G Haeseler


Affiliation: Hannover Medical School
Country: Germany


  1. request reprint
    Haeseler G, Maue D, Grosskreutz J, Bufler J, Nentwig B, Piepenbrock S, et al. Voltage-dependent block of neuronal and skeletal muscle sodium channels by thymol and menthol. Eur J Anaesthesiol. 2002;19:571-9 pubmed
  2. request reprint
    Haeseler G, Foadi N, Ahrens J, Dengler R, Hecker H, Leuwer M. Tramadol, fentanyl and sufentanil but not morphine block voltage-operated sodium channels. Pain. 2006;126:234-44 pubmed
    ..2) Slow inactivation--a physiological mechanism to suppress ectopic activity in response to slow shifts in membrane potential--increases binding affinity for sufentanil, fentanyl and tramadol. (3) Morphine has no such effects. ..
  3. Haeseler G, Ahrens J, Krampfl K, Bufler J, Dengler R, Hecker H, et al. Structural features of phenol derivatives determining potency for activation of chloride currents via alpha(1) homomeric and alpha(1)beta heteromeric glycine receptors. Br J Pharmacol. 2005;145:916-25 pubmed
    ..The presence of the beta subunit is not required for both effects. ..