Research Topics
| Gabriele GilleSummaryCountry: Germany Publications
| Collaborators
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Detail Information
Publications
Iron-dependent functions of mitochondria--relation to neurodegenerationGabriele Gille
Klinik und Poliklinik fur Neurologie, TU Dresden, Fetscherstr 74, 01307, Dresden, Germany
J Neural Transm 118:349-59. 2011..Resulting accumulation of iron into mitochondria might lead to oxidative stress damaging iron-sulphur cluster-containing proteins...
9-Methyl-beta-carboline up-regulates the appearance of differentiated dopaminergic neurones in primary mesencephalic cultureJuliane Hamann
Department of Neurology, Technical University of Dresden, Fetscherstr 74, 01307 Dresden, Germany
Neurochem Int 52:688-700. 2008....
The exceptional properties of 9-methyl-beta-carboline: stimulation, protection and regeneration of dopaminergic neurons coupled with anti-inflammatory effectsWitold Polanski
Department of Neurology, Technical University of Dresden, Dresden, Germany
J Neurochem 113:1659-75. 2010..Further investigations are currently under way...
Stimulation, protection and regeneration of dopaminergic neurons by 9-methyl-β-carboline: a new anti-Parkinson drug?Witold Polanski
Department of Neurology, Technical University of Dresden, Fetscherstr 74, 01307 Dresden, Germany
Expert Rev Neurother 11:845-60. 2011..This article summarizes our current knowledge of 9-methyl-carboline and discusses its potential role as a new drug for the treatment of PD...
Neurotoxic mechanisms of 2,9-dimethyl-beta-carbolinium ion in primary dopaminergic cultureJuliane Hamann
Department of Neurology, Technical University of Dresden, Dresden, Germany
J Neurochem 98:1185-99. 2006..These data underline the preferential susceptibility of dopaminergic neurones to 2,9-Me(2)NH(+) as a potent, oxidative stress generating neurotoxin...
Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in miceFrancisco Pan-Montojo
Institute of Anatomy, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
PLoS ONE 5:e8762. 2010..It provides new insight into how environmental factors could trigger PD and suggests a transsynaptic mechanism by which PD might spread throughout the central nervous system...
