Research Topics
| Matthias OelkeSummaryAffiliation: Hannover Medical School Country: Germany Publications
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Detail Information
Publications
[Pharmacological treatment of benign prostatic hyperplasia]M Oelke
Klinik für Urologie und Urologische Onkologie, Medizinische Hochschule Hannover, Hannover, Deutschland
Urologe A 48:1365-75; quiz 1376-7. 2009..The combination of alpha-blocker plus 5alpha-reductase inhibitor can reduce LUTS and disease progression more effectively than single drugs...
Monotherapy with tadalafil or tamsulosin similarly improved lower urinary tract symptoms suggestive of benign prostatic hyperplasia in an international, randomised, parallel, placebo-controlled clinical trialMatthias Oelke
Department of Urology, Hannover Medical School, Hannover, Germany
Eur Urol 61:917-25. 2012..Tadalafil improved lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH; LUTS/BPH) in clinical studies but has not been evaluated together with an active control in an international clinical study...
Can we identify men who will have complications from benign prostatic obstruction (BPO)? ICI-RS 2011Matthias Oelke
Department of Urology, Hannover Medical School, Hannover, Germany
Neurourol Urodyn 31:322-6. 2012..Research proposals to further enlighten these associations were to be defined...
The fish-hook configuration of the distal ureter indicates bladder outlet obstruction due to benign prostatic hyperplasiaCharalampos Mamoulakis
Department of Urology, University of Crete Medical School, Heraklion, Crete, Greece
World J Urol 29:199-204. 2011..The aim of this retrospective study was to evaluate in a historical series of patients whether morphological changes of the urinary tract imaged on intravenous urography (IVU) are associated with clinical or urodynamic data...
[Is medical therapy useful in the management of stress urinary incontinence?]M Oelke
Klinik für Urologie und Urologische Onkologie, Medizinische Hochschule, Carl Neuberg Strasse 1, 30625 Hannover
Urologe A 48:228-32. 2009..Furthermore, duloxetine could be useful in women to support pelvic floor physiotherapy or in female patients awaiting incontinence surgery...
Manual versus automatic bladder wall thickness measurements: a method comparison studyMatthias Oelke
Department of Urology and Urologic Oncology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
World J Urol 27:747-53. 2009..To compare repeatability and agreement of conventional ultrasound bladder wall thickness (BWT) measurements with automatically obtained BWT measurements by the BVM 6500 device...
Efficacy of propiverine ER with or without α-blockers related to maximum urinary flow rate in adult men with OAB: results of a 12-week, multicenter, non-interventional studyMatthias Oelke
Department of Urology, Hannover Medical School, Carl Neuberg Str 1, 30625, Hannover, Germany
World J Urol 29:217-23. 2011..d. in the treatment of male OAB administered as monotherapy (MT) or add-on to α-blockers (combination treatment, CT) in relation to maximum urinary flow (Q(max)) in a non-interventional study...
[Primary and secondary prevention of benign prostatic hyperplasia: current knowledge and implications for clinical management]M Oelke
Klinik für Urologie und Urologische Onkologie, Medizinische Hochschule Hannover, Carl Neuberg Strase 1, 30625, Hannover, Deutschland
Urologe A 50:1257-8, 1260-4. 2011..Despite several epidemiological and clinical investigations on BPH disease progression no official programme exists in Germany for disease prevention...
[Drug therapy of benign prostatic hyperplasia syndrome with alpha 1-receptor blockers. Basic principles and clinical results]M Oelke
Klinik und Poliklinik für Urologie und Kinderurologie, Medizinische Hochschule, Carl Neuberg Strasse 1, 30625 Hannover
Urologe A 41:425-41. 2002....
Increase in detrusor wall thickness indicates bladder outlet obstruction (BOO) in menMatthias Oelke
Department of Urology, Medical School Hannover, Germany
World J Urol 19:443-52. 2002..BOO is found in 95.5% of men with a detrusor wall thickness greater than or equal to 2 mm. Measuring the thickness of the detrusor wall can be used as a screening test to detect BOO...
International Consultation on Incontinence-Research Society (ICI-RS) report on non-invasive urodynamics: the need of standardization of ultrasound bladder and detrusor wall thickness measurements to quantify bladder wall hypertrophyMatthias Oelke
Department of Urology, Hannover Medical School, Hannover, Germany
Neurourol Urodyn 29:634-9. 2010..The ICI-RS intends to found a standardization committee that will initiate and judge studies on ultrasonic bladder wall measurements to clarify the most suitable, most accurate, and least invasive measurement technique...
Immunohistochemical distribution of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human vagina: a potential forensic value?Knut Albrecht
Hannover Medical School, Deparment of Legal Medicine, Carl Neuberg Strasse 1, 30625 Hannover, Germany
J Forensic Leg Med 14:270-4. 2007....
Insertion sheaths prevent breakage of flexible ureteroscopes due to laser fiber passage: a video-endoluminal study of the working channelThomas R W Herrmann
Department of Urology and Uro Oncology, Hannover Medical School MHH, Hannover, Germany
J Endourol 24:1747-51. 2010....
Thulium laser enucleation of the prostate (ThuLEP): transurethral anatomical prostatectomy with laser support. Introduction of a novel technique for the treatment of benign prostatic obstructionThomas R W Herrmann
Department of Urology and Urological Oncology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
World J Urol 28:45-51. 2010....
Laser treatments of the prostate vs TURP/ open prostatectomy: systematic review of urodynamic dataT R W Herrmann
Department of Urology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
Minerva Urol Nefrol 61:309-24. 2009..Therefore, new laser techniques (such as thulium laser vapoenucleation of the prostate) should be investigated by urodynamic studies in the future...
Historical aspects of the treatment of urinary incontinenceD Schultheiss
Department of Urology, Hannover Medical School, Hannover, Germany
Eur Urol 38:352-62. 2000....
[Expression of corticotropin releasing factor receptor 2 (CRFR2) in the human prostate. A new potential target for medical therapy of benign prostatic hyperplasia]H Tezval
Klinik für Urologie und Uroonkologie, Medizinische Hochschule, Hannover, Deutschland
Urologe A 47:1079-80, 1082-4. 2008..However, CRFR2 expression in human benign prostatic tissue remains unknown. Our study therefore aimed to investigate CRFR2 expression in prostatic tissue...
[The relevance of urinary bladder filling in suprapubic bladder catheterization]K Albrecht
Institut fur Rechtsmedizin, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
Urologe A 43:178-84. 2004..In all cases with a bladder filling volume > or =300 ml, the distances were > or =5 cm. Based on our measurements, we recommend a preoperative bladder filling of > or =300 ml for an uncomplicated insertion of a suprapubic catheter...
Age-stratified normal values for prostate volume, PSA, maximum urinary flow rate, IPSS, and other LUTS/BPH indicators in the German male community-dwelling population aged 50 years or olderRichard Berges
Department of Urology, PAN Klinik, Zeppelinstr 1, 50667, Cologne, Germany
World J Urol 29:171-8. 2011..These community-derived values of healthy older men are necessary to correctly judge patients with lower urinary tract symptoms due to benign prostatic hyperplasia (LUTS/BPH)...
Does diabetes mellitus-induced bladder remodeling affect lower urinary tract function? ICI-RS 2011Ruth Kirschner-Hermanns
Department of Urology, Continence Clinic, Aachen University Clinic RWTH, Aachen, Germany
Neurourol Urodyn 31:359-64. 2012..The purpose of this ICS-RS report is to highlight clinical and basic research data to outline directions for further research and possible treatment approaches...
Cyclic adenosine monophosphate and cyclic guanosine monophosphate-phosphodiesterase isoenzymes in human vagina: relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nervesStefan Uckert
Department of Urology, Hannover Medical School, Hannover, Germany
Urology 65:604-10. 2005..Nitric oxide and VIP, mediating biologic signals through cGMP and cAMP, have been assumed to be involved in the control of vaginal smooth muscle...
Phosphodiesterase inhibitors in clinical urologyStefan Uckert
Department of Urology and Urological Oncology, Division of Surgery, Hannover Medical School, Hannover, Germany
Expert Rev Clin Pharmacol 6:323-32. 2013....
Diagnosis and medical treatment of lower urinary tract symptoms in adult men: applying specialist guidelines in clinical practiceMatthias Oelke
Hannover Medical School, Hannover, Germany
BJU Int 110:710-8. 2012..This paper will improve the consistency of treatment approaches for adult males with LUTS by providing a clear, concise summary of existing treatment guidelines that can be easily adopted by urologists and primary care specialists...
Phosphodiesterase (PDE) inhibitors in the treatment of lower urinary tract dysfunctionStefan Uckert
Hannover Medical School, Division of Surgery, Department of Urology and Urological Oncology, Hannover, Germany
Br J Clin Pharmacol 72:197-204. 2011..The strategy of modulating the activity of PDE isoenzymes might represent a novel approach in patients with lower urinary tract dysfunction (LUTD)...
Immunohistochemical description of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human labia minoraStefan Uckert
Hannover Medical School Department of Urology, Hannover, Germany
J Sex Med 4:602-8. 2007..Some findings indicated that there might be a significance of cyclic nucleotide-mediated pathways in the control of the normal function of female genital tissues...
In vitro functional responses of isolated human vaginal tissue to selective phosphodiesterase inhibitorsStefan Uckert
Department of Urology, Hannover Medical School, Carl Neuberg Str 1, 30625, Hannover, Germany
World J Urol 23:398-404. 2005..This might be of significance with regard to the pharmacological treatment of disorders connected with female sexual arousal and the ability to achieve orgasm...
Expression of messenger ribonucleic acid encoding for phosphodiesterase isoenzymes in human female genital tissuesStefan Uckert
Hannover Medical School Department of Urology, Hannover, Germany, and IPF Pharmaceuticals GmbH Urological Research Unit, Hannover, Germany
J Sex Med 4:1604-9. 2007..The elevated expression of PDE5 in the human penile erectile tissue is considered the reason for the high clinical efficacy of PDE5 inhibitors in the pharmacotherapy of male erectile dysfunction...
Immunohistochemical distribution of cAMP- and cGMP-phosphodiesterase (PDE) isoenzymes in the human prostateStefan Uckert
Hannover Medical School, Department of Urology, Hannover, Germany
Eur Urol 49:740-5. 2006..The aim of the present study was to evaluate by means of immunohistochemistry the expression and distribution of some cAMP- and cGMP-PDE isoenzymes in the prostate...
Bladder wall thickness in healthy school-aged childrenMatthias Oelke
Urology 72:233-4; author reply 234-5. 2008
Clinical relevance of urodynamic investigation tests prior to surgical correction of genital prolapse: a literature reviewJan Paul W R Roovers
Department of Obstetrics and Gynaecology, Academic Medical Centre, University of Amsterdam, Room H4 205, P O Box 22700, 1105 DE, Amsterdam, The Netherlands
Int Urogynecol J Pelvic Floor Dysfunct 18:455-60. 2007..This review presents a literature overview of what has been proven about the diagnostic and therapeutic value of urodynamic investigations in patients undergoing prolapse surgery...
Diagnostic accuracy of noninvasive tests to evaluate bladder outlet obstruction in men: detrusor wall thickness, uroflowmetry, postvoid residual urine, and prostate volumeMatthias Oelke
Department of Urology, Academic Medical Center, University of Amsterdam, The Netherlands
Eur Urol 52:827-34. 2007....
Expression of cAMP and cGMP-phosphodiesterase isoenzymes 3, 4, and 5 in the human clitoris: immunohistochemical and molecular biology studyMatthias Oelke
Department of Urology, University of Amsterdam, Academic Medical Center, Amsterdam, The Netherlands
Urology 67:1111-6. 2006..We sought to elucidate the presence of the phosphodiesterase (PDE) isoenzymes 3, 4, and 5 in the human clitoris using immunohistochemical and molecular biology methods...
Ultrasound measurement of detrusor wall thickness in healthy adultsMatthias Oelke
Department of Urology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Neurourol Urodyn 25:308-17; discussion 318. 2006..The aim of this study was to determine DWT in healthy adults and to investigate if bladder filling, gender, age, or body-mass index (BMI) influences DWT...
Drug-induced urinary incontinencePeter Tsakiris
Department of Urology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Drugs Aging 25:541-9. 2008..However, other drug classes are not innocent in terms of causing urinary incontinence and physicians are well advised to closely monitor patients for the occurrence of incontinence after new prescriptions and/or major dosage changes...
