C G Stief

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. ncbi request reprint Sustained efficacy and tolerability with vardenafil over 2 years of treatment in men with erectile dysfunction
    C Stief
    Department of Urology, Medizinische Hochschule, Hannover, Germany
    Int J Clin Pract 58:230-9. 2004
  2. ncbi request reprint Smooth muscle electromyography
    C G Stief
    Department of Urology, Urologische Klinik, Hannover, Germany
    Urol Clin North Am 28:259-68, viii. 2001
  3. ncbi request reprint Phosphodiesterase isoenzymes as pharmacological targets in the treatment of male erectile dysfunction
    S Uckert
    Hannover Medical School, Department of Urology, Germany
    World J Urol 19:14-22. 2001
  4. ncbi request reprint A simple and reliable continent bladder stoma constructed from bladder wall
    Christian G Stief
    Urologische Klinik, MHH, 30623 Hannover, Germany
    World J Urol 21:144-6. 2003
  5. ncbi request reprint Long-term follow-up after surgery for advanced colorectal carcinoma involving the urogenital tract
    Christian G Stief
    Department of Urology, Urologische Klinik, MHH, D 30623 Hannover, Germany
    Eur Urol 41:546-50. 2002
  6. ncbi request reprint Is there a common pathophysiology of erectile dysfunction and how does this relate to new pharmacotherapies?
    C G Stief
    Urologische Klinik, Medizinische Hochschule Hannover, Germany
    Int J Impot Res 14:S11-6. 2002
  7. ncbi request reprint Interdisciplinary abdomino-urological surgery for advanced colorectal carcinoma involving the urogenital tract
    C G Stief
    Department of Urology and Abdominal and Transplant Surgery, MHH Hannover, Germany
    BJU Int 89:496-503. 2002
  8. ncbi request reprint Central mechanisms of erectile dysfunction: what a clinician may want to know
    C G Stief
    Medical School Hannover, Department of Urology, Hannover, Germany
    Int J Impot Res 15:S3-6. 2003
  9. ncbi request reprint Apical dissection during radical retropubic prostatectomy without ligature
    Christian G Stief
    Urologische Klinik, MHH, 30623 Hannover, Germany
    World J Urol 21:139-43. 2003
  10. ncbi request reprint Systemic and cavernous plasma levels of endothelin (1-21) during different penile conditions in healthy males and patients with erectile dysfunction
    A J Becker
    Hannover Medical School, Department of Urology, Germany
    World J Urol 19:267-71. 2001

Detail Information

Publications116 found, 100 shown here

  1. ncbi request reprint Sustained efficacy and tolerability with vardenafil over 2 years of treatment in men with erectile dysfunction
    C Stief
    Department of Urology, Medizinische Hochschule, Hannover, Germany
    Int J Clin Pract 58:230-9. 2004
    ..Most treatment-emergent events were mild and transient with no cardiovascular safety concerns. These results support the long-term efficacy, reliability and tolerability of vardenafil 10 and 20 mg in men with ED...
  2. ncbi request reprint Smooth muscle electromyography
    C G Stief
    Department of Urology, Urologische Klinik, Hannover, Germany
    Urol Clin North Am 28:259-68, viii. 2001
    ..This article addresses smooth muscle physiology, electromechanical and pharmacomechanical coupling, computed-based interpretations, and the role of electromyography in the diagnosis of erectile dysfunction...
  3. ncbi request reprint Phosphodiesterase isoenzymes as pharmacological targets in the treatment of male erectile dysfunction
    S Uckert
    Hannover Medical School, Department of Urology, Germany
    World J Urol 19:14-22. 2001
    ..Further research will possibly allow identification of diagnostic tools for erectile dysfunction and of even more selective drugs in its therapy...
  4. ncbi request reprint A simple and reliable continent bladder stoma constructed from bladder wall
    Christian G Stief
    Urologische Klinik, MHH, 30623 Hannover, Germany
    World J Urol 21:144-6. 2003
    ..Five of our patients now have a minimum follow-up of 11 months (mean 17 months). All are continent with a bladder capacity between 250 and 560 ml. In two, stomal stenosis at the skin level required epifascial stomal revision...
  5. ncbi request reprint Long-term follow-up after surgery for advanced colorectal carcinoma involving the urogenital tract
    Christian G Stief
    Department of Urology, Urologische Klinik, MHH, D 30623 Hannover, Germany
    Eur Urol 41:546-50. 2002
    ..Advanced colorectal carcinomas frequently involve the urogenital tract. In the following we evaluate the long-term survival after radical surgical extirpation and the prognostic significance of involvement of specific urological organs...
  6. ncbi request reprint Is there a common pathophysiology of erectile dysfunction and how does this relate to new pharmacotherapies?
    C G Stief
    Urologische Klinik, Medizinische Hochschule Hannover, Germany
    Int J Impot Res 14:S11-6. 2002
    ..However, some factors will render all imaginable forms of pharmacological options totally inefficient, thus necessitating forms of treatment other than pharmacotherapy...
  7. ncbi request reprint Interdisciplinary abdomino-urological surgery for advanced colorectal carcinoma involving the urogenital tract
    C G Stief
    Department of Urology and Abdominal and Transplant Surgery, MHH Hannover, Germany
    BJU Int 89:496-503. 2002
  8. ncbi request reprint Central mechanisms of erectile dysfunction: what a clinician may want to know
    C G Stief
    Medical School Hannover, Department of Urology, Hannover, Germany
    Int J Impot Res 15:S3-6. 2003
    ..This unique central mode of action of apo SL has thus proved efficacious in approximately 70% of ED patients although persistence may be required to produce a robust effect for the maximum number of patients...
  9. ncbi request reprint Apical dissection during radical retropubic prostatectomy without ligature
    Christian G Stief
    Urologische Klinik, MHH, 30623 Hannover, Germany
    World J Urol 21:139-43. 2003
    ..However, long-term follow-up and multicenter studies will show if this modification results in equally effective cancer control and equivalent functional results compared to the standard approach...
  10. ncbi request reprint Systemic and cavernous plasma levels of endothelin (1-21) during different penile conditions in healthy males and patients with erectile dysfunction
    A J Becker
    Hannover Medical School, Department of Urology, Germany
    World J Urol 19:267-71. 2001
    ....
  11. ncbi request reprint Possible role of bradykinin and angiotensin II in the regulation of penile erection and detumescence
    A J Becker
    Department of Urology, Hannover Medical School, Hannover, Germany
    Urology 57:193-8. 2001
    ....
  12. doi request reprint Prediction of outcome in patients with urothelial carcinoma of the bladder following radical cystectomy using artificial neural networks
    A Buchner
    Department of Urology, Ludwig Maximilians University Munich, Grosshadern, Marchioninistr 15, 81377 Munich, Germany
    Eur J Surg Oncol 39:372-9. 2013
    ..We evaluated the ability of artificial neural networks (ANN) to perform risk stratification in UCB patients based on common parameters available at the time of RC...
  13. ncbi request reprint Cavernous and systemic testosterone plasma levels during different penile conditions in healthy males and patients with erectile dysfunction
    A J Becker
    Department of Urology, Hannover Medical School, Hannover, Germany
    Urology 58:435-40. 2001
    ....
  14. ncbi request reprint Initial clinical experience with the selective phosphodiesterase-I isoenzyme inhibitor vinpocetine in the treatment of urge incontinence and low compliance bladder
    M C Truss
    Department of Urology, Medizinische Hochschule Hannover, Germany
    World J Urol 18:439-43. 2000
    ..Although these initial data are preliminary, they represent the first evidence that isoenzyme-selective PDE inhibition may be a novel approach to the treatment of lower urinary tract disorders...
  15. pmc Sorafenib after combination therapy with gemcitabine plus doxorubicine in patients with sarcomatoid renal cell carcinoma: a prospective evaluation
    Michael Staehler
    Department of Urology, University of Munich, Klinikum Grosshadern, Marchioninistr 15, 81377 Munchen, Germany
    Eur J Med Res 15:287-91. 2010
    ..We carried out a prospective, open-label study to investigate the efficacy and safety of sorafenib in patients after GD failure in sarcomatoid RCC...
  16. pmc Comparison of guideline recommendations with daily practice in patients with renal cell carcinoma
    B Schlenker
    Department of Urology, University Hospital Grosshadern, Ludwig Maximilians University Munich, Munich, Germany
    Eur J Med Res 15:253-7. 2010
    ..OBJECTIVES AND AIMS: To compare guideline recommendations with daily practice patterns in a German patient cohort with renal cell carcinoma...
  17. ncbi request reprint Phosphodiesterase 1 inhibition in the treatment of lower urinary tract dysfunction: from bench to bedside
    M C Truss
    Urologische Klinik, Medizinische Hochschule, Hannover, Germany
    World J Urol 19:344-50. 2001
    ..e. isoenzyme-selective PDE inhibition is a novel approach which possibly avoids the limitations of anticholinergic therapy in patients with lower urinary tract dysfunction...
  18. ncbi request reprint Pilot study of the transdermal application of testosterone gel to the penile skin for the treatment of hypogonadotropic men with erectile dysfunction
    D Schultheiss
    Department of Urology, Medizinische Hochschule Hannover, Germany
    World J Urol 18:431-5. 2000
    ..We therefore suggest that future double-blind and placebo-controlled studies should be designed for a minimum of 3 months. Testosterone gel may be a cost effective form of androgen administration...
  19. ncbi request reprint Central effects of sildenafil (Viagra) on auditory selective attention and verbal recognition memory in humans: a study with event-related brain potentials
    D Schultheiss
    Department of Urology, Hannover Medical School, Germany
    World J Urol 19:46-50. 2001
    ..No overt effects on behavior were observed. Nevertheless, the data reveal CNS-effects of sildenafil necessitating further studies...
  20. pmc Inhibition of adrenergic human prostate smooth muscle contraction by the inhibitors of c-Jun N-terminal kinase, SP600125 and BI-78D3
    F Strittmatter
    Department of Urology, University of Munich, Munich, Germany
    Br J Pharmacol 166:1926-35. 2012
    ..Models of α(1)-adrenoceptor-mediated prostate smooth muscle contraction should include this JNK-dependent mechanism...
  21. ncbi request reprint Systemic and cavernosal plasma levels of endothelin (1-21) during different penile conditions in healthy males and patients with erectile dysfunction
    A J Becker
    Hannover Medical School, Department of Urology, Germany
    World J Urol 19:371-6. 2001
    ....
  22. ncbi request reprint Plasma levels of cyclic guanosine-3',5'-monophosphate in the cavernous and systemic blood of healthy males during different functional conditions of the penis
    A J Becker
    Hannover Medical School, Department of Urology, Hannover, Germany
    Urol Res 29:366-70. 2001
    ..Thus, we conclude that the quantification of cGMP is of no use in the evaluation of the physiologic mechanisms of penile erection in vivo...
  23. doi request reprint Efficacy of retrograde ureteropyeloscopic holmium laser lithotripsy for intrarenal calculi >2 cm
    M J Bader
    Department of Urology, University Hospital Großhadern, Ludwig Maximilians University Munich, Marchioninistr 15, 81377, Munich, Germany
    Urol Res 38:397-402. 2010
    ....
  24. ncbi request reprint Plasma levels of angiotensin II during different penile conditions in the cavernous and systemic blood of healthy men and patients with erectile dysfunction
    A J Becker
    Department of Urology, Hannover Medical School, Hannover, Germany
    Urology 58:805-10. 2001
    ..Since the tissue and plasma levels of Ang II are regulated by the activity of angiotensin-converting enzyme, there might be a rationale for the use of angiotensin-converting enzyme inhibitors in the treatment of vasculogenic ED...
  25. ncbi request reprint Gene expression of the phosphodiesterases 3A and 5A in human corpus cavernosum penis
    A Kuthe
    Hannover Medical School, Department of Urology and b Lower Saxony Institute for Peptide Research, Germany
    Eur Urol 38:108-14. 2000
    ....
  26. doi request reprint Predictive factors for urinary retention following kidney transplantation in male patients
    C Gratzke
    Department of Urology, University of Munich, Munich, Germany
    Scand J Urol Nephrol 46:44-7. 2012
    ..Urinary retention frequently occurs in patients after kidney transplantation. This study aimed to identify predictive factors for urinary retention requiring transurethral resection of the prostate (TURP) following kidney transplantation...
  27. ncbi request reprint Molecular biological characterization of phosphodiesterase 3A from human corpus cavernosum
    A Kuthe
    Hannover Medical School, Department of Urology, Germany
    Chem Biol Interact 119:593-8. 1999
    ..The data obtained indicate that neither the expression levels nor the sequence deviations of PDE3A are the main reasons for erectile dysfunction in men...
  28. ncbi request reprint [Drug therapy of erectile dysfunction--the current status]
    D Schultheiss
    Klinik für Urologie und Kinderurologie, Medizinische Hochschule, Hannover
    Urologe A 42:1322-9. 2003
    ..The intra-cavernosal pharmacotherapy with PGE(1) is considered the gold standard when oral therapies do not work or can not be used...
  29. ncbi request reprint Growth hormone, somatomedins and men's health
    A J Becker
    Department of Urology, Hannover Medical School, Hannover, Germany
    Aging Male 5:258-62. 2002
    ..In an ongoing study, we are evaluating whether growth hormone and somatomedins might be of importance in the regulation of male sexual performance, including penile erection...
  30. ncbi request reprint Congenital and acquired penile deviation treated with the essed plication method
    D Schultheiss
    Department of Urology, Hannover Medical School, Hannover, Germany
    Eur Urol 38:167-71. 2000
    ..To evaluate our results with the Essed procedure for the correction of penile curvature, either congenital or due to Peyronie's disease, and compare it with the data from the literature, both for the Essed and the Nesbit procedure...
  31. ncbi request reprint Characterization and functional relevance of cyclic nucleotide phosphodiesterase isoenzymes of the human prostate
    S Uckert
    Department of Urology, Hannover Medical School, Hannover, Germany
    J Urol 166:2484-90. 2001
    ..These studies support the possible use of inhibitors of PDE 4 and 5 for treating urinary obstruction secondary to benign prostatic hyperplasia...
  32. doi request reprint External validation of disease-free survival at 2 or 3 years as a surrogate and new primary endpoint for patients undergoing radical cystectomy for urothelial carcinoma of the bladder
    P Nuhn
    Department of Urology, Klinikum der Universität München Campus Großhadern, Ludwig Maximilians Universitat, Marchioninistr 15, 81377 Munich, Germany
    Eur J Surg Oncol 38:637-42. 2012
    ....
  33. pmc Management of pelvic lymphoceles after radical prostatectomy: a multicentre community based study
    W Y Khoder
    Department of Urology, University Hospital Munich Grosshadern, Ludwig Maximilians University Munich, Germany
    Eur J Med Res 16:280-4. 2011
    ..Pelvic lymphoceles (LC) following radical prostatectomy (LC-RP) have an incidence up to 27%. LC-managements constitute 50% of surgical interventions performed in post-RP patients...
  34. pmc Minimizing complications during retropubic radical prostatectomy - Is ureteral stenting necessary?
    B Schlenker
    Department of Urology, University Hospital Grosshadern, Ludwig Maximilians University Munich, Germany
    Eur J Med Res 15:121-3. 2010
    ..We evaluated our bladder neck preserving technique at radical prostatectomy with regard to ureteric injuries...
  35. ncbi request reprint [Biological vascularized matrix (BioVaM): a new method for solving the perfusion problems in tissue engineering]
    D Schultheiss
    Klinik und Poliklinik für Urologie und Kinderurologie, Medizinische Hochschule Hannover
    Urologe A 43:1223-8. 2004
    ..First promising short term implantation experiments using a porcine model for the evaluation of early graft perfusion after vascular anastomosis are presented...
  36. ncbi request reprint [Tissue engineering in urology. Status in Germany in 2004]
    D Schultheiss
    Klinik und Poliklinik für Urologie und Kinderurologie, Medizinische Hochschule Hannover
    Urologe A 43:1198-9. 2004
  37. ncbi request reprint Androgen and estrogen receptors in the human corpus cavernosum penis: immunohistochemical and cell culture results
    Dirk Schultheiss
    Department of Urology and Pediatric Urology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    World J Urol 21:320-4. 2003
    ..This is supported by the observed effect of testosterone and dihydrotestosterone on cell count and endothelial cell metabolism in our cell culture system. The role of estrogens remains unclear...
  38. ncbi request reprint Interactions between cGMP- and cAMP-pathways are involved in the regulation of penile smooth muscle tone
    Stefan Uckert
    Hanover Medical School, Department of Urology, 30625 Hannover, Germany
    World J Urol 22:261-6. 2004
    ..The immunoreactivity specific for PDE3, PDE4, PDE4A and PKA registered in HCC section is also in support of an important role for the cAMP/PKA-system for penile smooth muscle function...
  39. ncbi request reprint Immunohistochemical distribution of cyclic GMP-dependent protein kinase-1 in human prostate tissue
    Eginhard S Waldkirch
    Hannover Medical School, Department of Urology, 30625 Hannover, Germany
    Eur Urol 52:495-501. 2007
    ..The aim of the present study was to evaluate, by means of immunohistochemistry and Western blot analysis, the expression and localization of cGKI isoforms in relation to smooth muscle alpha-actin and cGMP in the human prostate...
  40. ncbi request reprint Functional tissue engineering of autologous tunica albuginea: a possible graft for Peyronie's disease surgery
    Dirk Schultheiss
    Department of Urology and Pediatirc Urology and Tissue Engineering Network, Hannover Medical School, Germany
    Eur Urol 45:781-6. 2004
    ..The aim of the present study was to generate a tissue engineered type of mechanically stable graft suitable for surgical replacement of the tunica albuginea penis...
  41. ncbi request reprint Biological vascularized matrix for bladder tissue engineering: matrix preparation, reseeding technique and short-term implantation in a porcine model
    Dirk Schultheiss
    Departments of Urology and Pediatric Urology, Hannover Medical School, Cark Neuberg Strasse 1, D 30625 Hannover, Germany
    J Urol 173:276-80. 2005
    ..We generated a vascularized, autologous, reseeded bladder substitute and evaluated immediate vascularization and perfusion of the graft after implantation to the recipient organism in a porcine model...
  42. ncbi request reprint Cyclic AMP-specific and cyclic GMP-specific phosphodiesterase isoenzymes in human cavernous arteries--immunohistochemical distribution and functional significance
    Eginhard Waldkirch
    Department of Urology, Hannover Medical School, 30625, Hannover, Germany
    World J Urol 23:405-10. 2005
    ....
  43. doi request reprint Systemic and cavernous plasma levels of neuropeptide Y during sexual arousal in healthy males
    S Uckert
    Hannover Medical School, Division of Surgery, Department of Urology and Urological Oncology, Hannover, Germany
    Andrologia 44:307-11. 2012
    ..4 ± 27, T: 65.8 ± 19, R: 59.6 ± 25, D: 67.6 ± 29.3). Our findings are in favour of the hypothesis that NPY could contribute to the maintenance of the resting state of cavernous smooth muscle...
  44. ncbi request reprint In vitro construction of urinary bladder wall using porcine primary cells reseeded on acellularized bladder matrix and small intestinal submucosa
    A I Gabouev
    Department of Urology, Leibniz Research Laboratories for Biotechnology and Artificial Organs, Hannover Medical School, Hannover, Germany
    Int J Artif Organs 26:935-42. 2003
    ..Our aim was to establish tissue engineering of an bioartificial bladder wall using primary cultures of porcine urothelial (pUC) and bladder smooth muscle cells (pSMC) to be reseeded on different acellular biological matrices...
  45. ncbi request reprint Immunocytochemical distribution of nitric oxide synthase in the human corpus cavernosum: an electron microscopical study using the tyramide signal amplification technique
    A Stanarius
    Department of Urology, Hannover Medical School, Germany
    Urol Res 29:168-72. 2001
    ..Our results counteract the hypothesis of the cavernous smooth muscle as a local source of NO and underline the importance of an intact endothelial function for penile erection and the contribution of eNOS to this process...
  46. ncbi request reprint Cyclic adenosine monophosphate and cyclic guanosine monophosphate-phosphodiesterase isoenzymes in human vagina: relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nerves
    Stefan Uckert
    Department of Urology, Hannover Medical School, Hannover, Germany
    Urology 65:604-10. 2005
    ..Nitric oxide and VIP, mediating biologic signals through cGMP and cAMP, have been assumed to be involved in the control of vaginal smooth muscle...
  47. ncbi request reprint Isolation of primary endothelial and stromal cell cultures of the corpus cavernosum penis for basic research and tissue engineering
    Adrian Pilatz
    Department of Urology and Pediatric Urology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Eur Urol 47:710-8; discussion 718-9. 2005
    ....
  48. ncbi request reprint Does the extraperitoneal laparoscopic approach improve the outcome of radical prostatectomy?
    Jens Uwe Stolzenburg
    University of Leipzig, Department of Urology, Liebigstrasse 20, 04103 Leipzig, Germany
    Curr Urol Rep 5:115-22. 2004
    ..This article reviews the literature on minimally invasive (laparoscopic and endoscopic-extraperitoneal) radical prostatectomy...
  49. pmc Detection of prostate cancer with complexed PSA and complexed/total PSA ratio - is there any advantage?
    F Strittmatter
    Department of Urology, Hospital of the University Munich Campus Grosshadern, Munich, Germany
    Eur J Med Res 16:445-50. 2011
    ..To evaluate the performance of total PSA (tPSA), the free/total PSA ratio (f/tPSA), complexed PSA (cPSA) and the complexed/total PSA ratio (c/tPSA) in prostate cancer detection...
  50. ncbi request reprint Ureteric reconstruction
    C G Stief
    Department of Urology, Medizinische Hochschule Hannover, Germany
    BJU Int 91:138-42. 2003
    ..In this review, the indications for reconstruction of a specific ureteric defect, the required techniques and postoperative recommendations are discussed...
  51. doi request reprint Catheter-based intraluminal optical coherence tomography versus endoluminal ultrasonography of porcine ureter ex vivo
    U L Mueller-Lisse
    Department of Urology, University of Munich, Munich, Germany
    Urology 73:1388-91. 2009
    ..Catheter-guided OCT is a new method of intraluminal microstructural imaging, with a spatial resolution of 10-20 mum...
  52. ncbi request reprint Effects of various nitric oxide donating agents on the contractility and cyclic nucleotide turnover of human seminal vesicles in vitro
    Olaf Heuer
    Department of Urology, Hannover Medical School, Hannover, Germany
    Urology 59:958-62. 2002
    ....
  53. ncbi request reprint Distribution and functional significance of phosphodiesterase isoenzymes in the human lower urinary tract
    Stefan Uckert
    Department of Urology, Hannover Medical School, 30625, Hannover, Germany
    World J Urol 23:368-73. 2005
    ..The purpose of this review is to summarize the current knowledge on the distribution and potential functional significance of PDE isoenzymes in the human lower urinary tract...
  54. doi request reprint Expression of cAMP-dependent protein kinase isoforms in the human prostate: functional significance and relation to PDE4
    Eginhard Waldkirch
    Hannover Medical School, Department of Urology and Uro Oncology, Hannover, Germany
    Urology 76:515.e8-14. 2010
    ..To investigate the expression of isoforms of the cyclic AMP (cAMP)-dependent protein kinase (cAK) in the transition zone of the human prostate and the functional significance of the enzyme in the control of prostate smooth muscle...
  55. doi request reprint Lymphovascular invasion is an independent predictor of oncological outcomes in patients with lymph node-negative urothelial bladder cancer treated by radical cystectomy: a multicentre validation trial
    Christian Bolenz
    Department of Urology, Mannheim Medical Centre, University of Heidelberg, Germany
    BJU Int 106:493-9. 2010
    ..To validate the association of lymphovascular invasion (LVI) with disease recurrence and cancer-specific survival (CSS) in a multicentre cohort of patients treated with radical cystectomy (RC) for urothelial bladder cancer (UBC)...
  56. ncbi request reprint Evolution of endoscopic extraperitoneal radical prostatectomy (EERPE)--technical improvements and development of a nerve-sparing, potency-preserving approach
    Jens Uwe Stolzenburg
    Department of Urology, University of Leipzig, Liebigstrasse 20, 04103 Leipzig, Germany
    World J Urol 21:147-52. 2003
    ....
  57. doi request reprint Intraoperative photodynamic evaluation of surgical margins during endoscopic extraperitoneal radical prostatectomy with the use of 5-aminolevulinic acid
    Roman Ganzer
    Department of Urology, University of Regensburg, Krankenhaus St Josef, Regensburg, Germany
    J Endourol 23:1387-94. 2009
    ..The intention of this study was to describe the specific technique of photodynamic diagnosis (PDD) in patients undergoing EERPE and report on the potential to detect PSM under PDD...
  58. ncbi request reprint Non-genomic effects of androgens on isolated human vascular and nonvascular penile erectile tissue
    Eginhard Waldkirch
    Hannover Medical School, Department of Urology, Hannover, Germany
    BJU Int 101:71-5; discussion 75. 2008
    ....
  59. doi request reprint Complications of the AdVance transobturator male sling in the treatment of male stress urinary incontinence
    Ricarda M Bauer
    Department of Urology, Ludwig Maximilian University, Munich, Germany
    Urology 75:1494-8. 2010
    ..To evaluate prospectively the complication rate of the retrourethral transobturator sling (AdVance sling) for the functional treatment of male stress urinary incontinence (SUI)...
  60. ncbi request reprint Lymphoscintigraphy in penile cancer: limited value of sentinel node biopsy in patients with clinically suspicious lymph nodes
    E Hungerhuber
    Department of Urology, Klinikum Grosshadern, Ludwig Maximilians University, Marchioninistr 15, 81377, Munich, Germany
    World J Urol 24:319-24. 2006
    ..However, dynamic sentinel node biospy is still a promising strategy to identify lymphatic spreading in clinically N0 patients and therefore to prevent unnecessary groin dissection...
  61. ncbi request reprint Carcinoma of the collecting ducts of Bellini of the kidney: adjuvant chemotherapy followed by multikinase-inhibition with sunitinib
    Michael Staehler
    Department of Urology, University of Munich, Klinikum Grosshadern, Marchioninistr 15, 81377 Munchen, Germany
    Eur J Med Res 13:531-5. 2008
    ..Carcinoma of the collecting ducts of Bellini of the kidney (CDC) is very rare but among the most aggressive urological entities. Standard therapy is not well defined with questionable efficacy...
  62. pmc Perioperative search for circulating tumor cells in patients undergoing radical cystectomy for bladder cancer
    A Karl
    Department of Urology, Ludwig Maximilians University, LMU Munich, Marchionistr 15, 81377 Munich, Germany
    Eur J Med Res 14:487-90. 2009
    ..The presence of CTCs in whole blood before and during radical cystectomy could provide further information on disease status, and could be used as an indicator to determine the need for adjuvant or even perioperative chemotherapy...
  63. ncbi request reprint Adverse effects of drug therapies on male and female sexual function
    Th Stadler
    Department of Urology, Faculty of Medicine, University Hospital Grosshadern, Ludwig Maximilians University, Marchioninistr 15, 81377 Munich, Germany
    World J Urol 24:623-9. 2006
    ....
  64. ncbi request reprint Immunohistochemical distribution of cAMP- and cGMP-phosphodiesterase (PDE) isoenzymes in the human prostate
    Stefan Uckert
    Hannover Medical School, Department of Urology, Hannover, Germany
    Eur Urol 49:740-5. 2006
    ..The aim of the present study was to evaluate by means of immunohistochemistry the expression and distribution of some cAMP- and cGMP-PDE isoenzymes in the prostate...
  65. ncbi request reprint Phosphodiesterase inhibitors for the treatment of erectile dysfunction
    Andrea Kuthe
    Department of Urology, Medizinische Hochschule, Hannover, Germany
    Curr Opin Investig Drugs 3:1489-95. 2002
    ....
  66. doi request reprint pT3 Substaging is a prognostic indicator for lymph node negative urothelial carcinoma of the bladder
    Derya Tilki
    Department of Urology, Ludwig Maximilians University, Klinikum Grosshadern, Munich, Germany
    J Urol 184:470-4. 2010
    ..We assessed the prognostic value of pT3 bladder urothelial carcinoma substaging...
  67. ncbi request reprint In vitro effects of a novel class of nitric oxide (NO) donating compounds on isolated human erectile tissue
    Michael Seidler
    Depatment of Urology, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Eur Urol 42:523-8. 2002
    ..Effects were compared to those of sodium nitroprusside (SNP) and sildenafil citrate...
  68. ncbi request reprint Complications and early postoperative outcome after open prostatectomy in patients with benign prostatic enlargement: results of a prospective multicenter study
    Christian Gratzke
    Department of Urology, Ludwig Maximilians University, Faculty of Medicine, University Hospital Grosshadern, Munich, Germany
    J Urol 177:1419-22. 2007
    ....
  69. ncbi request reprint Effects of various nitric oxide-donating drugs on adrenergic tension of human seminal vesicles in vitro
    Stefan Machtens
    Department of Urology, Hannover Medical School, Hannover, Germany
    Urology 61:479-83. 2003
    ..However, information on the significance of NO-mediated signal transduction in the functional control of the mammalian seminal vesicles is still sparse...
  70. doi request reprint Radical cystectomy in the elderly patient: a contemporary comparison of perioperative complications in a single institution series
    Derya Tilki
    Department of Urology, Ludwig Maximilians University Munich, Campus Grosshadern, Marchioninistr 15, 81377, Munich, Germany
    World J Urol 28:445-50. 2010
    ..To report on our recent experience with peri- and postoperative morbidity of radical cystectomy in patients 75 years and older compared to younger patients...
  71. doi request reprint Photodynamic diagnosis of prostate cancer using 5-aminolevulinic acid--first clinical experiences
    Dirk Zaak
    Department of Urology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Urology 72:345-8. 2008
    ..To study the feasibility of 5-aminolevulinic-acid (5-ALA)-induced photodynamic diagnosis (PDD) for the evaluation of the surgical margins (SMs) during radical prostatectomy (RP) in patients with prostate cancer (PCa)...
  72. doi request reprint Ho:YAG-laser: treatment of vesicourethral strictures after radical prostatectomy
    Markus J Bader
    Department of Urology, University Hospital Grosshadern, Ludwig Maximilians University Munich, 81377 Munich, Germany
    World J Urol 28:169-72. 2010
    ..To review the indication, feasibility and treatment outcome of Ho:YAG laser application for definitive endoscopic treatment of anastomotic stricture formation after radical prostatectomy...
  73. doi request reprint Anatomy, physiology, and pathophysiology of erectile dysfunction
    Christian Gratzke
    Department of Urology, Ludwig Maximilians Universitat, Munchen, Germany
    J Sex Med 7:445-75. 2010
    ..A critical evaluation of the current state of knowledge is essential to provide perspective for future research and development of new therapies...
  74. doi request reprint The impact of lymphadenectomy and lymph node metastasis on the outcomes of radical cystectomy for bladder cancer
    Alexander Karl
    Department of Urology, University of Munich, LMU, Campus Grosshadern, Munich, Germany
    Eur Urol 55:826-35. 2009
    ..The presence of lymph node metastases and the extent of lymphadenectomy have both been shown to influence the outcome of patients with muscle-invasive bladder cancer...
  75. ncbi request reprint Serum levels of human growth hormone during different penile conditions in the cavernous and systemic blood of healthy men and patients with erectile dysfunction
    Armin J Becker
    Department of Urology, Hannover Medical School, Hannover, Germany
    Urology 59:609-14. 2002
    ..It has recently been demonstrated that GH serum levels in the systemic and cavernous blood of healthy men increases during developing penile erection...
  76. doi request reprint Quality of life and perioperative outcomes after retroperitoneoscopic radical nephrectomy (RN), open RN and nephron-sparing surgery in patients with renal cell carcinoma
    Christian Gratzke
    Department of Urology, Ludwig Maximilians University Munich, Germany
    BJU Int 104:470-5. 2009
    ....
  77. ncbi request reprint Molecular imaging of tumor blood vessels in prostate cancer
    Derya Tilki
    Department of Urology, University Hospital Grosshadern Munich, Marchioninistr 15, D 81377 Munchen, Germany
    Anticancer Res 29:1823-9. 2009
    ..Molecular contrast agents targeting the vasculature will allow clinicians the visualization of vascular remodelling processes taking place under anti-angiogenic therapy and improve tumor diagnosis and follow-up...
  78. ncbi request reprint In vitro effects of PDE5 inhibitors sildenafil, vardenafil and tadalafil on isolated human ureteral smooth muscle: a basic research approach
    Christian Gratzke
    Department of Urology, Ludwig Maximilians University, University Hospital Grosshadern, Marchioninistr 15, 81377, Munich, Germany
    Urol Res 35:49-54. 2007
    ..Nevertheless, further studies are indicated in order to evaluate as to whether there might be a use for PDE5 inhibitors in the treatment of ureteral stone disease...
  79. doi request reprint Potential mechanism of action of human growth hormone on isolated human penile erectile tissue
    Stefan Uckert
    Department of Urology and Uro Oncology, Hannover Medical School, Hannover, Germany
    Urology 75:968-73. 2010
    ..Nevertheless, it still remains unclear which intracellular pathways mediate the physiological effects of GH on the human corpus cavernosum (HCC)...
  80. doi request reprint Stage pT0 at radical cystectomy confers improved survival: an international study of 4,430 patients
    Derya Tilki
    Department of Urology, Ludwig Maximilians University Munich, Klinikum Grosshadern, Munich, Germany
    J Urol 184:888-94. 2010
    ..We also compared outcomes in patients with pT0 bladder urothelial carcinoma to those in patients with other stages and assessed the effect of clinical stage on outcome...
  81. ncbi request reprint Cavernous and systemic plasma levels of norepinephrine and epinephrine during different penile conditions in healthy men and patients with erectile dysfunction
    Armin J Becker
    Department of Urology, Hannover Medical School, Hannover, Germany
    Urology 59:281-6. 2002
    ..Knowledge concerning the neurophysiology of penile erection has improved tremendously during the past two decades. However, only few in vivo studies on human peripheral neurotransmission have been carried out to date...
  82. doi request reprint The growth rate of large renal masses opposes active surveillance
    Michael Staehler
    Department of Urology, University of Munich, Klinikum Grosshadern, Germany
    BJU Int 105:928-31. 2010
    ..1-0.7 cm/year, but little is known about the progression of large masses...
  83. doi request reprint Activated RhoA/Rho kinase impairs erectile function after cavernous nerve injury in rats
    Christian Gratzke
    Department of Urology, Ludwig Maximilians University Munich, Munich, Germany
    J Urol 184:2197-204. 2010
    ..We hypothesized that erectile dysfunction after bilateral cavernous nerve injury is accompanied by up-regulation of RhoA/rho kinase activity in the rat penis...
  84. doi request reprint Phase 1 trial of allogeneic gene-modified tumor cell vaccine RCC-26/CD80/IL-2 in patients with metastatic renal cell carcinoma
    Alexander Buchner
    Department of Urology, Ludwig Maximilian University of Munich, 81377 Munich, Germany
    Hum Gene Ther 21:285-97. 2010
    ..These results suggest that this vaccine could be useful in combination therapies and/or minimal residual disease...
  85. doi request reprint Does the current World Health Organization classification predict the outcome better in patients with noninvasive bladder cancer of early or regular onset?
    Maximilian Burger
    Department of Urology, Friedrich Alexander University, Erlangen, Germany
    BJU Int 102:194-7. 2008
    ....
  86. ncbi request reprint Preliminary results on the off-label use of duloxetine for the treatment of stress incontinence after radical prostatectomy or cystectomy
    Boris Schlenker
    Department of Urology, Ludwig Maximilian University of Munich, Germany
    Eur Urol 49:1075-8. 2006
    ..The aim of our study was to evaluate if duloxetine is safe and effective for men with stress incontinence after radical prostatectomy or cystectomy...
  87. ncbi request reprint Cytotoxicity of different intracavernous vasoactive drugs on cultured endothelial cells of human corpus cavernosum penis
    Dirk Schultheiss
    Department of Urology and Pediatric Urology, Hannover Medical School, Germany
    Urology 64:598-602. 2004
    ..The endothelial layer of the corpus cavernosum plays an important role in signal transduction of penile erection and is directly exposed to vasoactive agents after intracavernous injection for erectile dysfunction...
  88. ncbi request reprint Detection of low-molecular-mass plasma peptides in the cavernous and systemic blood of healthy men during penile flaccidity and rigidity--an experimental approach using the novel differential peptide display technology
    Harald Tammen
    BioVisioN AG, Hannover, Germany
    Urology 59:784-9. 2002
    ..Nevertheless, it is not yet known which particular peptides are essential in the regulation of penile flaccidity, tumescence, rigidity, and detumescence...
  89. ncbi request reprint Systemic and cavernous plasma levels of vasoactive intestinal polypeptide during sexual arousal in healthy males
    Armin J Becker
    Hannover Medical School, Department of Urology, Germany
    World J Urol 20:59-63. 2002
    ..Nevertheless, our data indicate that the peptide is not the main non-adrenergic, non-cholinergic mediator of penile tumescence and rigidity in human males...
  90. ncbi request reprint Is there an inhibitory role of cortisol in the mechanism of male sexual arousal and penile erection?
    Stefan Uckert
    Department of Urology, Hannover Medical School, 30625 Hannover, Germany
    Urol Res 31:402-6. 2003
    ....
  91. ncbi request reprint Catheter-based intraluminal optical coherence tomography (OCT) of the ureter: ex-vivo correlation with histology in porcine specimens
    Ulrike L Mueller-Lisse
    Department of Urology, University of Munich, Nussbaumstrasse 20, 80336, Munich, Germany
    Eur Radiol 16:2259-64. 2006
    ..Intraluminal OCT provides histology-like images of the ureter in porcine specimens ex vivo and reliably distinguishes between urothelium and deeper tissue layers of the ureteral wall...
  92. ncbi request reprint Update on phosphodiesterase (PDE) isoenzymes as pharmacologic targets in urology: present and future
    Stefan Uckert
    Hannover Medical School, Department of Urology, Hannover 30625, Germany
    Eur Urol 50:1194-207; discussion 1207. 2006
    ..This review attempts to describe the physiology and pharmacology of phosphodiesterase (PDE) isoenzymes with special regard to their (potential) use in disorders of the human urogenital tract...
  93. ncbi request reprint Risk stratification in penile carcinoma: 25-year experience with surgical inguinal lymph node staging
    Edwin Hungerhuber
    Department of Urology, Klinikum Grosshadern, University of Munich, Munich, Germany
    Urology 68:621-5. 2006
    ..We report our experience with surgical lymph node staging and evaluate which group of patients could be assigned to a wait-and-see strategy or dynamic sentinel node biopsy and which group should undergo groin dissection...
  94. ncbi request reprint Possible role of bioactive peptides in the regulation of human detrusor smooth muscle - functional effects in vitro and immunohistochemical presence
    Stefan Uckert
    Hanover Medical School, Department of Urology, Carl Neuberg Str 1, 30625 Hanover, Germany
    World J Urol 20:244-9. 2002
    ....
  95. doi request reprint Effects of phosphodiesterase inhibitors on tension induced by norepinephrine and accumulation of cyclic nucleotides in isolated human prostatic tissue
    Stefan Uckert
    Department of Urology, Hannover Medical School, Hannover, Germany
    Urology 71:526-30. 2008
    ....
  96. ncbi request reprint Expression of guanylyl cyclase B in the human corpus cavernosum penis and the possible involvement of its ligand C-type natriuretic polypeptide in the induction of penile erection
    Andrea Kuthe
    Department of Urology, Hannover Medical School and IPF PharmaCeuticals, Hannover, Germany
    J Urol 169:1918-22. 2003
    ..Therefore, we investigated the suitability of membrane bound guanylyl cyclases as alternative target proteins...
  97. ncbi request reprint Squamous cell carcinoma antigen correlates with tumor burden but lacks prognostic potential for occult lymph node metastases in penile cancer
    Edwin Hungerhuber
    Department of Urology, Klinikum Grosshadern, University of Munich, Munich, Germany
    Urology 70:975-9. 2007
    ..Squamous cell carcinoma (SCC) antigen is a well-known marker for various carcinomas. Our aim was to evaluate the value of the SCC antigen in terms of lymph node staging and treatment control...
  98. ncbi request reprint Systemic and cavernous plasma levels of vasopressin in healthy males during different functional conditions of the penis
    Armin J Becker
    Hannover Medical School, Department of Urology, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Urol Res 31:66-9. 2003
    ..Nevertheless, our data indicate that the decrease in systemic AVP levels in response to sexual arousal might be a prerequisite to facilitate penile tumescence and rigidity in healthy males...
  99. ncbi request reprint Oxytocin plasma levels in the systemic and cavernous blood of healthy males during different penile conditions
    Stefan Uckert
    Department of Urology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    World J Urol 20:323-6. 2003
    ..Our results support the hypothesis of a pivotal role of OT in the mechanism of male sexual arousal and penile erection and provide a rationale for the use of apomorphine in the treatment of erectile dysfunction...
  100. ncbi request reprint In vitro viability of human cavernosal endothelial and fibroblastic cells after exposure to papaverine/phentolamine and prostaglandin E1
    Adrian Pilatz
    Department of Urology and Paediatric Urology, Hannover Medical School, Hannover, Germany
    BJU Int 95:1351-7. 2005
    ....
  101. ncbi request reprint Expression of cAMP and cGMP-phosphodiesterase isoenzymes 3, 4, and 5 in the human clitoris: immunohistochemical and molecular biology study
    Matthias Oelke
    Department of Urology, University of Amsterdam, Academic Medical Center, Amsterdam, The Netherlands
    Urology 67:1111-6. 2006
    ..We sought to elucidate the presence of the phosphodiesterase (PDE) isoenzymes 3, 4, and 5 in the human clitoris using immunohistochemical and molecular biology methods...