Research Topics
| H NaveSummaryAffiliation: Hannover Medical School Country: Germany Publications
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Detail Information
Publications
Reduced tissue immigration of monocytes by neuropeptide Y during endotoxemia is associated with Y2 receptor activationHeike Nave
Department of Functional and Applied Anatomy, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
J Neuroimmunol 155:1-12. 2004..Thus, NPY treatment has profound receptor-specific effects on the migration and adhesion of leukocytes under endotoxemic conditions...
Resistance of Janus kinase-2 dependent leptin signaling in natural killer (NK) cells: a novel mechanism of NK cell dysfunction in diet-induced obesityHeike Nave
Institute for Functional and Applied Anatomy, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
Endocrinology 149:3370-8. 2008..The differential role of leptin has important implications for the influence of body weight in the response to systemic inflammations and in the immunological defense of cancer...- Changes in cerebral endothelial barrier antigen, without alteration of permeability for intravenously injected leptin in diet-induced obesity in ratsHeike Nave
Department of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany
Exp Toxicol Pathol 55:45-9. 2003..Further functional and morphological studies are necessary to evaluate the specific role of other organs and distinct forms of leptin (free and protein-bound) in the pathogenesis of diet-induced obesity... - Morphology and immunology of the human palatine tonsilH Nave
Department of Functional and Applied Anatomy, Hannover Medical School, Germany
Anat Embryol (Berl) 204:367-73. 2001..This is of increasing importance since it has been discovered in the last few years that the palatine tonsils are reservoir and replication sites of HIV... - Brain NPY Y1 receptors rapidly mediate the behavioral response to novelty and a compartment-specific modulation of granulocyte function in blood and spleenS von Horsten
Department of Functional and Applied Anatomy, Medical School of Hannover, Hannover, Germany
Brain Res 806:282-6. 1998..Furthermore, the immunological effects of NPY demonstrate compartment specificity... - Diet-induced obesity alters behavior as well as serum levels of corticosterone in F344 ratsT Buchenauer
Institute for Functional and Applied Anatomy, Hannover Medical School, 30625 Hannover, Germany
Physiol Behav 98:563-9. 2009..5ng/ml; p<0.01). We conclude that obese rats differ in various aspects from their lean littermates. The altered behavioral characteristics displayed by DIO F344 rats have to be considered in further experiments involving DIO rodents... - Stereological quantification of carboxyfluorescein-labeled rat lung metastasis: a new method for the assessment of natural killer cell activity and tumor adhesion in vivo and in situS von Horsten
Medical School of Hannover, OE 4120, Department of Functional and Applied Anatomy, Carl Neuberg Strasse 1, 30625, Hannover, Germany
J Immunol Methods 239:25-34. 2000..This new approach facilitates the monitoring of effector-to-target interactions and the quantification of immune cell function or tumor adhesion in vivo and in situ... - Ghrelin treatment increases receptor-bound leptin in healthy and endotoxemic obese Lewis ratsC Macke
Institute for Functional and Applied Anatomy, Hannover Medical School, Hannover 30625, Germany
Exp Clin Endocrinol Diabetes 117:473-9. 2009..Both fl and bl levels remained unaffected in lean rats. The findings suggest that an increased body weight of the treated animals is associated with altered hormone levels after therapeutic interventions with ghrelin... - Differential effects of neuropeptide Y (NPY) on leukocyte subsets in the blood: mobilization of B-1-like B-lymphocytes and activated monocytesS Bedoui
Department of Functional and Applied Anatomy, OE 4120, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany
J Neuroimmunol 117:125-32. 2001..These data suggest a role for the sympathetic neurotransmitter NPY in neuroimmune alterations in vivo... - Applied anatomy of the superior vena cava-the carina as a landmark to guide central venous catheter placementK Albrecht
Institute of Legal Medicine, Medical School Hannover, D 30623 Hannover, Germany
Br J Anaesth 92:75-7. 2004..The carina is an alternative radiographic marker for correct CVC placement, suggested on the basis of studies of embalmed cadavers... - Modulation of innate immune functions by intracerebroventricularly applied neuropeptide Y: dose and time dependent effectsS von Horsten
Division of Functional and Applied Anatomy, Medical School of Hannover, Germany
Life Sci 63:909-22. 1998..Cell mobilization from the vascular marginal pool is likely to be an underlying mechanism for the initial immunosuppression... - Secretion of free and protein-bound leptin from subcutaneous adipose tissue of lean and obese womenG Brabant
Abteilungen Klinische Endokrinologie, Medizinische Hochschule Hannover, 30623 Hannover, Germany
J Clin Endocrinol Metab 87:3966-70. 2002..005 for FL; P < 0.02 for BL, and P < 0.01 for LR). In summary, fat cells are capable of releasing not only FL, but also BL and LR... - In vivo and in vitro evidence for a hepatic modulation of the leptin signal in ratsG Brabant
Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
Eur J Clin Invest 34:831-7. 2004..They are released from adipose tissue but previous data suggest an additional formation outside the fat compartment. Here we tested the contribution of the liver in binding and modulating leptin in the circulation... - Evaluation of the medical curriculum: why, when, by whom and for whom should questionnaires be usedR Pabst
Functional and Applied Anatomy, Medical School of Hannover, Hannover, Germany
Eur J Morphol 39:237-9. 2001..Anatomists should utilize these evaluations to improve teaching... - Prospective analysis of the long-term effect of teaching breast self-examination and breast awarenessL Funke
Department of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany
Eur J Cancer Care (Engl) 17:477-82. 2008..The data demonstrate that the seminars in BSE had profound effects on the compliance of women in carrying out BSE regularly and correctly, without influence of age or education... - Seminar in breast self-examination for female medical students integrated into a human gross anatomy courseV Fischer
Office for Student Affairs, Hannover Medical School, Hannover, Germany
Clin Anat 16:160-4. 2003..Because of the prevalence of breast cancer, it is recommended that such a seminar become an integral part of the preclinical curriculum for all female medical students... - Surgery as primary treatment in patients with liver metastases from carcinoid tumors: a retrospective, unicentric study over 13 yearsH Nave
Clinic of Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany
Surgery 129:170-5. 2001..CONCLUSIONS: Surgery for metastatic carcinoid tumors may be curative or palliative, with a potential for cure in some cases and prolongation of survival and amelioration of symptoms in the majority of patients... - Hepatic leptin signaling in obesityGeorg Brabant
Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
FASEB J 19:1048-50. 2005..Thus, the liver seems to play a major role in the modulation of the leptin signal and insulin resistance in obesity... - The carina as a landmark for central venous catheter placement in small childrenKnut Albrecht
Institute of Legal Medicine, Hannover Medical School, Carl Neuberg Str 1, 30625, Hannover, Germany
Eur J Pediatr 165:264-6. 2006.... - Laparoscopy vs minilaparotomy and full laparotomy preserves circulatory but not peritoneal and pulmonary immune responsesNatalie K Jesch
Department of Pediatric Surgery, Hanover Medical School, 30625 Hanover, Germany
J Pediatr Surg 41:1085-92. 2006..Our results may lead to further preference for the laparoscopic approach over minilaparotomy and full laparotomy... - Obesity influences the food consumption and cytokine pattern in ghrelin-treated endotoxemic ratsNils K Prenzler
Department of Functional and Applied Anatomy, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
Life Sci 81:80-7. 2007..These data further document the necessity to differentiate between normal weight and obese subjects in the attempt to establish ghrelin as a therapeutic target in endotoxemia... 
Neuropeptide Y stabilizes body temperature and prevents hypotension in endotoxaemic ratsMelanie Felies
Department of Functional and Applied Anatomy, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany
J Physiol 561:245-52. 2004..These telemetrically obtained findings clearly demonstrate that pretreatment with NPY positively influences two life-threatening symptoms in endotoxaemia and might be a future option for a successful clinical treatment regimen...- NPY modulates epinephrine-induced leukocytosis via Y-1 and Y-5 receptor activation in vivo: sympathetic co-transmission during leukocyte mobilizationSammy Bedoui
Department of Functional and Applied Anatomy, Hannover Medical School, 30625 Hanover, Germany
J Neuroimmunol 132:25-33. 2002..Thus, via a specific Y-1R/Y-5R interplay, NPY acts as a neuroimmune co-transmitter in vivo... - Perioperative normothermia depends on intraoperative warming procedure, extent of the surgical intervention and age of the experimental animalMelanie Felies
Department of Functional and Applied Anatomy, Hannover Medical School, Carl-Neuberg-Str.1, 30625 Hannover, Germany
Life Sci 77:3133-40. 2005....