Alexander A Hanke

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. pmc Impact of platelet count on results obtained from multiple electrode platelet aggregometry (Multiplate)
    A A Hanke
    Klinik für Anästhesiologie und Intensivmedizin, Medizinische Hochschule Hannover, Hannover, Germany
    Eur J Med Res 15:214-9. 2010
  2. doi [Trauma-induced coagulopathy]
    A A Hanke
    Klinik für Anästhesiologie und Intensivmedizin, Medizinische Hochschule Hannover, Carl Neuberg Strase 1, 30625, Hannover, Deutschland
    Unfallchirurg 117:95-8. 2014
  3. doi Long-term safety and efficacy of a pasteurized nanofiltrated prothrombin complex concentrate (Beriplex P/N): a pharmacovigilance study
    A A Hanke
    Department of Anesthesiology and Intensive Care, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Br J Anaesth 110:764-72. 2013
  4. pmc Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy
    Herbert Schöchl
    Ludwig Boltzmann Institute of Experimental and Clinical Traumatology, Donaueschingenstrasse 13, A 1200 Vienna, Austria
    Crit Care 15:R83. 2011
  5. doi Comparison of Flexiblade and Macintosh laryngoscopes: cervical extension angles during orotracheal intubation
    S Uzun
    Anaesthesiology and Reanimation Department, Hacettepe University Faculty of Medicine, Ankara, Turkey
    Anaesthesia 65:692-6. 2010
  6. pmc In vitro impairment of whole blood coagulation and platelet function by hypertonic saline hydroxyethyl starch
    Alexander A Hanke
    Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Germany
    Scand J Trauma Resusc Emerg Med 19:12. 2011
  7. doi Potential of whole blood coagulation reconstitution by desmopressin and fibrinogen under conditions of hypothermia and acidosis--an in vitro study using rotation thrombelastometry
    Alexander A Hanke
    Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
    Scand J Clin Lab Invest 71:292-8. 2011
  8. doi First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen, Germany
    Anesthesiology 115:1179-91. 2011
  9. doi Potential value of transfusion protocols in cardiac surgery
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Universitat Duisburg Essen, Essen, Germany
    Curr Opin Anaesthesiol 26:230-43. 2013
  10. doi Hypothermia and acidosis synergistically impair coagulation in human whole blood
    Daniel Dirkmann
    Klinik für Anästhesiologie und Intensivmedizin, Universitat Duisburg Essen, Universitatsklinikum Essen, Essen, Germany
    Anesth Analg 106:1627-32. 2008

Detail Information

Publications11

  1. pmc Impact of platelet count on results obtained from multiple electrode platelet aggregometry (Multiplate)
    A A Hanke
    Klinik für Anästhesiologie und Intensivmedizin, Medizinische Hochschule Hannover, Hannover, Germany
    Eur J Med Res 15:214-9. 2010
    ..We tested the hypothesis that results of multiple electrode platelet aggregometry are affected by platelet count, in particular if platelet count is below normal range...
  2. doi [Trauma-induced coagulopathy]
    A A Hanke
    Klinik für Anästhesiologie und Intensivmedizin, Medizinische Hochschule Hannover, Carl Neuberg Strase 1, 30625, Hannover, Deutschland
    Unfallchirurg 117:95-8. 2014
    ..TIC is a complex independent syndrome which may be present without initial hypercoagulopathy. A rapid and differentiated diagnosis and goal-directed therapy is crucial for causal therapy. ..
  3. doi Long-term safety and efficacy of a pasteurized nanofiltrated prothrombin complex concentrate (Beriplex P/N): a pharmacovigilance study
    A A Hanke
    Department of Anesthesiology and Intensive Care, Hannover Medical School, Carl Neuberg Str 1, D 30625 Hannover, Germany
    Br J Anaesth 110:764-72. 2013
    ....
  4. pmc Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy
    Herbert Schöchl
    Ludwig Boltzmann Institute of Experimental and Clinical Traumatology, Donaueschingenstrasse 13, A 1200 Vienna, Austria
    Crit Care 15:R83. 2011
    ....
  5. doi Comparison of Flexiblade and Macintosh laryngoscopes: cervical extension angles during orotracheal intubation
    S Uzun
    Anaesthesiology and Reanimation Department, Hacettepe University Faculty of Medicine, Ankara, Turkey
    Anaesthesia 65:692-6. 2010
    ..The decreased extension angle between C1-C2 during Flexiblade laryngoscopy compared with Macintosh laryngoscopy may be an advantage where neurological damage with cervical movement is a concern...
  6. pmc In vitro impairment of whole blood coagulation and platelet function by hypertonic saline hydroxyethyl starch
    Alexander A Hanke
    Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Germany
    Scand J Trauma Resusc Emerg Med 19:12. 2011
    ..Furthermore 7.2% hypertonic saline, 6% hydroxyethylstarch (as ingredients of HH), and 0.9% saline solution (as control) were tested in comparable dilutions to estimate specific component effects of HH on coagulation...
  7. doi Potential of whole blood coagulation reconstitution by desmopressin and fibrinogen under conditions of hypothermia and acidosis--an in vitro study using rotation thrombelastometry
    Alexander A Hanke
    Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
    Scand J Clin Lab Invest 71:292-8. 2011
    ..Desmopressin (DDAVP) and fibrinogen improve platelet function and clot stability. We investigated the influence of DDAVP and fibrinogen on whole blood coagulation in an in vitro model of hypothermia and acidosis...
  8. doi First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen, Germany
    Anesthesiology 115:1179-91. 2011
    ..We developed and implemented an algorithm for coagulation management in cardiovascular surgery based on first-line administration of coagulation factor concentrates combined with point-of-care thromboelastometry/impedance aggregometry...
  9. doi Potential value of transfusion protocols in cardiac surgery
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Universitat Duisburg Essen, Essen, Germany
    Curr Opin Anaesthesiol 26:230-43. 2013
    ..The 16 studies fitting these search criteria have evaluated the impact of the implementation of ROTEM/TEG based coagulation management algorithms on transfusion requirement and outcome in overall 8507 cardiovascular surgical patients...
  10. doi Hypothermia and acidosis synergistically impair coagulation in human whole blood
    Daniel Dirkmann
    Klinik für Anästhesiologie und Intensivmedizin, Universitat Duisburg Essen, Universitatsklinikum Essen, Essen, Germany
    Anesth Analg 106:1627-32. 2008
    ..Hypothermia and acidosis were reported to influence coagulopathy in different clinical settings. We evaluated whole blood coagulation to determine the effects of hypothermia and/or acidosis on hemostasis...
  11. doi Effects of desmopressin on platelet function under conditions of hypothermia and acidosis: an in vitro study using multiple electrode aggregometry*
    A A Hanke
    Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
    Anaesthesia 65:688-91. 2010
    ..During acidosis and hypothermia, acidosis should be corrected first; desmopressin can then be administered to improve platelet function as a bridge until normothermia can be achieved...