Doan Dh Tran
Affiliation: Hannover Medical School
Niehus S, Tran D, Mischak M, Koch A. Colony-stimulating factor-1 receptor provides a growth advantage in epithelial cancer cell line A431 in the presence of epidermal growth factor receptor inhibitor gefitinib. Cell Signal. 2018;51:191-198 pubmed publisher
..These data suggest that CSF-1R has the potential to reduce sensitivity to gefitinib and may be involved in resistance development. ..
Koch A, Saran S, Tran D, Klebba FÃ¤rber S, Thiesler H, Sewald K, et al
. Murine precision-cut liver slices (PCLS): a new tool for studying tumor microenvironments and cell signaling ex vivo. Cell Commun Signal. 2014;12:73 pubmed publisher
..This method may also prove useful for identification of genes in liver-resident cells that support cancer invasion by using PCLS from transgenic liver. ..
Saran S, Tran D, Klebba Färber S, Morán Losada P, Wiehlmann L, Koch A, et al
. THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier. BMC Cell Biol. 2013;14:51 pubmed publisher
..These data imply that THOC5 may be a useful tool for studying intestinal stem cells, for modifying the differentiation processes and for cancer therapy. ..