Therese Koal

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. ncbi request reprint Simultaneous determination of four immunosuppressants by means of high speed and robust on-line solid phase extraction-high performance liquid chromatography-tandem mass spectrometry
    Therese Koal
    Medical School Hannover, Institute of Pharmacology, D 30625, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 805:215-22. 2004
  2. ncbi request reprint Quantification of the carbapenem antibiotic ertapenem in human plasma by a validated liquid chromatography-mass spectrometry method
    Therese Koal
    Hannover Medical School, Institute of Pharmacology, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    Clin Chim Acta 364:239-45. 2006
  3. ncbi request reprint Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography/tandem mass spectrometry
    Therese Koal
    Medical School Hannover, Institute of Pharmacology, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    Rapid Commun Mass Spectrom 19:2995-3001. 2005
  4. ncbi request reprint Direct and fast determination of antiretroviral drugs by automated online solid-phase extraction-liquid chromatography-tandem mass spectrometry in human plasma
    Therese Koal
    Medical School Hannover, Institute of Pharmacology, Hannover, Germany
    Clin Chem Lab Med 44:299-305. 2006
  5. ncbi request reprint Influence of cyclosporine on the serum concentration and biliary excretion of mycophenolic acid and 7-O-mycophenolic acid glucuronide
    Michael Deters
    Institute of Pharmacology, Medical School Hannover, 30623 Hannover, Germany
    Ther Drug Monit 27:132-8. 2005
  6. ncbi request reprint Everolimus/cyclosporine interactions on bile flow and biliary excretion of bile salts and cholesterol in rats
    Michael Deters
    Institute of Pharmacology, Medical School of Hannover, 30623 Hannover, Germany
    Dig Dis Sci 49:30-7. 2004
  7. doi request reprint Different curcuminoids inhibit T-lymphocyte proliferation independently of their radical scavenging activities
    Michael Deters
    Institute of Pharmacology, Hannover Medical School, 30623, Hannover, Germany
    Pharm Res 25:1822-7. 2008
  8. ncbi request reprint Trace determination of priority pesticides in water by means of high-speed on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry using turbulent-flow chromatography columns for enrichment and a short monolithic column for fast liqu
    Arndt Asperger
    Leipzig University, Institute of Analytical Chemistry, Germany
    J Chromatogr A 960:109-19. 2002

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Simultaneous determination of four immunosuppressants by means of high speed and robust on-line solid phase extraction-high performance liquid chromatography-tandem mass spectrometry
    Therese Koal
    Medical School Hannover, Institute of Pharmacology, D 30625, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 805:215-22. 2004
    ..This high throughput technique is perfectly appropriate for routine therapeutic drug monitoring (TDM) of organ transplanted patients...
  2. ncbi request reprint Quantification of the carbapenem antibiotic ertapenem in human plasma by a validated liquid chromatography-mass spectrometry method
    Therese Koal
    Hannover Medical School, Institute of Pharmacology, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    Clin Chim Acta 364:239-45. 2006
    ..LC-MS is the method of choice for therapeutic drug monitoring (TDM) of a variety of drugs including antibiotics. No validated LC-MS method for ertapenem quantification is described in the literature so far...
  3. ncbi request reprint Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography/tandem mass spectrometry
    Therese Koal
    Medical School Hannover, Institute of Pharmacology, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    Rapid Commun Mass Spectrom 19:2995-3001. 2005
    ..DBS preparation as sampling alternative is well suited and practicable for TDM minimizing the high infection risk of HIV/AIDS samples and may facilitate sample mailing...
  4. ncbi request reprint Direct and fast determination of antiretroviral drugs by automated online solid-phase extraction-liquid chromatography-tandem mass spectrometry in human plasma
    Therese Koal
    Medical School Hannover, Institute of Pharmacology, Hannover, Germany
    Clin Chem Lab Med 44:299-305. 2006
    ....
  5. ncbi request reprint Influence of cyclosporine on the serum concentration and biliary excretion of mycophenolic acid and 7-O-mycophenolic acid glucuronide
    Michael Deters
    Institute of Pharmacology, Medical School Hannover, 30623 Hannover, Germany
    Ther Drug Monit 27:132-8. 2005
    ....
  6. ncbi request reprint Everolimus/cyclosporine interactions on bile flow and biliary excretion of bile salts and cholesterol in rats
    Michael Deters
    Institute of Pharmacology, Medical School of Hannover, 30623 Hannover, Germany
    Dig Dis Sci 49:30-7. 2004
    ..From these results we conclude that bile salt synthesis could be impaired by everolimus, which could be one reason for everolimus-induced hypercholesterolemia...
  7. doi request reprint Different curcuminoids inhibit T-lymphocyte proliferation independently of their radical scavenging activities
    Michael Deters
    Institute of Pharmacology, Hannover Medical School, 30623, Hannover, Germany
    Pharm Res 25:1822-7. 2008
    ..We investigated the inhibitory effects of curcumin, curcumin derivatives and degradation products on OKT3-induced human peripheral blood mononuclear cell (PBMC) proliferation and the role of their radical scavenging activity...
  8. ncbi request reprint Trace determination of priority pesticides in water by means of high-speed on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry using turbulent-flow chromatography columns for enrichment and a short monolithic column for fast liqu
    Arndt Asperger
    Leipzig University, Institute of Analytical Chemistry, Germany
    J Chromatogr A 960:109-19. 2002
    ..Concentrations measured (maximum: 16 ng/l simazine in river water) were far below the concentration limits scheduled by law...