Sabine Gröbner

Summary

Country: Germany

Publications

  1. doi request reprint Characterization of an Enterococcus faecium small-colony variant isolated from blood culture
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, University of Tubingen, Germany
    Int J Med Microbiol 302:40-4. 2012
  2. ncbi request reprint Severe diarrhoea caused by Aeromonas veronii biovar sobria in a patient with metastasised GIST
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, University of Tubingen, Germany
    Pol J Microbiol 56:277-9. 2007
  3. doi request reprint Lysozyme activates Enterococcus faecium to induce necrotic cell death in macrophages
    Sabine Gröbner
    Interfaculty Institute of Microbiology and Infection Medicine, University of Tubingen, Elfriede Aulhorn Str 6, 72076 Tubingen, Germany
    Cell Mol Life Sci 67:3331-44. 2010
  4. ncbi request reprint Monoclonal outbreak of catheter-related bacteraemia by Ralstonia mannitolilytica on two haemato-oncology wards
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Elfriede Aulhorn Str 6, D 72076 Tubingen, Germany
    J Infect 55:539-44. 2007
  5. ncbi request reprint Catalytically active Yersinia outer protein P induces cleavage of RIP and caspase-8 at the level of the DISC independently of death receptors in dendritic cells
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, University of Tubingen, Elfriede Aulhorn Str, 6, 72076, Tuebingen, Germany
    Apoptosis 12:1813-25. 2007
  6. pmc Absence of Toll-like receptor 4 signaling results in delayed Yersinia enterocolitica YopP-induced cell death of dendritic cells
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Elfriede Aulhorn Str 6, D 72076 Tubingen, Germany
    Infect Immun 75:512-7. 2007
  7. ncbi request reprint Yersinia YopP-induced apoptotic cell death in murine dendritic cells is partially independent from action of caspases and exhibits necrosis-like features
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Elfriede Aulhorn Str 6, D 72076, Tubingen, Germany
    Apoptosis 11:1959-68. 2006
  8. doi request reprint Emergence of carbapenem-non-susceptible extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates at the university hospital of Tübingen, Germany
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Elfriede Aulhorn Str 6, D 72076 Tubingen, Germany
    J Med Microbiol 58:912-22. 2009
  9. doi request reprint Differential roles of Yersinia outer protein P-mediated inhibition of nuclear factor-kappa B in the induction of cell death in dendritic cells and macrophages
    Irena Adkins
    Institute of Medical Microbiology and Hygiene, University of Tubingen, Elfriede Aulhorn Strabe 6, D 72076 Tubingen, Germany
    J Med Microbiol 57:139-44. 2008
  10. doi request reprint Y. enterocolitica inhibits antigen degradation in dendritic cells
    Irena Adkins
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Elfriede Aulhorn Strasse 6, Tubingen, Germany
    Microbes Infect 10:798-806. 2008

Collaborators

Detail Information

Publications14

  1. doi request reprint Characterization of an Enterococcus faecium small-colony variant isolated from blood culture
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, University of Tubingen, Germany
    Int J Med Microbiol 302:40-4. 2012
    ....
  2. ncbi request reprint Severe diarrhoea caused by Aeromonas veronii biovar sobria in a patient with metastasised GIST
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, University of Tubingen, Germany
    Pol J Microbiol 56:277-9. 2007
    ..The case points out the severe and long course of the infection, the diagnostic dilemma, and the prompt recovery after antibiotic treatment...
  3. doi request reprint Lysozyme activates Enterococcus faecium to induce necrotic cell death in macrophages
    Sabine Gröbner
    Interfaculty Institute of Microbiology and Infection Medicine, University of Tubingen, Elfriede Aulhorn Str 6, 72076 Tubingen, Germany
    Cell Mol Life Sci 67:3331-44. 2010
    ..Altogether, our results show that enterococci, under specific conditions such as exposure to lysozyme, induce necrotic cell death in macrophages, which might contribute to disseminated infections by these facultative pathogenic bacteria...
  4. ncbi request reprint Monoclonal outbreak of catheter-related bacteraemia by Ralstonia mannitolilytica on two haemato-oncology wards
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Elfriede Aulhorn Str 6, D 72076 Tubingen, Germany
    J Infect 55:539-44. 2007
    ..mannitolilytica was cultivated from blood samples of all patients suggesting an outbreak...
  5. ncbi request reprint Catalytically active Yersinia outer protein P induces cleavage of RIP and caspase-8 at the level of the DISC independently of death receptors in dendritic cells
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, University of Tubingen, Elfriede Aulhorn Str, 6, 72076, Tuebingen, Germany
    Apoptosis 12:1813-25. 2007
    ..Altogether our findings indicate that Yersinia-induced DC death is independent of death domain containing receptors, but mediated by RIP and caspase-8 at the level of DISC...
  6. pmc Absence of Toll-like receptor 4 signaling results in delayed Yersinia enterocolitica YopP-induced cell death of dendritic cells
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Elfriede Aulhorn Str 6, D 72076 Tubingen, Germany
    Infect Immun 75:512-7. 2007
    ..Later (>4 h), DC die independent of TLR4 signaling. In TLR4-deficient DC caspase 8 cleavage is delayed, indicating that TLR4 signaling accelerates caspase 8 activation, leading to DC death...
  7. ncbi request reprint Yersinia YopP-induced apoptotic cell death in murine dendritic cells is partially independent from action of caspases and exhibits necrosis-like features
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Elfriede Aulhorn Str 6, D 72076, Tubingen, Germany
    Apoptosis 11:1959-68. 2006
    ..However, it has to be resolved if necrosis-like DC death occurs independently from apoptotic events or as an apoptotic epiphenomenon...
  8. doi request reprint Emergence of carbapenem-non-susceptible extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates at the university hospital of Tübingen, Germany
    Sabine Gröbner
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Elfriede Aulhorn Str 6, D 72076 Tubingen, Germany
    J Med Microbiol 58:912-22. 2009
    ..Therefore, a systematic exploration of intestinal colonization with ESBL isolates should be reconsidered, at least for haemato-oncological departments from where four of the five carbapenem-non-susceptible ESBL isolates originated...
  9. doi request reprint Differential roles of Yersinia outer protein P-mediated inhibition of nuclear factor-kappa B in the induction of cell death in dendritic cells and macrophages
    Irena Adkins
    Institute of Medical Microbiology and Hygiene, University of Tubingen, Elfriede Aulhorn Strabe 6, D 72076 Tubingen, Germany
    J Med Microbiol 57:139-44. 2008
    ..The differences between DC and macrophages in the mechanisms of cell death induction by YopP presented herein might be crucial for the function of these antigen-presenting cells...
  10. doi request reprint Y. enterocolitica inhibits antigen degradation in dendritic cells
    Irena Adkins
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Elfriede Aulhorn Strasse 6, Tubingen, Germany
    Microbes Infect 10:798-806. 2008
    ..difficile. However, the contribution of other pYV-encoded factors cannot be excluded...
  11. pmc Yersinia enterocolitica induces apoptosis and inhibits surface molecule expression and cytokine production in murine dendritic cells
    Stella E Erfurth
    Institute of Medical Microbiology and Hygiene, University of Tubingen, Elfriede Aulhorn Strasse 6, D 72076 Tubingen, Germany
    Infect Immun 72:7045-54. 2004
    ..Together, these data demonstrate that Y. enterocolitica targets functions of murine DC that are required for T-cell activation. This might contribute to evasion of adaptive immune responses by Y. enterocolitica...
  12. ncbi request reprint Yersinia outer proteins E, H, P, and T differentially target the cytoskeleton and inhibit phagocytic capacity of dendritic cells
    Irena Adkins
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Tubingen, Germany
    Int J Med Microbiol 297:235-44. 2007
    ....
  13. doi request reprint Lysozyme facilitates adherence of Enterococcus faecium to host cells and induction of necrotic cell death
    Steffen Höring
    Interfaculty Institute of Microbiology and Infection Medicine, University of Tubingen, Elfriede Aulhorn Str 6, 72076 Tubingen, Germany
    Microbes Infect 14:554-62. 2012
    ..Moreover, bacterial extracellular hydrogen peroxide might contribute to necrosis induction, since the rate of propidium iodide-positive HeLa and J774A.1 cells was lowered after infection with a ROS-deficient E. faecium mutant...
  14. doi request reprint In vitro activity of tigecycline and molecular characterization of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates from a university hospital in south-western Germany
    Matthias Wienke
    Institute of Medical Microbiology and Hygiene, Eberhard Karls University of Tubingen, Tubingen, Germany
    Chemotherapy 58:241-8. 2012
    ..Extended-spectrum β-lactamase (ESBL)-producing organisms are spreading worldwide in hospital and community settings...