J Heinrich

Summary

Affiliation: GSF-National Research Center for Environment and Health
Country: Germany

Publications

  1. pmc Pre-natal and post-natal exposure to respiratory infection and atopic diseases development: a historical cohort study
    Anne Zutavern
    GSF Institut für Epidemiologie, Neuherberg, Germany
    Respir Res 7:81. 2006
  2. pmc Long-term air pollution exposure and living close to busy roads are associated with COPD in women
    Tamara Schikowski
    Institut fur Umweltmedizinische Forschung, Heinrich Heine University of Dusseldorf, Auf m Hennekamp50, 40225 Dusseldorf, Germany
    Respir Res 6:152. 2005
  3. pmc Does respiratory health contribute to the effects of long-term air pollution exposure on cardiovascular mortality?
    Tamara Schikowski
    Institut fur Umweltmedizinische Forschung, Heinrich Heine University Dusseldorf, Auf m Hennekamp50, 40225 Dusseldorf, Germany
    Respir Res 8:20. 2007
  4. ncbi request reprint Nicotine and cotinine in adults' urine: The German Environmental Survey 1998
    Joachim Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, D 85764 Neuherberg, Germany
    J Expo Anal Environ Epidemiol 15:74-80. 2005
  5. ncbi request reprint Traffic at residential address, respiratory health, and atopy in adults: the National German Health Survey 1998
    Joachim Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, D 85764 Neuherberg, Germany
    Environ Res 98:240-9. 2005
  6. ncbi request reprint Reproducibility of allergen, endotoxin and fungi measurements in the indoor environment
    Joachim Heinrich
    GSF Institute of Epidemiology, POB 1129, D 85758 Neuherberg, Germany
    J Expo Anal Environ Epidemiol 13:152-60. 2003
  7. ncbi request reprint Allergens and endotoxin on mothers' mattresses and total immunoglobulin E in cord blood of neonates
    J Heinrich
    GSF Institute of Epidemiology, National Research Centre for Environment and Health, Neuherberg, Germany
    Eur Respir J 20:617-23. 2002
  8. pmc Exposure to traffic related air pollutants: self reported traffic intensity versus GIS modelled exposure
    J Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, D 85764 Neuherberg, Germany
    Occup Environ Med 62:517-23. 2005
  9. ncbi request reprint Erfurt Male cohort Study (ERFORT Study). Study design and descriptive results
    Joachim Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Cent Eur J Public Health 15:51-7. 2007
  10. ncbi request reprint Fine particles, a major threat to children
    Joachim Heinrich
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Int J Hyg Environ Health 210:617-22. 2007

Collaborators

Detail Information

Publications163 found, 100 shown here

  1. pmc Pre-natal and post-natal exposure to respiratory infection and atopic diseases development: a historical cohort study
    Anne Zutavern
    GSF Institut für Epidemiologie, Neuherberg, Germany
    Respir Res 7:81. 2006
    ..Exposure to infection indicating sub-clinical infection rather than clinical infection might protect from atopic diseases...
  2. pmc Long-term air pollution exposure and living close to busy roads are associated with COPD in women
    Tamara Schikowski
    Institut fur Umweltmedizinische Forschung, Heinrich Heine University of Dusseldorf, Auf m Hennekamp50, 40225 Dusseldorf, Germany
    Respir Res 6:152. 2005
    ..We especially focused on COPD as defined by GOLD criteria and additionally compared the effects of air pollution on respiratory symptoms by questionnaire data and by lung function measurements...
  3. pmc Does respiratory health contribute to the effects of long-term air pollution exposure on cardiovascular mortality?
    Tamara Schikowski
    Institut fur Umweltmedizinische Forschung, Heinrich Heine University Dusseldorf, Auf m Hennekamp50, 40225 Dusseldorf, Germany
    Respir Res 8:20. 2007
    ..The aim of this study was to investigate whether respiratory health at baseline contributes to the effects of long-term exposure to high levels of air pollution on cardiovascular mortality in a cohort of elderly women...
  4. ncbi request reprint Nicotine and cotinine in adults' urine: The German Environmental Survey 1998
    Joachim Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, D 85764 Neuherberg, Germany
    J Expo Anal Environ Epidemiol 15:74-80. 2005
    ..A new federal bill to diminish environmental tobacco smoke (ETS) exposure in the workplace was recently passed in Germany, but protection of nonsmokers from smoking family members at home needs more attention...
  5. ncbi request reprint Traffic at residential address, respiratory health, and atopy in adults: the National German Health Survey 1998
    Joachim Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, D 85764 Neuherberg, Germany
    Environ Res 98:240-9. 2005
    ..91-1.20)). We conclude that exposure to traffic-related air pollutants increases the risk of nonallergic respiratory symptoms and to a lesser degree the risk of hay fever and allergic sensitization but not the risk of asthma in adults...
  6. ncbi request reprint Reproducibility of allergen, endotoxin and fungi measurements in the indoor environment
    Joachim Heinrich
    GSF Institute of Epidemiology, POB 1129, D 85758 Neuherberg, Germany
    J Expo Anal Environ Epidemiol 13:152-60. 2003
    ..However, repeated measurements of fungi levels were only weakly correlated and thus repeated observations for assessment of annual means of total spore counts are needed...
  7. ncbi request reprint Allergens and endotoxin on mothers' mattresses and total immunoglobulin E in cord blood of neonates
    J Heinrich
    GSF Institute of Epidemiology, National Research Centre for Environment and Health, Neuherberg, Germany
    Eur Respir J 20:617-23. 2002
    ..35 kU x L(-1) was used as cut-off. These results, showing an association between prenatal allergen and endotoxin exposures and immunoglobulin E production, suggest that the development of foetal immune responses may be affected...
  8. pmc Exposure to traffic related air pollutants: self reported traffic intensity versus GIS modelled exposure
    J Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, D 85764 Neuherberg, Germany
    Occup Environ Med 62:517-23. 2005
    ..In epidemiological studies of the potential health effects of traffic related air pollution, self reported traffic intensity is a commonly used, but rarely validated, exposure variable...
  9. ncbi request reprint Erfurt Male cohort Study (ERFORT Study). Study design and descriptive results
    Joachim Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Cent Eur J Public Health 15:51-7. 2007
    ..This paper describes the study design, frequency data on cardiovascular and psychosocial factors at baseline survey, and findings of three 5 year follow-up medical examinations. Life status was followed for 30 years...
  10. ncbi request reprint Fine particles, a major threat to children
    Joachim Heinrich
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Int J Hyg Environ Health 210:617-22. 2007
    ..Here, we restrict the review on the impact of fine particle exposure on children's health to the following outcomes: infant death, lung function, respiratory symptoms and reproductive outcomes...
  11. ncbi request reprint Pets and vermin are associated with high endotoxin levels in house dust
    J Heinrich
    GSF, Institute of Epidemiology, Munich, Germany
    Clin Exp Allergy 31:1839-45. 2001
    ..A higher microbial exposure in general and in particular to endotoxin in early childhood might contribute to this lower risk of atopy...
  12. ncbi request reprint Trends in prevalence of atopic diseases and allergic sensitization in children in Eastern Germany
    J Heinrich
    GSF National Research Centre for Environment and Health Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 19:1040-6. 2002
    ....
  13. ncbi request reprint [European Community Respiratory Health Survey in Adults (ECRHS)]
    J Heinrich
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Deutschland
    Pneumologie 56:297-303. 2002
    ....
  14. ncbi request reprint [Environmental surveys in the areas of Bitterfeld, Hettstedt and a comparative area in 1992-2000]
    J Heinrich
    GSF Forschungszentrum für Umwelt und Gesundheit GmbH, Institut fur Epidemiologie, Neuherberg
    Gesundheitswesen 64:675-82. 2002
    ....
  15. ncbi request reprint Decline of ambient air pollution and respiratory symptoms in children
    J Heinrich
    Forschungszentrum für Umwelt und Gesundheit, Institut fuer Epidemiologie, and Lehrstuhl für Epidemiologie, Ludwig Maximilians Universitaet München, Neuherberg, Germany
    Am J Respir Crit Care Med 161:1930-6. 2000
    ..76; CI: 0.66 to 0.88) after adjustment for several potential predictors. In conclusion, we found that the prevalence of nonasthmatic respiratory symptoms decreased from the first period to the second period in all three study areas...
  16. ncbi request reprint Improved air quality in reunified Germany and decreases in respiratory symptoms
    Joachim Heinrich
    GSF, National Research Center for Environment and Health Institute for Epidemiology, PO Box 1129, D 85758 Oberschleissheim, Germany
    Epidemiology 13:394-401. 2002
    ..Previous research on air pollution effects has found associations with chronic adverse health effects even at the relatively low levels of ambient particulates currently measured in most urban areas...
  17. ncbi request reprint Is the prevalence of atopic diseases in East and West Germany already converging?
    J Heinrich
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Oberschleissheim, Germany
    Eur J Epidemiol 14:239-45. 1998
    ..It is not yet clear if this is due to a true increase in morbidity or only to a higher awareness for these diseases among doctors and the public...
  18. ncbi request reprint [Housing conditions and allergic sensitization in children]
    J Heinrich
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg
    Zentralbl Hyg Umweltmed 201:211-28. 1998
    ..Modern living conditions are associated with a higher odds of allergic sensitization...
  19. ncbi request reprint Trends in allergies among children in a region of former East Germany between 1992-1993 and 1995-1996
    J Heinrich
    GSF Forshungszentrum fuer Umwelt und Gesundheit, Institut fuer Epidemiologie, Postfach 1129, D 85758 Neuherberg, Germany
    Eur J Med Res 4:107-13. 1999
    ..In conclusion, there were no significant changes in the prevalence of asthma, allergic rhinitis, or self-reported symptoms of allergic diseases...
  20. ncbi request reprint Rhinitis and blood pressure in adults
    Joachim Heinrich
    GSF Institute of Epidemiology, PO Box 1129, D 85758 Neuherberg, Germany
    Am J Respir Crit Care Med 168:1243-5. 2003
    ..We could not confirm the conclusion of the previous study that men with rhinitis need special attention for blood pressure control...
  21. ncbi request reprint Cat allergen level: its determinants and relationship to specific IgE to cat across European centers
    Joachim Heinrich
    GSF, National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    J Allergy Clin Immunol 118:674-81. 2006
    ..Cat allergen level in settled house dust and its determinants in Europe are unknown...
  22. ncbi request reprint Air pollution and otitis media: a review of evidence from epidemiologic studies
    Joachim Heinrich
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Curr Allergy Asthma Rep 4:302-9. 2004
    ....
  23. ncbi request reprint Traffic related pollutants in Europe and their effect on allergic disease
    Joachim Heinrich
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Curr Opin Allergy Clin Immunol 4:341-8. 2004
    ..However, the results from epidemiologic research provide a more complex picture...
  24. ncbi request reprint Nonallergic respiratory morbidity improved along with a decline of traditional air pollution levels: a review
    J Heinrich
    GSF Institute of Epidemiology, P O Box 1129, D 85758 Oberschleissheim, Germany
    Eur Respir J Suppl 40:64s-69s. 2003
    ....
  25. ncbi request reprint Blood pressure and rhinitis in adults: results of the MONICA/KORA-study
    Joachim Heinrich
    National Research Center for Environment and Health, GSF Institute of Epidemiology, PO Box 1129, D 85758 Neuherberg, Germany
    J Hypertens 22:889-92. 2004
    ..A study of 330 adults reported increased systolic blood pressure and higher hypertension prevalence rates in men with rhinitis. The authors replicated this study...
  26. ncbi request reprint Respiratory symptoms in relation to indoor exposure to mite and cat allergens and endotoxins. Indoor Factors and Genetics in Asthma (INGA) Study Group
    U Gehring
    GSF-National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 18:555-63. 2001
    ..The risk is increased if subjects are exposed to a mixture of allergens or if they are sensitized in addition to high exposure...
  27. pmc Early life risk factors of being overweight at 10 years of age: results of the German birth cohorts GINIplus and LISAplus
    Z Pei
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Neuherberg, Germany
    Eur J Clin Nutr 67:855-62. 2013
    ..To develop a prediction model that quantifies the risk of being overweight at 10 years of age...
  28. ncbi request reprint Exposure to endotoxin decreases the risk of atopic eczema in infancy: a cohort study
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    J Allergy Clin Immunol 108:847-54. 2001
    ....
  29. pmc Beta(1-->3)-glucan in house dust of German homes: housing characteristics, occupant behavior, and relations with endotoxins, allergens, and molds
    U Gehring
    GSF - National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Environ Health Perspect 109:139-44. 2001
    ..4). We conclude that that the amount of dust sampled can be used as a proxy for hygiene and that beta(1-->3)-glucan concentrations per square meter are related to the amount of dust sampled...
  30. ncbi request reprint Perinatal exposure to endotoxin and the development of eczema during the first 6 years of life
    C M Chen
    Helmholtz Centre Munich, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Dermatol 35:238-44. 2010
    ..Previous studies have reported a protective association between high levels of exposure to endotoxin during infancy and the development of subsequent eczema within the first 6 months of life...
  31. doi request reprint FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children
    M Standl
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Munich, Germany
    Clin Exp Allergy 41:1757-66. 2011
    ..The association between dietary fatty acid intake and the development of atopic diseases has been inconsistent. This could be due to inter-individual genetic differences in fatty acid metabolism...
  32. doi request reprint FADS gene cluster modulates the effect of breastfeeding on asthma. Results from the GINIplus and LISAplus studies
    M Standl
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology I, Ingolstadter Landstrasse 1, Neuherberg, Germany
    Allergy 67:83-90. 2012
    ..Therefore, we evaluated the influence of the FADS1 FADS2 gene cluster polymorphisms on the association between BF and asthma...
  33. doi request reprint Growth of infants fed formula rich in canola oil (low erucic acid rapeseed oil)
    Peter Rzehak
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Nutr 30:339-45. 2011
    ..The aim of this study is to investigate whether infant formulas containing canola oil support normal growth in infants as assessed by weight and length gain...
  34. doi request reprint Regional and socio-economic differences in food, nutrient and supplement intake in school-age children in Germany: results from the GINIplus and the LISAplus studies
    Stefanie Sausenthaler
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstadter Landstr 1, 85764 Neuherberg, Germany
    Public Health Nutr 14:1724-35. 2011
    ..To describe regional differences between eastern and western Germany with regard to food, nutrient and supplement intake in 9-12-year-old children, and analyse its association with parental education and equivalent income...
  35. doi request reprint Common variants in FCER1A influence total serum IgE levels from cord blood up to six years of life
    C M Chen
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 64:1327-32. 2009
    ..In a recent genome wide scan, a functional promoter variant (rs2251746) in the gene encoding the alpha chain of the high affinity receptor for immunoglobulin E (IgE) (FCER1A) was identified as major determinant of serum IgE levels...
  36. pmc Respiratory health and individual estimated exposure to traffic-related air pollutants in a cohort of young children
    V Morgenstern
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Occup Environ Med 64:8-16. 2007
    ....
  37. ncbi request reprint Repeated measurements of allergens and endotoxin in settled house dust over a time period of 6 years
    R Topp
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Allergy 33:1659-66. 2003
    ..This singly measured biocontaminant concentration is related to adverse respiratory outcomes such as asthma, wheeze or others...
  38. ncbi request reprint Glutathione-S-transferase P1, early exposure to mould in relation to respiratory and allergic health outcomes in children from six birth cohorts. A meta-analysis
    C G Tischer
    Helmholtz Centre Munich, German Research Centre for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany
    Allergy 68:339-46. 2013
    ..It has been suggested that functional polymorphisms of the GSTP1 gene may influence the risk for allergic disorders through an impaired defence against oxidant injury...
  39. ncbi request reprint Farming, rural lifestyle and atopy in adults from southern Germany--results from the MONICA/KORA study Augsburg
    B Filipiak
    GSF National Reseach Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Allergy 31:1829-38. 2001
    ..We compared the prevalence of allergic diseases in farmers, and rural, suburban and urban residents in the small geographical area of Augsburg in southern Germany...
  40. ncbi request reprint Exposure to house dust endotoxin and allergic sensitization in adults
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 59:946-52. 2004
    ..It has been suggested that exposure to elevated levels of endotoxin decreases the risk of allergic sensitization...
  41. ncbi request reprint Health impacts of second-hand exposure to cat allergen Fel d 1 in infants
    A Heissenhuber
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 58:154-7. 2003
    ..Therefore we restricted our analysis to infants without a cat at home since birth...
  42. ncbi request reprint Traffic-related air pollution and respiratory health during the first 2 yrs of life
    U Gehring
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 19:690-8. 2002
    ..There was some indication of an association between traffic-related air pollution and symptoms of cough. Due to the very young age of the infants, it was too early to draw definitive conclusions from this for the development of asthma...
  43. doi request reprint Associations between BMI and the FTO gene are age dependent: results from the GINI and LISA birth cohort studies up to age 6 years
    Peter Rzehak
    Institute of Epidemiology, German Research Center for Environmental Health, Helmholtz Zentrum Munchen, Neuherberg, Germany
    Obes Facts 3:173-80. 2010
    ..However, little is known about the longitudinal dynamics of these polymorphisms on body mass index (BMI), overweight, and obesity...
  44. ncbi request reprint Increasing prevalence of bronchial hyperresponsiveness in three selected areas in East Germany. Bitterfeld Study Group
    C Frye
    , Institut fur Epidemiologie, Neuherberg, Germany
    Eur Respir J 18:451-8. 2001
    ..The present results give indirect evidence, that less respiratory infections may be associated with higher bronchial hyperresponsiveness...
  45. ncbi request reprint Exposure to pets and allergies in children
    Bernd Hölscher
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Pediatr Allergy Immunol 13:334-41. 2002
    ..In conclusion, this study supports the hypothesis of a potential protective mechanism related to dog exposure in early life, especially for children of atopic parents. However, this association was found only for dogs and not for cats...
  46. ncbi request reprint Predictivity of allergic sensitization (RAST) for the onset of allergic diseases in adults
    Y Schoefer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 63:81-6. 2008
    ..Specific IgE antibodies are often detected without any clinical manifestation of allergies. We aimed to analyse the predictivity of allergic sensitization for incident symptoms of allergic diseases in adults during a 10-year follow-up...
  47. ncbi request reprint Levels and predictors of endotoxin in mattress dust samples from East and West German homes
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Indoor Air 14:284-92. 2004
    ..None of these factors explains the difference in infant's mattress dust endotoxin between Leipzig and Munich or could be used as a surrogate for endotoxin...
  48. doi request reprint Prenatal and postnatal tobacco smoke exposure and development of insulin resistance in 10 year old children
    Elisabeth Thiering
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Int J Hyg Environ Health 214:361-8. 2011
    ..Positive dose-dependent associations and independent effects of postnatal exposure suggest involvement of environmental tobacco smoke in the risk for development of insulin resistance in children...
  49. ncbi request reprint Early allergic sensitizations and their relevance to atopic diseases in children aged 6 years: results of the GINI study
    I Brockow
    Department of Pediatrics, Technical University of Munich, Munich, Germany
    J Investig Allergol Clin Immunol 19:180-7. 2009
    ..Only a few studies have analyzed the value of early sensitization in predicting the development of atopic disease. The relevance of low immunoglobulin (Ig) E antibody levels in this respect also remains unclear...
  50. ncbi request reprint Atopic disease and its determinants -- a focus on the potential role of childhood infection
    A Resch
    Department of Medical Informatics, Biometry, and Epidemiology, Ludwig Maximilians University, Munich, Germany
    Clin Exp Allergy 34:1184-91. 2004
    ..Atopic diseases develop on a genetic background and are modulated by environmental factors among which some infectious diseases are thought to have a protective influence...
  51. ncbi request reprint Stress-related maternal factors during pregnancy in relation to childhood eczema: results from the LISA Study
    S Sausenthaler
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    J Investig Allergol Clin Immunol 19:481-7. 2009
    ..Stress has been suggested to impact the onset and exacerbation of eczema and other atopic disorders. Whether early exposure to stress-related factors might exert long-term effects remains to be clarified...
  52. doi request reprint Respiratory health in children, and indoor exposure to (1,3)-β-D-glucan, EPS mould components and endotoxin
    C Tischer
    Institute of EpidemiologyHelmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany
    Eur Respir J 37:1050-9. 2011
    ..The reasons for the differences between countries are not clear...
  53. ncbi request reprint Lung cancer risk in male workers occupationally exposed to diesel motor emissions in Germany
    I Bruske-Hohlfeld
    GSF Institute of Epidemiology, National Research Center for Environment and Health, Neuherberg
    Am J Ind Med 36:405-14. 1999
    ..Although in several epidemiological studies exposure to diesel motor emissions (DME) shows an elevated lung cancer risk, it is still controversial whether DME is a human carcinogen...
  54. ncbi request reprint Daily mortality and particulate matter in different size classes in Erfurt, Germany
    Matthias Stölzel
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    J Expo Sci Environ Epidemiol 17:458-67. 2007
    ..003-1.060. No association between fine particle MC and mortality was found. This study shows that UFP, representing fresh combustion particles, may be an important component of urban air pollution associated with health effects...
  55. ncbi request reprint Domestic cat allergen and allergic sensitisation in young children
    Chih Mei Chen
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, D 85764 Neuherberg, Germany
    Int J Hyg Environ Health 211:337-44. 2008
    ..The mixed results may be explained by differences in age and avoidance patterns...
  56. pmc Prenatal and postnatal tobacco exposure and behavioral problems in 10-year-old children: results from the GINI-plus prospective birth cohort study
    Simon Rückinger
    Ludwig Maximilians University Munich, Institute of Social Pediatrics and Adolescent Medicine, Division of Epidemiology, Munich, Germany
    Environ Health Perspect 118:150-4. 2010
    ..Prenatal and postnatal tobacco exposure have been reported to be associated with behavioral problems. However, the magnitude of the association with tobacco exposure at specific periods of exposure is unclear...
  57. ncbi request reprint Health risks of early swimming pool attendance
    Yvonne Schoefer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, 85764 Neuherberg, Germany
    Int J Hyg Environ Health 211:367-73. 2008
    ..In terms of developing atopic diseases there is no verifiable detrimental effect of early swimming...
  58. ncbi request reprint Social factors, allergen, endotoxin, and dust mass in mattress
    C M Chen
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Indoor Air 17:384-93. 2007
    ..The observed negative association between cat allergen loads and concentrations in mattress and family SES in non-cat owners' homes indicated that community is an important source of cat allergen exposure...
  59. ncbi request reprint Weight gain in two adult cohorts in East and West Germany reunification
    K Wimmer
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Cent Eur J Public Health 11:202-8. 2003
    ..If different lifestyle factors after German division contribute to these differences, one might speculate that trends of obesity and overweight in the East and West after German reunification in 1990 would be similar...
  60. ncbi request reprint Early antibiotic treatment and later asthma
    M Wjst
    Institut fur Epidemiologie, GSF Forschungszentrum für Umwelt und Gesundheit, Ingolstadter Landstrasse 1, D 85764 Neuherberg Munich, Germany
    Eur J Med Res 6:263-71. 2001
    ..The high dose effect, the time dependency of the administration and the effect by non-pulmonary indications raises the possibility that early antibiotic treatment could itself be related to later asthma...
  61. ncbi request reprint Predictors of group 5 grass-pollen allergens in settled house dust: comparison between pollination and nonpollination seasons
    B Fahlbusch
    Friedrich-Schiller-University, Institute of Clinical Immunology, Jena, GSF - National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Allergy 56:1081-6. 2001
    ..The removal of dust by frequent cleaning reduces the indoor exposure to grass allergens. Such information is essential to train patients in allergen avoidance...
  62. pmc Influence of FADS polymorphisms on tracking of serum glycerophospholipid fatty acid concentrations and percentage composition in children
    Claudia Glaser
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    PLoS ONE 6:e21933. 2011
    ..Tracking of fatty acid (FA) contribution to plasma or serum lipids over time was shown in children and adults. However, the potential role of FADS gene variants has not been investigated...
  63. ncbi request reprint Long-term exposure to ambient air pollution and cardiopulmonary mortality in women
    Ulrike Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, D 85764 Neuherberg, Germany
    Epidemiology 17:545-51. 2006
    ..We assessed whether long-term exposure to air pollution originating from motorized traffic and industrial sources is associated with total and cause-specific mortality in a cohort of women living in North Rhine-Westphalia, Germany...
  64. pmc Long-term exposure to traffic-related air pollution and insulin resistance in children: results from the GINIplus and LISAplus birth cohorts
    E Thiering
    German Research Center for Environmental Health, Neuherberg, Germany
    Diabetologia 56:1696-704. 2013
    ..We aimed to assess the association between traffic-related air pollution and insulin resistance in children...
  65. ncbi request reprint Effect of hydrolysed formula feeding on taste preferences at 10 years. Data from the German Infant Nutritional Intervention Program Plus Study
    Stefanie Sausenthaler
    Helmholtz Zentrum Munchen German Research Center for Environmental Health, Institute of Epidemiology, Germany
    Clin Nutr 29:304-6. 2010
    ..Therefore, the aim of present study was to investigate whether feeding with different kinds of infant formula is associated with the acceptance of infant formula at 10 years of age...
  66. doi request reprint Atopic diseases, allergic sensitization, and exposure to traffic-related air pollution in children
    Verena Morgenstern
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, D 85764 Neuherberg, Germany
    Am J Respir Crit Care Med 177:1331-7. 2008
    ..In vitro studies, animal experiments, and human exposure studies have shown how ambient air pollution increases the risk of atopic diseases. However, results derived from observational studies are inconsistent...
  67. doi request reprint Growth velocity during infancy and onset of asthma in school-aged children
    C Flexeder
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Neuherberg, Germany
    Allergy 67:257-64. 2012
    ..This study examines the association between peak height and weight velocities during the first 2 years of life and onset of asthma and wheeze up to 10 years of age...
  68. ncbi request reprint Parental education and children's respiratory and allergic symptoms in the Pollution and the Young (PATY) study
    U Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Eur Respir J 27:95-107. 2006
    ..However, differences remained after adjusting for these variables. Children's health was associated with parental education. The association could not fully be explained by established risk factors...
  69. doi request reprint Prospective association between food sensitization and food allergy: results of the LISA birth cohort study
    E Schnabel
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Clin Exp Allergy 40:450-7. 2010
    ..Food allergy is common, especially in childhood, where 6-8% of children are affected. Identification of early and efficient markers for later development of food allergy is very important...
  70. ncbi request reprint Vertical and horizontal variability of volatile organic compounds in homes in Eastern Germany
    P Schneider
    GSF Research Center for Environment and Health, Institute of Epidemiology, Munich, Germany
    J Expo Anal Environ Epidemiol 9:282-92. 1999
    ..The indoor BTEX air concentrations were significantly higher than the outdoor concentrations (except benzene). Significant differences in BTEX indoor concentrations between OLD and NEW buildings could not be detected (except toluene)...
  71. ncbi request reprint Vaccination against Haemophilus influenzae type b and atopy in east German schoolchildren
    B Laubereau
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Eur J Med Res 7:387-92. 2002
    ..In this paper we investigated the association of Haemophilus influenzae type b (Hib)-vaccination and atopic diseases and allergic sensitisation in children in Eastern Germany...
  72. ncbi request reprint The distribution in specific IgE and the prevalence of allergic symptoms in 25-64-years old inhabitants of an eastern and a western German city--results from Augsburg and Erfurt
    B Filipiak
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Eur J Epidemiol 17:77-84. 2001
    ..The purpose of this study was to replicate these findings using data from Augsburg, a city from the southern part of West Germany. Furthermore the study population in this analysis was extended to higher age groups...
  73. ncbi request reprint Sources and concentrations of indoor nitrogen dioxide in Hamburg (west Germany) and Erfurt (east Germany)
    J Cyrys
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Sci Total Environ 250:51-62. 2000
    ..This variable caused a similar increase in the indoor NO2 levels in each city (43% in Erfurt and 47% in Hamburg). However, outdoor sources of NO2 (motor vehicle traffic) contributed more to indoor NO2 levels in Hamburg than in Erfurt...
  74. ncbi request reprint Elemental composition and sources of fine and ultrafine ambient particles in Erfurt, Germany
    J Cyrys
    GSF, National Research Center for Environment and Health, Institute of Epidemiology, Geb 56, O 85764, Neuherberg, Germany
    Sci Total Environ 305:143-56. 2003
    ..Sulfur could be a tracer for coal combustion, however, it was not correlated with any of the quoted elements. Highly correlated elements V and Ni have similar enrichment factors and are considered as tracers for oil combustion...
  75. ncbi request reprint Trends and predictors of overweight and obesity in East German children
    C Frye
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Int J Obes Relat Metab Disord 27:963-9. 2003
    ..Therefore, we analyzed trends in overweight and obesity in East German school children...
  76. ncbi request reprint Gas cooking, respiratory health and white blood cell counts in children
    B Hölscher
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Int J Hyg Environ Health 203:29-37. 2000
    ..91-2.10). The strongest effect estimates for chronic inflammation were found for those children likely to have been exposed at higher levels, that is when stoves had no fans, in smaller homes, and for children spending more time indoors...
  77. ncbi request reprint Factors affecting lead and cadmium levels in house dust in industrial areas of eastern Germany
    I Meyer
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Sci Total Environ 234:25-36. 1999
    ....
  78. ncbi request reprint PM25 measurements in ambient aerosol: comparison between Harvard impactor (HI) and the tapered element oscillating microbalance (TEOM) system
    J Cyrys
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Sci Total Environ 278:191-7. 2001
    ..10 x HI - 0.668. Because the measured levels of ammonium nitrate were very low in Erfurt, we concluded that other compounds like semi-volatile organics were responsible for the loss of particulate material at 50 degrees C...
  79. ncbi request reprint Urban background particulate matter and allergic sensitization in adults of ECRHS II
    Getahun Bero Bedada
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, 85764, Neuherberg, Germany
    Int J Hyg Environ Health 210:691-700. 2007
    ..The aim of this study was to evaluate whether regional urban air pollution may partly explain the large variation in the prevalence of allergic sensitization across cities of the European Community Respiratory Health Survey (ECRHS) II...
  80. ncbi request reprint Inverse social gradient of secondary immune response parameters in children
    G Bolte
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Rev Environ Health 14:135-43. 1999
    ..The aim of our study was to assess the relation between social class, immune parameters, and the prevalence of respiratory infections in children...
  81. ncbi request reprint Trends in food intake in adults from the city of Erfurt before and after the German reunification
    G Winkler
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Ann Nutr Metab 41:283-90. 1997
    ..180 g; 209 vs. 174 g and 62 vs. 53 g. Surprisingly similar changes in eating habits were observed with men and women. The majority of changes could be explained by the improved variety in food supply after the reunification...
  82. ncbi request reprint The effect of low-level blood lead on hematologic parameters in children
    B Jacob
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Ingolstadter Landstrasse 1, Neuherberg, D 85758, Germany
    Environ Res 82:150-9. 2000
    ..The reasons for our observation, especially the gender difference, are still uncertain. In conclusion the morphology and function of erythrocytes might be sensitive parameters of low dose lead toxicity...
  83. pmc Association of lung function with declining ambient air pollution
    Christian Frye
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut fur Epidemiologie, Neuherberg, Germany
    Environ Health Perspect 111:383-7. 2003
    ..9% for a decrement of 100 micro g/m(3) SO(2) (p = 0.029). Effects on FEV(1) were smaller and not statistically significant. Our study indicates that a reduction of air pollution in a short time period may improve children's lung function...
  84. doi request reprint Timing of solid food introduction in relation to eczema, asthma, allergic rhinitis, and food and inhalant sensitization at the age of 6 years: results from the prospective birth cohort study LISA
    Anne Zutavern
    GSF National Research Center for Environment and Health, Institute of Epidemiology, 85764 Neuherberg, Germany
    Pediatrics 121:e44-52. 2008
    ..This study investigates whether a delayed introduction of solids (past 4 or 6 months) is protective against the development of eczema, asthma, allergic rhinitis, and food or inhalant sensitization at the age of 6 years...
  85. pmc Impact of ambient air pollution on the differential white blood cell count in patients with chronic pulmonary disease
    Irene Brüske
    Institute of Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environment and Health, Neuherberg, Germany
    Inhal Toxicol 22:245-52. 2010
    ..The increase of particulate and gaseous air pollution was associated with multiple changes in the differential white blood cell count in patients with chronic pulmonary diseases...
  86. pmc Source apportionment of ambient fine particle size distribution using positive matrix factorization in Erfurt, Germany
    Wei Yue
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
    Sci Total Environ 398:133-44. 2008
    ....
  87. ncbi request reprint Seasonal and diurnal variation of PM2.5 apparent particle density in urban air in Augsburg, Germany
    Mike Pitz
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, 85764 Neuherberg, Germany
    Environ Sci Technol 42:5087-93. 2008
    ..rho2.5 has the potential to serve as a crude tracer for chemical composition and atmospheric processing and might play an important role when considering the associations between health effects and ambient particles...
  88. pmc Regional differences in prediction models of lung function in Germany
    Eva Schnabel
    Helmholtz Zentrum Munchen, Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Respir Res 11:40. 2010
    ..The aim of this analysis was to determine whether lung function determinants differ between subpopulations within Germany and whether prediction equations developed for one subpopulation are also adequate for another subpopulation...
  89. ncbi request reprint Risk factors for lung cancer among nonsmoking women
    Michaela Kreuzer
    BfS Federal Office for Radiation Protection, Institute of Radiation Hygiene, Ingolstadter Landstrasse 1, 85764 Neuherberg, Germany
    Int J Cancer 100:706-13. 2002
    ..5; CI:0.25-0.82) and cheese (OR=0.3, CI:0.21-0.55). ETS at work, occupational hazards and previous pneumonia may be risk factors for lung cancer in nonsmoking women, while a diet rich in fresh vegetables and cheese seems to be protective...
  90. ncbi request reprint Longitudinal study on cat allergen exposure and the development of allergy in young children
    Chih Mei Chen
    GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    J Allergy Clin Immunol 119:1148-55. 2007
    ..The influence of cat allergen exposure in early childhood on the development of sensitization and allergic diseases is complex. Little is known about the natural course of the sensitization development within individuals...
  91. ncbi request reprint Indoor and outdoor air concentrations of BTEX and NO2: correlation of repeated measurements
    Rebekka Topp
    GSF National Research Center for Environment Health, Institute of Epidemiology, 85764 Neuherberg, Germany
    J Environ Monit 6:807-12. 2004
    ....
  92. pmc Traffic-related atmospheric pollutants levels during pregnancy and offspring's term birth weight: a study relying on a land-use regression exposure model
    Remy Slama
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Environ Health Perspect 115:1283-92. 2007
    ..Some studies have suggested that particulate matter (PM) levels during pregnancy may be associated with birth weight. Road traffic is a major source of fine PM (PM with aero-dynamic diameter < 2.5 microm; PM(2.5))...
  93. pmc Indoor exposure to molds and allergic sensitization
    Beate Jacob
    GSF Institute of Epidemiology, Munich, Germany
    Environ Health Perspect 110:647-53. 2002
    ..These effects were strongest in the group of children who had lived in the same home since birth...
  94. ncbi request reprint Association of carotenoids, tocopherols and vitamin C in plasma with allergic rhinitis and allergic sensitisation in adults
    Iris Kompauer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Public Health Nutr 9:472-9. 2006
    ....
  95. ncbi request reprint Seasonal variability of endotoxin in ambient fine particulate matter
    Cara L Carty
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, D 85758 Neuherberg, Germany
    J Environ Monit 5:953-8. 2003
    ..Temperature effects and seasonal variation of endotoxin should be considered in future studies of outdoor endotoxin...
  96. ncbi request reprint Solid food introduction in relation to eczema: results from a four-year prospective birth cohort study
    Birgit Filipiak
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    J Pediatr 151:352-8. 2007
    ..To assess the association between the introduction of solid foods in the first 12 months and the occurrence of eczema during the first 4 years of life in a prospective study of newborns...
  97. ncbi request reprint TLR4 gene variants modify endotoxin effects on asthma
    Monika Werner
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Germany
    J Allergy Clin Immunol 112:323-30. 2003
    ..Environmental exposure to endotoxin might have a crucial role in immune maturation and development of asthma...
  98. doi request reprint The role of cats and dogs in asthma and allergy--a systematic review
    Chih Mei Chen
    Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Int J Hyg Environ Health 213:1-31. 2010
    ....
  99. pmc Gender differences in lung cancer risk by smoking: a multicentre case-control study in Germany and Italy
    M Kreuzer
    GSF Institute of Epidemiology, Neuherberg, Germany
    Br J Cancer 82:227-33. 2000
    ..We conclude that for comparable exposure to tobacco smoke, the risk of lung cancer is comparable in women and men...
  100. ncbi request reprint Allergic sensitisation and allergic rhinitis are associated with n-3 polyunsaturated fatty acids in the diet and in red blood cell membranes
    S Hoff
    Unit of Human Nutrition and Cancer Prevention, Technical University of Munich, Munich, Germany
    Eur J Clin Nutr 59:1071-80. 2005
    ..Due to inconsistent results based on dietary intake data, unsaturated fatty acids in red blood cell (RBC) membranes and diet were used to investigate their association with allergic sensitisation and allergic rhinitis...
  101. ncbi request reprint Food and fatty acid intake and atopic disease in adults
    M A Trak-Fellermeier
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Neuherberg, Postfach 11 29, D 85758 Oberschleissheim, Germany
    Eur Respir J 23:575-82. 2004
    ..Dietary factors were mostly not related with prevalence rates of bronchial hyperresponsiveness and atopic eczema either in males or in females...