Thomas Becker

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. pmc A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma
    Andreas A Schnitzbauer
    University Hospital Regensburg, Department of Surgery, Regensburg, Germany
    BMC Cancer 10:190. 2010
  2. ncbi [Surgical treatment for hilar cholangiocarcinoma (Klatskin's tumor)]
    T Becker
    Klinik für Viszeral und Transplantationschirurgie, Zentrum Chirurgie der Medizinischen Hochschule Hannover
    Zentralbl Chir 128:928-35. 2003
  3. ncbi Pancreas transplantation with histidine-tryptophan-ketoglutarate (HTK) solution and University of Wisconsin (UW) solution: is there a difference?
    Thomas Becker
    Department of General, Visceral, and Transplant Surgery, Medical School of Hannover, Hannover, Germany
    JOP 8:304-11. 2007
  4. ncbi Paediatric kidney transplantation in small children-- a single centre experience
    Thomas Becker
    Department of General, Visceral and Transplant Surgery, Hannover Medical School, Germany
    Transpl Int 19:197-202. 2006
  5. doi Induction of heme oxygenase-1 improves the survival of pancreas grafts by prevention of pancreatitis after transplantation
    Thomas Becker
    Department of General, Visceral, and Transplant Surgery, Hannover Medical School, Hannover, Germany
    Transplantation 84:1644-55. 2007
  6. ncbi Results of combined and sequential liver-kidney transplantation
    Gulcin Demirci
    Klinik fuer Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover, Hannover, Germany
    Liver Transpl 9:1067-78. 2003
  7. ncbi Platelet P-selectin and GPIIb/IIIa expression after liver transplantation and resection
    Thomas Becker
    Department of Visceral and Transplant Surgery, Hanover Medical School, Carl Neuberg Strasse 1, 30625 Hanover, Germany
    Transpl Int 17:442-8. 2004
  8. ncbi The Donor-Risk-Index, ECD-Score and D-MELD-Score all fail to predict short-term outcome after liver transplantation with acceptable sensitivity and specificity
    Harald Schrem
    General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany
    Ann Transplant 17:5-13. 2012
  9. doi Value of the SOFA score as a predictive model for short-term survival in high-risk liver transplant recipients with a pre-transplant labMELD score ≥ 30
    Harald Schrem
    Department of General, Visceral and Transplantation Surgery, Medizinische Hochschule Hannover, Hannover, Germany
    Langenbecks Arch Surg 397:717-26. 2012
  10. doi Association of high anti-donor alloreactivity and low frequency of FoxP3-expressing cells prior to kidney transplantation with acute graft rejection
    Florian W R Vondran
    Transplant Laboratory, Department of General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany
    Clin Transplant 25:905-14. 2011

Detail Information

Publications112 found, 100 shown here

  1. pmc A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma
    Andreas A Schnitzbauer
    University Hospital Regensburg, Department of Surgery, Regensburg, Germany
    BMC Cancer 10:190. 2010
    ..Therefore, we designed a prospective RCT to determine if the mTOR inhibitor sirolimus can improve hepatocellular carcinoma (HCC)-free patient survival in liver transplant (LT) recipients with a pre-transplant diagnosis of HCC...
  2. ncbi [Surgical treatment for hilar cholangiocarcinoma (Klatskin's tumor)]
    T Becker
    Klinik für Viszeral und Transplantationschirurgie, Zentrum Chirurgie der Medizinischen Hochschule Hannover
    Zentralbl Chir 128:928-35. 2003
    ..Palliative treatment with additional radio- or photodynamic therapy may be considered in individual cases...
  3. ncbi Pancreas transplantation with histidine-tryptophan-ketoglutarate (HTK) solution and University of Wisconsin (UW) solution: is there a difference?
    Thomas Becker
    Department of General, Visceral, and Transplant Surgery, Medical School of Hannover, Hannover, Germany
    JOP 8:304-11. 2007
    ..Experience with histidine-tryptophan-ketoglutarate (HTK) is still limited whereas University of Wisconsin (UW) solution is currently the preferred perfusate worldwide...
  4. ncbi Paediatric kidney transplantation in small children-- a single centre experience
    Thomas Becker
    Department of General, Visceral and Transplant Surgery, Hannover Medical School, Germany
    Transpl Int 19:197-202. 2006
    ..Paediatric KTx is the treatment of choice even in very small children. Living donor KTx is the preferable donor source in terms of primary graft function and timing to transplantation...
  5. doi Induction of heme oxygenase-1 improves the survival of pancreas grafts by prevention of pancreatitis after transplantation
    Thomas Becker
    Department of General, Visceral, and Transplant Surgery, Hannover Medical School, Hannover, Germany
    Transplantation 84:1644-55. 2007
    ..Ischemia/reperfusion (I/R) injury after pancreas transplantation might result in graft pancreatitis. The role of heme oxygenase-1 (HO-1) in pancreas transplantation and prevention of graft pancreatitis is unknown...
  6. ncbi Results of combined and sequential liver-kidney transplantation
    Gulcin Demirci
    Klinik fuer Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover, Hannover, Germany
    Liver Transpl 9:1067-78. 2003
    ..When liver transplantation was performed early and electively before substantial worsening, combined L-KTx is a safe procedure offering excellent long-term palliation...
  7. ncbi Platelet P-selectin and GPIIb/IIIa expression after liver transplantation and resection
    Thomas Becker
    Department of Visceral and Transplant Surgery, Hanover Medical School, Carl Neuberg Strasse 1, 30625 Hanover, Germany
    Transpl Int 17:442-8. 2004
    ..After liver transplantation, increasing serum TPO levels, which indicated a recovering graft function, resulted in rising peripheral platelet counts...
  8. ncbi The Donor-Risk-Index, ECD-Score and D-MELD-Score all fail to predict short-term outcome after liver transplantation with acceptable sensitivity and specificity
    Harald Schrem
    General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany
    Ann Transplant 17:5-13. 2012
    ..This study investigates the ability of the Donor-Risk-Index (DRI), the Extended-Criteria-Donor-Score (ECD-score) and the D-MELD-score to predict early outcome after liver transplantation...
  9. doi Value of the SOFA score as a predictive model for short-term survival in high-risk liver transplant recipients with a pre-transplant labMELD score ≥ 30
    Harald Schrem
    Department of General, Visceral and Transplantation Surgery, Medizinische Hochschule Hannover, Hannover, Germany
    Langenbecks Arch Surg 397:717-26. 2012
    ..We analysed the value of the SOFA score for the prediction of short-term survival after liver transplantation in high-risk liver transplant recipients with a labMELD score ≥30...
  10. doi Association of high anti-donor alloreactivity and low frequency of FoxP3-expressing cells prior to kidney transplantation with acute graft rejection
    Florian W R Vondran
    Transplant Laboratory, Department of General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany
    Clin Transplant 25:905-14. 2011
    ..In conclusion, pre-transplant anti-donor alloreactivity and FoxP3 expression within the CD4(+) CD25(+) CD127(low) subpopulation might prove useful to further define the patient's risk for AR...
  11. doi The introduction of MELD-based organ allocation impacts 3-month survival after liver transplantation by influencing pretransplant patient characteristics
    Tobias J Weismüller
    Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
    Transpl Int 22:970-8. 2009
    ..Reduced 3-month survival was associated with longer surgery duration, higher creatinine and urea likely reflecting higher recipient morbidity. Survival probability should be incorporated into MELD-based graft allocation...
  12. ncbi Living kidney donors >60 years of age: is it acceptable for the donor and the recipient?
    Michael Neipp
    Klinik fuer Allgemein, Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover, Hannover, Germany
    Transpl Int 19:213-7. 2006
    ..Thereafter, values were comparable for both groups. As excellent results are achievable using living donors >60 years, we suggest that age should no longer be considered as a contra-indication for living donation...
  13. ncbi Value of the preoperative SOFT-score, P-SOFT-score, SALT-score and labMELD-score for the prediction of short-term patient and graft survival of high-risk liver transplant recipients with a pre-transplant labMELD-score ≥30
    Benedikt Reichert
    General, Visceral and Transplantation Surgery, Hanover Medical School, Germany
    Ann Transplant 17:11-7. 2012
    ..We analysed the value of these scores for the prediction of short-term survival in high-risk liver transplant recipients with a labMELD-score ≥30...
  14. doi The L-arginine/NO pathway in end-stage liver disease and during orthotopic liver and kidney transplantation: biological and analytical ramifications
    Thomas Becker
    Department of Visceral and Transplant Surgery, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Nitric Oxide 20:61-7. 2009
    ..The importance of analytical chemistry in this area of research is also discussed in this article...
  15. doi Gene expression profiling in hepatocellular carcinoma: upregulation of genes in amplified chromosome regions
    Britta Skawran
    Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
    Mod Pathol 21:505-16. 2008
    ..Expression analysis and comparative genomic hybridisation identified an upregulation of genes in amplified regions of 1q. These results may serve to further narrow down the number of candidate driver genes in hepatocarcinogenesis...
  16. doi Loss of 13q is associated with genes involved in cell cycle and proliferation in dedifferentiated hepatocellular carcinoma
    Britta Skawran
    Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
    Mod Pathol 21:1479-89. 2008
    ....
  17. doi Living donor liver transplantation: effect of the type of liver graft donation on donor mortality and morbidity
    Lampros Kousoulas
    Department of General, Visceral and Transplant Surgery, Hanover Medical School, Hanover, Germany
    Transpl Int 24:251-8. 2011
    ....
  18. ncbi Quality of life following living donor nephrectomy comparing classical flank incision and anterior vertical mini-incision
    Steffan Jackobs
    Klinik für Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover, Carl Neuberg Str 1, 30625 Hannover, Germany
    World J Urol 23:343-8. 2005
    ..Open-donor nephrectomy is a safe and cost-effective procedure. Introduction of the here-described MIDN has led to comparable or even improved results compared to LDN...
  19. doi Decreased frequency of peripheral CD4(+) CD161(+) Th(17) -precursor cells in kidney transplant recipients on long-term therapy with Belatacept
    Florian Wolfgang Rudolf Vondran
    Transplant Laboratory, Department of General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany
    Transpl Int 25:455-63. 2012
    ..The distinct effects of Belatacept on Th(17) -immunity might prove beneficial for the long-term outcome following kidney transplantation...
  20. ncbi The role of portal vein clamping for cytokine release and neutrophils activity during liver resection and transplant
    Arthur Studzinski
    Department of Anaesthesiology, Hannover Medical School, 30625 Hannover, Germany
    Exp Clin Transplant 6:254-60. 2008
    ..We argue that temporary vascular clamping of the hepatic pedicle during major hepatic surgery is a potential stimulus for an excessive release of cytokines and the activity of neutrophils...
  21. ncbi Prediction of survival after liver transplantation by pre-transplant parameters
    Tobias J Weismüller
    Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
    Scand J Gastroenterol 43:736-46. 2008
    ..A prediction of outcome would improve preoperative patient selection and management...
  22. ncbi Anti-parietal cell autoantibodies (PCA) in primary biliary cirrhosis: a putative marker for recurrence after orthotopic liver transplantation?
    Sandra Ciesek
    Department of Gastroenterology, Hepatology and Endocrinology, Medical School, Hannover, Germany
    Ann Hepatol 9:181-5. 2010
    ..Aim of this analysis was to identify serological parameters associated with recurrent PBC...
  23. doi Indications for and outcomes after combined lung and liver transplantation: a single-center experience on 13 consecutive cases
    Gerrit Grannas
    Department of General, Visceral and Transplant Surgery, Hannover Medical School, Hannover, Germany
    Transplantation 85:524-31. 2008
    ..For several reasons, Lu-LTx is performed in few centers and information about the technical issues, posttransplant management and long-term outcomes associated with this procedure is limited...
  24. doi Dependence of platelet function on underlying liver disease in orthotopic liver transplantation
    Björn Jüttner
    Department of Anesthesiology, Hannover Medical School, Carl Neuberg Strasse 1, Hannover, Germany
    Thromb Res 124:433-8. 2009
    ..The purpose of the present study was to explore the platelet function during the perioperative period of orthotopic liver transplantation (OLT) due to the underlying liver disease...
  25. ncbi Extended right liver grafts obtained by an ex situ split can be used safely for primary and secondary transplantation with acceptable biliary morbidity
    Atsushi Takebe
    Department of General, Visceral, and Transplantation Surgery, Medizinische Hochschule Hannover, Hannover, Germany
    Liver Transpl 15:730-7. 2009
    ..The significantly longer cold ischemic time in the SLT group indicates the potential for improved results and should thus be considered in the design of allocation policies...
  26. ncbi Reduced P-selectin expression on circulating platelets after prolonged cold preservation in renal transplantation
    Dirk Scheinichen
    Department of Anaesthesiology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Clin Transplant 17:444-50. 2003
    ..Reduced expression of P-selectin on circulating platelets may be an indicator of I/R injury after prolonged kidney graft preservation...
  27. doi Health-related quality of life in adult transplant recipients more than 15 years after orthotopic liver transplantation
    Lampros Kousoulas
    Department of General, Visceral and Transplant Surgery, Hanover Medical School, Hanover, Germany
    Transpl Int 21:1052-8. 2008
    ..More than 15 years after OLT, long-term survivors present a poor HRQOL comparable to the reference population. Occupational rehabilitation was the only factor shown to positively influence long-term HRQOL...
  28. ncbi Blood transfers infectious immunologic tolerance in MHC-incompatible heart transplantation in rats
    Hueseyin Bektas
    Visceral and Transplantation Surgery, Medizinische Hochschule Hannover, Hannover, Germany
    J Heart Lung Transplant 24:614-7. 2005
    ..We conclude that in rat heart transplantation, the transfer of immunologic tolerance can be enhanced by transfusing blood from tolerant animals to naive animals before transplantation across MHC barriers...
  29. ncbi Outcome and quality of life in patients with polycystic liver disease after liver or combined liver-kidney transplantation
    Gabriele I Kirchner
    Gastroenterology, Hepatology, and Endocrinology, Medical School of Hannover, Hannover, Germany
    Liver Transpl 12:1268-77. 2006
    ..In conclusion, patients with advanced polycystic liver or polycystic liver-kidney disease have an excellent survival rate and an improved quality of life after liver or combined liver-kidney transplantation...
  30. ncbi Living donor nephrectomy: flank incision versus anterior vertical mini-incision
    Michael Neipp
    Department of Transplantation, Medizinische Hochschule Hannover, Hannover, Germany
    Transplantation 78:1356-61. 2004
    ..Currently, many centers perform laparoscopic donor nephrectomy (DN). We studied the outcome of donors and recipients following open DN using either flank incision (ODN) or mini-incision (MIDN)...
  31. doi Impact of Basiliximab on regulatory T-cells early after kidney transplantation: down-regulation of CD25 by receptor modulation
    Florian Wolfgang Rudolf Vondran
    Transplant Laboratory, Department of General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany
    Transpl Int 23:514-23. 2010
    ..Thus, it is unlikely that Basiliximab treatment negatively influences strategies involving T(regs) to promote tolerance after organ transplantation...
  32. ncbi Epigenetic defects of hepatocellular carcinoma are already found in non-neoplastic liver cells from patients with hereditary haemochromatosis
    Ulrich Lehmann
    Institute of Pathology, Medizinische Hochschule Hannover, Germany
    Hum Mol Genet 16:1335-42. 2007
    ..Thus, changes in DNA methylation patterns are an early event preceding morphological alterations of malignant transformation and represent promising targets for early detection...
  33. ncbi Liver transplantation using organs from donors older than 60 years
    Michael Neipp
    Clinic for Transplantation Surgery, Medical University of Hanover, Carl Neuberg Strasse, 30625 Hanover, Germany
    Transpl Int 17:416-23. 2004
    ..The frequency of vascular complications and cholestasis syndrome is not increased...
  34. doi Measurement and diagnostic use of hepatic cytochrome P450 metabolism of oleic acid in liver disease
    Thomas Thum
    Institute for Molecular and Translational Therapeutic Strategies, Hannover Medical School, Hannover, Germany
    Liver Int 30:1181-8. 2010
    ..Furthermore, the extent of the oleic acid oxidation product cis-9,10-epoxyoctadecanoic acid (cis-EODA) in humans and its plasma levels in patients with impaired liver function are not known...
  35. doi Losses of chromosome arms 4q, 8p, 13q and gain of 8q are correlated with increasing chromosomal instability in hepatocellular carcinoma
    Sabine Hertz
    Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
    Pathobiology 75:312-22. 2008
    ..Therefore, we examined whether there was a correlation between structural and numerical aberrations of chromosomal instability in HCC...
  36. doi High intrahepatic HHV-6 virus loads but neither CMV nor EBV are associated with decreased graft survival after diagnosis of graft hepatitis
    Sven Pischke
    Department for Gastroenterology, Hannover Medical School, Hannover, Germany
    J Hepatol 56:1063-9. 2012
    ..In liver transplant recipients with graft hepatitis, the relevance of herpesviruses is not well defined...
  37. doi Laparoscopic versus conventional Kasai portoenterostomy does not facilitate subsequent liver transplantation in infants with biliary atresia
    Christina Oetzmann von Sochaczewski
    Department of Pediatric Surgery, Hannover Medical School, Hannover, Germany
    J Laparoendosc Adv Surg Tech A 22:408-11. 2012
    ..It has been reported that reduced internal scarring and fewer adhesions could facilitate the subsequent liver transplantation and thus represent a potential advantage of the laparoscopic technique...
  38. doi High-dose erythropoietin has no effect on short- or long-term graft function following deceased donor kidney transplantation
    Carsten Hafer
    Department of Internal Medicine, Hannover Medical School, Hannover, Germany
    Kidney Int 81:314-20. 2012
    ..Thus, treatment with high-dose rHuEPO after kidney transplantation, although well tolerated, had no effect on long-term graft function or histology...
  39. ncbi Accidental transplantation of a kidney with a cystic renal cell carcinoma following living donation: management and 1 yr follow-up
    Michael Neipp
    Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover, Germany
    Clin Transplant 20:147-50. 2006
    ..Our policy to obtain the kidney presenting anatomical variations proved to be beneficial for the donor. In case of transmission of cancer partial resection preserving graft function might be justified...
  40. ncbi Quality of life in adult transplant recipients more than 15 years after kidney transplantation
    Michael Neipp
    Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover, Hannover, Germany
    Transplantation 81:1640-4. 2006
    ..With continuously rising survival rates following renal transplantation, health-related quality of life (HQOL) of long-term transplant survivors becomes increasingly important...
  41. ncbi Assessment of differentiation and progression of hepatic tumors using array-based comparative genomic hybridization
    Doris Steinemann
    Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
    Clin Gastroenterol Hepatol 4:1283-91. 2006
    ....
  42. doi Reduced post-operative neutrophil activation in liver transplant recipients suffering from post-hepatitic cirrhosis
    Björn Jüttner
    Departments of Anesthesiology, Hannover Medical School, Hannover, Germany
    Clin Transplant 23:921-9. 2009
    ..This study was designed to investigate whether neutrophil function is immediately affected by liver transplantation...
  43. doi Patient outcomes in two steroid-free regimens using tacrolimus monotherapy after daclizumab induction and tacrolimus with mycophenolate mofetil in liver transplantation
    Thomas Becker
    Medizinische Hochschule Hannover, Germany
    Transplantation 86:1689-94. 2008
    ..Maintaining effective immunoprophylaxis while minimizing the negative consequences of steroid therapy could be a key factor in improving clinical outcomes...
  44. doi Incidence and outcome of abdominal surgical interventions following lung transplantation--a single center experience
    Kai Timrott
    Department of General, Visceral and Transplantation Surgery, Hannover Medical School, Carl Neuberg Str 1, 30625, Hannover, Germany
    Langenbecks Arch Surg 396:1231-7. 2011
    ..Abdominal complications after lung transplantation (LuTx) are associated with a high mortality risk. Aim of the present study was to analyse frequency and outcome of abdominal interventions following LuTx...
  45. doi Gender-incompatible liver transplantation is not a risk factor for patient survival
    Frank Lehner
    Department of General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany
    Liver Int 29:196-202. 2009
    ..We therefore investigated patient survival as well as metabolism of steroids to identify possible causes of improved graft survival in gender-mismatched OLT...
  46. pmc The novel immunosuppressive protein kinase C inhibitor sotrastaurin has no pro-viral effects on the replication cycle of hepatitis B or C virus
    Thomas von Hahn
    Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
    PLoS ONE 6:e24142. 2011
    ..These data support the evaluation of sotrastaurin in HBV and/or HCV infected transplant recipients...
  47. ncbi The value of reoperative procedures after unusual reconstructions in the gastrointestinal tract associated with substantial morbidity
    Hueseyin Bektas
    Klinik für Viszeral und Transplantationschirurgie, Medizinische Hochschule, Hannover, Germany
    J Gastrointest Surg 10:111-22. 2006
    ..Compliance with well-established standard reconstructive procedures is of elementary importance in the gastrointestinal tract. Operative correction of uncommon reconstructions associated with morbidity is usually indicated...
  48. pmc Evaluation of living liver donors using contrast enhanced multidetector CT - The radiologists impact on donor selection
    Kristina Imeen Ringe
    Department of Diagnostic and Interventional Radiology, Hannover Medical School, Carl Neuberg Str, 1, 30625, Hannover, Germany
    BMC Med Imaging 12:21. 2012
    ..Computed tomography (CT) has proven to be an important tool in the process of donor evaluation. The purpose of this study was to evaluate the significance of CT in the donor selection process...
  49. pmc Basiliximab induction therapy in kidney transplantation: benefits for long term allograft function after 10 years?
    Martina Koch
    Klinik fuer Allgemein, Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover, Hannover, Germany
    Biologics 3:51-6. 2009
    ..In this small study patient and graft survival was equivalent 10 years after transplantation comparing basiliximab induction therapy and placebo...
  50. doi Persistence of occult hepatitis B after removal of the hepatitis B virus-infected liver
    Sandra Ciesek
    Department of Gastroenterology, Hepatology, and Endocrinology, Hannover Medical School, Hannover, Germany
    J Infect Dis 197:355-60. 2008
    ..Thus, these data indicate that a long-term extrahepatic HBV reservoir exists, which is relevant not only for liver transplantation but also for other types of transplantations, including bone marrow grafting...
  51. ncbi Benign cystic mesothelioma of the liver
    Peer Flemming
    Institut fuer Pathologie, Medizinische Hochschule Hannover, Germany
    Am J Surg Pathol 26:1523-7. 2002
  52. ncbi Biliary atresia research is crossing national and interdisciplinary borderlines by the European Biliary Atresia Registry (EBAR)
    Claus Petersen
    Department of Paediatric Surgery, Medical School Hannover, Hannover, Germany
    Acta Paediatr 94:526-7. 2005
    ..The objectives of this association are to create clinical and basic research studies, which are based on existing registries in Europe...
  53. ncbi Infiltrates in protocol biopsies from renal allografts
    M Mengel
    Institut fuer Pathologie, Medizinische Hochschule Hannover, Germany
    Am J Transplant 7:356-65. 2007
    ..As detected by sequential biopsies, persistence of any inflammation including those infiltrates currently not considered by the Banff classification should be regarded as a morphological correlate of ongoing allograft damage...
  54. doi European biliary atresia registries: summary of a symposium
    C Petersen
    Department of Pediatric Surgery, Medical School Hannover, Hannover, Germany
    Eur J Pediatr Surg 18:111-6. 2008
    ....
  55. doi Course and relevance of arteriovenous fistulas after renal transplant biopsies
    A Schwarz
    Department of Nephrology, Hannover Medical School, Hannover, Germany
    Am J Transplant 8:826-31. 2008
    ..There is no established test predicting which patient will benefit from embolization; however, Doppler-determined resistive index may help in this regard...
  56. doi [Long-term results after liver transplantation]
    H Schrem
    Allgemein, Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30625 Hannover
    Chirurg 79:121-9. 2008
    ..4% for PSC, 78.5% for biliary atresia, 70% for acute liver failure, 69.1% for HBV-related cirrhosis, 61.3% for hepatocellular carcinoma, and 56% for HCV-related cirrhosis...
  57. ncbi [Congenital absence of the portal vein (CAPV). Two cases of Abernethy malformation type 1 and review of the literature]
    K Ringe
    Abteilung Diagnostische Radiologie, Medizinische Hochschule Hannover, Carl Neuberg Strabe 1, 30625, Hannover
    Radiologe 48:493-502. 2008
    ..We report two cases diagnosed with a type 1 shunt, hepatic encephalopathy, and associated liver tumors who underwent successful liver transplantation after having considered all therapeutic options...
  58. doi [Progress in immunosuppression]
    C P Strassburg
    Klinik fur Gastroenterologie, Hepatologie und Endokrinologie, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30625 Hannover
    Chirurg 79:149-56. 2008
    ..Novel drugs and strategies for the induction of tolerance are under development...
  59. ncbi [Late stage stenoses of bile ducts after iatrogenic bile duct injuries following cholecystectomy]
    H Bektas
    Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover
    Zentralbl Chir 132:523-8. 2007
    ..For the attending physician therapy and management of these injuries are a challenge. Inadequate and delayed treatment can lead to stenoses at a late stage, which can necessitate further surgical intervention...
  60. ncbi Differentiation of liver cell adenomas from well-differentiated hepatocellular carcinomas by comparative genomic hybridization
    L Wilkens
    Institute of Pathology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    J Pathol 193:476-82. 2001
    ..CGH is therefore helpful in distinguishing between LCA and well-differentiated HCC. Detection of one or more of the six most frequent aberrations in HCC supports the diagnosis of carcinoma and makes LCA unlikely...
  61. ncbi [Neuroendocrine tumors of the stomach. Surgery therapy and prognosis]
    H Bektas
    Klinik für Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30625 Hannover
    Chirurg 73:331-5. 2002
    ..A local excision was performed on one patient with type I tumor. After a mean follow-up of 8 years, 5 of 7 patients are alive without recurrence...
  62. ncbi [Comparison between treatment results for gastric cancer in younger and elderly patients]
    P Piso
    Klinik für Viszeral und Transplantationschirurgie, Zentrum Chirurgie, Medizinischen Hochschule Hannover, Germany
    Zentralbl Chir 127:270-4. 2002
    ..Younger patients are frequently diagnosed with advanced tumor stages with a poor prognosis although literature data on this issue are controversial...
  63. ncbi [Angiodysplasia of the colon combined with portal hypertension and recurrent gastrointestinal bleeding]
    F Lehner
    Klinik für Viszeral und Transplantationschirurgie Hannover
    Zentralbl Chir 128:1093-6. 2003
    ..In this regard we discuss diagnosis, therapy and prognosis of this disease...
  64. ncbi [Organ transplantation in endocrinology. Islet cells and pancreas]
    E Jaeckel
    Abteilung Gastroenterologie, Hepatologie, Endokrinologie, Medizinische Hochschule Hannover
    Internist (Berl) 45:1268-80. 2004
    ..New developments in protecting transplanted islets and in the induction of donor-specific tolerance could increase the indication to perform the procedure. Therefore alternative sources of beta-cells have to be identified...
  65. ncbi [Liver transplantation: deciding between need and donor allocation]
    C P Strassburg
    Abteilung für Gastroenterologie, Hepatologie und Endokrinologie, Medizinische Hochschule Hannover
    Internist (Berl) 45:1233-45. 2004
    ..Fair allocation and medical necessity therefore define the challenges surrounding the indications for liver transplantation...
  66. ncbi Common and epithelioid variants of hepatic angiomyolipoma exhibit clonal growth and share a distinctive immunophenotype
    P Flemming
    Institut fur Pathologie, Medizinische Hochschule Hannover, Hannover, Germany
    Hepatology 32:213-7. 2000
    ..The epithelioid subtype may give rise to intrahepatic metastasis...
  67. doi [Liver resection for non-colorectal, non-neuroendocrine liver metastases--is hepatic resection justified as part of the oncosurgical treatment?]
    F Lehner
    Medizinsche Hochschule Hannover, Allgemein, Viszeral und Transplantationschirurgie, Carl Neuberg Strasse 1, Hannover, Germany
    Zentralbl Chir 134:430-6. 2009
    ..The aim of the present study was to determine the utility of liver resection in the long-term outcome of patients with non-colorectal, non-neuroendocrine liver metastases and to define prognostic factors predicting long-term survivors...
  68. pmc Diagnostic impact of fluorescence in situ hybridization in the differentiation of hepatocellular adenoma and well-differentiated hepatocellular carcinoma
    L Wilkens
    Department of Pathology, Hanover Medical School, Hanover, Germany
    J Mol Diagn 3:68-73. 2001
    ..Thus, FISH for chromosomes 1 and 8, extended by probes for chromosomes 6, 7 and X, represents a promising approach toward a more accurate differentiation between hepatocellular adenoma and carcinoma...
  69. doi [Predictive parameters in children with biliary atresia]
    J Leonhardt
    Klinik für Kinderchirurgie, Medizinische Hochschule, Hannover, Germany
    Chirurg 80:628-33. 2009
    ..In conclusion our data demonstrate that a lack of predictive factors must prevent primary liver transplantation in BA patients...
  70. ncbi Superior long-term graft function and better growth of grafts in children receiving kidneys from paediatric compared with adult donors
    L Pape
    Department of Pediatric Nephrology, Visceral and Transplant Surgery, Medical School of Hannover, Germany
    Nephrol Dial Transplant 21:2596-600. 2006
    ..On the other hand, studies have shown that kidneys of adult donors transplanted into children down-regulate filtration after transplantation and may not increase their function to the need of the growing child...
  71. doi Transsplenic endovascular therapy of portal vein stenosis and subsequent complete portal vein thrombosis in a 2-year-old child
    Harald Bertram
    Department of Pediatric Cardiology and Pediatric Intensive Care, Hannover Medical School, Hannover, Germany
    J Vasc Interv Radiol 21:1760-4. 2010
    ..In selected patients, percutaneous transsplenic access to the portal vein circulation may be used for diagnostic and therapeutic interventions even in early childhood...
  72. ncbi Distinct methylation patterns of benign and malignant liver tumors revealed by quantitative methylation profiling
    Ulrich Lehmann
    Institute of Pathology, Institute of Cell and Molecular Pathology, and Department of Visceral and Transplantation Surgery, Medizinische Hochschule Hannover, Hanover, Germany
    Clin Cancer Res 11:3654-60. 2005
    ..A comparative quantitative methylation profiling of hepatocellular carcinoma and the most frequent benign liver tumor, hepatocellular adenoma, was set up for the identification of tumor-specific methylation patterns...
  73. ncbi Comparative genomic hybridization (CGH) and fluorescence in situ hybridization (FISH) in the diagnosis of hepatocellular carcinoma
    Ludwig Wilkens
    Department of Pathology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    J Hepatobiliary Pancreat Surg 9:304-11. 2002
    ..Whether molecular cytogenetic analysis can contribute to the differential diagnosis of HCC was recently investigated by our group...
  74. doi Fulminant hepatic failure due to chemotherapy-induced hepatitis B reactivation: role of rituximab
    M A Stange
    Department of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, Hannover, Germany
    Z Gastroenterol 48:258-63. 2010
    ..Pre-emptive antiviral treatments should be administered since delayed antiviral treatment is frequently unable to prevent liver failure...
  75. ncbi Successful outcome of acute graft-versus-host disease in a liver allograft recipient by withdrawal of immunosuppression
    F Lehner
    Klinik für Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover, Germany
    Transplantation 73:307-10. 2002
    ..Graft-versus-host disease (GVHD) after liver transplantation is uncommon, and the outcome is almost always fatal. Since 1987, about 30 cases have been described, and patient survival is mostly exceptional...
  76. doi Endoscopic endoluminal vacuum therapy in esophageal perforation
    Nils Heits
    Department of General Surgery, Visceral, Thoracic, Transplantation and Pediatric Surgery, University Hospital Schleswig Holstein, Kiel, Germany
    Ann Thorac Surg 97:1029-35. 2014
    ..Endoscopic vacuum therapy (EVT) is a new endoscopic treatment option, which is used to treat anastomotic leakages after rectal and esophageal resections. We report on 10 patients treated with EVT for esophageal perforation...
  77. doi Postoperative high-dose steroids do not improve mid-term survival with native liver in biliary atresia
    Claus Petersen
    Department of Pedatric Surgery, Hannover Medical School, Hannover, Germany
    Am J Gastroenterol 103:712-9. 2008
    ..The aim of this dosage finding study was to test the most promising corticosteroid protocol in a smaller but representative series, in order to optimize the settings of upcoming prospective and long-term multicenter studies...
  78. ncbi Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and disease
    Dimitrios Tsikas
    Institut fur Klinische Pharmakologie, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, D 30625 Hannover, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 851:229-39. 2007
    ..17+/-4.2) being insignificantly lower (P=0.46). Between urinary DMA and ADMA there was a positive correlation (R=0.6655, P<0.0001) in coronary artery disease, but no correlation (R=0.27339) was found in end-stage liver disease...
  79. ncbi Successful treatment of fibrosing cholestatic hepatitis using adefovir dipivoxil in a patient with cirrhosis and renal insufficiency
    Hans L Tillmann
    Department of Gastroenterology, Hepatology, and Endocrinology, Medizinische Hochschule Hannover, Hannover, Germany
    Liver Transpl 9:191-6. 2003
    ..Adefovir dipivoxil resulted in significant clinical improvement in this patient with hepatitis B virus-induced fibrosing cholestatic hepatitis, despite the presence of renal impairment and lamivudine resistance...
  80. ncbi Update on liver transplantation using cyclosporine
    H Schrem
    Department of Viszeral und Transplantationschirurgie, Medizinische Hochschule Hannover, Hannover, Germany
    Transplant Proc 36:2525-31. 2004
    ..The individualized orchestration of immunosuppression taking into account the underlying liver disease as well as other individual predispositions remains a future challenge...
  81. ncbi Liver transplantation for liver cirrhosis in cystic fibrosis
    E Pfister
    Division of Pediatric Gastroenterology and Hepatology, Department of Pediatrics, Children s Hospital, Hannover Medical School, Hannover, Germany
    Transplant Proc 34:2281-2. 2002
  82. ncbi Effects of cyclosporine on human dendritic cell subsets
    S Ciesek
    Department of Gastroenterology, Hepatology and Endocrinology, Medizinische Hochschule, Hannover, Germany
    Transplant Proc 37:20-4. 2005
    ..In conclusion, cyclosporine differentially alters function and phenotype of myeloid dendritic cells leading to a partially impaired capacity to stimulate allogenic and autologous T cells...
  83. ncbi Interleukin-2 receptor antagonist induction in modern immunosuppression regimens for renal transplant recipients
    Flavio Vincenti
    Transplant Service, University of California, San Francisco, San Francisco, USA
    Transpl Int 19:446-57. 2006
    ..IL-2RAs, uniquely, provide effective immunosuppression with similar tolerability to placebo...
  84. ncbi Elevated plasma and urine levels of ADMA and 15(S)-8-iso-PGF2alpha in end-stage liver disease
    Dimitrios Tsikas
    Hepatology 38:1063-4. 2003
  85. ncbi Ex vivo microvesicle formation after prolonged ischemia in renal transplantation
    Tobias Schuerholz
    Clinic of Anesthesiology and Intensive Care, Friedrich Schiller University, Erlanger Allee 101, D 07747 Jena, Germany
    Thromb Res 120:231-6. 2007
    ..We investigated ex vivo formation of microvesicles in kidney transplantation and the influence of cold graft storage on microvesicles...
  86. ncbi Satisfaction with mental health services among people with schizophrenia in five European sites: results from the EPSILON Study
    Mirella Ruggeri
    Department of Medicine and Public Health, Section of Psychiatry, University of Verona, Italy
    Schizophr Bull 29:229-45. 2003
    ....
  87. ncbi Surgical experience in splitting donor liver into left lateral and right extended lobes
    Ji Qi Yan
    Department of Surgery, Ruijin Hospital Affiliated to Shanghai Second Medical University, Shanghai 200025, China
    World J Gastroenterol 11:4220-4. 2005
    ..To outline the surgical experience with donor liver splitting in split liver transplantation...
  88. ncbi Factor solution of the BPRS-expanded version in schizophrenic outpatients living in five European countries
    Mirella Ruggeri
    Dipartimento di Medicina e Sanita Pubblica, Sezione di Psichiatria, e Psicologie Clinice, Universita di Verona, Ospedale Policlinico, Piazzale Scuro, 10, 37134 Verona, Italy
    Schizophr Res 75:107-17. 2005
    ..The expanded version of the Brief Psychiatric Rating Scale (BPRS-E) has improved the instrument's coverage and interrater reliability, but there is little knowledge on its subsyndromes...
  89. ncbi Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway
    Amaury Herpin
    Sars International Centre for Marine Molecular Biology, High Technology Centre, Bergen, Norway
    FEBS J 272:3424-40. 2005
    ....
  90. doi SF-36 scales, and simple sums of scales, were reliable quality-of-life summaries for patients with schizophrenia
    Morven Leese
    Health Services and Population Research Department, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    J Clin Epidemiol 61:588-96. 2008
    ..To examine the feasibility and reliability of the Medical Outcomes Study 36 Item Short Form Health Survey (SF-36) for patients with schizophrenia, focusing on the eight scales and various aggregate summary measures...
  91. ncbi The personal impact of schizophrenia in Europe
    Graham Thornicroft
    Section of Community Psychiatry, Health Services Research Department, Institute of Psychiatry, Kings College London, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 69:125-32. 2004
    ..Research, clinical practice and disability policy developments need to address a wider range of consequences of the disorder than symptoms alone...
  92. ncbi Needs for care of patients with schizophrenia and the consequences for their informal caregivers- results from the EPSILON multi centre study on schizophrenia
    Karin Meijer
    Department of Psychiatry, Academic Medical Centre Rm A3 254, 22700, 1100, DE Amsterdam, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 39:251-8. 2004
    ..In this study, we investigated whether needs for care of patients with schizophrenia are related to (negative) consequences for their informal caregivers...
  93. ncbi People with schizophrenia in five countries: conceptual similarities and intercultural differences in family caregiving
    Bob van Wijngaarden
    Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands
    Schizophr Bull 29:573-86. 2003
    ..As long as cultural bias cannot be ruled out, researchers are advised to compose their own national norm groups and use these as a local standard...
  94. pmc Prediction of the plant beta-barrel proteome: a case study of the chloroplast outer envelope
    Enrico Schleiff
    Botanisches Institut der Ludwig Maximilian Universität München, 80368 München, Germany
    Protein Sci 12:748-59. 2003
    ..In addition to the known components, four new proteins of the outer envelope membranes were identified in this study...
  95. ncbi Expression of protein zero is increased in lesioned axon pathways in the central nervous system of adult zebrafish
    Jörn Schweitzer
    Zentrum für Molekulare Neurobiologie, Universitat Hamburg, Hamburg, Germany
    Glia 41:301-17. 2003
    ..The glial upregulation of P0 mRNA expression after a lesion of the adult zebrafish CNS suggests roles for P0 in promoting axon regeneration and remyelination after injury...
  96. ncbi Comparing patterns and costs of schizophrenia care in five European countries: the EPSILON study. European Psychiatric Services: Inputs Linked to Outcome Domains and Needs
    Martin Knapp
    Department of Health Services Research, Institute of Psychiatry, King s College Medical School, London, UK
    Acta Psychiatr Scand 105:42-54. 2002
    ..To compare service utilization and cost profiles of people with schizophrenia living in Europe in order to understand differences in treatment and care costs...
  97. ncbi Hepatocyte transplantation in an acute liver failure due to mushroom poisoning
    Andrea Schneider
    Transplantation 82:1115-6. 2006
  98. ncbi Needs and quality of life among patients with schizophrenia in five European centres: what is the impact of global functioning scores?
    Thomas Becker
    Dept of Psychiatry II, University of Ulm, Ludwig Heilmeyer Strasse 2, 89312, Gunzburg, Germany
    Soc Psychiatry Psychiatr Epidemiol 40:628-34. 2005
    ....
  99. ncbi [Adjustment disorders--nosological state and treatment options]
    Markus Jager
    Klinik für Psychiatrie und Psychotherapie II der Universität Ulm, Bezirkskrankenhaus Günzburg
    Psychiatr Prax 35:219-25. 2008
    ..To provide an overview of empirical findings with regard to adjustment disorders...
  100. doi IPS in Europe: the EQOLISE trial
    Tom Burns
    Social Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
    Psychiatr Rehabil J 31:313-7. 2008
    ..Evidence of the effectiveness of IPS in these conditions, and its potential variation across them, would guide local policy and provide possible insights into its mechanism...
  101. ncbi Sex differences in the subjective tolerability of antipsychotic drugs
    Corrado Barbui
    Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
    J Clin Psychopharmacol 25:521-6. 2005
    ..Studies should no longer consider men and women as a homogeneous group, given that the subjective tolerability of antipsychotic drugs substantially differs between sexes...