Christa Meisinger

..We investigated the gender-specific association of CKD with all-cause mortality, cardiovascular mortality, and incident myocardial infarction (MI) in a population-based cohort...

..The purpose of the study is to examine for the first time the association between 1-hour postload plasma glucose levels and known diabetes and 30-year total mortality...

..To examine gender-specific associations between gamma-glutamyltransferase (GGT) and incident type 2 diabetes mellitus in a representative population-based sample in Germany...

..To investigate the association between admission blood glucose levels and adverse outcomes after an incident acute myocardial infarction across a broad range of glucose levels in non-diabetic patients treated with modern therapy...

..To examine gender specific associations between sleep disturbance and incident type 2 diabetes mellitus in a representative population sample in Germany...

..We examined sex-specific associations between cigarette smoking and incident type 2 diabetes mellitus in Germany...

..We validated the diagnoses of self-reported acute myocardial infarction (AMI) treated in hospital...

..To investigate the relationship between body weight and the use of health care services among women from southern Germany...

..It remains controversial whether body mass index (BMI), waist circumference (WC), or waist-hip ratio (WHR) is a better risk predictor of type 2 diabetes...

..To examine sex-specific associations between sports activities in leisure time and incident myocardial infarction (MI) in a representative population sample in Germany...

..To examine gender-specific associations between sleep duration and sleep complaints and incident myocardial infarction (MI)...

..Use of beta-blockers is associated with a reduced risk of fractures in middle-aged and older subjects from the general population...

..In conclusion, data from the MONICA/KORA Augsburg studies suggest that it should become an important public health priority to prevent diabetes mellitus...

..These factors open new insights for our understanding of the multifaceted etiology of suicide risks offering new strategies for early detection of subjects at risk...

..Therefore, the aim of this study was to compare associations of markers of inflammation with type 2 diabetes risk between men and women...

..This association is independent of a generalized proinflammatory state, but subjects with elevated levels of several inflammatory markers seem to be particularly prone to develop type 2 diabetes...

..To examine sex-specific associations between cardiovascular risk factors, a parental history of diabetes, and type 2 diabetes mellitus (DM)...

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..However, long-term mortality was higher in patients with AMI and DM, particularly in women...

..We examined time patterns and long term time trends of pre-hospital delay time (PHDT) of STEMI patients...

..USF1 is a transcription factor for APOA5...

..Several studies have investigated associations between the -174G>C single nucleotide polymorphism (rs1800795) of the IL6 gene and phenotypes related to type 2 diabetes mellitus (T2DM) but presented inconsistent results...

..Health effects of traffic-related air pollution may need to be updated, taking into account individual time spent in traffic and outdoors, to adequately protect the public...

..To provide valid clinical data of early in-hospital deaths with presumed acute myocardial infarction (AMI) who are often not included in clinical trials or registries...

..32 (0.89 to 1.96); women, 1.03 (0.64 to 1.67)]. In this study, vWF was not associated with risk of type 2 diabetes. CONCLUSIONS: These data support a role of endothelial dysfunction in the etiology of type 2 diabetes...

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..Some of the identified patterns of multimorbidity and their overlap may indicate common underlying pathological mechanisms...

..To examine sex-specific associations between living alone and incident Type 2 diabetes mellitus in a representative population sample in Germany...

..Therefore, we aimed to identify sex-specific characteristics associated with heavy daily cigarette smoking...

..The aim of this study was to examine the association between age at menarche and the metabolic syndrome (IDF and NCEP ATP III classification) and its components...

..Living alone is considered a psychosocial risk factor. We studied the relationship between living alone, cardiovascular risk factors and mortality...

..Inflammation could be one mechanism by which known risk factors for diabetes mellitus, such as obesity, smoking, and hypertension, promote the development of diabetes mellitus...

..Furthermore, the data suggest a different mechanism of APOA5 impact on MetS in Caucasians, as variant c.56C>G (not analyzed in the Japanese study) and not -1131T>C, as in the Japanese subjects, was associated with MetS...

..Little is known about sex-specific influences of obesity, hypertension, and other risk factors on left ventricular mass in pre-diabetic or diabetic subjects...

..We sought to investigate whether increased blood glucose levels on admission in nondiabetic patients with first AMI are predictive for future T2DM...

..To examine sex-specific associations between blood pressure levels and incident type 2 diabetes mellitus in a representative population sample in Germany...

..Stratification by AMI type and troponin showed that CRP was a better short-term risk predictor for patients with non-STEMI, and troponin was, for patients with STEMI...

..A joint analysis of the role of risk factors in predicting mean concentrations and variation of high-sensitivity CRP (hsCRP) in serum has not been carried out previously...

..However, long-term data are limited regarding 'hard' endpoints and quality of life in unselected elderly patients in 'real world' settings...

..Physical activity has recently been established as a potential modifier of the inflammatory process, suggesting that it mitigates inflammation and consequently reduces the incidence of several chronic diseases such as cardiovascular events...

..We evaluated whether the risk of having an AMI triggered by physical exertion exhibits an exposure-response relationship, and whether it varies by ambient temperature or by taking place indoors or outdoors...

..The population-based approach demonstrates a substantial proportion of subjects suffering from SID, particularly in older age groups...

..This study investigated differences regarding degree, duration, and motivation of abstinence within a group of individuals with very low alcohol consumption. Reliability of self-reported alcohol abstinence was examined...

..The anti-atherogenic apolipoprotein A-IV will be one of our candidates of interest...

..Its flexible design enables both the use of prior knowledge and the generation of new knowledge on connection of multiple phenotypes. A software program for PSEA based on GWAS results is available upon request...

..We examined if there are associations between reproductive parameters and uric acid levels in a female population-based sample...

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..The proportion of the variance of serum uric acid concentrations explained by genotypes was about 1.2% in men and 6% in women, and the percentage accounted for by expression levels was 3.5% in men and 15% in women...

..To evaluate healthcare and outcomes of disease management programmes (DMPs) for patients with coronary heart disease (CHD) in primary care, and to assess selection of enrollment for these programmes...

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..To investigate the effect of weight change and weight fluctuations on all-cause-mortality in men...

..This paper describes the study design, frequency data on cardiovascular and psychosocial factors at baseline survey, and findings of three 5 year follow-up medical examinations. Life status was followed for 30 years...

..CONCLUSION: ApoB and the apoB/apoA-I ratio were strong predictors of coronary events in middle-aged men and women, whereas apoA-I did not add significantly to the estimation of future coronary risk...

..The presented results show positive developments, but underscore the necessity for increased primary prevention...

..To characterise the influence of the fat free mass on the metabolite profile in serum samples from participants of the population-based KORA (Cooperative Health Research in the Region of Augsburg) S4 study...

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..Thus, aim of this analysis is to determine whether hypertension and antihypertensive medication have an adverse effect on lung function in a general adult population...

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..97; 95% CI: 0.44-2.11). CONCLUSIONS/INTERPRETATION: Leisure time physical activity is effective in preventing type 2 diabetes, especially in nonobese women, in the general population...

..To assess the association between serum 25-hydroxyvitamin D (25-OHD) and incident type 2 diabetes and to determine whether the association is mediated by subclinical inflammation...

..The aim of this study was to assess the impact of myocardial infarction (MI) on health-related quality of life (HRQL) in MI survivors measured by EuroQol (EQ-5D) and to compare it with the general population...

..The objective of this study was to examine in detail the registry-based myocardial infarction (MI) rates and coronary deaths in relation to air temperature in the area of Augsburg, Germany...

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..These findings may not only enhance our understanding of platelet activation and function, but may also provide a focus for several novel research avenues...

..In conclusion, women and men did not differ regarding the chief AMI symptoms of chest pain or feelings of tightness or pressure and diaphoresis. However, women were more likely to have additional symptoms...

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..To determine regional variations in the prevalence and applied therapy regimes of current menopausal hormone therapy (HT) in Germany...

..Despite such substantial epidemiologic differences, the community management of hypertension was of almost identical quality...

..CONCLUSIONS: Elevated concentrations of oxLDL are predictive of future CHD events in apparently healthy men. Thus, oxLDL may represent a promising risk marker for clinical CHD complications and should be evaluated in further studies...

..We investigated the interrelation of recruitment efforts and expense with potential nonresponse bias based on data from a large health survey...

..The association with height seems to be the central factor indicating an influence of IL-6 on growth through impaired bone metabolism. However, the complex relationships need further investigation...

..Therefore, the theme number 1 for the population must be intensified activities of primary prevention...

..To investigate whether serum gamma-glutamyltransferase (GGT) is an independent predictor for incident coronary events in initially healthy men from the general population...

..Furthermore, results obtained in the full cohort for selected exposures are compared with results obtained in the case-cohort study...

..For the MONICA Augsburg population, MI-morbidity, mortality, and 28-day case fatality and their determinants were assessed by gender, and suggestions for an intensified acute care program were presented...

..The mortality rate from cardiovascular disease is higher in northern than southern Germany. To illuminate this further current epidemiological data on arterial hypertension were obtained and compared with previously collected data...

..The aim of our study was to examine the associations between USF1 polymorphisms and lipid parameters as well as incident type 2 diabetes mellitus (T2DM) in German Caucasians...

..Since CHD and type 2 diabetes share many risk factors, the aim of this study was to assess whether elevated sTM levels are associated with a lower incidence of type 2 diabetes...

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..To examine the extent to which evidence-based beneficial therapy is applied in practice, whether this is changing over time and is associated with improved outcomes...

..Specific IgE antibodies are often detected without any clinical manifestation of allergies. We aimed to analyse the predictivity of allergic sensitization for incident symptoms of allergic diseases in adults during a 10-year follow-up...

..Chronic kidney disease (CKD) is common, but the longitudinal effects of CKD and associated comorbidities on health care costs in the general population are unknown...

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..These findings support replication evidence that TCF7L2 variants increase type 2 diabetes risk. TCF7L2 may primarily affect pancreatic beta cell function...

..0001). CONCLUSION: Both ABI and number of plaque-affected arteries are strong predictors for incident MI and cardiovascular and total mortality...

..The programme is expected to influence patient readmission, mortality and quality of life, and thus to reduce health care costs compared with usual care. In this paper the study protocol is described...

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..Ambient particulate matter has been associated with systemic inflammation indicated by blood markers such as fibrinogen, implicated in promoting atherothrombosis...

..The objective of this study was to analyze the association between air temperature and C-reactive protein, interleukin-6 and fibrinogen in postmyocardial infarction patients...

..To evaluate whether reduced heart rate variability (HRV), prolonged corrected QT (QTc) interval, or increased QT dispersion (QTD) are predictors of mortality in the general diabetic and nondiabetic population...

..The aim of this study was to determine the prevalence and risk factors of polyneuropathy in subjects with diabetes, impaired fasting glucose (IFG), impaired glucose tolerance (IGT), or normal glucose tolerance (NGT)...

..We sought to assess the potential of CRP measurements to enhance risk prediction based on the Framingham Risk Score (FRS) in a large cohort of middle-aged men from the general population...

..Because other chronic diseases are also associated with an inflammatory response, we sought to assess the association of high-sensitivity CRP (hsCRP) with total and cause-specific mortality in a large cohort of middle-aged men...

..The 10-year risk of fatal CVD predicted by SCORE Germany (P) was evaluated against the risk observed in the general population using official mortality data (O)...

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