M Groll

Summary

Country: Germany

Publications

  1. ncbi A gated channel into the proteasome core particle
    M Groll
    Max Planck Institut fur Biochemie, D 82152 Martinsried, Germany
    Nat Struct Biol 7:1062-7. 2000
  2. ncbi Crystal structure of heat shock locus V (HslV) from Escherichia coli
    M Bochtler
    Max Planck Institut fur Biochemie, Am Klopferspitz 18a, D 82152 Martinsried, Germany
    Proc Natl Acad Sci U S A 94:6070-4. 1997
  3. ncbi The proteasome
    M Bochtler
    Max Planck Institut fur Biochemie, Martinsried Planegg, Germany
    Annu Rev Biophys Biomol Struct 28:295-317. 1999
  4. ncbi Crystal structure of the 20 S proteasome:TMC-95A complex: a non-covalent proteasome inhibitor
    M Groll
    Max Planck Institut fur Biochemie, Martinsried, D 82152, Germany
    J Mol Biol 311:543-8. 2001
  5. ncbi The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study
    M Groll
    Max Planck Institut fur Biochemie, D 82152 Martinsried, Germany
    Proc Natl Acad Sci U S A 96:10976-83. 1999
  6. ncbi Structure of 20S proteasome from yeast at 2.4 A resolution
    M Groll
    Max Planck Institut fur Biochemie, Martinsreid, Germany
    Nature 386:463-71. 1997

Collaborators

Detail Information

Publications6

  1. ncbi A gated channel into the proteasome core particle
    M Groll
    Max Planck Institut fur Biochemie, D 82152 Martinsried, Germany
    Nat Struct Biol 7:1062-7. 2000
    ..Inhibition by the alpha-subunit tails is relieved upon binding of the regulatory particle to the CP to form the proteasome holoenzyme...
  2. ncbi Crystal structure of heat shock locus V (HslV) from Escherichia coli
    M Bochtler
    Max Planck Institut fur Biochemie, Am Klopferspitz 18a, D 82152 Martinsried, Germany
    Proc Natl Acad Sci U S A 94:6070-4. 1997
    ..A tripeptide aldehyde inhibitor, acetyl-Leu-Leu-norleucinal, binds to the N-terminal threonine residue of HslV, probably as a hemiacetal, relating HslV also functionally to the proteasomes of archaea and eukaryotes...
  3. ncbi The proteasome
    M Bochtler
    Max Planck Institut fur Biochemie, Martinsried Planegg, Germany
    Annu Rev Biophys Biomol Struct 28:295-317. 1999
    ..A first step toward a mechanistic understanding of proteasome activation and regulation has been made with the elucidation of the X-ray structure of the alternative, mammalian proteasome activator PA28...
  4. ncbi Crystal structure of the 20 S proteasome:TMC-95A complex: a non-covalent proteasome inhibitor
    M Groll
    Max Planck Institut fur Biochemie, Martinsried, D 82152, Germany
    J Mol Biol 311:543-8. 2001
    ..This will form the basis for the development of synthetic selective proteasome inhibitors as promising candidates for anti-tumoral or anti-inflammatory drugs...
  5. ncbi The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study
    M Groll
    Max Planck Institut fur Biochemie, D 82152 Martinsried, Germany
    Proc Natl Acad Sci U S A 96:10976-83. 1999
    ....
  6. ncbi Structure of 20S proteasome from yeast at 2.4 A resolution
    M Groll
    Max Planck Institut fur Biochemie, Martinsreid, Germany
    Nature 386:463-71. 1997
    ....