Sabine Illsinger

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. ncbi request reprint Effect of tacrolimus on energy metabolism in human umbilical endothelial cells
    Sabine Illsinger
    Clinic for Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Germany
    Ann Transplant 16:68-75. 2011
  2. doi request reprint Scheie syndrome: enzyme replacement therapy does not prevent progression of cervical myelopathy due to spinal cord compression
    S Illsinger
    Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl Neuberg Str 1, 30625, Hannover, Germany
    J Inherit Metab Dis 32:S321-5. 2009
  3. doi request reprint Impact of selected inborn errors of metabolism on prenatal and neonatal development
    Sabine Illsinger
    Clinic for Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Germany
    IUBMB Life 62:403-13. 2010
  4. doi request reprint Preeclampsia and HELLP syndrome: impaired mitochondrial function in umbilical endothelial cells
    Sabine Illsinger
    Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    Reprod Sci 17:219-26. 2010
  5. doi request reprint Carnitine-palmitoyltransferase 2 deficiency: novel mutations and relevance of newborn screening
    Sabine Illsinger
    Department of Pediatric Kidney, Liver and Metabolic Diseases, Children s Hospital Hannover Medical School, Hannover, Germany
    Am J Med Genet A 146:2925-8. 2008
  6. doi request reprint Energy metabolism in umbilical endothelial cells from preterm and term neonates
    Sabine Illsinger
    Clinic for Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    J Perinat Med 39:587-93. 2011
  7. doi request reprint Cyclosporine A: impact on mitochondrial function in endothelial cells
    Sabine Illsinger
    Clinic for Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    Clin Transplant 25:584-93. 2011
  8. doi request reprint Increased asymmetric dimethylarginine (ADMA) dimethylaminohydrolase (DDAH) activity in childhood hypercholesterolemia type II
    Kristine Chobanyan-Jürgens
    Department of Paediatrics, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Amino Acids 43:805-11. 2012
  9. doi request reprint Early cataract formation due to galactokinase deficiency: impact of newborn screening
    Nils Janzen
    Clinic for Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    Arch Med Res 42:608-12. 2011
  10. ncbi request reprint Isolated mitochondrial long-chain ketoacyl-CoA thiolase deficiency resulting from mutations in the HADHB gene
    Anibh M Das
    Department of Paediatrics, Hannover Medical School, Hannover, Germany
    Clin Chem 52:530-4. 2006

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Effect of tacrolimus on energy metabolism in human umbilical endothelial cells
    Sabine Illsinger
    Clinic for Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Germany
    Ann Transplant 16:68-75. 2011
    ..Tacrolimus has a wide spectrum of adverse effects, including neurotoxic and vascular events. Vascular dysfunction due to interference of tacrolimus with mitochondrial function in endothelial cells may contribute to these adverse reactions...
  2. doi request reprint Scheie syndrome: enzyme replacement therapy does not prevent progression of cervical myelopathy due to spinal cord compression
    S Illsinger
    Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl Neuberg Str 1, 30625, Hannover, Germany
    J Inherit Metab Dis 32:S321-5. 2009
    ..Clinical significance of cerebral changes is unclear. Whether early HCT or intrathecal ERT could have prevented these lesions remains speculative...
  3. doi request reprint Impact of selected inborn errors of metabolism on prenatal and neonatal development
    Sabine Illsinger
    Clinic for Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Germany
    IUBMB Life 62:403-13. 2010
    ..For these disorders, the pathophysiology of early manifestation, special aspects regarding the prenatal and neonatal period, and diagnostic as well as therapeutic options are presented...
  4. doi request reprint Preeclampsia and HELLP syndrome: impaired mitochondrial function in umbilical endothelial cells
    Sabine Illsinger
    Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    Reprod Sci 17:219-26. 2010
    ..Impaired mitochondrial function in HUVEC is associated with PE/HELLP syndrome and may be involved in the pathophysiology of these diseases...
  5. doi request reprint Carnitine-palmitoyltransferase 2 deficiency: novel mutations and relevance of newborn screening
    Sabine Illsinger
    Department of Pediatric Kidney, Liver and Metabolic Diseases, Children s Hospital Hannover Medical School, Hannover, Germany
    Am J Med Genet A 146:2925-8. 2008
    ..Biochemical testing of urine (organic acids) may be unrevealing...
  6. doi request reprint Energy metabolism in umbilical endothelial cells from preterm and term neonates
    Sabine Illsinger
    Clinic for Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    J Perinat Med 39:587-93. 2011
    ..The aim of this study was to investigate the impact of gestational age on energy metabolism in human umbilical vein endothelial cells (HUVECs) of preterm and term neonates...
  7. doi request reprint Cyclosporine A: impact on mitochondrial function in endothelial cells
    Sabine Illsinger
    Clinic for Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    Clin Transplant 25:584-93. 2011
    ..Interference of CSA with mitochondrial function may be responsible for these side effects...
  8. doi request reprint Increased asymmetric dimethylarginine (ADMA) dimethylaminohydrolase (DDAH) activity in childhood hypercholesterolemia type II
    Kristine Chobanyan-Jürgens
    Department of Paediatrics, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Amino Acids 43:805-11. 2012
    ..While this would tend to limit development of endothelial dysfunction, it is not clear whether this might be medication-induced or represent a primary change in HCh-II children...
  9. doi request reprint Early cataract formation due to galactokinase deficiency: impact of newborn screening
    Nils Janzen
    Clinic for Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany
    Arch Med Res 42:608-12. 2011
    ..The aim of this retrospective study was to explore whether GALK-deficiency meets the criteria for neonatal mass screening programs...
  10. ncbi request reprint Isolated mitochondrial long-chain ketoacyl-CoA thiolase deficiency resulting from mutations in the HADHB gene
    Anibh M Das
    Department of Paediatrics, Hannover Medical School, Hannover, Germany
    Clin Chem 52:530-4. 2006
    ..Isolated LCTH deficiency with mutations in the HADHB gene has not been reported. Patient and..
  11. doi request reprint Glycogen storage disease type 1: impact of medium-chain triglycerides on metabolic control and growth
    Anibh M Das
    Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany das anibh mh hannover de
    Ann Nutr Metab 56:225-32. 2010
    ..We studied the effect of a diet enriched in medium-chain triglycerides (MCT) on metabolic control/growth in GSD 1 as medium-chain fatty acids can be oxidised independently of CPT 1...
  12. doi request reprint Plasma and urine amino acid pattern in preterm infants on enteral nutrition: impact of gestational age
    Sabine Illsinger
    Department of Paediatric Kidney, Liver and Metabolic Diseases, Children s Hospital, Hannover Medical School, Carl Neuberg Str 1, 30625 Hannover, Germany
    Amino Acids 38:959-72. 2010
    ..Our data clearly indicate the heterogeneity of the preterm cohort; therefore, gestational age-matched reference values have to be used for diagnostic purposes in preterm infants...
  13. pmc Inborn errors of energy metabolism associated with myopathies
    Anibh M Das
    Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl Neuberg Street 1, 30625 Hannover, Germany
    J Biomed Biotechnol 2010:340849. 2010
    ..e., mitochondriopathies). The diagnostic work-up and therapeutic options in these disorders are discussed...
  14. ncbi request reprint Pitfalls in paediatric gait disturbances: painless bone diseases
    Thomas Lücke
    Klinik fur Kinder und Jugendliche, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30623, Hannover, Germany
    Eur J Pediatr 165:909-12. 2006
    ....
  15. ncbi request reprint Fabry disease: reduced activities of respiratory chain enzymes with decreased levels of energy-rich phosphates in fibroblasts
    Thomas Lücke
    Department of Pediatrics, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Mol Genet Metab 82:93-7. 2004
    ..As in NCL, lysosomal storage material may lead to mitochondrial dysfunction with a reduction of respiratory chain enzyme activities and a subsequent drop in cellular levels of energy-rich phosphates...
  16. doi request reprint Asymmetric dimethylarginine in children with homocystinuria or phenylketonuria
    Nele Kanzelmeyer
    Department of Pediatrics, Medical School Hannover, Carl Neuberg Str 1, 30625, Hannover, Germany
    Amino Acids 42:1765-72. 2012
    ..In phenylketonuria, the L-arginine/NO pathway seems not be altered. Delineation of the role of ADMA in childhood phenylketonuria and homocystinuria demands further investigation...
  17. ncbi request reprint Status epilepticus and hyperprolinaemia following recurrent gelatine administrations in a patient on peritoneal dialysis
    Sabine Illsinger
    Department of Paediatrics, Medical School Hanover, Carl Neuberg Str 1, D 30623 Hanover, Germany
    Nephrol Dial Transplant 21:1417-9. 2006