Affiliation: Hannover Medical School
- Simultaneous determination of four immunosuppressants by means of high speed and robust on-line solid phase extraction-high performance liquid chromatography-tandem mass spectrometryTherese Koal
Medical School Hannover, Institute of Pharmacology, D 30625, Germany
J Chromatogr B Analyt Technol Biomed Life Sci 805:215-22. 2004..This high throughput technique is perfectly appropriate for routine therapeutic drug monitoring (TDM) of organ transplanted patients...
- Quantification of the carbapenem antibiotic ertapenem in human plasma by a validated liquid chromatography-mass spectrometry methodTherese Koal
Hannover Medical School, Institute of Pharmacology, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
Clin Chim Acta 364:239-45. 2006..LC-MS is the method of choice for therapeutic drug monitoring (TDM) of a variety of drugs including antibiotics. No validated LC-MS method for ertapenem quantification is described in the literature so far...
- Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography/tandem mass spectrometryTherese Koal
Medical School Hannover, Institute of Pharmacology, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
Rapid Commun Mass Spectrom 19:2995-3001. 2005..DBS preparation as sampling alternative is well suited and practicable for TDM minimizing the high infection risk of HIV/AIDS samples and may facilitate sample mailing...
- Direct and fast determination of antiretroviral drugs by automated online solid-phase extraction-liquid chromatography-tandem mass spectrometry in human plasmaTherese Koal
Medical School Hannover, Institute of Pharmacology, Hannover, Germany
Clin Chem Lab Med 44:299-305. 2006....
- Influence of cyclosporine on the serum concentration and biliary excretion of mycophenolic acid and 7-O-mycophenolic acid glucuronideMichael Deters
Institute of Pharmacology, Medical School Hannover, 30623 Hannover, Germany
Ther Drug Monit 27:132-8. 2005....
- Everolimus/cyclosporine interactions on bile flow and biliary excretion of bile salts and cholesterol in ratsMichael Deters
Institute of Pharmacology, Medical School of Hannover, 30623 Hannover, Germany
Dig Dis Sci 49:30-7. 2004..From these results we conclude that bile salt synthesis could be impaired by everolimus, which could be one reason for everolimus-induced hypercholesterolemia...
- Different curcuminoids inhibit T-lymphocyte proliferation independently of their radical scavenging activitiesMichael Deters
Institute of Pharmacology, Hannover Medical School, 30623, Hannover, Germany
Pharm Res 25:1822-7. 2008..We investigated the inhibitory effects of curcumin, curcumin derivatives and degradation products on OKT3-induced human peripheral blood mononuclear cell (PBMC) proliferation and the role of their radical scavenging activity...
- Trace determination of priority pesticides in water by means of high-speed on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry using turbulent-flow chromatography columns for enrichment and a short monolithic column for fast liquArndt Asperger
Leipzig University, Institute of Analytical Chemistry, Germany
J Chromatogr A 960:109-19. 2002..Concentrations measured (maximum: 16 ng/l simazine in river water) were far below the concentration limits scheduled by law...