Niels Rahe-Meyer

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. pmc Influence of the sample anticoagulant on the measurements of impedance aggregometry in cardiac surgery
    Cristina Solomon
    Department of Anesthesiology, Hannover Medical School, Hannover, Germany
    Med Devices (Auckl) 1:23-30. 2008
  2. doi request reprint Fibrinogen concentrate in the treatment of severe bleeding after aortic aneurysm graft surgery
    Niels Rahe-Meyer
    Clinic for Anesthesiology and Intensive Care Medicine, Hannover, Germany
    Thromb Res 128:S17-9. 2011
  3. ncbi request reprint [Examination of a new tube connector concerning the ventilation-leakage during intraoperative bronchoskopy and bronchal suction]
    N Rahe-Meyer
    Medizinische Hochschule Hannover, Abteilung Anästhesiologie
    Anasthesiol Intensivmed Notfallmed Schmerzther 40:532-5. 2005
  4. pmc Bleeding management with fibrinogen concentrate targeting a high-normal plasma fibrinogen level: a pilot study
    N Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Carl Neuberg Str 1, Hannover D 30625, Germany
    Br J Anaesth 102:785-92. 2009
  5. doi request reprint Thromboelastometry-guided administration of fibrinogen concentrate for the treatment of excessive intraoperative bleeding in thoracoabdominal aortic aneurysm surgery
    Niels Rahe-Meyer
    Department of Anesthesiology, Hannover Medical School, Hannover, Germany
    J Thorac Cardiovasc Surg 138:694-702. 2009
  6. doi request reprint Platelet concentrates transfusion in cardiac surgery and platelet function assessment by multiple electrode aggregometry
    N Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Hannover, Germany
    Acta Anaesthesiol Scand 53:168-75. 2009
  7. doi request reprint An evaluation of cyclooxygenase-1 inhibition before coronary artery surgery: aggregometry versus patient self-reporting
    Niels Rahe-Meyer
    Department of Anesthesiology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Anesth Analg 107:1791-7. 2008
  8. doi request reprint Comparison of breathing tube connectors during invasive bronchial procedures
    N Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Hannover, Germany
    Anaesthesia 64:666-73. 2009
  9. pmc Complex myograph allows the examination of complex muscle contractions for the assessment of muscle force, shortening, velocity, and work in vivo
    Niels Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Carl Neuberg Str, 1, D 30625, Hannover, Germany
    Biomed Eng Online 7:20. 2008
  10. pmc In vivo myograph measurement of muscle contraction at optimal length
    Niels Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Carl Neuberg Str, 1, D 30625 Hannover, Germany
    Biomed Eng Online 6:1. 2007

Collaborators

Detail Information

Publications82

  1. pmc Influence of the sample anticoagulant on the measurements of impedance aggregometry in cardiac surgery
    Cristina Solomon
    Department of Anesthesiology, Hannover Medical School, Hannover, Germany
    Med Devices (Auckl) 1:23-30. 2008
    ....
  2. doi request reprint Fibrinogen concentrate in the treatment of severe bleeding after aortic aneurysm graft surgery
    Niels Rahe-Meyer
    Clinic for Anesthesiology and Intensive Care Medicine, Hannover, Germany
    Thromb Res 128:S17-9. 2011
    ..Results are expected to be published soon. Larger, multicenter studies are needed to determine the exact role of fibrinogen concentrate in the management of perioperative bleeding following cardiac surgery and cardiopulmonary bypass...
  3. ncbi request reprint [Examination of a new tube connector concerning the ventilation-leakage during intraoperative bronchoskopy and bronchal suction]
    N Rahe-Meyer
    Medizinische Hochschule Hannover, Abteilung Anästhesiologie
    Anasthesiol Intensivmed Notfallmed Schmerzther 40:532-5. 2005
    ..This study was undertaken to compare the influence of a newly-developed connecting tube with check valve on these problems...
  4. pmc Bleeding management with fibrinogen concentrate targeting a high-normal plasma fibrinogen level: a pilot study
    N Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Carl Neuberg Str 1, Hannover D 30625, Germany
    Br J Anaesth 102:785-92. 2009
    ..The aim was to compare haemostatic effects of conventional transfusion management and FIBTEM (thromboelastometry test)-guided fibrinogen concentrate administration...
  5. doi request reprint Thromboelastometry-guided administration of fibrinogen concentrate for the treatment of excessive intraoperative bleeding in thoracoabdominal aortic aneurysm surgery
    Niels Rahe-Meyer
    Department of Anesthesiology, Hannover Medical School, Hannover, Germany
    J Thorac Cardiovasc Surg 138:694-702. 2009
    ..We assessed the efficacy of intraoperative post-cardiopulmonary bypass administration of fibrinogen concentrate in elective thoracoabdominal aortic aneurysm surgery...
  6. doi request reprint Platelet concentrates transfusion in cardiac surgery and platelet function assessment by multiple electrode aggregometry
    N Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Hannover, Germany
    Acta Anaesthesiol Scand 53:168-75. 2009
    ..We evaluated the usefulness of the Multiplate platelet function analyser based on impedance aggregometry for identifying groups of patients at a high risk of transfusion of platelet concentrates (PC)...
  7. doi request reprint An evaluation of cyclooxygenase-1 inhibition before coronary artery surgery: aggregometry versus patient self-reporting
    Niels Rahe-Meyer
    Department of Anesthesiology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Anesth Analg 107:1791-7. 2008
    ..Our objective was to compare the assessment of aspirin intake by patient self-reporting and by measurement of platelet function with regard to transfusion requirements...
  8. doi request reprint Comparison of breathing tube connectors during invasive bronchial procedures
    N Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Hannover, Germany
    Anaesthesia 64:666-73. 2009
    ..The connectors showed different ranges of tightness, equivalent to different ranges of compatibility with the instruments used...
  9. pmc Complex myograph allows the examination of complex muscle contractions for the assessment of muscle force, shortening, velocity, and work in vivo
    Niels Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Carl Neuberg Str, 1, D 30625, Hannover, Germany
    Biomed Eng Online 7:20. 2008
    ....
  10. pmc In vivo myograph measurement of muscle contraction at optimal length
    Niels Rahe-Meyer
    Department of Anaesthesiology, Hannover Medical School, Carl Neuberg Str, 1, D 30625 Hannover, Germany
    Biomed Eng Online 6:1. 2007
    ..Consequently, for clinical testing only semi-quantitative methods have been used...
  11. pmc Assessment of precision and reproducibility of a new myograph
    Niels Rahe-Meyer
    Department of Anesthesiology, Hannover Medical School, Carl Neuberg Str, 1, D 30625 Hannover, Germany
    Biomed Eng Online 6:49. 2007
    ..Other devices, which obtain standard muscle contractions by electric stimulations, do not have the technology required to induce and measure reproducible valid contractions at the optimum muscle length...
  12. doi request reprint Significance of infection markers and microbiological findings during tissue processing of cryopreserved arterial homografts for the early postoperative course
    T E Bisdas
    Hannover Medical School, Dept of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover, Germany
    Vasa 38:365-73. 2009
    ..To evaluate homograft implantation for the urgent treatment of vascular infections on the basis of the course of infection using microbiological findings in perioperatively obtained specimens and during homograft processing...
  13. doi request reprint Human iliac vein replacement with a tissue-engineered graft
    O E Teebken
    Hannover Medical School, Dept of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover, Germany
    Vasa 38:60-5. 2009
    ..Tissue engineered neo-veins may be a therapeutic option in selected cases with symptomatic vein stenosis or obstruction not curable with interventional methods or standard prosthetic replacement...
  14. ncbi request reprint Heart valves from pigs and the porcine endogenous retrovirus: experimental and clinical data to assess the probability of porcine endogenous retrovirus infection in human subjects
    A K Moza
    Leibniz Research Laboratories for Biotechnology and Artificial Organs LEBAO, Hannover, Germany
    J Thorac Cardiovasc Surg 121:697-701. 2001
    ....
  15. ncbi request reprint Tissue engineering of heart valves--human endothelial cell seeding of detergent acellularized porcine valves
    A Bader
    Leibniz Research Laboratories for Biotechnology and Artificial Organs, LEBAO, Hannover Medical School, Germany
    Eur J Cardiothorac Surg 14:279-84. 1998
    ..The aim of this study was to develop a new methodology for a tissue engineered heart valve combining human cells and a xenogenic acellularized matrix...
  16. ncbi request reprint Pulsatile perfusion and cardiomyocyte viability in a solid three-dimensional matrix
    T Kofidis
    Department of Thoracic and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
    Biomaterials 24:5009-14. 2003
    ..We introduce a novel concept of pulsatile tissue culture perfusion to promote ubiquitous cellular viability and metabolism...
  17. ncbi request reprint Lung transplantation--10-year experience
    W Harringer
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany
    Eur J Cardiothorac Surg 16:546-54. 1999
    ..The experience at our institution with various forms of lung transplantation (heart-lung, double lung and single lung) from December 1987 to September 1998 is reviewed and discussed...
  18. doi request reprint A biological alternative to alloplastic grafts in dialysis therapy: evaluation of an autologised bioartificial haemodialysis shunt vessel in a sheep model
    S Koenneker
    Center of Competence for Cardiovascular Implants Medimplant, Department of Cardiac Surgery, Hannover Medical School, Hannover, Germany
    Eur J Vasc Endovasc Surg 40:810-6. 2010
    ..To evaluate bioartificial haemodialysis access grafts in a sheep model with respect to patency and morphology...
  19. doi request reprint A staged approach towards interventional aortic valve implantation with a sutureless valve: initial human implants
    M Shrestha
    Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
    Thorac Cardiovasc Surg 56:398-400. 2008
    ..The purpose of this study was to assess a new sutureless aortic valve (Perceval Sorin). As a first step, an open approach using cardiopulmonary bypass (CPB) was chosen to evaluate the feasibility of implantation...
  20. ncbi request reprint No evidence for productive PERV infection of baboon cells in in vivo infection model
    A R Simon
    Leibniz Research Laboratories for Biotechnology and Artificial Organs, Department of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany
    Ann Transplant 8:24-34. 2003
    ..However, it is still open to discussion, whether non-human primate cells can be infected productively-similar to human cells- and whether those species are suitable to analyze PERV infection risks in vivo...
  21. doi request reprint Preclinical development of tissue-engineered vein valves and venous substitutes using re-endothelialised human vein matrix
    O E Teebken
    Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
    Eur J Vasc Endovasc Surg 37:92-102. 2009
    ..This technique may enable causal treatment of venous reflux and obstructions...
  22. ncbi request reprint Improvement of pulmonary preservation with Celsior and Perfadex: impact of storage time on early post-ischemic lung function
    T Wittwer
    Department of Cardiothoracic and Vascular Surgery, Hannover Medical School, Germany
    J Heart Lung Transplant 18:1198-201. 1999
    ..Optimal preservation of post-ischemic organ function is a continuing challenge in clinical lung transplantation...
  23. ncbi request reprint Mechanism of luminal narrowing in cardiac allograft vasculopathy: inadequate vascular remodeling rather than intimal hyperplasia is the major predictor of coronary artery stenosis. Working Group on Cardiac Allograft Vasculopathy
    K Pethig
    Department of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany
    Am Heart J 135:628-33. 1998
    ..Despite increasing knowledge about degree and distribution pattern of intimal hyperplasia in cardiac allograft vasculopathy, coronary artery remodeling is only poorly understood in this disease...
  24. ncbi request reprint Improved right ventricular function after intracoronary administration of a C1 esterase inhibitor in a right heart transplantation model
    U Klima
    Department of Thoracic and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
    Eur J Cardiothorac Surg 18:321-7. 2000
    ..Our study addresses the question whether the most susceptible region of the heart for ischemic injury, the right ventricle (RV), can benefit from the protective effects of C1 esterase inhibition after transplantation...
  25. ncbi request reprint Effects of the ABO-mismatch between donor and recipient of cryopreserved arterial homografts
    T Bisdas
    Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover, Germany
    Int Angiol 30:247-55. 2011
    ..We compared the outcome between ABO-compatible and ABO-incompatible CAH recipients to evaluate the contribution of ABO-mismatching...
  26. ncbi request reprint Porcine endogenous retrovirus (PERV) was not transmitted from transplanted porcine endothelial cells to baboons in vivo
    U Martin
    Leibniz Research Laboratories for Biotechnology and Artificial Organs, Hannover Medical School, Germany
    Transpl Int 11:247-51. 1998
    ..In spite of the release of retroviral particles from cultured PAEC, transplantation of these cells into baboon recipients did not result in virus transmission, not even under heavy immunosuppression...
  27. doi request reprint Fibrinogen concentrate reduces intraoperative bleeding when used as first-line hemostatic therapy during major aortic replacement surgery: results from a randomized, placebo-controlled trial
    Niels Rahe-Meyer
    Clinic for Anesthesiology and Intensive Care Medicine, Franziskus Hospital, Bielefeld, Germany
    J Thorac Cardiovasc Surg 145:S178-85. 2013
    ..We assessed whether fibrinogen concentrate as targeted first-line hemostatic therapy was more effective than placebo or a standardized transfusion algorithm in controlling coagulopathic bleeding in patients undergoing major aortic surgery...
  28. ncbi request reprint Valve-sparing repair after aortic root dissection following heart transplantation
    O E Teebken
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany
    J Heart Lung Transplant 18:807-9. 1999
    ..Surgical therapy included replacement of the ascending aorta with an aortic allograft and implantation of the native aortic valve inside the allograft as a modified David procedure...
  29. ncbi request reprint [A xenogeneic acellularized matrix for heart valve tissue engineering: in vivo study in a sheep model]
    R Leyh
    Abteilung Thorax Herz und Gefässchirurgie, Medizinische Hochschule Hannover, Carl Neuberg Str 1, 30623 Hannover, Germany
    Z Kardiol 92:938-46. 2003
    ..We evaluated acellularized xenogenic matrix constructs with and without seeding with autologous vascular cells in the pulmonary circulation in a sheep model...
  30. doi request reprint Extracorporeal membrane oxygenation in nonintubated patients as bridge to lung transplantation
    K M Olsson
    Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany
    Am J Transplant 10:2173-8. 2010
    ..All of them made a full recovery after transplantation, which demonstrates the feasibility of using ECMO support in nonintubated patients with cardiopulmonary failure as a bridging strategy to lung transplantation...
  31. ncbi request reprint Volumetric remodeling of the proximal left coronary artery: early versus late after heart transplantation
    K Pethig
    Department of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany
    J Am Coll Cardiol 34:197-203. 1999
    ..The aim of this study was to characterize progression of cardiac allograft vasculopathy (CAV) with special respect to coronary artery geometry...
  32. doi request reprint Hypothermic circulatory arrest with "low flow" lower body perfusion: an experimental feasibility study of microcirculatory parameters
    S Peterss
    Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
    Thorac Cardiovasc Surg 59:335-41. 2011
    ..Distal aortic perfusion may be an option, but supportive experimental data is missing...
  33. ncbi request reprint Replacement of ascending aorta with aortic valve reimplantation: midterm results
    W Harringer
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany
    Eur J Cardiothorac Surg 15:803-7; discussion 807-8. 1999
    ..Durability of this valve repair with respect to increased mechanical stress on valve cusps is discussed controversially and is yet unknown...
  34. ncbi request reprint Clinically established hemostatic scaffold (tissue fleece) as biomatrix in tissue- and organ-engineering research
    T Kofidis
    Division of Thoracic and Cardiovascular Surgery and Leibniz Research Laboratories for Biotechnology and Artificial Organs LEBAO, Hannover Medical School, Hannover, Germany
    Tissue Eng 9:517-23. 2003
    ..Tissue Fleece constitutes an effective scaffold to engineer solid organ structures, which could be used for repair of congenital defects or replacement of diseased tissue...
  35. ncbi request reprint Ascending aortic replacement with aortic valve reimplantation
    W Harringer
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
    Circulation 100:II24-8. 1999
    ..The durability of this valve repair with respect to the increased mechanical stress on valve cusps has been discussed, is quite controversial, and is yet unknown...
  36. doi request reprint Treatment of acute aortic dissection type A (AADA): technical considerations
    Christian Hagl
    Hannover Medical School, Hannover, Germany
    Vasa 39:212-8. 2010
    ..The current manuscript raises important issues regarding surgical treatment of AADA patients which are discussed in the light of the institutional policy in the author's department...
  37. ncbi request reprint Systemic inflammatory response in cardiac allograft vasculopathy: high-sensitive C-reactive protein is associated with progressive luminal obstruction
    K Pethig
    Department of Thoracic and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
    Circulation 102:III233-6. 2000
    ..Although histopathologic examinations reveal signs of focal inflammation, little is known about the systemic inflammatory response in this accelerated coronary syndrome...
  38. ncbi request reprint Acellularized porcine heart valve scaffolds for heart valve tissue engineering and the risk of cross-species transmission of porcine endogenous retrovirus
    R G Leyh
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Carl Neuberg St 1, 30623 Hannover, Germany
    J Thorac Cardiovasc Surg 126:1000-4. 2003
    ..In this study we investigated whether acellularized porcine heart valve scaffold causes cross-species transmission of porcine endogenous retrovirus in a sheep model...
  39. ncbi request reprint Human cytokine responses to coronary artery bypass grafting with and without cardiopulmonary bypass
    M Struber
    Department of Anesthesia, Hannover Medical School, Germany
    Ann Thorac Surg 68:1330-5. 1999
    ..This study compares the inflammatory response after CABG with cardiopulmonary bypass and after minimally invasive direct coronary artery bypass grafting (MIDCABG) without cardiopulmonary bypass...
  40. ncbi request reprint Matched-pair analysis of conventional versus endoluminal AAA treatment outcomes during the initial phase of an aortic endografting program
    T U Cohnert
    Department of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany
    J Endovasc Ther 7:94-100. 2000
    ..To investigate whether endovascular stent-grafts implanted during the early phase of an aortic endografting program have advantages over conventional surgical procedures for treatment of infrarenal aortic aneurysm (AAA)...
  41. ncbi request reprint Low-potassium dextran solution ameliorates reperfusion injury of the lung and protects surfactant function
    M Struber
    Division of Thoracic and Cardiovascular Surgery and the Department of Pneumology, Hannover Medical School, Hannover, Germany
    J Thorac Cardiovasc Surg 120:566-72. 2000
    ..This study was designed to compare the effect of lung preservation with low-potassium dextran solution and Euro-Collins solution on reperfusion injury and surfactant function by using an in situ model of warm ischemia...
  42. ncbi request reprint Surfactant replacement in reperfusion injury after clinical lung transplantation
    M Struber
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Carl Neuberg Str 1, 30623 Hannover, Germany
    Intensive Care Med 25:862-4. 1999
    ..We report on our initial clinical experience of surfactant replacement in reperfusion injury after clinical lung transplantation...
  43. ncbi request reprint Impact of vascular branching sites on focal progression of allograft vasculopathy in transplanted hearts
    K Pethig
    Department of Thoracic and Cardiovascular Surgery, Division of Surgery, Hannover Medical School, D 30623 Hannover, Germany
    Atherosclerosis 158:155-60. 2001
    ..As a model for differences in focal blood flow dynamics, we analyzed progression of intimal hyperplasia at vascular bifurcational sites using intravascular ultrasound (IVUS)...
  44. ncbi request reprint Enhanced oxygen delivery reverses anaerobic metabolic states in prolonged sandwich rat hepatocyte culture
    A Bader
    Leibniz Laboratories of Biotechnology and Artificial Organs, Medizinische Hochschule Hannover, Hannover, 30659, Germany
    Exp Cell Res 246:221-32. 1999
    ..The long-term culture of hepatocytes on oxygenating supports at in vivo-like oxygen tensions therefore appears to be more physiologic and beneficial for the cells...
  45. ncbi request reprint Inhaled nitric oxide and inhaled prostaglandin E1: effect on left ventricular contractility when used for treatment of experimental pulmonary hypertension
    P Krieg
    Department of Cardiothoracic and Vascular Surgery, Hannover Medical School, Germany
    Eur J Cardiothorac Surg 14:494-502. 1998
    ..Recent work has shown that inhaled nitric oxide (NO) in combination with inhaled prostaglandin E1 (PGE1) reduce pulmonary hypertension but their influence on cardiac contractility is less well defined...
  46. ncbi request reprint Expression of pig endogenous retrovirus by primary porcine endothelial cells and infection of human cells
    U Martin
    Leibniz Research Laboratories for Biotechnology and Artificial Organs, Hannover Medical School, Germany
    Lancet 352:692-4. 1998
    ..Endothelial cells are the main interface between a xenograft and the recipient's leucocytes and tissues...
  47. ncbi request reprint Role of inflammation and ischemia after implantation of xenogeneic pulmonary valve conduits: histological evaluation after 6 to 12 months in sheep
    M H Wilhelmi
    Division of Thoracic, and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
    Int J Artif Organs 26:411-20. 2003
    ..Here we evaluate the role of inflammation and ischemia after implantation of xenogeneic heart valve conduits (XPC) generated by novel concepts of tissue engineering...
  48. ncbi request reprint Cell seeded decellularised allogeneic matrix grafts and biodegradable polydioxanone-prostheses compared with arterial autografts in a porcine model
    O E Teebken
    Leibniz Research Laboratories for Biotechnology and Artificial Organs, LEBAO, Hannover, Germany
    Eur J Vasc Endovasc Surg 22:139-45. 2001
    ..CONCLUSION: small diameter vascular grafts can be engineered from an acellular allogeneic matrix seeded with autologous cells. Patency is superior to polydioxanone prostheses but inferior to the arterial autograft...
  49. pmc Progression of cardiac allograft vascular disease as assessed by serial intravascular ultrasound: correlation to immunological and non-immunological risk factors
    K Pethig
    Department of Thoracic and Cardiovascular Surgery, Division of Surgery, Hannover Medical School, D 30623 Hannover, Germany
    Heart 84:494-8. 2000
    ..To characterise the severity and progression of cardiac allograft vascular disease (CAVD) in a large patient cohort, and to evaluate possible immunological and non-immunological risk factors for progression...
  50. ncbi request reprint [In vivo detection of integration of grafted cells after myocardial transplantation]
    A Ruhparwar
    Abteilung für Thorax, Herz und Gefässchirurgie, Medizinische Hochschule Hannover, Carl Neuberg Str 1, 30625 Hannover
    Zentralbl Chir 131:420-4. 2006
    ..Further technical adjustments should allow for thoracoscopic/endoscopic application of this method, making it appropriate for use in other organs and in clinical studies...
  51. ncbi request reprint Minimally invasive removal of a dislocated stent from the right atrium after previous CABG
    T Walles
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany
    Ann Thorac Surg 72:1382-4. 2001
    ..We report a case of successful minimally invasive removal of a dislocated subclavian vein stent entangled in the tricuspid valve in a patient 5 years after coronary artery bypass surgery...
  52. doi request reprint [Tissue engineering of vascularized myocardial prosthetic tissue. Biological and solid matrices]
    T Schilling
    Klinik fur Herz, Thorax, Transplantations und Gefäßchirurgie, Medizinischen Hochschule Hannover, Carl Neuberg Strasse 1, Hannover, Germany
    Chirurg 82:319-24. 2011
    ....
  53. ncbi request reprint [Modified endothelial cells in graft vasculopathy]
    A Haverich
    Klinik fur Thorax, Herz und Gefässchirurgie Carl Neuberg Str 1, 30625 Hannover, Germany
    Z Kardiol 90:939-45. 2001
    ..First results of large animal studies show promising results and may lead to the first clinical trials in the near future...
  54. ncbi request reprint Severe obstructive calcifications affecting the descending and suprarenal abdominal aorta without coexisting peripheral atherosclerotic disease--coral reef aorta
    O E Teebken
    Department of Thoracic and Cardiovascular Surgery, Hannover Medical School, OE 6210 Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    Vasa 35:206-8. 2006
    ..In case of future visceral or left renal malperfusion the diseased artery can be connected to the prosthesis directly or by the use of an additional bypass graft. This would not be the case with a conventional axillo-bifemoral graft...
  55. doi request reprint Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial
    Niels Rahe-Meyer
    Clinic for Anesthesiology and Intensive Care Medicine, Franziskus Hospital, Bielefeld, Germany
    Anesthesiology 118:40-50. 2013
    ..The authors assessed whether fibrinogen concentrate can reduce blood transfusion when given as intraoperative, targeted, first-line hemostatic therapy in bleeding patients undergoing aortic replacement surgery...
  56. doi request reprint Isovolaemic hemodilution with gelatin and hydroxyethylstarch 130/0.42: effects on hemostasis in piglets
    Lars Witt
    Clinic of Anaesthesiology, Hannover Medical School, Hannover, Germany
    Paediatr Anaesth 22:379-85. 2012
    ..To determine the impact of acute isovolaemic hemodilution with artificial colloids on clot formation, we conducted an experimental study in a pediatric animal model...
  57. ncbi request reprint Carotid endarterectomy with or without concomitant aortocoronary bypass in elderly patients: an analysis of 599 procedures
    T Bisdas
    Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
    Int Angiol 29:47-52. 2010
    ..Aim of this study is to report the mid-term (30 days) neurological outcome in patients older than 75 years after CEA with or without simultaneous aortocoronary bypass (CABG)...
  58. ncbi request reprint C1-esterase inhibitor in graft failure after lung transplantation
    M Struber
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany
    Intensive Care Med 25:1315-8. 1999
    ..ECMO was discontinued after C1-INH treatment and the patient extubated 2 weeks later. This experience indicates that C1-INH may play a role in the management of capillary leak syndrome after lung transplantation...
  59. ncbi request reprint Vascular remodeling in cardiac allograft vasculopathy
    K Pethig
    Department of Thoracic and Cardiovascular Surgery, Div of Surgery, Hannover Medical School, 30623 Hannover, Germany
    Z Kardiol 89:IX/36-9. 2000
    ..These observations might be of special interest regarding pathophysiology and potential therapeutic interventions in this unique form of an accelerated coronary syndrome...
  60. ncbi request reprint Outcome following single vs bilateral lung transplantation in recipients 60 years of age and older
    S Fischer
    Hannover Thoracic Organ Transplant Program, Division of Thoracic and Cardiovascular Surgery Hannover Medical School, Hannover, Germany
    Transplant Proc 37:1369-70. 2005
    ..The significant shortage of donor organs in lung transplantation necessitates a careful selection of lung transplant recipients. The outcome of lung transplant recipients aged 60 years and older has not been analyzed systematically...
  61. ncbi request reprint Cardiac allograft vasculopathy--coronary interventions and surgical options
    K Pethig
    Department of Thoracic and Cardiovascular Surgery, Div of Surgery, Hannover Medical School, 30623 Hannover, Germany
    Z Kardiol 89:IX/66-9. 2000
    ..In selected patients (focal obstruction not suitable for interventional therapy, adequate peripheral vessels) it might represent a therapeutical alternative...
  62. doi request reprint Intentional ABO-incompatible lung transplantation
    M Struber
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
    Am J Transplant 8:2476-8. 2008
    ..Nine months after the transplant the patient is at home and well...
  63. ncbi request reprint [Tissue engineering: in vitro creation of tissue substitutes]
    O E Teebken
    Klinik fur Herz, Thorax, Transplantations und Gefässchirurgie, Medizinische Hochschule Hannover, 30625 Hannover
    Zentralbl Chir 132:236-46. 2007
    ....
  64. doi request reprint The minimized extracorporeal circulation system causes less inflammation and organ damage
    T Kofidis
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
    Perfusion 23:147-51. 2008
    ..It may also be the circuit in patients with chronic obstructive pulmonary disease (COPD)...
  65. doi request reprint New developments in tissue engineering of vascular prosthetic grafts
    T Aper
    Hannover Medical School, Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover, Germany
    Vasa 38:99-122. 2009
    ..This article reviews established bypass materials and provides an overview over interesting new technologies particularly those associated with tissue-engineering and those already adopted clinically...
  66. ncbi request reprint Flush perfusion with low potassium dextran solution improves early graft function in clinical lung transplantation
    M Struber
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Carl Neuberg Strasse 1, 30623Hannover, Germany
    Eur J Cardiothorac Surg 19:190-4. 2001
    ..Now we report on early graft function in 106 lung transplant recipients of LPD or EC preserved grafts...
  67. ncbi request reprint The ex-vivo-shunt-model: novel approach for assessing the thrombogenicity of vascular implants
    M H Wilhelmi
    Division for Thoracic, and Cardiovascular Surgery, Hannover Medical School, Germany
    Int J Artif Organs 26:1095-103. 2003
    ..Although many tissue characterizing strategies have been defined, no valid test for thrombogenicity exists. Here we introduce a novel concept for thrombogenicity testing of vascular implants..
  68. doi request reprint Comparative assessment of coagulation changes induced by two different types of heart-lung machine
    Niels Rahe-Meyer
    Department of Anesthesiology, Hannover Medical School, Hannover, Germany
    Artif Organs 34:3-12. 2010
    ..01, ProcMixed test). Our findings suggest that MEA and thromboelastometry reflect impairment of coagulation in cardiac surgery performed on different types of HLM and that platelet function is less affected by MECC than by standard HLM...
  69. ncbi request reprint Effectiveness and safety of internal rectilinear biphasic versus monophasic defibrillation in patients undergoing cardiac surgery
    Michael Winterhalter
    Department of Anesthesiology, Hannover Medical School, Hannover, Germany
    J Cardiothorac Vasc Anesth 19:739-45. 2005
    ..The purpose of this study was to compare monophasic with rectilinear biphasic internal shock waveforms for termination of VF in patients undergoing cardiac surgery...
  70. doi request reprint Haemostatic therapy in coronary artery bypass graft patients with decreased platelet function: comparison of fibrinogen concentrate with allogeneic blood products
    Cristina Solomon
    Department of Anaesthesiology and Intensive Care Medicine, SALK University Hospital, Salzburg, Austria
    Scand J Clin Lab Invest 72:121-8. 2012
    ..We compared patient outcomes following fibrinogen concentrate administration or transfusion of allogeneics in CABG patients with decreased platelet function...
  71. doi request reprint Platelet concentrates transfusion in cardiac surgery in relation to preoperative point-of-care assessment of platelet adhesion and aggregation
    Cristina Solomon
    Department of Anaesthesiology und Intensive Care, Hannover Medical School, Hannover, Germany
    Platelets 21:221-8. 2010
    ..47 and -0.62, p < 0.05). Multiple electrode aggregometry appeared more useful and easier to apply than CPA for preoperatively identifying patients with platelet concentrates transfusion in cardiac surgery...
  72. ncbi request reprint Prospective investigation into the influence of various stressors on skin impedance
    Michael Winterhalter
    Department of Anaesthesiology, Hannover Medical School, Hanover, Germany
    J Clin Monit Comput 22:67-74. 2008
    ..The aim of the present study was to investigate the influence which different stressors and measurement electrodes have upon skin impedance...
  73. doi request reprint The effects of fibrinogen levels on thromboelastometric variables in the presence of thrombocytopenia
    Thomas Lang
    Department of Anesthesiology, Medical School, Hannover, Germany
    Anesth Analg 108:751-8. 2009
    ..In this study, we investigated the effect of fibrinogen concentration and its relative contribution to overall clot strength using ROTEM...
  74. doi request reprint Skin impedance correlates to sedation grade, plasma propofol concentrations and bispectral index during a target-controlled infusion of propofol
    Michael Winterhalter
    Department of Anaesthesiology, University of Duesseldorf, Duesseldorf, Germany
    Eur J Anaesthesiol 26:589-96. 2009
    ..The aim of this prospective study was to evaluate electrical skin impedance in comparison with bispectral index values and the Observer's Assessment of Alertness and Sedation (OAAS) scale during propofol infusion...
  75. doi request reprint Potential of whole blood coagulation reconstitution by desmopressin and fibrinogen under conditions of hypothermia and acidosis--an in vitro study using rotation thrombelastometry
    Alexander A Hanke
    Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
    Scand J Clin Lab Invest 71:292-8. 2011
    ..Desmopressin (DDAVP) and fibrinogen improve platelet function and clot stability. We investigated the influence of DDAVP and fibrinogen on whole blood coagulation in an in vitro model of hypothermia and acidosis...
  76. doi request reprint Comparison of inhaled iloprost and nitric oxide in patients with pulmonary hypertension during weaning from cardiopulmonary bypass in cardiac surgery: a prospective randomized trial
    Michael Winterhalter
    Department of Anesthesiology, Hannover Medical School, Hannover, Germany
    J Cardiothorac Vasc Anesth 22:406-13. 2008
    ..The objective of this study was to compare the efficacy of inhaled iloprost and nitric oxide (iNO) in reducing pulmonary hypertension (PHT) during cardiac surgery immediately after weaning from cardiopulmonary bypass (CPB)...
  77. doi request reprint Whole blood coagulation measured by modified thrombelastography (ROTEM) is impaired in infants with congenital heart diseases
    Wilhelm Alexander Osthaus
    Anesthetic Center, Department of Pediatric Cardiology and Intensive Care, Medical University of Hannover, Germany
    Blood Coagul Fibrinolysis 19:220-5. 2008
    ..Preoperative hyperfibrinolysis detected with TEM seems to play no important role...
  78. ncbi request reprint Abnormality in the self-monitoring mechanism in patients with fibromyalgia and somatoform pain disorder
    Matthias Karst
    Department of Anesthesiology, Pain Clinic, Hannover Medical School, D 30625 Hannover, Germany
    Psychosom Med 67:111-5. 2005
    ..It is unclear if chronic central pain disorders such as fibromyalgia and somatoform pain disorders also involve a defect of the self-monitoring mechanism...
  79. doi request reprint Multicentric comparison of single portion reagents and liquid reagents for thromboelastometry
    Niels Rahe-Meyer
    Department of Anesthesia, Hannover Medical School, 30625 Hannover, Germany
    Blood Coagul Fibrinolysis 20:218-22. 2009
    ..85-0.99). The SPR reagents showed excellent stability against thermic stress and the measurements were easier to perform than with the conventional liquid reagents system...
  80. pmc Incidence of epileptiform EEG activity in children during mask induction of anaesthesia with brief administration of 8% sevoflurane
    Barbara Schultz
    Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
    PLoS ONE 7:e40903. 2012
    ..It was hypothesized that no epileptiform activity would occur, when the inhaled sevoflurane concentration would be reduced from 8% to 4% immediately after the loss of consciousness...
  81. pmc Platelet activation suppresses HIV-1 infection of T cells
    Theodros Solomon Tsegaye
    Institute of Virology, Hannover Medical School, Hannover, Germany
    Retrovirology 10:48. 2013
    ..Platelets, anucleate cell fragments abundant in human blood, can capture HIV-1 and platelet counts have been associated with viral load and disease progression. However, the impact of platelets on HIV-1 infection of T cells is unclear...
  82. ncbi request reprint Delivery of a healthy child 30 weeks after resuscitation for thromboembolism and treatment with danaparoid: 5-year follow up
    Christian Weilbach
    J Perinat Med 34:505-6. 2006