L Pape

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. doi request reprint The use of transient elastography and non-invasive serum markers of fibrosis in pediatric liver transplant recipients
    Imeke Goldschmidt
    Pediatric Gastroenterology and Hepatology, Department for Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    Pediatr Transplant 17:525-34. 2013
  2. doi request reprint Different models of transition to adult care after pediatric kidney transplantation: a comparative study
    L Pape
    Department of Pediatric Nephrology, Hepatology and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    Pediatr Transplant 17:518-24. 2013
  3. doi request reprint The influence of low donor age, living related donation and pre-emptive transplantation on end-organ damage based on arterial hypertension after paediatric kidney transplantation
    Nele Anne Heidotting
    Department of Pediatric Nephrology, Hannover Medical School, Hannover, Germany
    Nephrol Dial Transplant 27:1672-6. 2012
  4. doi request reprint Pediatric kidney transplantation followed by de novo therapy with everolimus, low-dose cyclosporine A, and steroid elimination: 3-year data
    Lars Pape
    Department of Pediatric Nephrology, Hannover Medical School, Hannover, Germany
    Transplantation 92:658-62. 2011
  5. doi request reprint De novo therapy with everolimus, low-dose ciclosporine A, basiliximab and steroid elimination in pediatric kidney transplantation
    L Pape
    Department of Pediatric Nephrology, Medical School of Hannover, Hannover, Germany
    Am J Transplant 10:2349-54. 2010
  6. ncbi request reprint Long-term follow-up of pediatric transplant recipients: mycophenolic acid trough levels are not a good indicator for long-term graft function
    L Pape
    Department of Pediatric Nephrology, Medical School of Hannover, Hannover, Germany
    Clin Transplant 18:576-9. 2004
  7. doi request reprint Protocol biopsy-driven interventions after pediatric renal transplantation
    N K Kanzelmeyer
    Department of Pediatrics, Hannover Medical School, Hannover, Germany
    Pediatr Transplant 14:1012-8. 2010
  8. ncbi request reprint Alterations of cyclosporin A metabolism induced by mycophenolate mofetil
    L Pape
    Department of Pediatric Nephrology, Medical School of Hannover, Carl Neuberg Strasse 1, D 30627 Hannover, Germany
    Pediatr Transplant 7:302-4. 2003
  9. ncbi request reprint Superior long-term graft function and better growth of grafts in children receiving kidneys from paediatric compared with adult donors
    L Pape
    Department of Pediatric Nephrology, Visceral and Transplant Surgery, Medical School of Hannover, Germany
    Nephrol Dial Transplant 21:2596-600. 2006
  10. ncbi request reprint Living related kidney donation as an advantage for growth of children independent of glomerular filtration rate
    L Pape
    Department of Pediatric Nephrology, Medical School of Hannover, Hannover, Germany
    Transplant Proc 38:685-7. 2006

Collaborators

Detail Information

Publications17

  1. doi request reprint The use of transient elastography and non-invasive serum markers of fibrosis in pediatric liver transplant recipients
    Imeke Goldschmidt
    Pediatric Gastroenterology and Hepatology, Department for Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    Pediatr Transplant 17:525-34. 2013
    ..Normal or cutoff values for pathological degrees of fibrosis cannot be transferred from non-transplanted children. Follow-up studies, preferably with protocol biopsies, might help to improve the diagnostic quality of TE. ..
  2. doi request reprint Different models of transition to adult care after pediatric kidney transplantation: a comparative study
    L Pape
    Department of Pediatric Nephrology, Hepatology and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    Pediatr Transplant 17:518-24. 2013
    ..This was not associated with a lower increase in GFR one yr after transition. Long-term results are awaited...
  3. doi request reprint The influence of low donor age, living related donation and pre-emptive transplantation on end-organ damage based on arterial hypertension after paediatric kidney transplantation
    Nele Anne Heidotting
    Department of Pediatric Nephrology, Hannover Medical School, Hannover, Germany
    Nephrol Dial Transplant 27:1672-6. 2012
    ..To date, no study has described the pre-transplant and transplant risk factors for end-organ damage based on arterial hypertension in children after kidney transplantation (KTX)...
  4. doi request reprint Pediatric kidney transplantation followed by de novo therapy with everolimus, low-dose cyclosporine A, and steroid elimination: 3-year data
    Lars Pape
    Department of Pediatric Nephrology, Hannover Medical School, Hannover, Germany
    Transplantation 92:658-62. 2011
    ..Previously, we initiated a prospective trial to evaluate an immunosuppressive regimen designed to achieve this goal. Herein, we present the results of the 3-year follow-up of this trial...
  5. doi request reprint De novo therapy with everolimus, low-dose ciclosporine A, basiliximab and steroid elimination in pediatric kidney transplantation
    L Pape
    Department of Pediatric Nephrology, Medical School of Hannover, Hannover, Germany
    Am J Transplant 10:2349-54. 2010
    ..Further follow up is needed. Future larger trials will have to confirm our findings...
  6. ncbi request reprint Long-term follow-up of pediatric transplant recipients: mycophenolic acid trough levels are not a good indicator for long-term graft function
    L Pape
    Department of Pediatric Nephrology, Medical School of Hannover, Hannover, Germany
    Clin Transplant 18:576-9. 2004
    ..MMF has also proved successful in improving long-term graft function in patients with chronic allograft nephropathy (CAN). However, no data for long-term monitoring of MPA in children have yet been published...
  7. doi request reprint Protocol biopsy-driven interventions after pediatric renal transplantation
    N K Kanzelmeyer
    Department of Pediatrics, Hannover Medical School, Hannover, Germany
    Pediatr Transplant 14:1012-8. 2010
    ..The performance of protocol biopsies followed by a standardized treatment algorithm led to better graft function 3.5 yr after transplantation. Prospective randomized studies to confirm our findings are needed...
  8. ncbi request reprint Alterations of cyclosporin A metabolism induced by mycophenolate mofetil
    L Pape
    Department of Pediatric Nephrology, Medical School of Hannover, Carl Neuberg Strasse 1, D 30627 Hannover, Germany
    Pediatr Transplant 7:302-4. 2003
    ..According to our findings, we suspect that MMF alters the CsA metabolism. When MMF is used in pediatric transplant recipients, either target values of CsA have to be changed or patients may require higher doses of CsA...
  9. ncbi request reprint Superior long-term graft function and better growth of grafts in children receiving kidneys from paediatric compared with adult donors
    L Pape
    Department of Pediatric Nephrology, Visceral and Transplant Surgery, Medical School of Hannover, Germany
    Nephrol Dial Transplant 21:2596-600. 2006
    ..On the other hand, studies have shown that kidneys of adult donors transplanted into children down-regulate filtration after transplantation and may not increase their function to the need of the growing child...
  10. ncbi request reprint Living related kidney donation as an advantage for growth of children independent of glomerular filtration rate
    L Pape
    Department of Pediatric Nephrology, Medical School of Hannover, Hannover, Germany
    Transplant Proc 38:685-7. 2006
    ..Better growth seems to be an additional factor supporting the policy of LRD kidney transplantation as the best option in children...
  11. ncbi request reprint Cyclosporine in pediatric kidney transplantation
    L Pape
    Department of Pediatric Nephrology, Medical School of Hannover, Hannover, Germany
    Transplant Proc 36:203S-207S. 2004
    ..Combination with mycophenolate mofetil reduces the appearance of chronic rejection. Additional therapy with ToR inhibitors might enforce a reduction of CsA doses and therefore lead to a reduction of CsA toxic effects...
  12. ncbi request reprint Nodular B-cell aggregates associated with treatment refractory renal transplant rejection resolved by rituximab
    A Lehnhardt
    Department of Pediatric Nephrology, Hepatology and Metabolic Diseases, Hannover Medical School, D 30623 Hannover, Germany
    Am J Transplant 6:847-51. 2006
    ..Single dose rituximab may effectively reverse even long-lasting refractory rejection...
  13. ncbi request reprint Long-term stable glomerular filtration rate achieved with tacrolimus in pediatric renal transplantation
    L Pape
    Pediatric Nephrology, Medical School of Hannover, Hannover, Germany
    Transplant Proc 34:2211-2. 2002
  14. ncbi request reprint Cyclosporin A monitoring by 2-h levels: preliminary target levels in stable pediatric kidney transplant recipients
    L Pape
    Department of Pediatric Nephrology, Medical School of Hannover, Hannover, Germany
    Clin Transplant 17:546-8. 2003
    ..An upper target level above 1000 ng/mL should be avoided. The question, whether C2 monitoring in pediatric kidney recipients is superior to C0 monitoring, is yet to be answered...
  15. ncbi request reprint State of pediatric kidney transplantation in 2011
    N K Kanzelmeyer
    Department of Pediatric Kidney, Hannover Medical School, Hannover, Germany
    Minerva Pediatr 64:205-11. 2012
    ..The main challenge, however, concerns chronic humoral transplant rejection, therapy for recurrence of the underlying disease, and the execution of AB0 incompatible transplantations...
  16. ncbi request reprint Growth in children after kidney transplantation with living related donor graft or cadaveric graft
    L Pape
    Department of Paediatric Nephrology, Medical School of Hannover, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    Lancet 366:151-3. 2005
    ..GFR and other factors did not affect height 5 years after transplantation. These findings support use of LRD as the preferred option in children...
  17. ncbi request reprint A single center clinical experience in intensive care management of 104 pediatric renal transplantations between 1998 and 2002
    L Pape
    Department of Pediatric Nephrology, Medical School of Hannover, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    Pediatr Transplant 8:39-43. 2004
    ..General guidelines for postoperative care should be established...