Research Topics
Species | Imke SatzgerSummaryAffiliation: Hannover Medical School Country: Germany Publications
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Detail Information
Publications
microRNA-21 is upregulated in malignant melanoma and influences apoptosis of melanocytic cellsImke Satzger
Department of Dermatology and Allergy, Skin Cancer Center Hannover, Hannover Medical School, Hannover, Germany
Exp Dermatol 21:509-14. 2012..However, in the MEWO melanoma cells with low endogenous miR-21 expression, upregulation of miR-21 had no functional effects. These findings indicate a potential pathogenetic role of miR-21 upregulation in a subgroup of melanomas...
Sentinel node dissection delays recurrence and prolongs melanoma-related survival: an analysis of 673 patients from a single center with long-term follow-upI Satzger
Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany
Ann Surg Oncol 18:514-20. 2011..A large series of melanoma patients from a single center with long-term follow-up was analyzed with regard to a possible effect of SLND on the prognosis...
MicroRNA-15b represents an independent prognostic parameter and is correlated with tumor cell proliferation and apoptosis in malignant melanomaImke Satzger
Department of Dermatology and Allergy, Skin Cancer Center Hannover, Hannover Medical School, Hannover, Germany
Int J Cancer 126:2553-62. 2010..MiR-15b appears to represent a particular important miRNA in melanoma that is associated with poor prognosis and tumorigenesis...
Analysis of c-KIT expression and KIT gene mutation in human mucosal melanomasI Satzger
Department of Dermatology and Allergology, Skin Cancer Center Hannover, Hannover Medical School, Hannover, Germany
Br J Cancer 99:2065-9. 2008..Our data encourage therapeutic attempts with tyrosine kinase inhibitors blocking c-KIT in these patients...
[Intravascular lymphoma: two case reports demonstrating the heterogeneity of the disease]I Satzger
Klinik und Poliklinik fur Dermatologie und Venerologie, Medizinische Hochschule Hannover, Hauttumorzentrum Hannover HTZH, Ricklinger Strasse 5, Hannover, Germany
Hautarzt 60:131-6. 2009..The other patient had distinctive cutaneous and neurological symptoms which did not respond to therapy. By means of these two patients, we present the heterogeneity of IVL and discuss current aspects of diagnosis and treatment...
Criteria in sentinel lymph nodes of melanoma patients that predict involvement of nonsentinel lymph nodesImke Satzger
Department of Dermatology and Allergology, Skin Cancer Center Hannover, Hannover Medical School, Ricklinger Str 5, 30449 Hannover, Germany
Ann Surg Oncol 15:1723-32. 2008..Such criteria may facilitate the selection of patients who might benefit from a completion lymph node dissection (CLND). However, it is currently unclear which parameters are most important...
Prognostic significance of isolated HMB45 or Melan A positive cells in Melanoma sentinel lymph nodesImke Satzger
Department of Dermatology, Skin Cancer Center Hannover, Hannover Medical School, Hannover, Germany
Am J Surg Pathol 31:1175-80. 2007..In conclusion, with short-term follow-up IPC in melanoma SLN are without prognostic significance...
Therapeutic use of erythropoietin in dermatooncologyImke Satzger
Department of Dermatology and Venereology, Skin Tumor Center, Hannover Medical School, Hannover, Germany
J Dtsch Dermatol Ges 5:280-5. 2007..We review here current guidelines on the use of erythropoietin in cancer patients and report on our own melanoma patients treated with erythropoietin for chemotherapy-induced anemia...
Comparison of classification systems in melanoma sentinel lymph nodes--an analysis of 697 patients from a single centerAndre Meier
Department of Dermatology and Allergy, Skin Cancer Center Hannover, Hannover Medical School, Hannover, Germany
Cancer 116:3178-88. 2010..The authors of this report compared the RFS and OS of 697 melanoma patients as predicted by various classification systems...
Age as a key factor influencing metastasizing patterns and disease-specific survival after sentinel lymph node biopsy for cutaneous melanomaLutz Kretschmer
Department of Dermatology, Venereology and Allergology, Georg August University of Goettingen, Gottingen, Germany
Int J Cancer 129:1435-42. 2011..Younger patients have a better prognosis despite their higher probability of SLN metastasis. Older patients are less frequently SLN-positive but have a higher risk of loco-regional recurrence...
Anal mucosal melanoma with KIT-activating mutation and response to imatinib therapy--case report and review of the literatureImke Satzger
Skin Cancer Center Hannover, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany satzger imke mh hannover de
Dermatology 220:77-81. 2010..We report here on one of our patients with KIT-activating mutation in metastatic anal mucosal melanoma, who showed a response to imatinib therapy and summarize the available literature regarding this new therapeutic option...
Sentinel lymph node status is the most important prognostic factor for thick (> or = 4 mm) melanomasRalf Gutzmer
Department of Dermatology and Venereology, Skin Tumor Center Hannover HTZH, Hannover Medical School, Hannover, Germany
J Dtsch Dermatol Ges 6:198-203. 2008..The value of the status of the sentinel lymph node (SLN) in patients with thick melanomas (Breslow thickness > or = 4 mm) is controversial...
The hand-foot-syndrome associated with medical tumor therapy - classification and managementAnnette Degen
Clinic and Polyclinic for Dermatology, and Allergy, Skin Cancer Center Hannover HTZH, Hannover Medical School, Germany
J Dtsch Dermatol Ges 8:652-61. 2010..In this review, similarities and differences between chemotherapy- and MKI-associated HFS are discussed and current recommendations for their prophylaxis and management are summarized...
Autoimmunity as a prognostic factor in melanoma patients treated with adjuvant low-dose interferon alphaImke Satzger
Department of Dermatology and Allergology, Hannover Medical School, Hautklinik Linden, Klinikum Region Hannover, Skin Cancer Center Hannover, Hannover, Germany
Int J Cancer 121:2562-6. 2007..Thus, autoimmunity triggered by low-dose IFN therapy appears to indicate an improved prognosis and should encourage continuation of IFN therapy...
Tumoral melanosis involving the sentinel lymph nodes: a case reportImke Satzger
Department of Dermatology and Allergology, Hannover Medical University, Hannover, Germany
J Cutan Pathol 34:284-6. 2007..We present a patient with nodular melanosis involving also the sentinel lymph nodes and discuss possible differential diagnoses as well as prognostic and therapeutic implications...
Staphylococcal α-toxin induces a higher T cell proliferation and interleukin-31 in atopic dermatitisMargarete Niebuhr
Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany
Int Arch Allergy Immunol 156:412-5. 2011..Patients with atopic dermatitis (AD) are frequently colonized with α-toxin-producing Staphylococcus aureus which is in turn positively correlated with the severity of eczema...
Intrinsic alterations of pro-inflammatory mediators in unstimulated and TLR-2 stimulated keratinocytes from atopic dermatitis patientsMargarete Niebuhr
Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany
Exp Dermatol 20:468-72. 2011..aureus...
Atypical cutaneous herpes virus infection associated with fludarabine chemotherapy of lymphomaImke Satzger
Eur J Dermatol 17:165-6. 2007
Spontaneous regression of melanoma with distant metastases - report of a patient with brain metastasesImke Satzger
Eur J Dermatol 16:454-5. 2006
