B Mohammadi

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. ncbi Interaction of high concentrations of riluzole with recombinant skeletal muscle sodium channels and adult-type nicotinic receptor channels
    Bahram Mohammadi
    Department of Neurology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Muscle Nerve 26:539-45. 2002
  2. ncbi Interaction of topiramate with glycine receptor channels
    Bahram Mohammadi
    Department of Neurology, Medical University Hannover, Carl Neuberg Str 1, 30625 Hannover, Germany
    Pharmacol Res 51:587-92. 2005
  3. ncbi Correlation between distal motor latency and compound muscle action potential in amyotrophic lateral sclerosis
    Bahram Mohammadi
    Department of Neurology and Clinical Neurophysiology, Medical School of Hannover, Hannover, Germany
    Neurol Res 29:425-8. 2007
  4. doi A long-term follow-up of botulinum toxin A in cervical dystonia
    B Mohammadi
    Department of Neurology and Clinical Neurophysiology, Hannover Medical School, Hannover, Germany
    Neurol Res 31:463-6. 2009
  5. pmc Prognostic value of cortically induced motor evoked activity by TMS in chronic stroke: caveats from a revealing single clinical case
    Julià L Amengual
    Neurodynamic Laboratory, Departament of Psychiatry and Clinical Psychobiology Universitat de Barcelona, 08035, Barcelona, Spain
    BMC Neurol 12:35. 2012
  6. doi Long-term treatment of spasticity with botulinum toxin type A: an analysis of 1221 treatments in 137 patients
    B Mohammadi
    Department of Neurology and Clinical Neurophysiology, Medical School Hannover, Hannover, Germany
    Neurol Res 32:309-13. 2010
  7. doi Experience with long-term treatment with albumin-supplemented botulinum toxin type A
    Bahram Mohammadi
    Department of Neurology and Clinical Neurophysiology, Medical School Hannover, Hannover, Germany
    J Neural Transm 116:437-41. 2009
  8. doi Role of endotoxin in the pathogenesis of critical illness polyneuropathy
    B Mohammadi
    Department of Neurology, Medical School Hannover, Carl Neuberg Strasse 1, Hannover, Germany
    J Neurol 255:265-72. 2008
  9. ncbi Selective and nonselective benzodiazepine agonists have different effects on motor cortex excitability
    Bahram Mohammadi
    Department of Neurology and Clinical Neurophysiology, Medical School of Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Muscle Nerve 33:778-84. 2006
  10. ncbi Two different modes of action of pentobarbital at glycine receptor channels
    Bahram Mohammadi
    Department of Neurology, Medical University Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Eur J Pharmacol 489:151-6. 2004

Collaborators

Detail Information

Publications29

  1. ncbi Interaction of high concentrations of riluzole with recombinant skeletal muscle sodium channels and adult-type nicotinic receptor channels
    Bahram Mohammadi
    Department of Neurology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Muscle Nerve 26:539-45. 2002
    ....
  2. ncbi Interaction of topiramate with glycine receptor channels
    Bahram Mohammadi
    Department of Neurology, Medical University Hannover, Carl Neuberg Str 1, 30625 Hannover, Germany
    Pharmacol Res 51:587-92. 2005
    ..However, in presence of 1 mM glycine + 1 mM TPM, the desensitization got faster and the peak current amplitude decreased. After the end of glycine + TPM pulses, off-currents occurred, suggestive for a specific channel block mechanism...
  3. ncbi Correlation between distal motor latency and compound muscle action potential in amyotrophic lateral sclerosis
    Bahram Mohammadi
    Department of Neurology and Clinical Neurophysiology, Medical School of Hannover, Hannover, Germany
    Neurol Res 29:425-8. 2007
    ..The measurement of motor conduction of peripheral nerves is of major importance to recognize other possible causes of progressive muscle wasting. However, there are also pathologic changes in nerve conduction studies in ALS patients...
  4. doi A long-term follow-up of botulinum toxin A in cervical dystonia
    B Mohammadi
    Department of Neurology and Clinical Neurophysiology, Hannover Medical School, Hannover, Germany
    Neurol Res 31:463-6. 2009
    ..Cervical dystonia (CD) is the most common form of adult-onset focal dystonia, and botulinum toxin A (BoNT-A) has become the first-line treatment for this condition...
  5. pmc Prognostic value of cortically induced motor evoked activity by TMS in chronic stroke: caveats from a revealing single clinical case
    Julià L Amengual
    Neurodynamic Laboratory, Departament of Psychiatry and Clinical Psychobiology Universitat de Barcelona, 08035, Barcelona, Spain
    BMC Neurol 12:35. 2012
    ....
  6. doi Long-term treatment of spasticity with botulinum toxin type A: an analysis of 1221 treatments in 137 patients
    B Mohammadi
    Department of Neurology and Clinical Neurophysiology, Medical School Hannover, Hannover, Germany
    Neurol Res 32:309-13. 2010
    ..Spasticity is a complex disorder that causes significant disability in affected patients. We here present long-term results of botulinum toxin type A (BoNT-A) treatment in spasticity of various etiologies in the upper and lower limbs...
  7. doi Experience with long-term treatment with albumin-supplemented botulinum toxin type A
    Bahram Mohammadi
    Department of Neurology and Clinical Neurophysiology, Medical School Hannover, Hannover, Germany
    J Neural Transm 116:437-41. 2009
    ..We conclude that long-term treatment with ASBTA is effective, safe and help to reduce costs...
  8. doi Role of endotoxin in the pathogenesis of critical illness polyneuropathy
    B Mohammadi
    Department of Neurology, Medical School Hannover, Carl Neuberg Strasse 1, Hannover, Germany
    J Neurol 255:265-72. 2008
    ..g. by activation of inflammatory cascades (IL2-R). Endotoxin appears to be an essential factor in the pathogenesis of CIP in sepsis, and therapeutic options neutralizing endotoxin may prevent development of CIP...
  9. ncbi Selective and nonselective benzodiazepine agonists have different effects on motor cortex excitability
    Bahram Mohammadi
    Department of Neurology and Clinical Neurophysiology, Medical School of Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Muscle Nerve 33:778-84. 2006
    ..This selective modulation of the CSP and the LICI points to a specific role of BZ1 receptors in the control of inhibitory neuronal loops within the primary motor cortex...
  10. ncbi Two different modes of action of pentobarbital at glycine receptor channels
    Bahram Mohammadi
    Department of Neurology, Medical University Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Eur J Pharmacol 489:151-6. 2004
    ..After the end of glycine+pentobarbital pulses, off-currents occurred suggestive for a channel block mechanism. Pentobarbital had no agonistic effects at glycine receptor channels...
  11. pmc Mechanisms of cold sensitivity of paramyotonia congenita mutation R1448H and overlap syndrome mutation M1360V
    Bahram Mohammadi
    Department of Neurology, Medical School Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    J Physiol 547:691-8. 2003
    ..The window current by mutation R1448H was increased at lower temperatures. The results of this study may explain the stronger cold-induced clinical symptoms resulting from the R1448H mutation in contrast to the M1360V mutation...
  12. ncbi The anesthetic propofol modulates gating in paramyotonia congenita mutant muscle sodium channels
    G Haeseler
    Department of Anesthesiology, OE8050, Hannover Medical School, D 30623 Hannover, Germany
    Muscle Nerve 24:736-43. 2001
    ..Our in vitro results show that inactivation-deficient sodium channels are specifically targeted and blocked by propofol. This might reduce enhanced muscle excitability experienced by affected patients in vivo...
  13. ncbi Interaction of the neuroprotective drug riluzole with GABA(A) and glycine receptor channels
    B Mohammadi
    Neurological Department, Medical School Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Germany
    Eur J Pharmacol 415:135-40. 2001
    ..The data of the study demonstrate for the first time interaction of GABAergic and glycinergic currents with riluzole under physiological conditions...
  14. ncbi Kinetic analysis of recombinant mammalian alpha(1) and alpha(1)beta glycine receptor channels
    B Mohammadi
    Department of Neurology, Medical SchoolUniversity Hannover, Carl Neuberg Str 1, 30625, Hannover, Germany
    Eur Biophys J 32:529-36. 2003
    ..It was best fitted with two time constants for both alpha(1) and alpha(1)beta GlyR channels, and increased significantly with increasing pulse duration...
  15. ncbi Deactivation and desensitization of mouse embryonic- and adult-type nicotinic receptor channel currents
    K Jahn
    Department of Neurology, Ludwig Maximilians University of Munich, Klinikum Grosshadern, Marchioninistrasse 15, 81377, Munich, Germany
    Neurosci Lett 307:89-92. 2001
    ..85+/-1.2 ms, gamma: 3.85+/-2.1 ms). It is assumed that differences in deactivation are of functional relevance at the muscle endplate...
  16. ncbi Structural requirements of phenol derivatives for direct activation of chloride currents via GABA(A) receptors
    B Mohammadi
    Department of Neurology and Neurophysiology, Hannover Medical School, D-30623, Hannover, Germany
    Eur J Pharmacol 421:85-91. 2001
    ..These results show that the position of the aliphatic substituents with respect to the phenolic hydroxyl group is the crucial structural feature for direct GABA(A) activation by phenol derivatives...
  17. ncbi Different effects of mexiletine on two mutant sodium channels causing paramyotonia congenita and hyperkalemic periodic paralysis
    K Weckbecker
    Department of Neurology, Medizinische Hochschule, Hannover, Germany
    Neuromuscul Disord 10:31-9. 2000
    ..The enhanced use-dependent block as seen with R1448H may explain the extraordinary therapeutic efficacy of mexiletine in most patients with paramyotonia congenita...
  18. ncbi IgG from patients with Guillain-Barré syndrome interact with nicotinic acetylcholine receptor channels
    K Krampfl
    Department of Neurology, Medical School Hannover, Germany
    Muscle Nerve 27:435-41. 2003
    ..The observed postsynaptic block effect fulfills the criteria of a channel-blocking IgG antibody similar to those seen in autoimmune myasthenia and may contribute to muscle weakness during the acute phase of GBS...
  19. ncbi Mirror movements and ipsilateral motor evoked potentials in ALS
    Klaus Krampfl
    Department of Neurology, Medical University of Hannover, Hannover, Germany
    Amyotroph Lateral Scler Other Motor Neuron Disord 5:154-63. 2004
    ..Central motor conduction times were prolonged in 15 ALS patients (27%). It is concluded that MMs, especially if studied by EMG and TMS (IMEPs) can essentially improve detection of UMN involvement, especially in early stages of ALS...
  20. doi Audiovisual integration of speech is disturbed in schizophrenia: an fMRI study
    G R Szycik
    Clinic for Psychiatry, Social Psychiatry and Psychotherapy, Medical School Hannover, Germany
    Schizophr Res 110:111-8. 2009
    ..Furthermore the results can be also seen as a reflection of reduced lateralization of language functions to the left hemisphere in schizophrenia...
  21. ncbi Liver transplantation improves hepatic myelopathy: evidence by three cases
    Karin Weissenborn
    Department of Neurology, Medizinische Hochschule Hannover, Germany
    Gastroenterology 124:346-51. 2003
    ..The aim of this study was to find out whether orthotopic liver transplantation (OLT) may improve hepatic myelopathy...
  22. ncbi Amyotrophic lateral sclerosis (ALS) and mirror movements in a patient with polymicrogyria
    Klaus Krampfl
    Department of Neurology, Medizinische Hochschule, Hannover, Germany
    Amyotroph Lateral Scler Other Motor Neuron Disord 4:266-9. 2003
    ..The corpus callosum was completely developed and of normal size. We hypothesize an enrolment of the dysplastic right frontal lobe pathophysiology of the observed mirror movements...
  23. doi Hemifacial spasm and reinnervation synkinesias: long-term treatment with either Botox or Dysport
    Katja Kollewe
    Movement Disorders Section, Department of Neurology, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    J Neural Transm 117:759-63. 2010
    ..56 there were no differences between both drugs with respect to therapeutic efficacy and adverse effects thus confirming the hypothesis that there may not be intrinsic differences between both products...
  24. doi Patterns of cortical activity differ in ALS patients with limb and/or bulbar involvement depending on motor tasks
    Katja Kollewe
    Department of Neurology and Clinical Neurophysiology, Medical School of Hannover, Hannover, Germany
    J Neurol 258:804-10. 2011
    ..Thus, two different patterns of cortical activation changes suggesting fundamental differences in the neurodegenerative process and subsequent reorganisation processes exist for limb and bulbar movements...
  25. ncbi Preferred mexiletine block of human sodium channels with IVS4 mutations and its pH-dependence
    Bahram Mohammadi
    Department of Neurology, Medical School Hannover, Hannover, Germany
    Pharmacogenet Genomics 15:235-44. 2005
    ....
  26. ncbi 2,6 di-tert-butylphenol, a nonanesthetic propofol analog, modulates alpha1beta glycine receptor function in a manner distinct from propofol
    Jorg Ahrens
    Department of Anaesthesiology, Hannover Medical School, Hannover, Germany
    Anesth Analg 99:91-6. 2004
    ..Propofol and its nonanesthetic structural analog do not differ in their ability to coactivate the glycine receptor but differ in their ability to directly activate the receptor in the absence of the natural agonist...
  27. doi ALSFRS-R score and its ratio: a useful predictor for ALS-progression
    Katja Kollewe
    Department of Neurology and Clinical Neurophysiology, Medical School of Hannover, Carl Neuberg Str 1, 30625 Hannover, Germany
    J Neurol Sci 275:69-73. 2008
    ..We conclude that the ratio of ALSFRS-R score within 100 days is a useful parameter for clinical trials and daily clinical work in a tertiary ALS-clinic...
  28. ncbi Reduced delayed rectifier K+ current, altered electrophysiology, and increased ventricular vulnerability in MLP-deficient mice
    Ajmal Gardiwal
    Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany
    J Card Fail 13:687-93. 2007
    ..In humans, MLP-expression is downregulated both in ischemic and dilative cardiomyopathy. In this study, we investigated the effects of MLP on the electrophysiologic phenotype in vivo and on outward potassium currents...
  29. doi Movement initiation and inhibition are impaired in amyotrophic lateral sclerosis
    Johannes Thorns
    Department of Neurology, University of Lubeck, Germany
    Exp Neurol 224:389-94. 2010
    ..In conclusion, ALS patients showed deficits in both, movement initiation and inhibition, with the latter associated with prefrontal dysfunction...