Thomas F Schulz

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. pmc Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein
    Melanie M Brinkmann
    Institut fur Virologie, Medizinische Hochschule Hannover, D 30625 Hannover, Germany
    J Virol 77:9346-58. 2003
  2. ncbi request reprint Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8): key aspects of epidemiology and pathogenesis
    Abel Viejo-Borbolla
    Department of Virology, Hannover Medical School, Hannover, Germany
    AIDS Rev 5:222-9. 2003
  3. pmc Kaposi's sarcoma herpesvirus K15 protein contributes to virus-induced angiogenesis by recruiting PLCγ1 and activating NFAT1-dependent RCAN1 expression
    Kiran Bala
    Institute of Virology, Hannover Medical School, Hannover, Germany
    PLoS Pathog 8:e1002927. 2012
  4. pmc A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins
    Jan Hellert
    Department of Structural Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    PLoS Pathog 9:e1003640. 2013
  5. pmc HHV-8 encoded LANA-1 alters the higher organization of the cell nucleus
    Gyorgy Stuber
    Department of Microbiology, Tumor and Cell Biology MTC and Center for Integrative Recognition in the Immune System, Karolinska Institute, Stockholm, Sweden
    Mol Cancer 6:28. 2007
  6. pmc HLA polymorphisms and detection of kaposi sarcoma-associated herpesvirus DNA in saliva and peripheral blood among children and their mothers in the uganda sickle cell anemia KSHV Study
    Mercy Guech-Ongey
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics DCEG, National Cancer Institute, Bethesda, Maryland, USA
    Infect Agent Cancer 5:21. 2010
  7. pmc Clinical relevance of and risk factors for HSV-related tracheobronchitis or pneumonia: results of an outbreak investigation
    Ilka Engelmann
    Institute of Virology, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Crit Care 11:R119. 2007
  8. ncbi request reprint The pleiotropic effects of Kaposi's sarcoma herpesvirus
    Thomas F Schulz
    Department of Virology, Hannover Medical School, Germany
    J Pathol 208:187-98. 2006
  9. doi request reprint Cancer and viral infections in immunocompromised individuals
    Thomas F Schulz
    Institute of Virology, Hannover Medical School, Hannover 60325, Germany
    Int J Cancer 125:1755-63. 2009
  10. pmc The ubiquitin-specific protease USP7 modulates the replication of Kaposi's sarcoma-associated herpesvirus latent episomal DNA
    Wiebke Jäger
    Institut fur Virologie, Medizinische Hochschule Hannover, Hannover, Germany
    J Virol 86:6745-57. 2012

Collaborators

Detail Information

Publications54

  1. pmc Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein
    Melanie M Brinkmann
    Institut fur Virologie, Medizinische Hochschule Hannover, D 30625 Hannover, Germany
    J Virol 77:9346-58. 2003
    ..These findings illustrate that the 45-kDa K15 protein engages pathways similar to LMP1, LMP2A, STP, Tip, and Tio but combines functional features that are separated between LMP1 and LMP2A or STP and Tip...
  2. ncbi request reprint Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8): key aspects of epidemiology and pathogenesis
    Abel Viejo-Borbolla
    Department of Virology, Hannover Medical School, Hannover, Germany
    AIDS Rev 5:222-9. 2003
    ..This review addresses key aspects of KSHV epidemiology, life cycle and pathogenesis, including the role played by key latent and lytic KSHV genes...
  3. pmc Kaposi's sarcoma herpesvirus K15 protein contributes to virus-induced angiogenesis by recruiting PLCγ1 and activating NFAT1-dependent RCAN1 expression
    Kiran Bala
    Institute of Virology, Hannover Medical School, Hannover, Germany
    PLoS Pathog 8:e1002927. 2012
    ..This effect is abrogated when K15 is deleted (KSHVΔK15) or silenced by an siRNA targeting the K15 expression. Our study establishes K15 as one of the KSHV proteins that contribute to KSHV-induced angiogenesis...
  4. pmc A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins
    Jan Hellert
    Department of Structural Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    PLoS Pathog 9:e1003640. 2013
    ..In summary, our data provide a structural basis for the formation of higher order LANA oligomers, which is required for nuclear speckle formation, latent replication and viral persistence. ..
  5. pmc HHV-8 encoded LANA-1 alters the higher organization of the cell nucleus
    Gyorgy Stuber
    Department of Microbiology, Tumor and Cell Biology MTC and Center for Integrative Recognition in the Immune System, Karolinska Institute, Stockholm, Sweden
    Mol Cancer 6:28. 2007
    ..The induction of histone modification in adjacent host genes may lead to altered gene expression, thereby contributing to the viral oncogenesis...
  6. pmc HLA polymorphisms and detection of kaposi sarcoma-associated herpesvirus DNA in saliva and peripheral blood among children and their mothers in the uganda sickle cell anemia KSHV Study
    Mercy Guech-Ongey
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics DCEG, National Cancer Institute, Bethesda, Maryland, USA
    Infect Agent Cancer 5:21. 2010
    ..Larger population-based studies are needed to estimate the magnitude and direction of association of HLA with KSHV shedding and viral control...
  7. pmc Clinical relevance of and risk factors for HSV-related tracheobronchitis or pneumonia: results of an outbreak investigation
    Ilka Engelmann
    Institute of Virology, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Crit Care 11:R119. 2007
    ....
  8. ncbi request reprint The pleiotropic effects of Kaposi's sarcoma herpesvirus
    Thomas F Schulz
    Department of Virology, Hannover Medical School, Germany
    J Pathol 208:187-98. 2006
    ..Viral proteins expressed during both the latent and the lytic phase of the viral life cycle contribute to the pathogenesis of KSHV-associated diseases...
  9. doi request reprint Cancer and viral infections in immunocompromised individuals
    Thomas F Schulz
    Institute of Virology, Hannover Medical School, Hannover 60325, Germany
    Int J Cancer 125:1755-63. 2009
    ....
  10. pmc The ubiquitin-specific protease USP7 modulates the replication of Kaposi's sarcoma-associated herpesvirus latent episomal DNA
    Wiebke Jäger
    Institut fur Virologie, Medizinische Hochschule Hannover, Hannover, Germany
    J Virol 86:6745-57. 2012
    ..N. Holowaty et al., J. Biol. Chem. 278:29987-29994, 2003), may thereby be a conserved feature among gammaherpesvirus latent origin binding proteins...
  11. doi request reprint Identification and functional characterization of a spliced rhesus rhadinovirus gene with homology to the K15 gene of Kaposi's sarcoma-associated herpesvirus
    Linding Wang
    Institute of Virology, Hannover Medical School, D 30625 Hannover, Germany
    J Gen Virol 90:1190-201. 2009
    ..These data suggest functional differences between terminal membrane proteins at the right end of the genomes of Old World primate gamma-2 herpesviruses...
  12. pmc The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells
    Darya A Haas
    Institute of Virology, Hannover Medical School, Hannover, Germany
    PLoS Pathog 9:e1003737. 2013
    ....
  13. pmc Activation of the B cell antigen receptor triggers reactivation of latent Kaposi's sarcoma-associated herpesvirus in B cells
    Semra Kati
    Institute of Virology, Hanover Medical School, Hanover, Germany
    J Virol 87:8004-16. 2013
    ....
  14. pmc Brd2/RING3 interacts with a chromatin-binding domain in the Kaposi's Sarcoma-associated herpesvirus latency-associated nuclear antigen 1 (LANA-1) that is required for multiple functions of LANA-1
    Abel Viejo-Borbolla
    Department of Virology, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    J Virol 79:13618-29. 2005
    ....
  15. doi request reprint Community-acquired respiratory viral infections in lung transplant recipients: a single season cohort study
    Jens Gottlieb
    Department of Pulmonary Medicine, Hannover Medical School, Hannover, Germany
    Transplantation 87:1530-7. 2009
    ..The impact of community-acquired respiratory virus (CARV) infections on bronchiolitis obliterans syndrome (BOS) and outcome after lung transplantation (LTx) and diagnostic techniques were prospectively evaluated...
  16. ncbi request reprint WHAT do viruses BET on?
    Magdalena Weidner-Glunde
    Hannover Medical School, Institute of Virology, Hannover, Germany
    Front Biosci (Landmark Ed) 15:537-49. 2010
    ..Additionally some retroviruses seem to encode proteins that mimic Brd4 functions and hijack Brd4-associated protein complexes to use them for their own transcription...
  17. pmc The interaction of the gammaherpesvirus 68 orf73 protein with cellular BET proteins affects the activation of cell cycle promoters
    Matthias Ottinger
    Institut fur Virologie, Medizinische Hochschule Hannover, Hannover, Germany
    J Virol 83:4423-34. 2009
    ..These findings point to parallels between the transcriptional activator functions of rhadinoviral orf73 proteins and papillomavirus E2 proteins...
  18. pmc Bromo- and extraterminal domain chromatin regulators serve as cofactors for murine leukemia virus integration
    Saumya Shree Gupta
    Institute of Virology, Hannover Medical School, Hannover, Germany
    J Virol 87:12721-36. 2013
    ..Our data suggest that BET proteins might act as chromatin-bound acceptors for the MLV preintegration complex. These results could pave a way to redirecting MLV DNA integration as a basis for creating safer retroviral vectors. ..
  19. ncbi request reprint Functional characterization of the M-type K15-encoded membrane protein of Kaposi's sarcoma-associated herpesvirus
    Linding Wang
    Department of Virology, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    J Gen Virol 88:1698-707. 2007
    ..Therefore, K15-M and K15-P can trigger similar intracellular signalling pathways, despite their extensive sequence divergence...
  20. pmc Deletion of Kaposi's sarcoma-associated herpesvirus FLICE inhibitory protein, vFLIP, from the viral genome compromises the activation of STAT1-responsive cellular genes and spindle cell formation in endothelial cells
    Khaled R Alkharsah
    Institut fur Virologie, Hannover Medical School, Hannover, Germany
    J Virol 85:10375-88. 2011
    ..These findings document the impact of KSHV vFLIP on the transcriptome of primary endothelial cells during viral persistence and highlight the role of vFLIP in the activation of STAT1/STAT2 and STAT-responsive cellular genes by KSHV...
  21. doi request reprint Viremia after lung transplant: a cohort study on risk factors and symptoms associated with detection of Epstein-Barr virus
    Frauke Mattner
    Hannover Medical School, Hannover, Germany
    Prog Transplant 22:155-60. 2012
    ..Detection of viral DNA after transplant was frequent and clinically relevant...
  22. pmc Role of the Kaposi's sarcoma-associated herpesvirus K15 SH3 binding site in inflammatory signaling and B-cell activation
    Marcel Pietrek
    Institute of Virology, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hanover, Germany
    J Virol 84:8231-40. 2010
    ..However, the PPLP motif is essential for the decrease in B-cell receptor-mediated signaling induced by K15, as measured by calcium mobilization assays...
  23. doi request reprint Detection of Epstein-Barr virus DNA in peripheral blood is associated with the development of bronchiolitis obliterans syndrome after lung transplantation
    Ilka Engelmann
    Institute of Virology, Medizinische Hochschule Hannover, Hannover, Germany
    J Clin Virol 45:47-53. 2009
    ..The long-term success of lung transplantation is limited by the development of bronchiolitis obliterans syndrome (BOS). Virus infections may be involved in the development of BOS...
  24. doi request reprint No human virus sequences detected by next-generation sequencing in benign verrucous skin tumors occurring in BRAF-inhibitor-treated patients
    Tina Ganzenmueller
    Institute of Virology, Hannover Medical School, Hannover, Germany
    Exp Dermatol 22:725-9. 2013
    ....
  25. ncbi request reprint Influence of HLA alleles on shedding of Kaposi sarcoma-associated herpesvirus in saliva in an African population
    Khaled R Alkharsah
    Institute of Virology, Hannover Medical School, Hannover, 30625, Germany
    J Infect Dis 195:809-16. 2007
    ....
  26. pmc The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cells
    Ildar Gabaev
    Institute of Virology, Hannover Medical School, Hannover, Germany
    PLoS Pathog 7:e1002432. 2011
    ..We therefore conclude that pUL11 has immunosuppressive properties, and that disruption of T cell function via inhibition of CD45 is a previously unknown immunomodulatory strategy of CMV...
  27. ncbi request reprint Absence of Kaposi's sarcoma-associated herpesvirus in patients with pulmonary arterial hypertension
    Cornelia Henke-Gendo
    Institute of Virology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Am J Respir Crit Care Med 172:1581-5. 2005
    ..Recently, evidence of KSHV infection was reported in plexiform lesions of idiopathic pulmonary arterial hypertension (IPAH) as well as in adjacent parenchyma and bronchial epithelial cells...
  28. ncbi request reprint Human herpesvirus 8: biology and role in the pathogenesis of Kaposi's sarcoma and other AIDS-related malignancies
    Abel Viejo-Borbolla
    Department of Virology, Hannover Medical School, Carl Neuberg Strasse1, D 30625 Hannover, Germany
    Curr HIV/AIDS Rep 1:5-11. 2004
    ..This review offers an update on the epidemiology and the role of KSHV genes in the development of disease...
  29. ncbi request reprint Delayed seroconversion and rapid onset of lymphoproliferative disease after transmission of human T-cell lymphotropic virus type 1 from a multiorgan donor
    Ilona Glowacka
    Institute of Virology, Hannover Medical School
    Clin Infect Dis 57:1417-24. 2013
    ..An HTLV-1 transmission event caused by a multiple organ donor was investigated. Validity of diagnostic procedures and HTLV-1 disease association in immunosuppressed organ recipients were analyzed...
  30. doi request reprint Next-generation sequencing fails to identify human virus sequences in cutaneous squamous cell carcinoma
    Tina Ganzenmueller
    Institute of Virology, Hannover Medical School, Hannover, Germany
    Int J Cancer 131:E1173-9. 2012
    ..Further studies are required to exclude the presence of viruses in NMSC, which cannot easily be identified on the basis of sequence homology to known viruses...
  31. pmc Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome contains a duplication of a long unique-region fragment within the terminal repeat region
    Yuri Yakushko
    Institute of Virology, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    J Virol 85:4612-7. 2011
    ..This observation needs to be kept in mind if viral genes located within the duplicated region are to be mutated in KSHV-BAC36...
  32. pmc A role for the internal repeat of the Kaposi's sarcoma-associated herpesvirus latent nuclear antigen in the persistence of an episomal viral genome
    Khaled R Alkharsah
    Institute of Virology, Hannover Medical School, Hannover, Germany
    J Virol 86:1883-7. 2012
    ..These findings suggest a role for the LANA IR in KSHV episomal maintenance without its being required for replication...
  33. doi request reprint Symptomatic hepatitis B virus (HBV) reactivation despite reduced viral fitness is associated with HBV test and immune escape mutations in an HIV-coinfected patient
    Cornelia Henke-Gendo
    Institute of Virology, Medical School Hannover, Carl Neuberg Strasse 1, Hannover, Germany
    J Infect Dis 198:1620-4. 2008
    ..Immune escape mutants evolved even without exogenous selective pressure, hampered detection in HBsAg screening, and might be transmitted during reactivation with high HBV loads...
  34. ncbi request reprint Risk of rabies infection and adverse effects of postexposure prophylaxis in healthcare workers and other patient contacts exposed to a rabies virus-infected lung transplant recipient
    Frauke Mattner
    Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany
    Infect Control Hosp Epidemiol 28:513-8. 2007
    ..The patient was given ventilatory assistance and cared for postoperatively for 6 weeks before a diagnosis of rabies virus infection was made. Postexposure prophylaxis (PEP) was offered to potentially exposed healthcare workers (HCWs)...
  35. ncbi request reprint Transmission and disease association of Kaposi's sarcoma-associated herpesvirus: recent developments
    Cornelia Henke-Gendo
    Department of Virology, Hannover Medical School, Hannover, Germany
    Curr Opin Infect Dis 17:53-7. 2004
    ..Nevertheless recent developments on other modes of transmission of the virus have been made during the last years and are summarized in this review. Furthermore, recent published disease associations are discussed...
  36. pmc A Domain in the C-terminal region of latency-associated nuclear antigen 1 of Kaposi's sarcoma-associated Herpesvirus affects transcriptional activation and binding to nuclear heterochromatin
    Abel Viejo-Borbolla
    Department of Virology, Hannover Medical School, Hannover, Germany
    J Virol 77:7093-100. 2003
    ....
  37. ncbi request reprint Kaposi's sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8)
    Thomas F Schulz
    Department of Virology, Hannover Medical School, Germany
    Virus Res 82:115-26. 2002
  38. pmc Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus
    Melanie M Brinkmann
    Institut fur Virologie, Medizinische Hochschule Hannover, Carl Neuberg Str 1, D 30625 Hannover, Germany
    J Virol 81:42-58. 2007
    ..Our study establishes K15 as one of the KSHV lytic genes that are inducing expression of multiple cytokines, which have been shown to play an important role in KSHV-associated pathogenesis...
  39. ncbi request reprint Regulation of intracellular signalling by the terminal membrane proteins of members of the Gammaherpesvirinae
    Melanie M Brinkmann
    Institut fur Virologie, Medizinische Hochschule Hannover, Germany
    J Gen Virol 87:1047-74. 2006
    ..Whether R1 and K1 contribute to the oncogenic properties of KSHV and RRV has not been established satisfactorily, despite their transforming qualities in experimental settings...
  40. ncbi request reprint Risk factors for human herpesvirus 8 infection in a cohort of drug users in the Netherlands, 1985-1996
    Neil Renwick
    Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, The Netherlands
    J Infect Dis 185:1808-12. 2002
    ..Unlike HIV-1, HBV, or HCV infection, HHV-8 infection is uncommon in Amsterdam drug users, as is HHV-8 transmission through IDU...
  41. ncbi request reprint Mother-to-child transmission of human herpesvirus-8 in South Africa
    Martin Dedicoat
    Liverpool School of Tropical Medicine, Liverpool, and Cancer Research UK Epidemiology Unit, Oxford, United Kingdom
    J Infect Dis 190:1068-75. 2004
    ..1-6.2). The presence of HHV-8 DNA in maternal saliva was unrelated to latent antibodies in children. Saliva could be a route of transmission of HHV-8 from person to person, although other routes cannot be ruled out...
  42. ncbi request reprint Latent nuclear antigen of Kaposi's sarcoma herpesvirus/human herpesvirus-8 induces and relocates RING3 to nuclear heterochromatin regions
    Karin Mattsson
    Microbiology and Tumor Biology Center, Karolinska Institute, PO Box 280, S 171 77, Stockholm, Sweden
    J Gen Virol 83:179-88. 2002
    ..We suggest that LANA and RING3 may create a local euchromatic microenvironment around the viral episomes that are anchored to the heterochromatin...
  43. ncbi request reprint KSHV/HHV-8 infection of tubular epithelial cells in transplantation kidney
    Patrizia Barozzi
    Transplantation 82:851-2. 2006
  44. pmc Kaposi's sarcoma-associated herpesvirus LANA-1 interacts with the short variant of BRD4 and releases cells from a BRD4- and BRD2/RING3-induced G1 cell cycle arrest
    Matthias Ottinger
    Institut fur Virologie, Medizinische Hochschule Hannover, Carl Neuberg Str 1, 30625 Hannover, Germany
    J Virol 80:10772-86. 2006
    ..J. Barbera, J. V. Chodaparambil, B. Kelley-Clarke, V. Joukov, J. C. Walter, K. Luger, and K. M. Kaye, Science 311:856-861, 2006) of the LANA-1 N terminus with histones H2A and H2B...
  45. ncbi request reprint Increased seroprevalence of human herpes virus-8 in renal transplant recipients in Saudi Arabia
    Alhussein J Alzahrani
    Department of Microbiology, King Faisal University, Dammam, Saudi Arabia
    Nephrol Dial Transplant 20:2532-6. 2005
    ..Previous studies suggested a high rate of Kaposi's sarcoma in renal transplant patients in Saudi Arabia. The aim of this study was to investigate the prevalence of HHV-8 in Saudi renal transplant recipients and healthy controls...
  46. ncbi request reprint Risk factors for human Herpesvirus 8 infection and AIDS-associated Kaposi's sarcoma among men who have sex with men in a European multicentre study
    Elisa Martro
    Centre d Estudis Epidemiològics sobre l HIV SIDA de Catalunya, Departament de Salut, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
    Int J Cancer 120:1129-35. 2007
    ....
  47. pmc Use of a BJAB-derived cell line for isolation of human herpesvirus 8
    Paola Gasperini
    Department of Oncology and Surgical Sciences, Oncology Section, Via Gattamelata 64, Padua, I 35128 Italy
    J Clin Microbiol 43:2866-75. 2005
    ..BBF cells can be used to propagate HHV-8 from different biological samples as well as to clarify important issues related to virus-cell interactions in a context distinct from endothelial and PEL-derived cell lines...
  48. ncbi request reprint Vascular endothelial growth factor levels in serum do not increase following HIV type 1 and HHV8 seroconversion and lack correlation with AIDS-related Kaposi's sarcoma
    Neil Renwick
    Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    AIDS Res Hum Retroviruses 18:695-8. 2002
    ..Sequential measurement of VEGF in serum is not expected to contribute to the prediction or therapeutic monitoring of AIDS-KS...
  49. ncbi request reprint HHV-8 in pulmonary hypertension
    Cornelia Henke-Gendo
    N Engl J Med 350:194-5; author reply 194-5. 2004
  50. pmc Genotypic analysis of two hypervariable human cytomegalovirus genes
    Amanda J Bradley
    MRC Virology Unit, Institute of Virology, University of Glasgow, Glasgow, United Kingdom
    J Med Virol 80:1615-23. 2008
    ..The emerging scenario is that the HCMV genotypes developed in early human populations (or even earlier), becoming established via founder or bottleneck effects, and have spread, recombined and mixed worldwide in more recent times...
  51. ncbi request reprint Post-transplant Kaposi sarcoma originates from the seeding of donor-derived progenitors
    Patrizia Barozzi
    Department of Oncology and Hematology, University of Modena and Reggio Emilia, Modena, Italy
    Nat Med 9:554-61. 2003
    ..These data suggest the use of donor-derived HHV-8-specific T cells for the control of post-transplant KS...
  52. doi request reprint Changes in the immune responses against human herpesvirus-8 in the disease course of posttransplant Kaposi sarcoma
    Patrizia Barozzi
    Department of Oncology and Hematology, University of Modena and Reggio Emilia, Azienda Ospedaliera Policlinico, Via del Pozzo 71, Modena, Italy
    Transplantation 86:738-44. 2008
    ..HHV-8-specific T-cell responses are required to achieve posttransplant KS remission, and may be restored under SRL, while maintaining effective immunosuppression...
  53. ncbi request reprint Saliva and the transmission of human herpesvirus 8: potential role of promoter-arthropod bites
    Mario Coluzzi
    J Infect Dis 190:199-200; author reply 200-1. 2004
  54. ncbi request reprint Amino acid residue at position 13 in HLA-DR beta chain plays a critical role in the development of Kaposi's sarcoma in AIDS patients
    Antoni Gayà
    Fundació Banc de Sang i Teixits, Palma de Mallorca, Spain
    AIDS 18:199-204. 2004
    ..In 1994 human herpesvirus 8 (HHV-8) was identified as the causative agent of Kaposi's sarcoma (KS). Moreover, the crucial role of HLA molecules in determining susceptibility to several infections was recognized...