Michael Mahler

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. ncbi Differential susceptibility of inbred mouse strains to Helicobacter pylori infection
    M Mahler
    Institute for Laboratory Animal Science and Central Animal Facility, Medical School Hannover, Germany
    Scand J Gastroenterol 37:267-78. 2002
  2. ncbi Genetics of colitis susceptibility in IL-10-deficient mice: backcross versus F2 results contrasted by principal component analysis
    Michael Mahler
    Institute for Laboratory Animal Science and Central Animal Facility, Medical School Hannover, Germany
    Genomics 80:274-82. 2002
  3. ncbi CpG motifs of bacterial DNA exert protective effects in mouse models of IBD by antigen-independent tolerance induction
    Andre Bleich
    Institute for Laboratory Animal Science and Central Animal Facility, Hannover Medical School, Hannover, Germany
    Gastroenterology 136:278-87. 2009
  4. ncbi Genetic and environmental context determines the course of colitis developing in IL-10-deficient mice
    Michael Mahler
    Institute for Laboratory Animal Science, Central Animal Facility, Medical School Hannover, Hannover, Germany
    Inflamm Bowel Dis 8:347-55. 2002
  5. ncbi Experimental Helicobacter pylori infection induces antral-predominant, chronic active gastritis in hispid cotton rats (Sigmodon hispidus)
    Michael Mahler
    Institute for Laboratory Animal Science and Central Animal Facility, Medical School Hannover, Hannover, Germany
    Helicobacter 10:332-44. 2005
  6. ncbi Refined histopathologic scoring system improves power to detect colitis QTL in mice
    Andre Bleich
    Institute for Laboratory Animal Science and Central Animal Facility, Hannover Medical School, 30625 Hannover, Germany
    Mamm Genome 15:865-71. 2004
  7. ncbi Hygienic monitoring of Mongolian gerbils: which mouse viruses should be included?
    Eva M Bleich
    Institute for Laboratory Animal Science and Central Animal Facility, Hannover Medical School, 30625 Hannover, Germany
    Lab Anim 46:173-5. 2012

Detail Information

Publications7

  1. ncbi Differential susceptibility of inbred mouse strains to Helicobacter pylori infection
    M Mahler
    Institute for Laboratory Animal Science and Central Animal Facility, Medical School Hannover, Germany
    Scand J Gastroenterol 37:267-78. 2002
    ..Host factors play an important part in the pathogenesis of Helicobacter pylori-associated disease. The aim of this study was to screen various inbred strains of mice for genetic differences in susceptibility to H. pylori infection...
  2. ncbi Genetics of colitis susceptibility in IL-10-deficient mice: backcross versus F2 results contrasted by principal component analysis
    Michael Mahler
    Institute for Laboratory Animal Science and Central Animal Facility, Medical School Hannover, Germany
    Genomics 80:274-82. 2002
    ..These findings show the complexity of inheritance underlying susceptibility to colitis and illustrate why detection of human inflammatory bowel disease loci has proven to be so difficult...
  3. ncbi CpG motifs of bacterial DNA exert protective effects in mouse models of IBD by antigen-independent tolerance induction
    Andre Bleich
    Institute for Laboratory Animal Science and Central Animal Facility, Hannover Medical School, Hannover, Germany
    Gastroenterology 136:278-87. 2009
    ..The aim of this study was to elucidate whether these CpG-dependent protective effects require presence of bacterial flora suggesting antigen-specific regulatory activity...
  4. ncbi Genetic and environmental context determines the course of colitis developing in IL-10-deficient mice
    Michael Mahler
    Institute for Laboratory Animal Science, Central Animal Facility, Medical School Hannover, Hannover, Germany
    Inflamm Bowel Dis 8:347-55. 2002
    ..These findings are discussed in the context of recent advances in understanding the complex genetic basis for IBD in humans...
  5. ncbi Experimental Helicobacter pylori infection induces antral-predominant, chronic active gastritis in hispid cotton rats (Sigmodon hispidus)
    Michael Mahler
    Institute for Laboratory Animal Science and Central Animal Facility, Medical School Hannover, Hannover, Germany
    Helicobacter 10:332-44. 2005
    ..The hispid cotton rat has proven to be an excellent animal model for a variety of human infectious disease agents. This study was performed to evaluate the use of the cotton rat as a model of Helicobacter pylori infection...
  6. ncbi Refined histopathologic scoring system improves power to detect colitis QTL in mice
    Andre Bleich
    Institute for Laboratory Animal Science and Central Animal Facility, Hannover Medical School, 30625 Hannover, Germany
    Mamm Genome 15:865-71. 2004
    ....
  7. ncbi Hygienic monitoring of Mongolian gerbils: which mouse viruses should be included?
    Eva M Bleich
    Institute for Laboratory Animal Science and Central Animal Facility, Hannover Medical School, 30625 Hannover, Germany
    Lab Anim 46:173-5. 2012
    ..Furthermore, anti-mouse IgG is suitable as a secondary antibody for IFA with gerbil serum...