G Hajak

Summary

Country: Germany

Publications

  1. ncbi request reprint Safety and tolerance of zolpidem in the treatment of disturbed sleep: a post-marketing surveillance of 16944 cases
    G Hajak
    Department of Psychiatry, Georg August University of Gottingen, Germany
    Int Clin Psychopharmacol 13:157-67. 1998
  2. ncbi request reprint A comparative assessment of the risks and benefits of zopiclone: a review of 15 years' clinical experience
    G Hajak
    Department of Psychiatry, Georg August University of Gottingen, Germany
    Drug Saf 21:457-69. 1999
  3. ncbi request reprint Salivary cortisol in panic attacks
    B Bandelow
    Department of Psychiatry, The University of Göttingen, Germany
    Am J Psychiatry 157:454-6. 2000
  4. ncbi request reprint The use of the Panic and Agoraphobia Scale in a clinical trial
    B Bandelow
    Department of Psychiatry, The University of Göttingen, Germany
    Psychiatry Res 77:43-9. 1998
  5. ncbi request reprint Nocturnal melatonin secretion and its modification by treatment in patients with sleep disorders
    A Rodenbeck
    Department of Psychiatry, University of Gottingen, Germany
    Adv Exp Med Biol 467:89-93. 1999
  6. ncbi request reprint Diurnal variation of cortisol in panic disorder
    B Bandelow
    Department of Psychiatry, University of Gottingen, Von Siebold Strasse 5, D 37075, Gottingen, Germany
    Psychiatry Res 95:245-50. 2000
  7. ncbi request reprint Relationship between cerebral blood flow velocities and cerebral electrical activity in sleep
    G Hajak
    Department of Psychiatry, , Germany
    Sleep 17:11-9. 1994
  8. ncbi request reprint Rebound insomnia after hypnotic withdrawal in insomniac outpatients
    G Hajak
    Department of Psychiatry, , Germany
    Eur Arch Psychiatry Clin Neurosci 248:148-56. 1998
  9. ncbi request reprint Application of a new statistical approach to evaluate a clinical trial with panic disorder patients
    B Bandelow
    Department of Psychiatry, University of Gottingen, Germany
    Eur Arch Psychiatry Clin Neurosci 249:21-7. 1999
  10. ncbi request reprint Neuroendocrine dysregulation in primary insomnia
    A Rodenbeck
    Department of Psychiatry and Psychotherapy, Georg August University of Gottingen, Von Siebold Str 5, 37075 Gottingen, Germany
    Rev Neurol (Paris) 157:S57-61. 2001

Detail Information

Publications24

  1. ncbi request reprint Safety and tolerance of zolpidem in the treatment of disturbed sleep: a post-marketing surveillance of 16944 cases
    G Hajak
    Department of Psychiatry, Georg August University of Gottingen, Germany
    Int Clin Psychopharmacol 13:157-67. 1998
    ..No life-threatening adverse event occurred. The adverse event profile reflected the pharmacological properties of zolpidem and underlined the cumulative good experience with the drug internationally...
  2. ncbi request reprint A comparative assessment of the risks and benefits of zopiclone: a review of 15 years' clinical experience
    G Hajak
    Department of Psychiatry, Georg August University of Gottingen, Germany
    Drug Saf 21:457-69. 1999
    ..5 billion units dispensed in more than 30 countries indicates that zopiclone is effective, well tolerated and an excellent alternative to benzodiazepines in the short term treatment of insomnia...
  3. ncbi request reprint Salivary cortisol in panic attacks
    B Bandelow
    Department of Psychiatry, The University of Göttingen, Germany
    Am J Psychiatry 157:454-6. 2000
    ..Increased cortisol levels have been associated with altered HPA function due to stress. The authors examined salivary cortisol levels in spontaneously occurring, unprovoked panic attacks...
  4. ncbi request reprint The use of the Panic and Agoraphobia Scale in a clinical trial
    B Bandelow
    Department of Psychiatry, The University of Göttingen, Germany
    Psychiatry Res 77:43-9. 1998
    ..The new Panic and Agoraphobia Scale (P & A) is a useful tool for measuring treatment efficacy in panic disorder trials...
  5. ncbi request reprint Nocturnal melatonin secretion and its modification by treatment in patients with sleep disorders
    A Rodenbeck
    Department of Psychiatry, University of Gottingen, Germany
    Adv Exp Med Biol 467:89-93. 1999
    ..We conclude that nocturnal melatonin secretion is primarily independent of sleep regulation but represents a neuroendocrine feature of chronically disturbed sleep...
  6. ncbi request reprint Diurnal variation of cortisol in panic disorder
    B Bandelow
    Department of Psychiatry, University of Gottingen, Von Siebold Strasse 5, D 37075, Gottingen, Germany
    Psychiatry Res 95:245-50. 2000
    ..Cortisol elevations seem to be more pronounced during the night and occurred mainly in more severely ill panic patients...
  7. ncbi request reprint Relationship between cerebral blood flow velocities and cerebral electrical activity in sleep
    G Hajak
    Department of Psychiatry, , Germany
    Sleep 17:11-9. 1994
    ..In light of the proposal that cortical energy consumption can be accounted for by cerebral electrical activity, the concept that cerebral perfusion during sleep is regulated solely by the metabolic rate must be reconsidered...
  8. ncbi request reprint Rebound insomnia after hypnotic withdrawal in insomniac outpatients
    G Hajak
    Department of Psychiatry, , Germany
    Eur Arch Psychiatry Clin Neurosci 248:148-56. 1998
    ..This result indicates that a deterioration of sleep after drug withdrawal is not apparent during a few days but may last for longer periods in some patients and is modified by marked night-to-night variations...
  9. ncbi request reprint Application of a new statistical approach to evaluate a clinical trial with panic disorder patients
    B Bandelow
    Department of Psychiatry, University of Gottingen, Germany
    Eur Arch Psychiatry Clin Neurosci 249:21-7. 1999
    ....
  10. ncbi request reprint Neuroendocrine dysregulation in primary insomnia
    A Rodenbeck
    Department of Psychiatry and Psychotherapy, Georg August University of Gottingen, Von Siebold Str 5, 37075 Gottingen, Germany
    Rev Neurol (Paris) 157:S57-61. 2001
    ..Taken together, the neuroendocrine dysregulation seems to be more expressed in chronic insomnia than in acute insomnia and may be a contributing factor in maintaining disturbed sleep...
  11. ncbi request reprint Rebound insomnia after abrupt clozapine withdrawal
    J Staedt
    Department of Psychiatry, Georg August University, Gottingen, Germany
    Eur Arch Psychiatry Clin Neurosci 246:79-82. 1996
    ....
  12. ncbi request reprint The sleep-improving effects of doxepin are paralleled by a normalized plasma cortisol secretion in primary insomnia. A placebo-controlled, double-blind, randomized, cross-over study followed by an open treatment over 3 weeks
    A Rodenbeck
    Department of Psychiatry and Psychotherapy, University of Gottingen, Von Siebold Strasse 5, 37075 Gottingen, Germany
    Psychopharmacology (Berl) 170:423-8. 2003
    ....
  13. ncbi request reprint Doxepin in the treatment of primary insomnia: a placebo-controlled, double-blind, polysomnographic study
    G Hajak
    Department of Psychiatry and Psychotherapy, , Germany
    J Clin Psychiatry 62:453-63. 2001
    ....
  14. ncbi request reprint Trimipramine in primary insomnia: results of a polysomnographic double-blind controlled study
    D Riemann
    Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
    Pharmacopsychiatry 35:165-74. 2002
    ..However, due to the large intra- and interindividual variance in the parameters of interest before and during treatment a larger sample size would have been necessary to strengthen the validity of our findings...
  15. ncbi request reprint Structural brain alterations following 5 days of intervention: dynamic aspects of neuroplasticity
    A May
    Department of Systems Neuroscience, University of Hamburg, Martinist 52, 20246 Hamburg, Germany
    Cereb Cortex 17:205-10. 2007
    ....
  16. ncbi request reprint Antidepressant effects of augmentative transcranial magnetic stimulation: randomised multicentre trial
    U Herwig
    Psychiatric University Hospital, University of Zurich, Lenggstrasse 31, Zurich, Switzerland
    Br J Psychiatry 191:441-8. 2007
    ..Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a new treatment option for depression. Previous studies were performed with low sample sizes in single centres and reported heterogeneous results...
  17. ncbi request reprint The challenge of chronic insomnia: is non-nightly hypnotic treatment a feasible alternative?
    G Hajak
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitatsstrasse 84, 93053 Regensburg, Germany
    Eur Psychiatry 18:201-8. 2003
    ..Published results show effective treatment of insomnia without any evidence of either adverse event associated with a discontinuous regimen or increased hypnotic use over the treatment period...
  18. ncbi request reprint Biochemical markers of cerebrovascular injury in sleep apnoea syndrome
    W Jordan
    Dept of Psychiatry and Psychotherapy, University Göttingen, Germany
    Eur Respir J 20:158-64. 2002
    ..There is a need for biochemical markers and more sensitive methods for detecting small cerebral injury in sleep apnoea syndrome...
  19. ncbi request reprint Smoking modulates neuroendocrine responses to ipsapirone in patients with panic disorder
    A Broocks
    Department of Psychiatry and Psychotherapy, University of Lubeck, 23538 Lubeck, Germany
    Neuropsychopharmacology 27:270-8. 2002
    ..The prevention of smoking during challenge sessions might not be the ideal approach in heavy smokers, since sudden abstinence from smoking is likely to affect neurobiological and possibly psychological responses to ipsapirone...
  20. ncbi request reprint [NISAS-2000: The "Nationwide Insomnia Screening and Awareness Study". Prevalence and interventions in primary care]
    H U Wittchen
    , Klin. Psychologie und Epidemiologie,
    Fortschr Med Orig 119:9-19. 2001
    ..The relatively low treatment rates and the high proportion of chronic patients receiving longterm prescription of benzodiazepines seem to be critical. Priorities for future agenda to improve this situation are discussed...
  21. ncbi request reprint Continuous versus non-nightly use of zolpidem in chronic insomnia: results of a large-scale, double-blind, randomized, outpatient study
    G Hajak
    Department of Psychiatry and Psychotherapy, University of Regensburg, Germany
    Int Clin Psychopharmacol 17:9-17. 2002
    ..Non-nightly zolpidem appears to be a feasible and safe additional option for the management of chronic insomnia...
  22. ncbi request reprint What treatments do patients with panic disorder and agoraphobia get?
    B Bandelow
    Department of Psychiatry, University of Gottingen, Germany
    Eur Arch Psychiatry Clin Neurosci 245:165-71. 1995
    ..9) were not rated highly effective by the patients. Among psychological treatments, patients were more satisfied with behavioural/cognitive therapy (2.6) than with psychodynamic therapies (1.5).(ABSTRACT TRUNCATED AT 250 WORDS)..
  23. ncbi request reprint Effects of chronic treatment with methadone and naltrexone on sleep in addicts
    J Staedt
    Department of Psychiatry, Georg August University, , Germany
    Eur Arch Psychiatry Clin Neurosci 246:305-9. 1996
    ..These data indicate that mu-agonists and mu-antagonists have different effects on sleep. The implications, especially the involvement of opioid-dopamine interactions on sleep and movements during sleep, are discussed...
  24. ncbi request reprint Positron emission tomography findings in obstructive sleep apnea patients with residual sleepiness treated with continuous positive airway pressure
    J Antczak
    Sleep Disorders and Research Centre, Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
    J Physiol Pharmacol 58:25-35. 2007
    ..Abnormal PET findings were concentrated in frontal area (found in 4 patients). The frontal abnormality seems to distinguish the OSAS patients with UPS from the whole OSAS population, examined in previous studies...