah
    Department of Neurology, Hannover Medical School, Carl Neuberg Strase 1, 30623 Hannover, Germany
    Clin Biochem 45:483-9. 2012
    ..In clinical studies MMP-9 has been quantified by ELISA using differing protocols. We aimed to establish a valid protocol by evaluation of preanalytics...
  14. ncbi request reprint IL-4-induced priming of human intestinal mast cells for enhanced survival and Th2 cytokine generation is reversible and associated with increased activity of ERK1/2 and c-Fos
    Axel Lorentz
    Department of Gastroenterology, Hepatology, and Endocrinology, Medical School of Hannover, Germany
    J Immunol 174:6751-6. 2005
    ..In summary, our data show that the IL-4 effects on human intestinal mast cell functions are reversible and accompanied by an increased activity of ERK1/2 and c-Fos...
  15. doi request reprint Neurologic manifestations of E coli infection-induced hemolytic-uremic syndrome in adults
    Karin Weissenborn
    Hannover Medical School, Hannover, Germany
    Neurology 79:1466-73. 2012
    ..To describe the neurologic and neuroradiologic complications of Shiga toxin producing Escherichia coli infection (STEC)-associated hemolytic-uremic syndrome (HUS) in adults...
  16. pmc Circulating microRNAs in patients with Shiga-Toxin-producing E. coli O104:H4 induced hemolytic uremic syndrome
    Johan M Lorenzen
    Institute of Molecular and Translational Therapeutic Strategies IMTTS, Hannover, Germany
    PLoS ONE 7:e47215. 2012
    ..MicroRNAs are small ribonucleotides orchestrating gene expression. We tested whether circulating microRNAs in serum of HUS patients during the 2011 epidemics are altered in this patient cohort and related to clinical manifestations...
  17. doi request reprint Hepatic encephalopathy after treatment with temozolomide
    Annemarie Goldbecker
    Department of Neurology and Clinical Neurophysiology, Hannover Medical School, 30623 Hannover, Germany
    J Neurooncol 103:163-6. 2011
    ..Furthermore, new side effects of drugs have to be considered. At least this case might lead to a closer monitoring of liver enzymes during temozolomide therapy...
  18. doi request reprint Diagnostic accuracy of plasma glial fibrillary acidic protein for differentiating intracerebral hemorrhage and cerebral ischemia in patients with symptoms of acute stroke
    Christian Foerch
    Department of Neurology, Goethe University, Frankfurt am Main, Germany
    Clin Chem 58:237-45. 2012
    ..In this study the diagnostic accuracy of plasma GFAP was determined in a prospective multicenter approach...
  19. doi request reprint Hepatitis C virus infection and the brain
    Karin Weissenborn
    Department of Neurology, Hannover Medical School, 30623 Hannover, Germany
    Metab Brain Dis 24:197-210. 2009
    ..Therefore, the Trojan horse hypothesis emerged: HCV-infected mononuclear blood cells enter the brain, enabling the virus to reside within the brain (probably in microglia) and to infect brain cells, especially astrocytes...