Sonja Körner

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. pmc Weight loss, dysphagia and supplement intake in patients with amyotrophic lateral sclerosis (ALS): impact on quality of life and therapeutic options
    Sonja Körner
    Department of Neurology, Hannover Medical School, Carl Neuberg Str, 1, Hannover 30625, Germany
    BMC Neurol 13:84. 2013
  2. doi request reprint Prevalence and prognostic impact of comorbidities in amyotrophic lateral sclerosis
    S Körner
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Eur J Neurol 20:647-54. 2013
  3. doi request reprint Speech therapy and communication device: impact on quality of life and mood in patients with amyotrophic lateral sclerosis
    Sonja Körner
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Amyotroph Lateral Scler Frontotemporal Degener 14:20-5. 2013
  4. doi request reprint Onset and spreading patterns of upper and lower motor neuron symptoms in amyotrophic lateral sclerosis
    Sonja Körner
    Department of Neurology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Muscle Nerve 43:636-42. 2011
  5. doi request reprint Spontaneous regression of an intracerebral lymphoma (ghost tumor) in a liver-engrafted patient
    Sonja Körner
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Neurologist 17:218-21. 2011
  6. doi request reprint Altered expression of DJ-1 and PINK1 in sporadic ALS and in the SOD1(G93A) ALS mouse model
    Sarah Knippenberg
    From the Department of Neurology, Hannover Medical School SK, JS, NT H, SK, KJR, Rd, SP and Center for Systems Neuroscience RD, SP, Hannover, Germany
    J Neuropathol Exp Neurol 72:1052-61. 2013
  7. doi request reprint CDP-choline is not protective in the SOD1-G93A mouse model of ALS
    Sarah Knippenberg
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Amyotroph Lateral Scler Frontotemporal Degener 14:284-90. 2013
  8. doi request reprint Therapeutic potential of N-acetyl-glucagon-like peptide-1 in primary motor neuron cultures derived from non-transgenic and SOD1-G93A ALS mice
    Hui Sun
    Department of Neurology, Hannover Medical School, OE 7210, Carl Neuberg Strase 1, 30625, Hannover, Germany
    Cell Mol Neurobiol 33:347-57. 2013
  9. doi request reprint Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS?
    Sonja Körner
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Neurodegener Dis 11:141-52. 2013
  10. doi request reprint Decreased mRNA expression of PGC-1α and PGC-1α-regulated factors in the SOD1G93A ALS mouse model and in human sporadic ALS
    Nadine Thau
    Department of Neurology, Hannover Medical School, Hannover, Germany
    J Neuropathol Exp Neurol 71:1064-74. 2012

Collaborators

Detail Information

Publications14

  1. pmc Weight loss, dysphagia and supplement intake in patients with amyotrophic lateral sclerosis (ALS): impact on quality of life and therapeutic options
    Sonja Körner
    Department of Neurology, Hannover Medical School, Carl Neuberg Str, 1, Hannover 30625, Germany
    BMC Neurol 13:84. 2013
    ..In this study we investigated possible causes of weight loss in ALS, its impact on mood/quality of life (QOL) and the benefit of high calorie nutritional/other dietary supplements and percutaneous endoscopic gastrostomy (PEG)...
  2. doi request reprint Prevalence and prognostic impact of comorbidities in amyotrophic lateral sclerosis
    S Körner
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Eur J Neurol 20:647-54. 2013
    ..In this study, we aimed to determine the prevalence of different cardiovascular, metabolic, and neuropsychiatric comorbidities in a large ALS cohort and to evaluate their influence on the disease course...
  3. doi request reprint Speech therapy and communication device: impact on quality of life and mood in patients with amyotrophic lateral sclerosis
    Sonja Körner
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Amyotroph Lateral Scler Frontotemporal Degener 14:20-5. 2013
    ..In conclusion, communication systems improve or at least stabilize quality of life and mood in dysarthric ALS patients, and should be provided early in the disease course...
  4. doi request reprint Onset and spreading patterns of upper and lower motor neuron symptoms in amyotrophic lateral sclerosis
    Sonja Körner
    Department of Neurology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Muscle Nerve 43:636-42. 2011
    ..There is ongoing discussion as to whether ALS is primarily a disease of UMNs or LMNs...
  5. doi request reprint Spontaneous regression of an intracerebral lymphoma (ghost tumor) in a liver-engrafted patient
    Sonja Körner
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Neurologist 17:218-21. 2011
    ..Owing to the high mortality rate associated with this disease, prompt pathologic diagnosis is required to initiate appropriate therapy...
  6. doi request reprint Altered expression of DJ-1 and PINK1 in sporadic ALS and in the SOD1(G93A) ALS mouse model
    Sarah Knippenberg
    From the Department of Neurology, Hannover Medical School SK, JS, NT H, SK, KJR, Rd, SP and Center for Systems Neuroscience RD, SP, Hannover, Germany
    J Neuropathol Exp Neurol 72:1052-61. 2013
    ....
  7. doi request reprint CDP-choline is not protective in the SOD1-G93A mouse model of ALS
    Sarah Knippenberg
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Amyotroph Lateral Scler Frontotemporal Degener 14:284-90. 2013
    ..In conclusion, our data from the transgenic mouse model do not strongly support further clinical validation of CDP-choline for the treatment of ALS...
  8. doi request reprint Therapeutic potential of N-acetyl-glucagon-like peptide-1 in primary motor neuron cultures derived from non-transgenic and SOD1-G93A ALS mice
    Hui Sun
    Department of Neurology, Hannover Medical School, OE 7210, Carl Neuberg Strase 1, 30625, Hannover, Germany
    Cell Mol Neurobiol 33:347-57. 2013
    ....
  9. doi request reprint Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS?
    Sonja Körner
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Neurodegener Dis 11:141-52. 2013
    ..We assessed the expression levels of sirtuins in human postmortem ALS and control brain and spinal cord...
  10. doi request reprint Decreased mRNA expression of PGC-1α and PGC-1α-regulated factors in the SOD1G93A ALS mouse model and in human sporadic ALS
    Nadine Thau
    Department of Neurology, Hannover Medical School, Hannover, Germany
    J Neuropathol Exp Neurol 71:1064-74. 2012
    ..Our data provide evidence for a role of PGC-1α in mitochondrial dysfunction both in the ALS mouse model and in human sporadic ALS that is probably most relevant in the skeletal muscle...
  11. doi request reprint Validation of the German version of the extended ALS functional rating scale as a patient-reported outcome measure
    Susanne Abdulla
    Department of Neurology, Otto von Guericke University Magdeburg, Leipziger Str 44, 39120 Magdeburg, Germany
    J Neurol 260:2242-55. 2013
    ..The German self-report version of the ALSFRS-EX possesses very good psychometric properties similar to the original scale including high internal consistency and test-retest reliability as well as excellent convergent validity...
  12. pmc Magnetic resonance imaging in amyotrophic lateral sclerosis
    Katja Kollewe
    Department of Neurology, Hannover Medical School, 30625 Hannover, Germany
    Neurol Res Int 2012:608501. 2012
    ..In this paper we give an overview of structural and functional MRI alterations in ALS with the focus on task-free resting-state investigations to detect cortical network failures...
  13. doi request reprint Value of quantitative analysis of routine clinical MRI sequences in ALS
    Xiao Qi Ding
    Institute of Diagnostic and Interventional Neuroradiology, Hannover, Germany
    Amyotroph Lateral Scler 12:406-13. 2011
    ..PD therefore appeared to be the most sensitive parameter for the detection of degenerative changes not only in the motor system but also in extramotor brain regions...
  14. pmc Nrf2/ARE Signaling Pathway: Key Mediator in Oxidative Stress and Potential Therapeutic Target in ALS
    Susanne Petri
    Department of Neurology, Hannover Medical School, Hannover, Germany
    Neurol Res Int 2012:878030. 2012
    ....