Teruko Tamura

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. pmc An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5
    Sheetal Ramachandran
    Institut fur Biochemie, OE4310, Medizinische Hochschule Hannover, D 30623 Hannover, Germany
    RNA 17:1957-66. 2011
  2. ncbi Transcriptional regulation of immediate-early gene response by THOC5, a member of mRNA export complex, contributes to the M-CSF-induced macrophage differentiation
    D D H Tran
    Institut fuer Biochemie, OE4310, Medizinische Hochschule Hannover, Carl Neuberg Street 1, Hannover D 30623, Germany
    Cell Death Dis 4:e879. 2013
  3. doi THOC5, a member of the mRNA export complex: a novel link between mRNA export machinery and signal transduction pathways in cell proliferation and differentiation
    Doan D H Tran
    Institut fuer Biochemie, OE4310, Medizinische Hochschule Hannover, Carl Neuberg Str, 1, D 30623, Hannover, Germany
    Cell Commun Signal 12:3. 2014
  4. ncbi THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier
    Shashank Saran
    Institut fuer Biochemie, Medizinische Hochschule Hannover, OE4310 Carl Neuberg Str, 1, Hannover D 30623, Germany
    BMC Cell Biol 14:51. 2013
  5. ncbi The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading
    Alexandra Koch
    Institut fur Biochemie, Medizinische Hochschule Hannover, OE 4310, Carl Neuberg Str 1, Hannover D 30623, Germany
    Oncogene 24:3436-47. 2005
  6. pmc Identification of mRNAs that are spliced but not exported to the cytoplasm in the absence of THOC5 in mouse embryo fibroblasts
    Anuja Guria
    Institut fur Biochemie, OE4310, Medizinische Hochschule Hannover, D 30623 Hannover, Germany
    RNA 17:1048-56. 2011
  7. pmc THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo
    Annalisa Mancini
    Institut fuer Biochemie, OE4310, Medizinische Hochschule Hannover, Carl Neuberg Str, 1, D 30623 Hannover, Germany
    BMC Biol 8:1. 2010
  8. doi Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP)
    Omar El Bounkari
    Institut fuer Biochemie, OE4310 Medizinische Hochschule Hannover, Hannover, Germany
    FEBS Lett 583:13-8. 2009
  9. ncbi Tyrosine phosphorylation modulates binding preference to cyclin-dependent kinases and subcellular localization of p27Kip1 in the acute promyelocytic leukemia cell line NB4
    Christian Kardinal
    Pädiatrische Hämatologie und Onkologie, Medizinische Hochschule Hannover MHH, Hannover, Germany
    Blood 107:1133-40. 2006
  10. ncbi The M-CSF receptor substrate and interacting protein FMIP is governed in its subcellular localization by protein kinase C-mediated phosphorylation, and thereby potentiates M-CSF-mediated differentiation
    Annalisa Mancini
    Institut fur Biochemie, OE 4310, Medizinische Hochschule Hannover, Carl Neuberg Str 1, D 30623 Hannover, Germany
    Oncogene 23:6581-9. 2004

Collaborators

  • Annalisa Mancini
  • Priyanka Dutta
  • Andrea Hoffmann
  • Michael Kracht
  • Oliver Pabst
  • Robert Klopfleisch
  • Karl Welte
  • Alexandra Koch
  • Omar El Bounkari
  • Doan D H Tran
  • Sheetal Ramachandran
  • Anuja Guria
  • Christian Kardinal
  • Shashank Saran
  • D D H Tran
  • Doan Duy Hai Tran
  • Sabine Klebba-Faerber
  • Anthony D Whetton
  • Himpriya Chopra
  • Sabine Klebba-Färber
  • A J K Williamson
  • Patricia Moran-Losada
  • Lutz Wiehlmann
  • S Saran
  • A Koch
  • O Dittrich-Breiholz
  • A D Whetton
  • S Klebba-Färber
  • Hansjorg Hauser
  • Tomas Pieler
  • John R Griffiths
  • Maike Claussen
  • Dominique Tobias Brandt
  • Angelika Kardinal
  • Marc Dangers

Detail Information

Publications13

  1. pmc An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5
    Sheetal Ramachandran
    Institut fur Biochemie, OE4310, Medizinische Hochschule Hannover, D 30623 Hannover, Germany
    RNA 17:1957-66. 2011
    ..Furthermore, the treatment with KU55933 blocked DNA damage-induced THOC5mRNP complex dissociation, indicating that activation of ATM kinase suppresses the ability of THOC5 to bind to its target mRNAs...
  2. ncbi Transcriptional regulation of immediate-early gene response by THOC5, a member of mRNA export complex, contributes to the M-CSF-induced macrophage differentiation
    D D H Tran
    Institut fuer Biochemie, OE4310, Medizinische Hochschule Hannover, Carl Neuberg Street 1, Hannover D 30623, Germany
    Cell Death Dis 4:e879. 2013
    ..In conclusion, regulation of immediate-early gene response by THOC5, a member of mRNA export complex contributes to the M-CSF-induced macrophage differentiation. ..
  3. doi THOC5, a member of the mRNA export complex: a novel link between mRNA export machinery and signal transduction pathways in cell proliferation and differentiation
    Doan D H Tran
    Institut fuer Biochemie, OE4310, Medizinische Hochschule Hannover, Carl Neuberg Str, 1, D 30623, Hannover, Germany
    Cell Commun Signal 12:3. 2014
    ..The data from these studies also suggest that THOC5 may be a useful tool for studying stem cell biology, for modifying the differentiation processes and for cancer therapy. ..
  4. ncbi THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier
    Shashank Saran
    Institut fuer Biochemie, Medizinische Hochschule Hannover, OE4310 Carl Neuberg Str, 1, Hannover D 30623, Germany
    BMC Cell Biol 14:51. 2013
    ..Here we interrogate THOC5 function in cell differentiation beyond the hematopoietic system and study pathological changes caused by THOC5 deficiency...
  5. ncbi The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading
    Alexandra Koch
    Institut fur Biochemie, Medizinische Hochschule Hannover, OE 4310, Carl Neuberg Str 1, Hannover D 30623, Germany
    Oncogene 24:3436-47. 2005
    ....
  6. pmc Identification of mRNAs that are spliced but not exported to the cytoplasm in the absence of THOC5 in mouse embryo fibroblasts
    Anuja Guria
    Institut fur Biochemie, OE4310, Medizinische Hochschule Hannover, D 30623 Hannover, Germany
    RNA 17:1048-56. 2011
    ..Furthermore, Hsp70 mRNA was exported in the absence of THOC5 at 37°C, but not under heat shock condition (42°C), suggesting that THOC5 may be required for mRNA export under stress and/or upon signaling-induced conditions...
  7. pmc THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo
    Annalisa Mancini
    Institut fuer Biochemie, OE4310, Medizinische Hochschule Hannover, Carl Neuberg Str, 1, D 30623 Hannover, Germany
    BMC Biol 8:1. 2010
    ..THO complex (THOC) components are not essential for bulk poly (A)+ RNA export in higher eukaryotes, but for the nuclear export of subset of mRNAs, however, their exact role is still unclear...
  8. doi Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP)
    Omar El Bounkari
    Institut fuer Biochemie, OE4310 Medizinische Hochschule Hannover, Hannover, Germany
    FEBS Lett 583:13-8. 2009
    ..Furthermore, THOC7 lacking the FMIP binding site does not co-localize with FMIP, indicating that THOC7/FMIP interaction is required for nuclear localization of THOC7...
  9. ncbi Tyrosine phosphorylation modulates binding preference to cyclin-dependent kinases and subcellular localization of p27Kip1 in the acute promyelocytic leukemia cell line NB4
    Christian Kardinal
    Pädiatrische Hämatologie und Onkologie, Medizinische Hochschule Hannover MHH, Hannover, Germany
    Blood 107:1133-40. 2006
    ..Taken together, this report provides the first evidence that tyrosine phosphorylation of p27Kip1 plays a crucial role in binding to cdks and its subcellular localization. Moreover, both effects are mediated by application of G-CSF...
  10. ncbi The M-CSF receptor substrate and interacting protein FMIP is governed in its subcellular localization by protein kinase C-mediated phosphorylation, and thereby potentiates M-CSF-mediated differentiation
    Annalisa Mancini
    Institut fur Biochemie, OE 4310, Medizinische Hochschule Hannover, Carl Neuberg Str 1, D 30623 Hannover, Germany
    Oncogene 23:6581-9. 2004
    ..We conclude M-CSF-mediated activation of PKCalpha can potentiate FMIP action to initiate survival/differentiation signaling...
  11. ncbi The SH2-containing inositol 5-phosphatase (SHIP)-1 is implicated in the control of cell-cell junction and induces dissociation and dispersion of MDCK cells
    Annalisa Mancini
    Institut fur Biochemie, OE 4310, Medizinische Hochschule Hannover, Carl Neuberg Str 1, D 30623 Hannover, Germany
    Oncogene 21:1477-84. 2002
    ....
  12. pmc Identification of novel target genes of nerve growth factor (NGF) in human mastocytoma cell line (HMC-1 (V560G c-Kit)) by transcriptome analysis
    Priyanka Dutta
    Institut fuer Biochemie, OE4310, Medizinische Hochschule Hannover, Carl Neuberg Str, 1, D 30623 Hannover, Germany
    BMC Genomics 12:196. 2011
    ..However, the exact role of NGF in hematopoietic system is unclear. It is also not clear whether NGF mediated signals in hematopoietic cells are identical to those in neuronal cells...
  13. ncbi c-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-Fms
    Annalisa Mancini
    Institut fur Biochemie, OE 4310, Medizinische Hochschule Hannover, Carl Neuberg Str 1, D 30623 Hannover, Germany
    J Biol Chem 277:14635-40. 2002
    ..These data suggest that an indirect association of c-Cbl via multimeric complex induced a different signaling pathway from the pathway induced by c-Cbl direct interaction...