Research Topics
Species | Kirsten R Müller-VahlSummaryAffiliation: Hannover Medical School Country: Germany Publications
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Publications
Tourette's syndromeKirsten R Müller-Vahl
Clinic of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, D 30625, Hannover, Germany
Curr Top Behav Neurosci 1:397-410. 2009....
Prefrontal and anterior cingulate cortex abnormalities in Tourette Syndrome: evidence from voxel-based morphometry and magnetization transfer imagingKirsten R Müller-Vahl
Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany
BMC Neurosci 10:47. 2009....
Cannabis and schizophrenia: towards a cannabinoid hypothesis of schizophreniaKirsten R Müller-Vahl
Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
Expert Rev Neurother 8:1037-48. 2008..Thus, agents that interact with the cannabinoid receptor system, such as the nonpsychoactive cannabidiol, might be beneficial in the treatment of psychosis...
The influence of different food and drink on tics in Tourette syndromeKirsten R Müller-Vahl
Clinic of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany
Acta Paediatr 97:442-6. 2008..Because standard medication often remains unsatisfactory, many patients seek alternative medicine. The aim of this study was to increase experience about the influence of food and drinks in TS...
[The benzamides tiapride, sulpiride, and amisulpride in treatment for Tourette's syndrome]K R Muller-Vahl
Abteilung für Klinische Psychiatrie und Psychotherapie, Medizinische Hochschule Hannover, Carl Neuberg Stasse 1, 30625 Hannover
Nervenarzt 78:264, 266-8, 270-1. 2007..Today it is unknown whether new atypical neuroleptic drugs including the benzamide amisulpride are more effective than the older benzamides tiapride and sulpiride...
Serotonin transporter binding in Tourette SyndromeKirsten R Müller-Vahl
Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Carl Neuberg Str 1, D 30625 Hannover, Germany
Neurosci Lett 385:120-5. 2005..038). Our data are in agreement with previous results suggesting an impairment of the serotonergic system in TS. It can be speculated that the reduction in SERT binding capacity is associated with the degree of comorbid OCB...
European clinical guidelines for Tourette syndrome and other tic disorders. Part IV: deep brain stimulationKirsten R Müller-Vahl
Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
Eur Child Adolesc Psychiatry 20:209-17. 2011..It is highly recommended to perform DBS in the context of controlled trials...
Cannabinoids reduce symptoms of Tourette's syndromeKirsten R Müller-Vahl
Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Carl Neuberg Str 1, D 30625 Hannover, Germany
Expert Opin Pharmacother 4:1717-25. 2003..At present, it remains unclear whether herbal cannabis, different natural or synthetic cannabinoid CB1-receptor agonists or agents that interfere with the inactivation of endocannabinoids, may have the best adverse effect profile in TS...
Delta 9-tetrahydrocannabinol (THC) is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trialKirsten R Müller-Vahl
Department of Clinical Psychiatry and Psychotherapy, Medical School of Hannover, Hannover, Germany
J Clin Psychiatry 64:459-65. 2003..This study was performed to investigate for the first time under controlled conditions, over a longer-term treatment period, whether THC is effective and safe in reducing tics in TS...
The treatment of Tourette's syndrome: current opinionsKirsten R Müller-Vahl
Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Carl Neuberg Str 1, D 30625 Hannover, Germany
Expert Opin Pharmacother 3:899-914. 2002..Recent studies have provided increasing evidence that stimulants do not cause a significant increase in tics in the majority of patients...
Treatment of Tourette's syndrome with Delta 9-tetrahydrocannabinol (THC): a randomized crossover trialK R Muller-Vahl
Department of Clinical Psychiatry and Psychotherapy, Hanover Medical School, Germany
Pharmacopsychiatry 35:57-61. 2002..It can be speculated that clinical effects may be caused by 11-OH-THC. A more long-term study is required to confirm these results...
Cannabis in movement disordersK R Muller-Vahl
Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Germany
Forsch Komplementarmed 6:23-7. 1999..It can be speculated that cannabinoid antagonists might be useful in the treatment of chorea in Huntington s disease and hypokinetic parkinsonian syndromes...
Dopamine transporter binding in Gilles de la Tourette syndromeK R Muller-Vahl
Department of Clinical Psychiatry and Psychotherapy, Medical School of Hannover, Germany
J Neurol 247:514-20. 2000..Our results demonstrate that an increase in dopamine transporter capacity is a possible but not a necessary alteration, and which appears more likely when self-injurious behavior and lack of impulse control are associated...
Influence of treatment of Tourette syndrome with delta9-tetrahydrocannabinol (delta9-THC) on neuropsychological performanceK R Muller-Vahl
Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Germany
Pharmacopsychiatry 34:19-24. 2001..We therefore suggest that further investigations should concentrate on the effects of a longer-term therapy of TS with delta9-THC...
Treatment of Tourette syndrome with delta-9-tetrahydrocannabinol (delta 9-THC): no influence on neuropsychological performanceKirsten R Müller-Vahl
Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Hannover, Germany
Neuropsychopharmacology 28:384-8. 2003..Larger and longer-duration controlled studies are recommended to provide more information on the adverse effect profile of THC in patients suffering from TS...
Lateral frontal cortex volume reduction in Tourette syndrome revealed by VBMMatthias Wittfoth
Department of Neurology, Hannover Medical School, Hannover, Germany
BMC Neurosci 13:17. 2012....
Chorea-acanthocytosis in monozygotic twins: clinical findings and neuropathological changes as detected by diffusion tensor imaging, FDG-PET and (123)I-beta-CIT-SPECTKirsten R Müller-Vahl
Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Carl Neuberg Str 1, D 30625, Hannover, Germany
J Neurol 254:1081-8. 2007..Our findings suggest that the main neuropathological process in ChAc is located in the striatum, involving microstructural alterations, and disturbance of metabolism and dopaminergic neurotransmission...
Electrophysiological measures and dual-task performance in Tourette syndrome indicate deficient divided attention mechanismsS Johannes
Department of Neuropsychology, Otto von Guericke Universitat, Magdeburg, Germany
Eur J Neurol 8:253-60. 2001..The allocation of attentional resources to competing tasks however, is altered. We speculate that this may be related to deficient inhibitory functions...
Altered inhibition of motor responses in Tourette Syndrome and Obsessive-Compulsive DisorderS Johannes
Department of Neuropsychology, Otto von Guericke Universitat, Magdeburg, Germany
Acta Neurol Scand 104:36-43. 2001..We hypothesized that both patient groups would display altered frontal inhibitory activity...
Effects of fentanyl and low doses of alcohol on neuropsychological performance in healthy subjectsU Schneider
Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Germany
Neuropsychobiology 39:38-43. 1999..After application of low doses of alcohol (BAC 0.03%) only visual reaction time was impaired in comparison to placebo...
Aripiprazole for the treatment of Tourette syndrome: a case series of 100 patientsClaudia Wenzel
Clinic of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany
J Clin Psychopharmacol 32:548-50. 2012..Because preliminary data obtained from uncontrolled studies suggest that aripiprazole may be effective in the treatment of tics, we performed a retrospective study with a large group of patients with Tourette syndrome...
Excessive action monitoring in Tourette syndromeSönke Johannes
Department of Neurology, Medical School of Hannover, Germany
J Neurol 249:961-6. 2002..A number of similarities to Obsessive-Compulsive Disorder are outlined and it is argued that the findings could be related to a hyperactive frontal-striatal-thalamic-frontal circuit...
Oligoclonal bands in cerebrospinal fluid in patients with Tourette's syndromeClaudia Wenzel
Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany
Mov Disord 26:343-6. 2011..Since none of them suffered from another disease known to be associated with OB, our results suggest an association with the pathogenesis of TS itself and point to an involvement of immunological mechanisms in TS pathology...
Tourette syndrome is not caused by mutations in the central cannabinoid receptor (CNR1) geneDorothea Gadzicki
Institute of Human Genetics, Hannover Medical School, Hannover, Germany
Am J Med Genet B Neuropsychiatr Genet 127:97-103. 2004..We conclude that genetic variations of the CNR1 gene are not a plausible explanation for the clinically observed relation between the cannabinoid system and TS...
