Christina Allmeling

Summary

Affiliation: Hannover Medical School
Country: Germany

Publications

  1. doi request reprint Spider silk fibres in artificial nerve constructs promote peripheral nerve regeneration
    C Allmeling
    Department of Plastic, Hand and Reconstructive Surgery, Medical School Hannover, Hannover, Germany
    Cell Prolif 41:408-20. 2008
  2. ncbi request reprint Use of spider silk fibres as an innovative material in a biocompatible artificial nerve conduit
    Christina Allmeling
    Department of Plastic, Hand and Reconstructive Surgery, Medical School Hannover, Podbielskistr 380, D 30659 Hannover, Germany
    J Cell Mol Med 10:770-7. 2006
  3. pmc Artificial skin--culturing of different skin cell lines for generating an artificial skin substitute on cross-weaved spider silk fibres
    Hanna Wendt
    Department of Plastic, Hand, and Reconstructive Surgery, Medical School Hannover, Hannover, Germany
    PLoS ONE 6:e21833. 2011
  4. ncbi request reprint Biomechanics and biocompatibility of woven spider silk meshes during remodeling in a rodent fascia replacement model
    Franziska Schäfer-Nolte
    From the Department of Plastic, Hand and Reconstructive Surgery, Medical School Hannover, Hannover, Germany Dr Mirastschijski is now with Department of Plastic, Reconstructive and Aesthetic Surgery, Klinikum Bremen Mitte, University of Gottingen, Bremen Germany
    Ann Surg 259:781-92. 2014
  5. doi request reprint First investigation of spider silk as a braided microsurgical suture
    Joern W Kuhbier
    Department of Plastic, Hand, and Reconstructive Surgery, Medical School Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    J Biomed Mater Res B Appl Biomater 97:381-7. 2011
  6. pmc Spider silk constructs enhance axonal regeneration and remyelination in long nerve defects in sheep
    Christine Radtke
    Department of Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Hannover, Germany
    PLoS ONE 6:e16990. 2011
  7. doi request reprint AmbLOXe--an epidermal lipoxygenase of the Mexican axolotl in the context of amphibian regeneration and its impact on human wound closure in vitro
    Bjoern Menger
    Department of Plastic, Hand, and Reconstructive Surgery, Replantation and Burn Center of Lower Saxony, Laboratory of Experimental Plastic Surgery, Hannover Medical School, Hannover, Germany
    Ann Surg 253:410-8. 2011
  8. pmc Bundles of spider silk, braided into sutures, resist basic cyclic tests: potential use for flexor tendon repair
    Kathleen Hennecke
    Department of Plastic, Hand, and Reconstructive Surgery, Medical School Hannover, Hannover, Germany
    PLoS ONE 8:e61100. 2013
  9. pmc Interactions between spider silk and cells--NIH/3T3 fibroblasts seeded on miniature weaving frames
    Joern W Kuhbier
    Department of Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Hannover, Germany
    PLoS ONE 5:e12032. 2010
  10. doi request reprint The yeast two hybrid system in a screen for proteins interacting with axolotl (Ambystoma mexicanum) Msx1 during early limb regeneration
    Mehtap Abuqarn
    Departmen tof Plastic, Hand and Reconstructive Surgery, Medical School of Hannover, Podbielskistrasse 380, D 30659 Hannover, Germany
    Biochim Biophys Acta 1814:843-9. 2011

Collaborators

Detail Information

Publications19

  1. doi request reprint Spider silk fibres in artificial nerve constructs promote peripheral nerve regeneration
    C Allmeling
    Department of Plastic, Hand and Reconstructive Surgery, Medical School Hannover, Hannover, Germany
    Cell Prolif 41:408-20. 2008
    ..In our study, we describe the use of spider silk fibres as a new material in nerve tissue engineering, in a 20-mm sciatic nerve defect in rats...
  2. ncbi request reprint Use of spider silk fibres as an innovative material in a biocompatible artificial nerve conduit
    Christina Allmeling
    Department of Plastic, Hand and Reconstructive Surgery, Medical School Hannover, Podbielskistr 380, D 30659 Hannover, Germany
    J Cell Mol Med 10:770-7. 2006
    ..In conclusion, our results show that artificial nerve grafts can be constructed successfully from spider silk, acellularized veins and SC mixed with matrigel...
  3. pmc Artificial skin--culturing of different skin cell lines for generating an artificial skin substitute on cross-weaved spider silk fibres
    Hanna Wendt
    Department of Plastic, Hand, and Reconstructive Surgery, Medical School Hannover, Hannover, Germany
    PLoS ONE 6:e21833. 2011
    ..Additionally, it should degrade in an appropriate time period without releasing harmful substances, but not exert a pathological immune response. Spider dragline silk from Nephila spp meets these demands to a large extent...
  4. ncbi request reprint Biomechanics and biocompatibility of woven spider silk meshes during remodeling in a rodent fascia replacement model
    Franziska Schäfer-Nolte
    From the Department of Plastic, Hand and Reconstructive Surgery, Medical School Hannover, Hannover, Germany Dr Mirastschijski is now with Department of Plastic, Reconstructive and Aesthetic Surgery, Klinikum Bremen Mitte, University of Gottingen, Bremen Germany
    Ann Surg 259:781-92. 2014
    ..The aim of this study was to investigate biomechanical and immunogenic properties of spider silk meshes implanted as fascia replacement in a rat in vivo model...
  5. doi request reprint First investigation of spider silk as a braided microsurgical suture
    Joern W Kuhbier
    Department of Plastic, Hand, and Reconstructive Surgery, Medical School Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    J Biomed Mater Res B Appl Biomater 97:381-7. 2011
    ..With regards to the mechanical properties, these sutures were superior to nylon sutures. As spider silk displays high biocompatibility in nerve regeneration, its usage in microsurgical nerve repair should be considered...
  6. pmc Spider silk constructs enhance axonal regeneration and remyelination in long nerve defects in sheep
    Christine Radtke
    Department of Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Hannover, Germany
    PLoS ONE 6:e16990. 2011
    ..We describe the use of nerve constructs consisting of decellularized vein grafts filled with spider silk fibers as a guiding material to bridge a 6.0 cm tibial nerve defect in adult sheep...
  7. doi request reprint AmbLOXe--an epidermal lipoxygenase of the Mexican axolotl in the context of amphibian regeneration and its impact on human wound closure in vitro
    Bjoern Menger
    Department of Plastic, Hand, and Reconstructive Surgery, Replantation and Burn Center of Lower Saxony, Laboratory of Experimental Plastic Surgery, Hannover Medical School, Hannover, Germany
    Ann Surg 253:410-8. 2011
    ..In this study we identified an amphibian lipoxygenase and evaluated its impact on human cells in an in vitro wound model...
  8. pmc Bundles of spider silk, braided into sutures, resist basic cyclic tests: potential use for flexor tendon repair
    Kathleen Hennecke
    Department of Plastic, Hand, and Reconstructive Surgery, Medical School Hannover, Hannover, Germany
    PLoS ONE 8:e61100. 2013
    ..These results suggest that braided spider silk could be suitable for use as sutures in flexor tendon repair, providing similar tensile behaviour and improved fatigue properties compared with conventional suture materials...
  9. pmc Interactions between spider silk and cells--NIH/3T3 fibroblasts seeded on miniature weaving frames
    Joern W Kuhbier
    Department of Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Hannover, Germany
    PLoS ONE 5:e12032. 2010
    ..Not only does it own unique mechanical properties, its biocompatibility has been shown already in vivo. In our study, we used native spider dragline silk which is known as the strongest fibre in nature...
  10. doi request reprint The yeast two hybrid system in a screen for proteins interacting with axolotl (Ambystoma mexicanum) Msx1 during early limb regeneration
    Mehtap Abuqarn
    Departmen tof Plastic, Hand and Reconstructive Surgery, Medical School of Hannover, Podbielskistrasse 380, D 30659 Hannover, Germany
    Biochim Biophys Acta 1814:843-9. 2011
    ..It is the first time, that the yeast two hybrid system was adapted to the axolotl animal model and successfully used in a screen for proteins interacting with Msx1 in the context of amphibian limb regeneration...
  11. ncbi request reprint [In vitro fabrication of tendon substitutes using human mesenchymal stem cells and a collagen type I gel]
    S Kall
    Labor für experimentelle Plastische Chirurgie, Klinik für Plastische, Hand und Wiederherstellungschirurgie, Medizinische Hochschule Hannover
    Handchir Mikrochir Plast Chir 36:205-11. 2004
    ..In this study we investigated whether long tendon-like substitutes can be fabricated in vitro from human mesenchymal stem cells (MSCs) and a collagen type I gel when cultured under cyclic stretching conditions...
  12. doi request reprint A normothermic perfusion bioreactor to preserve viability of rat groin flaps extracorporally
    C Herold
    Department of Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Transplant Proc 41:4382-8. 2009
    ..This study was designed to evaluate the effect of permanent perfusion on fat flaps of the rat...
  13. doi request reprint Validation of differential gene expression in muscle engineered from rat groin adipose tissue by quantitative real-time PCR
    Yang An
    Department of Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Podbielskistr 380, 30659 Hannover, Germany
    Biochem Biophys Res Commun 421:736-42. 2012
    ..The use of β-2-microglobulin, RPL32 and RPL17 as internal standards may improve the accuracy of gene expression studies aimed at muscle tissue engineering under the proposed settings...
  14. doi request reprint Apoptosis in extracorporeal preserved inguinal fat flaps of the rat
    Christian Herold
    Department of Plastic, Hand and Reconstructive Surgery, Hanover Medical School, Germany
    Apoptosis 17:400-9. 2012
    ..Based on these findings, further research to modify the apoptotic pathways to ameliorate viability of fat tissue can be performed...
  15. pmc Schwann cell metabolic activity in various short-term holding conditions: implications for improved nerve graft viability
    Insa Janssen
    Department of Plastic, Hand and Reconstructive Surgery, Hannover Medical School, 30625 Hannover, Germany
    Int J Otolaryngol 2012:742183. 2012
    ..Greater SC viability at the time of surgical nerve grafting could contribute to improved axonal regeneration and remyelination after nerve transplantation, and thus more successful functional recovery...
  16. doi request reprint Resection of a large intra-abdominal tumor in the Mexican axolotl: a case report
    Bjoern Menger
    Department of Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Hannover, Germany
    Vet Surg 39:232-3. 2010
    ..This case report describes the surgical removal of an intra-abdominal tumor from a Mexican axolotl (Ambystoma mexicanum). The animal was admitted with left abdominal swelling that had increased over 4 months...
  17. ncbi request reprint Inhibition of apoptosis by expression of antiapoptotic proteins in recombinant human keratinocytes
    Claudia Y U Choi
    Department of Plastic, Hand and Reconstructive Surgery, Medical School Hannover, D 30625 Hannover, Germany
    Cell Transplant 16:663-74. 2007
    ..66), Faim (p = 0.42), or LFG (p = 0.44) expressing cells. Our results suggest that heterotopic expression of antiapoptotic proteins can induce the resistance of keratinocytes to a major mechanism of rejection...
  18. ncbi request reprint A Schwann cell-seeded intrinsic framework and its satisfactory biocompatibility for a bioartificial nerve graft
    Z L Shen
    Clinic of Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Germany
    Microsurgery 21:6-11. 2001
    ..We concluded that the arrangement of Schwann cell columns onto filaments was achieved, mimicking Bünger bands. It was shown that the biomaterials did not impede nerve regeneration...
  19. ncbi request reprint Identification of the non-specific cytotoxic cell receptor protein 1 (NCCRP1) in regenerating axolotl limbs
    Kerstin Reimers
    Department for Plastic, Hand and Reconstructive Surgery, Medical School Hannover, Podbielskistrasse 380, 30659 Hannover, Germany
    J Comp Physiol B 176:599-605. 2006
    ..Our findings suggest the existence of NCC in axolotl and a role of the innate immune system in the processes of limb regeneration...