Olaf Dammann

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. ncbi request reprint Lung and brain damage in preterm newborns. Are they related? How? Why?
    Olaf Dammann
    Departments of Obstetrics and Pediatrics, Perinatal Infectious Disease Epidemiology Unit, Hannover Medical School, Hannover, Germany
    Biol Neonate 85:305-13. 2004
  2. ncbi request reprint Coagulation, inflammation, and the risk of neonatal white matter damage
    Alan Leviton
    Neuroepidemiology Unit, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Pediatr Res 55:541-5. 2004
  3. ncbi request reprint Absence of pestivirus antigen in brains with white matter damage
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Hannover Medical School, Germany
    Dev Med Child Neurol 48:290-3. 2006
  4. ncbi request reprint Inflammation, brain damage and visual dysfunction in preterm infants
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Department of Gynecology, Hannover Medical School, OE 6415, 30623 Hannover, Germany
    Semin Fetal Neonatal Med 11:363-8. 2006
  5. ncbi request reprint [Intrauterine infection and the preterm brain: dimensions of aetiology research]
    O Dammann
    Perinatale Infektionsepidemiologie, OE6415 Abteilung für Gynäkologie und Geburtshilfe, sowie Abteilung für Kinderheilkunde, Pädiatrische Pneumologie und Neonatologie, Medizinische Hochschule Hannover
    Z Geburtshilfe Neonatol 210:1-5. 2006
  6. ncbi request reprint Evidence-based child neurology
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Department of Obstetrics, Hannover Medical School, Hannover, Germany
    Dev Med Child Neurol 48:622-4. 2006
  7. ncbi request reprint Paediatric neurology: the many faces of development
    Olaf Dammann
    Hannover Medical School, Hannover, Germany
    Lancet Neurol 6:12-4. 2007
  8. ncbi request reprint Inflammatory brain damage in preterm newborns--dry numbers, wet lab, and causal inferences
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Hannover Medical School, Germany
    Early Hum Dev 79:1-15. 2004
  9. ncbi request reprint Persistent neuro-inflammation in cerebral palsy: a therapeutic window of opportunity?
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, OE6415, Department of Obstetrics, Hannover Medical School, 30623 Hannover, Germany
    Acta Paediatr 96:6-7. 2007
  10. ncbi request reprint Bronchopulmonary dysplasia is not associated with ultrasound-defined cerebral white matter damage in preterm newborns
    Olaf Dammann
    Department of Obstetrics, Prenatal Medicine and Gynecology, Hannover Medical School, 30623 Hannover, Germany
    Pediatr Res 55:319-25. 2004

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Lung and brain damage in preterm newborns. Are they related? How? Why?
    Olaf Dammann
    Departments of Obstetrics and Pediatrics, Perinatal Infectious Disease Epidemiology Unit, Hannover Medical School, Hannover, Germany
    Biol Neonate 85:305-13. 2004
    ..g. postnatal steroid exposure) that increase the risk for developmental disability in childhood...
  2. ncbi request reprint Coagulation, inflammation, and the risk of neonatal white matter damage
    Alan Leviton
    Neuroepidemiology Unit, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Pediatr Res 55:541-5. 2004
    ....
  3. ncbi request reprint Absence of pestivirus antigen in brains with white matter damage
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Hannover Medical School, Germany
    Dev Med Child Neurol 48:290-3. 2006
    ..Further research is needed to test the hypothesis that intrauterine exposure to pestivirus antigen elicits a fetal inflammatory response which then contributes to WMD...
  4. ncbi request reprint Inflammation, brain damage and visual dysfunction in preterm infants
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Department of Gynecology, Hannover Medical School, OE 6415, 30623 Hannover, Germany
    Semin Fetal Neonatal Med 11:363-8. 2006
    ....
  5. ncbi request reprint [Intrauterine infection and the preterm brain: dimensions of aetiology research]
    O Dammann
    Perinatale Infektionsepidemiologie, OE6415 Abteilung für Gynäkologie und Geburtshilfe, sowie Abteilung für Kinderheilkunde, Pädiatrische Pneumologie und Neonatologie, Medizinische Hochschule Hannover
    Z Geburtshilfe Neonatol 210:1-5. 2006
    ..viral infection; and (7) preterm vs. term delivery. Despite these complexities, it is hoped that obstetricians, neonatologists, and neuropaediatricians will agree on a perinatal neuroprotective strategy in the near future...
  6. ncbi request reprint Evidence-based child neurology
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Department of Obstetrics, Hannover Medical School, Hannover, Germany
    Dev Med Child Neurol 48:622-4. 2006
    ..Therefore, evidence-based child neurology might benefit not only from the therapeutic, but also from the diagnostic and etiological components of epidemiology...
  7. ncbi request reprint Paediatric neurology: the many faces of development
    Olaf Dammann
    Hannover Medical School, Hannover, Germany
    Lancet Neurol 6:12-4. 2007
  8. ncbi request reprint Inflammatory brain damage in preterm newborns--dry numbers, wet lab, and causal inferences
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Hannover Medical School, Germany
    Early Hum Dev 79:1-15. 2004
    ..We also need more (and more detailed) observational studies clarifying the presumed infection --> inflammation --> WMD sequence before we can initiate intervention trials to reduce the risk of WMD...
  9. ncbi request reprint Persistent neuro-inflammation in cerebral palsy: a therapeutic window of opportunity?
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, OE6415, Department of Obstetrics, Hannover Medical School, 30623 Hannover, Germany
    Acta Paediatr 96:6-7. 2007
  10. ncbi request reprint Bronchopulmonary dysplasia is not associated with ultrasound-defined cerebral white matter damage in preterm newborns
    Olaf Dammann
    Department of Obstetrics, Prenatal Medicine and Gynecology, Hannover Medical School, 30623 Hannover, Germany
    Pediatr Res 55:319-25. 2004
    ..Confounding does not seem to account for this lack of association between WMD and BPD. In conclusion, our findings do not support the hypothesis that BPD contributes to the occurrence of sonographically defined WMD...
  11. ncbi request reprint Maternal fever at birth and non-verbal intelligence at age 9 years in preterm infants
    Olaf Dammann
    Department of Obstetrics, Prenatal Medicine, and General Gynecology, Hannover Medical School, Germany
    Dev Med Child Neurol 45:148-51. 2003
    ..8, 0.97 to 14.6). We conclude that perinatal infection might indeed contribute to an increased risk for long-term cognitive deficits in preterm infants...
  12. pmc Neuregulin-1, the fetal endothelium, and brain damage in preterm newborns
    Insa Hoffmann
    Pediatric Pulmonology and Neonatology, Hannover Medical School, Hannover, Germany
    Brain Behav Immun 24:784-91. 2010
    ..To assess the potential role for Neuregulin-1 (NRG1) as a systemic endogenous protector in the setting of perinatal inflammatory brain damage...
  13. ncbi request reprint Nijmegen Breakage Syndrome mutations and risk of breast cancer
    Natalia Bogdanova
    Gynecology Research Unit, Hannover Medical School, Hannover, Germany
    Int J Cancer 122:802-6. 2008
    ..1; 95%CI 1.4-6.6) and indicate that the 657del5 deletion and perhaps the R215W substitution contribute to inherited breast cancer susceptibility in Central and Eastern Europe...
  14. pmc Endoplasmic reticulum stress, inflammation, and perinatal brain damage
    Wolfgang Bueter
    Perinatal Neuroepidemiology Unit OE 6415, Departments of Obstetrics and Pediatrics, Hannover Medical School, Hannover, Germany
    Pediatr Res 66:487-94. 2009
    ..Perhaps by these events, noninflammatory stimuli lead to perinatal brain damage...
  15. ncbi request reprint Lung and brain damage in preterm newborns, and their association with gestational age, prematurity subgroup, infection/inflammation and long term outcome
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, Department of Obstetrics and Pediatrics, OE 6415 Hannover Medical School, 30623 Hannover, Germany
    BJOG 112:4-9. 2005
    ..In this paper we discuss the complexities that paediatricians, perinatologists and perinatal epidemiologists face as they try to understand the contributions of factors associated with preterm birth to neonatal and childhood disorders...
  16. ncbi request reprint Multiplex measurement of cytokine/receptor gene polymorphisms and interaction between interleukin-10 (-1082) genotype and chorioamnionitis in extreme preterm delivery
    Julia Kerk
    Department of Gynecology and Obstetrics, Hannover Medical School, Hannover, Germany
    J Soc Gynecol Investig 13:350-6. 2006
    ....
  17. doi request reprint Simulation of intra-amniotic infection and the fetal inflammatory response in a novel ex-vivo human umbilical cord perfusion model
    Sarah Hassan
    Pediatric Pulmonology and Neonatology, Hannover Medical School, Hannover, Germany
    Reprod Sci 17:426-33. 2010
    ..We aimed to design and test an ex-vivo human umbilical cord (HUC) perfusion model simulating a fetal inflammatory response (FIR) during intra-amniotic infection...
  18. ncbi request reprint NEUROBID--an EU-funded project to study the developing brain barriers
    Wolfgang Bueter
    Hannover Medical School, Hannover, Germany
    Int J Dev Neurosci 28:411-2. 2010
    ..In the long term, NEUROBID hopes to pave the way for new treatment strategies and thus reduce the economic and social burden of neurological disease...
  19. ncbi request reprint Antenatal mycoplasma infection, the fetal inflammatory response and cerebral white matter damage in very-low-birthweight infants
    Olaf Dammann
    Hannover Medical School, Germany
    Paediatr Perinat Epidemiol 17:49-57. 2003
    ..Our finding that M. hominis in the placenta was associated with a not quite significant threefold risk increase for echolucency deserves further investigation...
  20. ncbi request reprint Hospital volume and neonatal mortality among very low birth weight infants
    Dorothee B Bartels
    Department of Obstetrics, Social Medicine and Health System Research, Hannover Medical School, Hannover, Germany
    Pediatrics 117:2206-14. 2006
    ..We hypothesized that neonatal mortality would be higher in small NICUs (< 36 very low birth weight admissions per year) than in large NICUs, with adjustment for volume of the delivery unit...
  21. pmc ErbB receptors in fetal endothelium--a potential linkage point for inflammation-associated neonatal disorders
    Wolfgang Bueter
    Department of Pediatrics, Hannover Medical School, Carl Neuberg Str 1, 30623 Hannover, Germany
    Cytokine 36:267-75. 2006
    ..It is still unclear, whether expression patterns might be developmentally regulated and depend on the cell type studied...
  22. ncbi request reprint Protein detection in dried blood by surface-enhanced laser desorption/ionization-time of flight mass spectrometry (SELDI-TOF MS)
    Christiane E L Dammann
    Department of Pediatric Pulmonology and Neonatology, Hannover Medical School, Hannover, Germany
    Biol Neonate 89:126-32. 2006
    ..The rapid and reliable identification of biomarkers in the smallest possible amount of blood remains a challenge in biomarker epidemiological research involving preterm newborns...
  23. ncbi request reprint Perinatal brain damage causation
    Olaf Dammann
    Perinatal Infectious Disease Epidemiology Unit, OE 6415, Hannover Medical School, Hannover, Germany
    Dev Neurosci 29:280-8. 2007
    ..We hope that our critical discussion will contribute to fruitful research and help reduce the burden of perinatal brain damage...
  24. doi request reprint Intermittent or sustained systemic inflammation and the preterm brain
    Olaf Dammann
    1 Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, Massachusetts 2 Division of Newborn Medicine, Department of Neurology, Floating Hospital for Children at Tufts Medical Center, Boston, Massachusetts 3 Perinatal Neuroepidemiology Unit, Hannover Medical School, Hannover, Germany
    Pediatr Res 75:376-80. 2014
    ....
  25. ncbi request reprint Association of two mutations in the CHEK2 gene with breast cancer
    Natalia Bogdanova
    Gynecology Research Unit, Hannover Medical School, Hannover, Germany
    Int J Cancer 116:263-6. 2005
    ..Family history of breast cancer did not differ between carriers and noncarriers. Our data indicate that the I157T allele, and possibly the IVS2+1G > A allele, of the CHEK2 gene contribute to inherited breast cancer susceptibility...
  26. ncbi request reprint Systemic hypotension and white-matter damage in preterm infants
    Olaf Dammann
    Children s Hospital, Boston, MA 02115, USA
    Dev Med Child Neurol 44:82-90. 2002
    ..In sum, these results do not support the hypothesis that systemic hypotension contributes to echolucency among preterm infants...
  27. ncbi request reprint Chorioamnionitis, mechanical ventilation, and postnatal sepsis as modulators of chronic lung disease in preterm infants
    Linda J Van Marter
    Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Pediatr 140:171-6. 2002
    ..This case-control study of chronic lung disease (CLD) evaluated the hypothesis that chorioamnionitis promotes CLD and interacts with other risk factors for CLD, including mechanical ventilation and postnatal infection...
  28. ncbi request reprint Perinatal infection, fetal inflammatory response, white matter damage, and cognitive limitations in children born preterm
    Olaf Dammann
    Neuroepidemiology Unit, Department of Neurology, Children s Hospital, Boston, Massachusetts 02115, USA
    Ment Retard Dev Disabil Res Rev 8:46-50. 2002
    ..We conclude that the relationship between antenatal infection and cognitive limitations deserves much further attention by researchers interested in the prevention of this undesirable outcome of prematurity...
  29. pmc An algorithm for identifying and classifying cerebral palsy in young children
    Karl C K Kuban
    Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, MA, USA
    J Pediatr 153:466-72. 2008
    ....
  30. ncbi request reprint The adaptive immune response in neonatal cerebral white matter damage
    Alan Leviton
    Neuroepidemiology Unit, Children s Hospital Boston, 1 Autumn Street, Boston, MA 02215 5349, USA
    Ann Neurol 58:821-8. 2005
    ..These include specific recognition of bacterial antigens, specific recognition of autoantigens, polyclonal activation by Toll-like receptors, and bystander activation by cytokines...
  31. ncbi request reprint Association between maternal serum ionized magnesium levels at delivery and neonatal intraventricular hemorrhage
    Robert Mittendorf
    Department of Obstetrics and Gynecology, Loyola University Medical Center, Maywood, Illinois 60153, USA
    J Pediatr 140:540-6. 2002
    ..To determine whether magnesium sulfate (MgSO(4)) exposure is associated with a reduced risk for neonatal intraventricular hemorrhage (IVH)...
  32. ncbi request reprint NEOBRAIN--an EU-funded project committed to protect the newborn brain
    Olaf Dammann
    Neonatology 92:217-8. 2007
  33. pmc Neuregulin-1: a potential endogenous protector in perinatal brain white matter damage
    Olaf Dammann
    Division of Newborn Medicine, Department of Pediatrics, Tufts New England Medical Center, Boston, Mass, USA
    Neonatology 93:182-7. 2008
    ..We outline how NRG-1 might be involved in perinatal brain damage pathomechanisms and suggest that NRG-1 might be one target for intervention...
  34. ncbi request reprint Neurological sequelae in in-vitro fertilisation babies
    Alan Leviton
    Lancet 360:718; author reply 719. 2002
  35. ncbi request reprint Biomarker epidemiology of cerebral palsy
    Olaf Dammann
    Ann Neurol 55:158-61. 2004
  36. ncbi request reprint Happiness reconsidered in children with cerebral palsy
    Olaf Dammann
    Department of Pediatrics, Tufts New England Medical Center, Boston, MA, USA
    Lancet 369:2137-8. 2007
  37. ncbi request reprint Anti-inflammatory and immunomodulatory strategies to protect the perinatal brain
    Adam J Wolfberg
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Tufts New England Medical Center, Boston, MA, USA
    Semin Fetal Neonatal Med 12:296-302. 2007
    ..Further research on the possible neuroprotective roles of existing medications and substances is necessary...
  38. ncbi request reprint Magnetic resonance and ultrasound brain imaging in preterm infants
    T MICHAEL O'SHEA
    Department of Pediatrics, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Early Hum Dev 81:263-71. 2005
    ..In this review we describe how well findings from these two imaging modalities agree with histology findings and neuro-developmental outcome. In addition, we discuss studies comparing ultrasound and magnetic resonance imaging findings...
  39. ncbi request reprint Incidence and clinical presentation of invasive neonatal group B streptococcal infections in Germany
    Kirsten Fluegge
    Department of Pediatrics and Adolescent Medicine, University Hospital Freiburg, Freiburg, Germany
    Pediatrics 117:e1139-45. 2006
    ..So far, there have been no published data on the incidence, morbidity, and mortality of invasive neonatal group B Streptococcus infections in Germany...
  40. ncbi request reprint Preconditioning and the developing brain
    Henrik Hagberg
    Department of Obstetrics and Gynecology, Institute of Women s and Children s Health, Goteborg University, Goteborg, Sweden
    Semin Perinatol 28:389-95. 2004
    ..Preconditioning of the brain or induction of tolerance of the immune system might be utilized in the future to decrease CNS vulnerability and the occurrence of perinatal brain injury...
  41. ncbi request reprint The wealth of information conveyed by gestational age
    Alan Leviton
    Children s Hospital and Department of Neurology, Harvard Medical School, Boston, MA 02115, USA
    J Pediatr 146:123-7. 2005
  42. ncbi request reprint Periventricular leukomalacia might not specifically affect cortical magnetoencephalographic response to biological motion
    Olaf Dammann
    Ann Neurol 60:269; author reply 269-70. 2006
  43. ncbi request reprint Neuroimaging and the prediction of outcomes in preterm infants
    Olaf Dammann
    N Engl J Med 355:727-9. 2006
  44. ncbi request reprint Antimicrobial resistance in Escherichia coli sepsis
    Olaf Dammann
    Pediatr Infect Dis J 23:978-9; author reply 979-80. 2004
  45. ncbi request reprint Impact of motor skills on cognitive test results in very-low-birthweight children
    Heike Losch
    Neuroepidemiology Unit, Department of Neurology, Children s Hospital, Harvard Medical School, Boston, MA, USA
    J Child Neurol 19:318-22. 2004
    ..Future studies need to evaluate whether factor scores only for cognitive but not motor abilities might be useful outcome variables...
  46. ncbi request reprint Risk of cranial ultrasound abnormalities in very-low-birth-weight infants conceived with assisted reproductive techniques
    Jane E Stewart
    Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    J Perinatol 22:37-45. 2002
    ....
  47. pmc Neonatal cranial ultrasound lesions and developmental delays at 2 years of age among extremely low gestational age children
    T MICHAEL O'SHEA
    Wake Forest University Health Sciences, Department of Pediatrics, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Pediatrics 122:e662-9. 2008
    ..Studies of the relationship between ultrasound images from preterm newborns and developmental delay most often are based on small samples defined by birth weight and exclude infants not testable with standardized assessments...