J Jungnickel

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. ncbi Faster nerve regeneration after sciatic nerve injury in mice over-expressing basic fibroblast growth factor
    Julia Jungnickel
    Department of Neuroanatomy OE 4140, Center of Anatomy, Hannover Medical School, D 30623 Hannover, Germany
    J Neurobiol 66:940-8. 2006
  2. ncbi Regulation of neuronal death and calcitonin gene-related peptide by fibroblast growth factor-2 and FGFR3 after peripheral nerve injury: evidence from mouse mutants
    J Jungnickel
    Hannover Medical School, Department of Neuroanatomy, Germany
    Neuroscience 134:1343-50. 2005
  3. pmc Myelination in the absence of UDP-galactose:ceramide galactosyl-transferase and fatty acid 2 -hydroxylase
    Marion Meixner
    Institute of Biochemistry and Molecular Biology, University of Bonn, Germany
    BMC Neurosci 12:22. 2011
  4. doi Topology of intrastriatal dopaminergic grafts determines functional and emotional outcome in neurotoxin-lesioned rats
    Julia Jungnickel
    Hannover Medical School, Institute of Neuroanatomy, Hannover, Germany
    Behav Brain Res 216:129-35. 2011
  5. doi Mice lacking basic fibroblast growth factor showed faster sensory recovery
    Julia Jungnickel
    Hannover Medical School, Institute of Neuroanatomy, Germany
    Exp Neurol 223:166-72. 2010
  6. doi Level and localization of polysialic acid is critical for early peripheral nerve regeneration
    Julia Jungnickel
    Hannover Medical School, Institute of Neuroanatomy, Germany
    Mol Cell Neurosci 40:374-81. 2009
  7. ncbi Fibroblast growth factor receptor 3 signaling regulates injury-related effects in the peripheral nervous system
    Julia Jungnickel
    Department of Neuroanatomy OE 4140, Center of Anatomy, Hannover Medical School, D 30623 Hannover, Germany
    Mol Cell Neurosci 25:21-9. 2004
  8. ncbi Targeted disruption of the FGF-2 gene affects the response to peripheral nerve injury
    Julia Jungnickel
    Department of Neuroanatomy OE 4140, Center of Anatomy, Hannover Medical School, D 30623 Hannover, Germany
    Mol Cell Neurosci 25:444-52. 2004
  9. ncbi Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion
    Marco Timmer
    Department of Neuroanatomy, Hannover Medical School, Center for Systems Neuroscience Hannover, 30625 Hannover, Germany
    J Neurosci 27:459-71. 2007
  10. ncbi Physiological function and putative therapeutic impact of the FGF-2 system in peripheral nerve regeneration--lessons from in vivo studies in mice and rats
    Claudia Grothe
    Hannover Medical School, Department of Neuroanatomy, Hannover, Germany
    Brain Res Rev 51:293-9. 2006

Collaborators

Detail Information

Publications11

  1. ncbi Faster nerve regeneration after sciatic nerve injury in mice over-expressing basic fibroblast growth factor
    Julia Jungnickel
    Department of Neuroanatomy OE 4140, Center of Anatomy, Hannover Medical School, D 30623 Hannover, Germany
    J Neurobiol 66:940-8. 2006
    ..We propose that endogenously synthesized FGF-2 influences early peripheral nerve regeneration by regulating Schwann cell proliferation, axonal regrowth, and remyelination...
  2. ncbi Regulation of neuronal death and calcitonin gene-related peptide by fibroblast growth factor-2 and FGFR3 after peripheral nerve injury: evidence from mouse mutants
    J Jungnickel
    Hannover Medical School, Department of Neuroanatomy, Germany
    Neuroscience 134:1343-50. 2005
    ....
  3. pmc Myelination in the absence of UDP-galactose:ceramide galactosyl-transferase and fatty acid 2 -hydroxylase
    Marion Meixner
    Institute of Biochemistry and Molecular Biology, University of Bonn, Germany
    BMC Neurosci 12:22. 2011
    ..In order to test this hypothesis, we have generated Cgt-/- mice with an additional deletion of the fatty acid 2-hydroxylase (Fa2h) gene...
  4. doi Topology of intrastriatal dopaminergic grafts determines functional and emotional outcome in neurotoxin-lesioned rats
    Julia Jungnickel
    Hannover Medical School, Institute of Neuroanatomy, Hannover, Germany
    Behav Brain Res 216:129-35. 2011
    ..These results emphasize the crucial role of graft localization for benefit of restorative cell therapy for PD...
  5. doi Mice lacking basic fibroblast growth factor showed faster sensory recovery
    Julia Jungnickel
    Hannover Medical School, Institute of Neuroanatomy, Germany
    Exp Neurol 223:166-72. 2010
    ..These results suggest that loss of FGF-2 could positively influence restoration of mechanosensory function by accelerating structural recovery transiently...
  6. doi Level and localization of polysialic acid is critical for early peripheral nerve regeneration
    Julia Jungnickel
    Hannover Medical School, Institute of Neuroanatomy, Germany
    Mol Cell Neurosci 40:374-81. 2009
    ....
  7. ncbi Fibroblast growth factor receptor 3 signaling regulates injury-related effects in the peripheral nervous system
    Julia Jungnickel
    Department of Neuroanatomy OE 4140, Center of Anatomy, Hannover Medical School, D 30623 Hannover, Germany
    Mol Cell Neurosci 25:21-9. 2004
    ..Our results suggest that FGFR3 signaling seems to be involved in processes of damage-induced neuron death and axonal development...
  8. ncbi Targeted disruption of the FGF-2 gene affects the response to peripheral nerve injury
    Julia Jungnickel
    Department of Neuroanatomy OE 4140, Center of Anatomy, Hannover Medical School, D 30623 Hannover, Germany
    Mol Cell Neurosci 25:444-52. 2004
    ..Our results suggest that endogenous FGF-2 is crucially involved in the early phase of peripheral nerve regeneration possibly by regulation of Schwann cell differentiation...
  9. ncbi Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion
    Marco Timmer
    Department of Neuroanatomy, Hannover Medical School, Center for Systems Neuroscience Hannover, 30625 Hannover, Germany
    J Neurosci 27:459-71. 2007
    ..The lack of FGF-2 seems to be (over)compensated during development, but, after lesion, compensation mechanisms fail. The transgenic mice showed that endogenous FGF-2 protects DA neurons from 6-OHDA neurotoxicity...
  10. ncbi Physiological function and putative therapeutic impact of the FGF-2 system in peripheral nerve regeneration--lessons from in vivo studies in mice and rats
    Claudia Grothe
    Hannover Medical School, Department of Neuroanatomy, Hannover, Germany
    Brain Res Rev 51:293-9. 2006
    ..Within the group of physiologically relevant trophic factors, the FGF-2 system seems to be crucially involved in the scenario of peripheral nerve development and regeneration...
  11. pmc Fibroblast growth factor-2 regulates the stability of nuclear bodies
    Alexander Francisco Bruns
    Hannover Medical School, Department of Neuroanatomy, Hannover, Germany
    Proc Natl Acad Sci U S A 106:12747-52. 2009
    ..The same effect could be observed in motoneurons of FGF-2 transgenic mice. This study demonstrates the functional role of a growth factor in the regulation of structural entities of the nucleus...