Sabina Janciauskiene

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. ncbi request reprint Detection of Alzheimer peptides and chemokines in the aqueous humor
    Sabina Janciauskiene
    Department of Pulmonology, Hannover Medical School, Hannover, Germany
    Eur J Ophthalmol 21:104-11. 2011
  2. ncbi request reprint Augmentation therapy with alpha1-antitrypsin: novel perspectives
    Janciauskiene Sabina
    Department of Respiratory Medicine, Feodor Lynen Str 23, Hannover Medical School, 30625 Hannover, Germany
    Cardiovasc Hematol Disord Drug Targets 13:90-8. 2013
  3. pmc Lymphocyte and monocyte flow cytometry immunophenotyping as a diagnostic tool in uncharacteristic inflammatory disorders
    Helena Janols
    Department of Infectious Diseases, Skane University Hospital, Lund University, 20502 Malmo, Sweden
    BMC Infect Dis 10:205. 2010
  4. doi request reprint The discovery of α1-antitrypsin and its role in health and disease
    Sabina M Janciauskiene
    Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany
    Respir Med 105:1129-39. 2011
  5. pmc Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase
    Danny Jonigk
    Department of Respiratory Medicine, Institute of Pathology, Central Laboratory Animal Facility, and Institute for Laboratory Animal Science, Hannover Medical School, 30625 Hannover, Germany
    Proc Natl Acad Sci U S A 110:15007-12. 2013
  6. ncbi request reprint Acute-phase protein α1-antitrypsin--a novel regulator of angiopoietin-like protein 4 transcription and secretion
    Eileen Frenzel
    Department of Respiratory Medicine, Hannover Medical School, 30625 Hannover, Germany
    J Immunol 192:5354-62. 2014
  7. ncbi request reprint Effects of alpha 1-antitrypsin on endotoxin-induced lung inflammation in vivo
    Devipriya Subramaniyam
    Department of Respiratory Medicine, Hannover Medical School, Germany
    Inflamm Res 59:571-8. 2010
  8. pmc Acute-phase protein α1-antitrypsin inhibits neutrophil calpain I and induces random migration
    Mariam Al-Omari
    Department of Pulmonology, Hannover Medical School, Hannover, Germany
    Mol Med 17:865-74. 2011
  9. pmc Plexiform lesions in pulmonary arterial hypertension composition, architecture, and microenvironment
    Danny Jonigk
    Institute of Pathology, Hannover Medical School, Hanover, Germany
    Am J Pathol 179:167-79. 2011
  10. ncbi request reprint Allergen-specific immunotherapy increases plasma gelsolin levels
    Sabina Janciauskiene
    Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany
    Am J Rhinol Allergy 28:136-40. 2014

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Detection of Alzheimer peptides and chemokines in the aqueous humor
    Sabina Janciauskiene
    Department of Pulmonology, Hannover Medical School, Hannover, Germany
    Eur J Ophthalmol 21:104-11. 2011
    ....
  2. ncbi request reprint Augmentation therapy with alpha1-antitrypsin: novel perspectives
    Janciauskiene Sabina
    Department of Respiratory Medicine, Feodor Lynen Str 23, Hannover Medical School, 30625 Hannover, Germany
    Cardiovasc Hematol Disord Drug Targets 13:90-8. 2013
    ..Hence, in this article we will discuss putative new directions for the clinical use of therapy with AAT. ..
  3. pmc Lymphocyte and monocyte flow cytometry immunophenotyping as a diagnostic tool in uncharacteristic inflammatory disorders
    Helena Janols
    Department of Infectious Diseases, Skane University Hospital, Lund University, 20502 Malmo, Sweden
    BMC Infect Dis 10:205. 2010
    ....
  4. doi request reprint The discovery of α1-antitrypsin and its role in health and disease
    Sabina M Janciauskiene
    Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany
    Respir Med 105:1129-39. 2011
    ..In this review co-occurrence of several diseases with AAT deficiency is discussed...
  5. pmc Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase
    Danny Jonigk
    Department of Respiratory Medicine, Institute of Pathology, Central Laboratory Animal Facility, and Institute for Laboratory Animal Science, Hannover Medical School, 30625 Hannover, Germany
    Proc Natl Acad Sci U S A 110:15007-12. 2013
    ..These data provide evidence that the anti-inflammatory and immunomodulatory properties of AAT can be independent of elastase inhibition. ..
  6. ncbi request reprint Acute-phase protein α1-antitrypsin--a novel regulator of angiopoietin-like protein 4 transcription and secretion
    Eileen Frenzel
    Department of Respiratory Medicine, Hannover Medical School, 30625 Hannover, Germany
    J Immunol 192:5354-62. 2014
    ..In contrast, the forced accumulation of HIF-1α, an upregulator of angptl4 expression, enhanced the effect of A1AT. Thus, acute-phase protein A1AT is a physiological regulator of angptl4, another acute-phase protein. ..
  7. ncbi request reprint Effects of alpha 1-antitrypsin on endotoxin-induced lung inflammation in vivo
    Devipriya Subramaniyam
    Department of Respiratory Medicine, Hannover Medical School, Germany
    Inflamm Res 59:571-8. 2010
    ..Here we investigate how AAT regulates inflammatory responses in the short term when administrated post LPS challenge...
  8. pmc Acute-phase protein α1-antitrypsin inhibits neutrophil calpain I and induces random migration
    Mariam Al-Omari
    Department of Pulmonology, Hannover Medical School, Hannover, Germany
    Mol Med 17:865-74. 2011
    ....
  9. pmc Plexiform lesions in pulmonary arterial hypertension composition, architecture, and microenvironment
    Danny Jonigk
    Institute of Pathology, Hannover Medical School, Hanover, Germany
    Am J Pathol 179:167-79. 2011
    ..Neoplastic models of angiogenesis seem to be of limited use in further study of plexiform vasculopathy...
  10. ncbi request reprint Allergen-specific immunotherapy increases plasma gelsolin levels
    Sabina Janciauskiene
    Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany
    Am J Rhinol Allergy 28:136-40. 2014
    ..This study was designed to explore the idea that the markers of apoptosis may help predict the response of allergen immunotherapy...
  11. pmc Krüppel-like zinc finger proteins in end-stage COPD lungs with and without severe alpha1-antitrypsin deficiency
    A Rembert Koczulla
    Institute of Pathology, Hannover Medical School, Hanover, Germany
    Orphanet J Rare Dis 7:29. 2012
    ..A study was undertaken to investigate gene expression patterns in end-stage COPD lungs from patients with and without AATD...
  12. doi request reprint Secretory leukocyte protease inhibitor inhibits neutrophil apoptosis
    Devipriya Subramaniyam
    Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany
    Respirology 16:300-7. 2011
    ..In addition to its anti-protease activity, SLPI has been shown to express anti-bacterial, anti-viral and anti-inflammatory properties...
  13. doi request reprint Performance of enhanced liver fibrosis plasma markers in asymptomatic individuals with ZZ α1-antitrypsin deficiency
    Sabina Janciauskiene
    Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany
    Eur J Gastroenterol Hepatol 23:716-20. 2011
    ..We hypothesized that the plasma markers for liver fibrosis, necrosis, and apoptosis may identify AATD individuals at higher risk for liver diseases...
  14. ncbi request reprint Alpha-1-antitrypsin inhibits acute liver failure in mice
    Nils Jedicke
    Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany Chronic Infection and Cancer Group, Helmholtz Center for Infection Research, Braunschweig, Germany Division of translational Gastrointestinal Oncology, Department of Internal Medicine I, University Hospital Tuebingen, Tubingen, Germany
    Hepatology 59:2299-308. 2014
    ..Conclusion: Our data suggest that systemic administration of AAT can be a promising therapy to treat acute liver failure and clinical studies to explore this treatment in humans should be initiated. (Hepatology 2014;59:2299-2308). ..
  15. doi request reprint Plexiform vasculopathy of severe pulmonary arterial hypertension and microRNA expression
    Clemens L Bockmeyer
    Institute of Pathology, Hannover Medical School, Hannover, Germany
    J Heart Lung Transplant 31:764-72. 2012
    ..Specific miRNAs in plexiform vasculopathy of severe pulmonary arterial hypertension (PAH) in humans have not yet been investigated...
  16. doi request reprint Diagnostic delay and clinical modifiers in alpha-1 antitrypsin deficiency
    Thomas Köhnlein
    Hannover Medical School, Respiratory Medicine, Carl Neuberg Strasse 1, Hannover, Germany
    Ther Adv Respir Dis 4:279-87. 2010
    ..This study assessed the latencies and numbers of physicians involved in identifying AATD patients, and the importance of smoking, vaccination status, and specific augmentation therapy on the course of the disease...
  17. ncbi request reprint Cholesterol rich lipid raft microdomains are gateway for acute phase protein, SERPINA1
    Devipriya Subramaniyam
    Hannover Medical School, Department of Respiratory Medicine, Feodor Lynen Str 23, 30625 Hannover, Germany
    Int J Biochem Cell Biol 42:1562-70. 2010
    ..Our findings for the first time highlight that the entry and cell association of SERPINA1 is dependent on lipid raft cholesterol and that SERPINA1 depletes lipid raft cholesterol...