Affiliation: Hannover Medical School
Trowe M, Maier H, Petry M, Schweizer M, Schuster Gossler K, Kispert A. Impaired stria vascularis integrity upon loss of E-cadherin in basal cells. Dev Biol. 2011;359:95-107 pubmed publisher
Aydoğdu N, Rudat C, Trowe M, Kaiser M, Lüdtke T, Taketo M, et al
. TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018;145: pubmed publisher
Weiss A, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe M, et al
. Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development. 2014;141:3420-30 pubmed publisher
..Disturbed activity of this signaling module may entail defects of the VUJ, which are frequent in the spectrum of congenital anomalies of the kidney and the urinary tract (CAKUT) in human newborns. ..
Weiss A, Kispert A. Eph/ephrin signaling in the kidney and lower urinary tract. Pediatr Nephrol. 2016;31:359-71 pubmed publisher
..With progression of the genetic analyses of mice conditionally mutant for compound alleles of Eph receptor and ephrin ligand genes, additional essential functions are likely to arise in the urinary system. ..
HÃ¤fner R, Bohnenpoll T, Rudat C, Schultheiss T, Kispert A. Fgfr2 is required for the expansion of the early adrenocortical primordium. Mol Cell Endocrinol. 2015;413:168-77 pubmed publisher
..FGFR1 signaling does not contribute to early adrenocortical development. Our work suggests that FGFR2IIIb and IIIc isoforms largely act redundantly to promote expansion of the adrenocortical primordium. ..
Kispert A. T-Box Genes in the Kidney and Urinary Tract. Curr Top Dev Biol. 2017;122:245-278 pubmed publisher
Bohnenpoll T, Weiss A, Labuhn M, Lüdtke T, Trowe M, Kispert A. Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter. Sci Rep. 2017;7:14803 pubmed publisher
..We conclude that RA signaling is required and sufficient to maintain mesenchymal and epithelial progenitors in early ureter development. ..
Greulich F, Trowe M, Leffler A, Stoetzer C, Farin H, Kispert A. Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature. J Mol Cell Cardiol. 2016;97:140-9 pubmed publisher
Lüdtke T, Rudat C, Wojahn I, Weiss A, Kleppa M, Kurz J, et al
. Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung. Dev Cell. 2016;39:239-253 pubmed publisher