Research Topics
Genomes and GenesSpecies | A PetersSummaryAffiliation: GSF-National Research Center for Environment and Health Country: Germany Publications
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Detail Information
Publications
Associations between mortality and air pollution in central EuropeA Peters
GSF National Research Center for Environment and Health, Neuherberg, Germany
Environ Health Perspect 108:283-7. 2000....
[Particles in the outside air increase the risk of cardiovascular diseases]A Peters
GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg
Gesundheitswesen 67:S79-85. 2005..These pathomechanisms may contribute to the observed associations between ambient air pollution concentrations and cardiovascular disease exacerbation such as hospitalisation and mortality due to cardiovascular diseases...
Commentary: inflamed about ultrafine particles?Annette Peters
GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
Int J Epidemiol 35:1355-6. 2006
Exposure to traffic and the onset of myocardial infarctionAnnette Peters
Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
N Engl J Med 351:1721-30. 2004..This study was designed to assess whether exposure to traffic can trigger myocardial infarction...
Air pollution and inflammatory response in myocardial infarction survivors: gene-environment interactions in a high-risk groupAnnette Peters
GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
Inhal Toxicol 19:161-75. 2007....
Susceptible subgroups: the challenge of studying interactionsAnnette Peters
Institute of Epidemiology, GSF-National Research Center for Environment and Health, Ingolstaedter Landstr. 1, 85764 Nueherberg, Germany
Epidemiology 15:131-2. 2004
Cardiopulmonary mortality and air pollutionAnnette Peters
GSF National Research Centre for Environment and Health, Institute of Epidemiology, 85758, Neuherberg, Germany
Lancet 360:1184-5. 2002
Particulate matter and heart disease: evidence from epidemiological studiesAnnette Peters
GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstr 1, 85764 Neuherberg, Germany
Toxicol Appl Pharmacol 207:477-82. 2005..While this concept is consistent with the current understanding of the factors defining patients' vulnerability, the mechanisms and the time-scales on which the particle-induced vulnerability might operate are unknown...
Fibrinogen genes modify the fibrinogen response to ambient particulate matterAnnette Peters
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstaedter Landstrasse, Neuherberg 85764, Germany
Am J Respir Crit Care Med 179:484-91. 2009..Ambient particulate matter has been associated with systemic inflammation indicated by blood markers such as fibrinogen, implicated in promoting atherothrombosis...
Daily mortality and particulate matter in different size classes in Erfurt, GermanyMatthias Stölzel
GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
J Expo Sci Environ Epidemiol 17:458-67. 2007..003-1.060. No association between fine particle MC and mortality was found. This study shows that UFP, representing fresh combustion particles, may be an important component of urban air pollution associated with health effects...
Air temperature and the occurrence of myocardial infarction in Augsburg, GermanyKathrin Wolf
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, 85764 Neuherberg, Germany
Circulation 120:735-42. 2009..The objective of this study was to examine in detail the registry-based myocardial infarction (MI) rates and coronary deaths in relation to air temperature in the area of Augsburg, Germany...
Particulate air pollution is associated with an acute phase response in men; results from the MONICA-Augsburg StudyA Peters
Institute of Epidemiology, GSF-National Research Center for Environment and Health, Neuherberg, Postfach 1129, 08758 Oberschleissheim, Germany
Eur Heart J 22:1198-204. 2001....
Effects of air pollution on blood pressure: a population-based approachA Ibald-Mulli
GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, 85764 Neuherberg, Germany
Am J Public Health 91:571-7. 2001..This analysis assessed the association between blood pressure, meteorology, and air pollution in a random population sample...
Source apportionment of ambient fine particle size distribution using positive matrix factorization in Erfurt, GermanyWei Yue
Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
Sci Total Environ 398:133-44. 2008....
Impact of ambient air pollution on the differential white blood cell count in patients with chronic pulmonary diseaseIrene Brüske
Institute of Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environment and Health, Neuherberg, Germany
Inhal Toxicol 22:245-52. 2010..The increase of particulate and gaseous air pollution was associated with multiple changes in the differential white blood cell count in patients with chronic pulmonary diseases...
Air temperature and inflammatory responses in myocardial infarction survivorsAlexandra Schneider
Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
Epidemiology 19:391-400. 2008..The objective of this study was to analyze the association between air temperature and C-reactive protein, interleukin-6 and fibrinogen in postmyocardial infarction patients...
Daily measurement of organic compounds in ambient particulate matter in Augsburg, Germany: new aspects on aerosol sources and aerosol related health effectsJürgen Schnelle-Kreis
Helmholtz Zentrum Munchen, National Research Center for Environmental Health, Neuherberg, Germany
Biomarkers 14:39-44. 2009..The correlations found between formation of reactive oxygen species and the presence of specific organic compounds suggests an important influence of biomass combustion particles in PM2.5-associated oxidative stress...
High blood pressure, antihypertensive medication and lung function in a general adult populationEva Schnabel
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
Respir Res 12:50. 2011..Thus, aim of this analysis is to determine whether hypertension and antihypertensive medication have an adverse effect on lung function in a general adult population...
Seasonal and diurnal variation of PM2.5 apparent particle density in urban air in Augsburg, GermanyMike Pitz
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, 85764 Neuherberg, Germany
Environ Sci Technol 42:5087-93. 2008..rho2.5 has the potential to serve as a crude tracer for chemical composition and atmospheric processing and might play an important role when considering the associations between health effects and ambient particles...
Determinants of the acute-phase protein C-reactive protein in myocardial infarction survivors: the role of comorbidities and environmental factorsRegina Ruckerl
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Munich, Germany
Clin Chem 55:322-35. 2009..A joint analysis of the role of risk factors in predicting mean concentrations and variation of high-sensitivity CRP (hsCRP) in serum has not been carried out previously...
Increased asthma medication use in association with ambient fine and ultrafine particlesS von Klot
GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
Eur Respir J 20:691-702. 2002..The results suggest that reported asthma medication use and symptoms increase in association with particulate air pollution and gaseous pollutants such as nitrogen dioxide...
Epidemiological evidence on health effects of ultrafine particlesAngela Ibald-Mulli
GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, 85764 Neuherberg, Germany
J Aerosol Med 15:189-201. 2002..If these effects are confirmed by ongoing research, monitoring and regulation of particulate air pollution may need to be revised...
Quality control and quality assurance for particle size distribution measurements at an urban monitoring station in Augsburg, GermanyMike Pitz
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, 85764, Neuherberg, Germany
J Environ Monit 10:1017-24. 2008..The study demonstrates that the described QC and QA measures define both a high accuracy of the PSD measurements and their long-term comparability against data obtained in similar measurement programmes...
Air pollution and inflammation (interleukin-6, C-reactive protein, fibrinogen) in myocardial infarction survivorsRegina Ruckerl
GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
Environ Health Perspect 115:1072-80. 2007..Numerous studies have found that ambient air pollution has been associated with cardiovascular disease exacerbation...
Relationship between electrocardiographic and biochemical variables in coronary artery diseaseWei Yue
Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
Int J Cardiol 119:185-91. 2007..In this study, we aimed to explore the relationship between ECG and biochemical markers in a longitudinal study of coronary patients...
Effects of particulate air pollution on blood pressure and heart rate in subjects with cardiovascular disease: a multicenter approachAngela Ibald-Mulli
Institute of Epidemiology, GSF National Research Centre for Environment and Health, Ingolstadter Landstrasse 1, 85764 Neuherberg, Germany
Environ Health Perspect 112:369-77. 2004..However, particle effects might differ in cardiac patients because of medication intake and disease status, both affecting the autonomic control of the heart...
Air pollution and markers of inflammation and coagulation in patients with coronary heart diseaseRegina Ruckerl
GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany
Am J Respir Crit Care Med 173:432-41. 2006..Ambient air pollution has been shown to be associated with cardiovascular morbidity and mortality...
Air temperature and inflammatory and coagulation responses in men with coronary or pulmonary disease during the winter seasonRegina Hampel
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
Occup Environ Med 67:408-16. 2010..We investigated the associations between temperature and several blood markers in patients with coronary heart disease (CHD) and pulmonary disease (PD)...
Repolarization changes induced by air pollution in ischemic heart disease patientsAlexandra Henneberger
Ludwig Maximilians University of Munich, Munich, Germany
Environ Health Perspect 113:440-6. 2005..This study provides evidence suggesting an immediate effect of air pollution on repolarization duration, morphology, and variability representing myocardial substrate and vulnerability, key factors in the mechanisms of cardiac death...
Ambient source-specific particles are associated with prolonged repolarization and increased levels of inflammation in male coronary artery disease patientsWei Yue
Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
Mutat Res 621:50-60. 2007..These results suggest that traffic-related and combustion-generated particles show stronger adverse health impact with regard to cardiac effects, and that particles from different sources induce an acute phase response in these patients...
Ambient air pollution is associated with increased risk of hospital cardiac readmissions of myocardial infarction survivors in five European citiesStephanie von Klot
Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
Circulation 112:3073-9. 2005..The objective of this study was to evaluate the short-term effects of urban air pollution on cardiac hospital readmissions in survivors of myocardial infarction, a potentially susceptible subpopulation...
Intensity of physical exertion and triggering of myocardial infarction: a case-crossover studyStephanie von Klot
Institute of Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Germany
Eur Heart J 29:1881-8. 2008..We evaluated whether the risk of having an AMI triggered by physical exertion exhibits an exposure-response relationship, and whether it varies by ambient temperature or by taking place indoors or outdoors...
Runs of ventricular and supraventricular tachycardia triggered by air pollution in patients with coronary heart diseaseAnnette Berger
Institute of Epidemiology, GSF-National Research Center for Environment and Health, Ingolstaedter Landstrasse 1, D-85764 Neuherberg, Germany
J Occup Environ Med 48:1149-58. 2006..CONCLUSION: Elevated concentrations of fine and ultrafine particle increased the risk of arrhythmia in men with coronary heart disease...
Short-term mortality rates during a decade of improved air quality in Erfurt, GermanySusanne Breitner
Institute of Epidemiology, Helmholtz Zentrum Munchen German Research Center for Environmental Health, Neuherberg, Germany
Environ Health Perspect 117:448-54. 2009..Numerous studies have shown associations between ambient air pollution and daily mortality...
Cardiovascular effects of fine and ultrafine particlesHolger Schulz
Institute for Inhalation Biology, GSF-National Research Center for Environment and Health, Neuherberg/Munich, Germany
J Aerosol Med 18:1-22. 2005..Further studies are therefore needed to substantiate our current understanding of the pathophysiological links between PM exposure and adverse cardiovascular outcomes...
Changes in deceleration capacity of heart rate and heart rate variability induced by ambient air pollution in individuals with coronary artery diseaseAlexandra Schneider
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
Part Fibre Toxicol 7:29. 2010..The study assessed the association between deceleration capacity (DC) as well as heart rate variability (HRV) and ambient particulate matter (PM) in patients with coronary artery disease (CAD)...
Association of cardiac and vascular changes with ambient PM2.5 in diabetic individualsAlexandra Schneider
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
Part Fibre Toxicol 7:14. 2010..This study examined effects of short-term exposures to ambient PM2.5 on markers of systemic inflammation, coagulation, autonomic control of heart rate, and repolarization in 22 adults (mean age: 61 years) with type 2 diabetes...
Weather-induced ischemia and arrhythmia in patients undergoing cardiac rehabilitation: another difference between men and womenAlexandra Schneider
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
Int J Biometeorol 52:535-47. 2008..The observed effect on ST-segment depression could be a link between the association of weather changes and cardiovascular morbidity and mortality...
DNA variants, plasma levels and variability of C-reactive protein in myocardial infarction survivors: results from the AIRGENE studyMelanie Kolz
GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
Eur Heart J 29:1250-8. 2008..This study evaluated the association of gene polymorphisms with differences in C-reactive protein concentrations and assessed its intra-individual variability as a marker of individual response...
Age at menarche is associated with prediabetes and diabetes in women (aged 32-81 years) from the general population: the KORA F4 StudyD Stockl
Institute of Epidemiology II, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Ingolstadter Landstr 1, D 85764 Neuherberg, Germany
Diabetologia 55:681-8. 2012..The aim of this study was to examine the association between age at menarche and prediabetes as well as diabetes, considering confounding factors and the possible mediating role of adult obesity...
Medical care of type 2 diabetes in German disease management programmes: a population-based evaluationRenee G Stark
Helmholtz Zentrum Munchen, Institute for Health Economics and Healthcare Management, Neuherberg, Germany
Diabetes Metab Res Rev 27:383-91. 2011..The aim of this study was to compare healthcare quality and medical endpoints between diabetes management programme participants and patients receiving usual care designated as controls...
Endothelial dysfunction: associations with exposure to ambient fine particles in diabetic individualsAlexandra Schneider
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, Neuherberg, Germany
Environ Health Perspect 116:1666-74. 2008..5))] has been associated with cardiovascular and hematologic effects, especially in older people with cardiovascular disease. Some epidemiologic studies suggest that adults with diabetes also may be a particularly susceptible population...
Estimating the single nucleotide polymorphism genotype misclassification from routine double measurements in a large epidemiologic sampleIris M Heid
Helmholtz Zentrum Munchen German Research Center for Environmental Health, Institute of Epidemiology, 85764 Neuherberg, Germany
Am J Epidemiol 168:878-89. 2008..In situations with more substantial error, the presented approach using duplicate genotyping and the MC-SIMEX method is practical and helpful for quantifying the genotyping error and its impact...
The U.S. Environmental Protection Agency Particulate Matter Health Effects Research Centers Program: a midcourse report of status, progress, and plansMorton Lippmann
New York University School of Medicine, New York, New York, USA
Environ Health Perspect 111:1074-92. 2003..5 years) and longer-term goals. It consists of six sections: biological mechanisms, acute effects, chronic effects, dosimetry, exposure assessment, and the specific attributes of a coordinated PM centers program...
Environmental ozone effects in different population subgroupsPeter Hoppe
Institute and Outpatient Clinic for Occupational and Environmental Medicine, Ludwig Maximilians University, Ziemssenstr 1, D 80336 MUnchen, Germany
Int J Hyg Environ Health 206:505-16. 2003..18%) compared with elderly and athletes (both 5%). The results suggest that children and asthmatics have a higher risk of being ozone sensitive showing more ozone related acute lung function decrements than other population groups...
Particulate air pollution and risk of ST-segment depression during repeated submaximal exercise tests among subjects with coronary heart disease: the Exposure and Risk Assessment for Fine and Ultrafine Particles in Ambient Air (ULTRA) studyJuha Pekkanen
Unit of Environmental Epidemiology, National Public Health Institute, Kuopio, Finland
Circulation 106:933-8. 2002..We therefore assessed the associations between levels of the 3 main modes of urban aerosol distribution and the occurrence of ST-segment depressions during repeated exercise tests...
A case-crossover analysis of out-of-hospital coronary deaths and air pollution in Rome, ItalyFrancesco Forastiere
Department of Epidemiology, Rome E Local Health Authority, Via Santa Costanza 53, 00198 Rome, Italy
Am J Respir Crit Care Med 172:1549-55. 2005..Out-of-hospital coronary heart disease death is a major public health problem, but the association with air pollution is not well understood...
Aerosol particle number concentration measurements in five European cities using TSI-3022 condensation particle counter over a three-year period during health effects of air pollution on susceptible subpopulationsPasi Aalto
Department of Physical Sciences, University of Helsinki, Helsinki, Finland
J Air Waste Manag Assoc 55:1064-76. 2005..The study pointed out the influence of the selection of the measurement site and the configuration of the sampling line on the observed concentrations...
Weak correlation of ultrafine aerosol particle concentrations <800 nm between two sites within one cityThomas M Tuch
Institute for Tropospheric Research, Permoserstr 15, Leipzig, Germany
J Expo Sci Environ Epidemiol 16:486-90. 2006..A single background measurement site may not be sufficient for exposure assessment in these studies without taking spatial and temporal variability into account...
Effects of ultrafine and fine particulate and gaseous air pollution on cardiac autonomic control in subjects with coronary artery disease: the ULTRA studyKirsi L Timonen
Unit of Environmental Epidemiology, National Public Health Institute, Kuopio, Finland
J Expo Sci Environ Epidemiol 16:332-41. 2006..5 and HRV. The results suggest that the cardiovascular effects of ambient ultrafine and PM2.5 can differ from each other and that their effect may be modified by the characteristics of the exposed subjects and the sources of PM2.5...
Can we identify sources of fine particles responsible for exercise-induced ischemia on days with elevated air pollution? The ULTRA studyTimo Lanki
Environmental Epidemiology Unit, National Public Health Institute, Kuopio, Finland, and Environmental and Occupational Health Division, Institute for Risk Assessment Sciences, Utrecht University, The Netherlands
Environ Health Perspect 114:655-60. 2006..Our results suggest that the PM fraction originating from combustion processes, notably traffic, exacerbates ischemic heart diseases associated with PM mass...
Semi volatile organic compounds in ambient PM2.5. Seasonal trends and daily resolved source contributionsJürgen Schnelle-Kreis
Department of Chemistry, Bavarian Institute of Applied Environmental Research and Technology, BIfA GmbH, Am Mittleren Moos 46, 86167 Augsburg, Germany
Environ Sci Technol 41:3821-8. 2007..Like the SVOC, the factors showed strong seasonality with highest values in winter for factors 1-4 and in summer for factor 5...
Variability of serial lipoprotein-associated phospholipase A2 measurements in post myocardial infarction patients: results from the AIRGENE Study Center AugsburgNatalie Khuseyinova
Department of Internal Medicine II Cardiology, University of Ulm Medical Center, Ulm, Germany
Clin Chem 54:124-30. 2008..Implementation of Lp-PLA(2) measurement into clinical practice, however, requires data on the reliability of such measurements...
Spatial and temporal variation of particle number concentration in Augsburg, GermanyJosef Cyrys
Environmental Science Center of the University Augsburg, Universitätsstrasse 1a, 86159 Augsburg, Germany
Sci Total Environ 401:168-75. 2008....
Common genetic polymorphisms and haplotypes of fibrinogen alpha, beta, and gamma chains affect fibrinogen levels and the response to proinflammatory stimulation in myocardial infarction survivors: the AIRGENE studyBenedicte Jacquemin
Centre for Environmental Research, Municipal Institute of Medical Research, Barcelona, Spain
J Am Coll Cardiol 52:941-52. 2008..We also searched for genetic determinants affecting the responses of fibrinogen genes to proinflammatory stimulation...
When a myocardial infarction comes out of the not-so-blue airAnnette Peters
Circulation 114:2430-1. 2006
South-to-North gradient in lipid peroxidation in men with stable coronary artery disease in EuropeMaria Grau
Lipids and Cardiovascular Epidemiology Unit, Municipal Institute Medical Research IMIM Barcelona, Carrer Dr Aiguader, 88, E 08003 Barcelona, Spain
Eur Heart J 28:2841-9. 2007..The aim of our study was to determine whether differences exist in the degree of LDL oxidation in stable CAD patients from different regions of Europe...
