Kirsten R Müller-Vahl

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. doi request reprint Tourette's syndrome
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, D 30625, Hannover, Germany
    Curr Top Behav Neurosci 1:397-410. 2009
  2. ncbi request reprint Tourette patients' misbelief of a tic rebound is due to overall difficulties in reliable tic rating
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Germany Electronic address
    J Psychosom Res 76:472-6. 2014
  3. pmc Tics are caused by alterations in prefrontal areas, thalamus and putamen, while changes in the cingulate gyrus reflect secondary compensatory mechanisms
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Street 1, D 30625 Hannover, Germany
    BMC Neurosci 15:6. 2014
  4. doi request reprint Surgical treatment of Tourette syndrome
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Neurosci Biobehav Rev 37:1178-85. 2013
  5. doi request reprint Treatment of Tourette syndrome with cannabinoids
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Behav Neurol 27:119-24. 2013
  6. ncbi request reprint Serotonin transporter binding in Tourette Syndrome
    Kirsten R Müller-Vahl
    Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Neurosci Lett 385:120-5. 2005
  7. doi request reprint The influence of different food and drink on tics in Tourette syndrome
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany
    Acta Paediatr 97:442-6. 2008
  8. ncbi request reprint [The benzamides tiapride, sulpiride, and amisulpride in treatment for Tourette's syndrome]
    K R Muller-Vahl
    Abteilung für Klinische Psychiatrie und Psychotherapie, Medizinische Hochschule Hannover, Carl Neuberg Stasse 1, 30625 Hannover
    Nervenarzt 78:264, 266-8, 270-1. 2007
  9. doi request reprint Cannabis and schizophrenia: towards a cannabinoid hypothesis of schizophrenia
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Expert Rev Neurother 8:1037-48. 2008
  10. pmc Prefrontal and anterior cingulate cortex abnormalities in Tourette Syndrome: evidence from voxel-based morphometry and magnetization transfer imaging
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany
    BMC Neurosci 10:47. 2009

Detail Information

Publications29

  1. doi request reprint Tourette's syndrome
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, D 30625, Hannover, Germany
    Curr Top Behav Neurosci 1:397-410. 2009
    ....
  2. ncbi request reprint Tourette patients' misbelief of a tic rebound is due to overall difficulties in reliable tic rating
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Germany Electronic address
    J Psychosom Res 76:472-6. 2014
    ..We hypothesized that in adult patients there is a tic rebound after tic suppression...
  3. pmc Tics are caused by alterations in prefrontal areas, thalamus and putamen, while changes in the cingulate gyrus reflect secondary compensatory mechanisms
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Street 1, D 30625 Hannover, Germany
    BMC Neurosci 15:6. 2014
    ....
  4. doi request reprint Surgical treatment of Tourette syndrome
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Neurosci Biobehav Rev 37:1178-85. 2013
    ..However, most experts have no doubt that DBS is indeed effective in the treatment of tics. Future studies should aim to identify which target in which patient is optimal depending on the individual symptomatology...
  5. doi request reprint Treatment of Tourette syndrome with cannabinoids
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Behav Neurol 27:119-24. 2013
    ..In treatment resistant adult patients, therefore, treatment with THC should be taken into consideration...
  6. ncbi request reprint Serotonin transporter binding in Tourette Syndrome
    Kirsten R Müller-Vahl
    Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Neurosci Lett 385:120-5. 2005
    ..038). Our data are in agreement with previous results suggesting an impairment of the serotonergic system in TS. It can be speculated that the reduction in SERT binding capacity is associated with the degree of comorbid OCB...
  7. doi request reprint The influence of different food and drink on tics in Tourette syndrome
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany
    Acta Paediatr 97:442-6. 2008
    ..Because standard medication often remains unsatisfactory, many patients seek alternative medicine. The aim of this study was to increase experience about the influence of food and drinks in TS...
  8. ncbi request reprint [The benzamides tiapride, sulpiride, and amisulpride in treatment for Tourette's syndrome]
    K R Muller-Vahl
    Abteilung für Klinische Psychiatrie und Psychotherapie, Medizinische Hochschule Hannover, Carl Neuberg Stasse 1, 30625 Hannover
    Nervenarzt 78:264, 266-8, 270-1. 2007
    ..Today it is unknown whether new atypical neuroleptic drugs including the benzamide amisulpride are more effective than the older benzamides tiapride and sulpiride...
  9. doi request reprint Cannabis and schizophrenia: towards a cannabinoid hypothesis of schizophrenia
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Expert Rev Neurother 8:1037-48. 2008
    ..Thus, agents that interact with the cannabinoid receptor system, such as the nonpsychoactive cannabidiol, might be beneficial in the treatment of psychosis...
  10. pmc Prefrontal and anterior cingulate cortex abnormalities in Tourette Syndrome: evidence from voxel-based morphometry and magnetization transfer imaging
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany
    BMC Neurosci 10:47. 2009
    ....
  11. doi request reprint European clinical guidelines for Tourette syndrome and other tic disorders. Part IV: deep brain stimulation
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Eur Child Adolesc Psychiatry 20:209-17. 2011
    ..It is highly recommended to perform DBS in the context of controlled trials...
  12. ncbi request reprint Cannabinoids reduce symptoms of Tourette's syndrome
    Kirsten R Müller-Vahl
    Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Expert Opin Pharmacother 4:1717-25. 2003
    ..At present, it remains unclear whether herbal cannabis, different natural or synthetic cannabinoid CB1-receptor agonists or agents that interfere with the inactivation of endocannabinoids, may have the best adverse effect profile in TS...
  13. ncbi request reprint Delta 9-tetrahydrocannabinol (THC) is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trial
    Kirsten R Müller-Vahl
    Department of Clinical Psychiatry and Psychotherapy, Medical School of Hannover, Hannover, Germany
    J Clin Psychiatry 64:459-65. 2003
    ..This study was performed to investigate for the first time under controlled conditions, over a longer-term treatment period, whether THC is effective and safe in reducing tics in TS...
  14. ncbi request reprint Cannabis in movement disorders
    K R Muller-Vahl
    Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Germany
    Forsch Komplementarmed 6:23-7. 1999
    ..It can be speculated that cannabinoid antagonists might be useful in the treatment of chorea in Huntington s disease and hypokinetic parkinsonian syndromes...
  15. ncbi request reprint Dopamine transporter binding in Gilles de la Tourette syndrome
    K R Muller-Vahl
    Department of Clinical Psychiatry and Psychotherapy, Medical School of Hannover, Germany
    J Neurol 247:514-20. 2000
    ..Our results demonstrate that an increase in dopamine transporter capacity is a possible but not a necessary alteration, and which appears more likely when self-injurious behavior and lack of impulse control are associated...
  16. ncbi request reprint Influence of treatment of Tourette syndrome with delta9-tetrahydrocannabinol (delta9-THC) on neuropsychological performance
    K R Muller-Vahl
    Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Germany
    Pharmacopsychiatry 34:19-24. 2001
    ..We therefore suggest that further investigations should concentrate on the effects of a longer-term therapy of TS with delta9-THC...
  17. ncbi request reprint Treatment of Tourette's syndrome with Delta 9-tetrahydrocannabinol (THC): a randomized crossover trial
    K R Muller-Vahl
    Department of Clinical Psychiatry and Psychotherapy, Hanover Medical School, Germany
    Pharmacopsychiatry 35:57-61. 2002
    ..It can be speculated that clinical effects may be caused by 11-OH-THC. A more long-term study is required to confirm these results...
  18. ncbi request reprint The treatment of Tourette's syndrome: current opinions
    Kirsten R Müller-Vahl
    Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Expert Opin Pharmacother 3:899-914. 2002
    ..Recent studies have provided increasing evidence that stimulants do not cause a significant increase in tics in the majority of patients...
  19. ncbi request reprint Treatment of Tourette syndrome with delta-9-tetrahydrocannabinol (delta 9-THC): no influence on neuropsychological performance
    Kirsten R Müller-Vahl
    Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Hannover, Germany
    Neuropsychopharmacology 28:384-8. 2003
    ..Larger and longer-duration controlled studies are recommended to provide more information on the adverse effect profile of THC in patients suffering from TS...
  20. pmc Lateral frontal cortex volume reduction in Tourette syndrome revealed by VBM
    Matthias Wittfoth
    Department of Neurology, Hannover Medical School, Hannover, Germany
    BMC Neurosci 13:17. 2012
    ....
  21. doi request reprint Aripiprazole for the treatment of Tourette syndrome: a case series of 100 patients
    Claudia Wenzel
    Clinic of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany
    J Clin Psychopharmacol 32:548-50. 2012
    ..Because preliminary data obtained from uncontrolled studies suggest that aripiprazole may be effective in the treatment of tics, we performed a retrospective study with a large group of patients with Tourette syndrome...
  22. ncbi request reprint Effects of fentanyl and low doses of alcohol on neuropsychological performance in healthy subjects
    U Schneider
    Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Germany
    Neuropsychobiology 39:38-43. 1999
    ..After application of low doses of alcohol (BAC 0.03%) only visual reaction time was impaired in comparison to placebo...
  23. ncbi request reprint Altered inhibition of motor responses in Tourette Syndrome and Obsessive-Compulsive Disorder
    S Johannes
    Department of Neuropsychology, Otto von Guericke Universitat, Magdeburg, Germany
    Acta Neurol Scand 104:36-43. 2001
    ..We hypothesized that both patient groups would display altered frontal inhibitory activity...
  24. ncbi request reprint Electrophysiological measures and dual-task performance in Tourette syndrome indicate deficient divided attention mechanisms
    S Johannes
    Department of Neuropsychology, Otto von Guericke Universitat, Magdeburg, Germany
    Eur J Neurol 8:253-60. 2001
    ..The allocation of attentional resources to competing tasks however, is altered. We speculate that this may be related to deficient inhibitory functions...
  25. ncbi request reprint Chorea-acanthocytosis in monozygotic twins: clinical findings and neuropathological changes as detected by diffusion tensor imaging, FDG-PET and (123)I-beta-CIT-SPECT
    Kirsten R Müller-Vahl
    Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Carl Neuberg Str 1, D 30625, Hannover, Germany
    J Neurol 254:1081-8. 2007
    ..Our findings suggest that the main neuropathological process in ChAc is located in the striatum, involving microstructural alterations, and disturbance of metabolism and dopaminergic neurotransmission...
  26. ncbi request reprint Excessive action monitoring in Tourette syndrome
    Sönke Johannes
    Department of Neurology, Medical School of Hannover, Germany
    J Neurol 249:961-6. 2002
    ..A number of similarities to Obsessive-Compulsive Disorder are outlined and it is argued that the findings could be related to a hyperactive frontal-striatal-thalamic-frontal circuit...
  27. doi request reprint Oligoclonal bands in cerebrospinal fluid in patients with Tourette's syndrome
    Claudia Wenzel
    Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany
    Mov Disord 26:343-6. 2011
    ..Since none of them suffered from another disease known to be associated with OB, our results suggest an association with the pathogenesis of TS itself and point to an involvement of immunological mechanisms in TS pathology...
  28. pmc Can tics be performed convincingly by an actor?
    Kirsten R Müller-Vahl
    Clinic of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Carl Neuberg Strase 1, 30625 Hannover, Germany
    Behav Neurol 2014:893859. 2014
    ..Objective. The aim of this study was to investigate whether the performance of tics is convincing and whether this judgment depends on whether he/she suffers from tics or not...
  29. ncbi request reprint Tourette syndrome is not caused by mutations in the central cannabinoid receptor (CNR1) gene
    Dorothea Gadzicki
    Institute of Human Genetics, Hannover Medical School, Hannover, Germany
    Am J Med Genet B Neuropsychiatr Genet 127:97-103. 2004
    ..We conclude that genetic variations of the CNR1 gene are not a plausible explanation for the clinically observed relation between the cannabinoid system and TS...