M O Weickert

Summary

Affiliation: German Institute of Human Nutrition
Country: Germany

Publications

  1. ncbi request reprint [Significance of biomarkers for metabolic syndrome during weight reduction]
    H Rochlitz
    Deutsches Institut für Ernährungsforschung Potsdam, Nuthetal und Abteilung für Endokrinologie, Diabetes und Ernährungsmedizin, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Deutschland
    Dtsch Med Wochenschr 130:1061-6. 2005
  2. ncbi request reprint [Preventing type 2 diabetes: what does dietary fiber achieve?]
    M O Weickert
    Deutsches Institut für Ernährungsfoschung, Potsdam Rehbruecke
    MMW Fortschr Med 147:28-30. 2005
  3. ncbi request reprint Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety
    Martin O Weickert
    Department of Endocrinology, Diabetes and Nutrition, Charite University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    Br J Nutr 96:795-8. 2006
  4. ncbi request reprint Impact of cereal fibre on glucose-regulating factors
    M O Weickert
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    Diabetologia 48:2343-53. 2005
  5. ncbi request reprint Signalling mechanisms linking hepatic glucose and lipid metabolism
    M O Weickert
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
    Diabetologia 49:1732-41. 2006
  6. ncbi request reprint Cereal fiber improves whole-body insulin sensitivity in overweight and obese women
    Martin O Weickert
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal 14558, Germany
    Diabetes Care 29:775-80. 2006
  7. ncbi request reprint Arabinoxylan fibre consumption improved glucose metabolism, but did not affect serum adipokines in subjects with impaired glucose tolerance
    A L Garcia
    Dietary Fibre and the Metabolic Syndrome Group, German Institute of Human Nutrition, Potsdam Rehbruecke, Nuthetal, Germany
    Horm Metab Res 38:761-6. 2006
  8. ncbi request reprint Arabinoxylan consumption decreases postprandial serum glucose, serum insulin and plasma total ghrelin response in subjects with impaired glucose tolerance
    A L Garcia
    Dietary Fibre and the Metabolic Syndrome Group, German Institute of Human Nutrition, Potsdam Rehbruecke, Nuthetal, Germany
    Eur J Clin Nutr 61:334-41. 2007
  9. doi request reprint Intravenous lipid and heparin infusion-induced elevation in free fatty acids and triglycerides modifies circulating androgen levels in women: a randomized, controlled trial
    K Mai
    Department of Endocrinology, Diabetes, and Nutrition, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, 12200 Berlin, Germany
    J Clin Endocrinol Metab 93:3900-6. 2008
  10. doi request reprint Effects of euglycemic hyperinsulinemia and lipid infusion on circulating cholecystokinin
    M O Weickert
    Department of Endocrinology, Diabetes, and Nutrition, Charite University Medicine, Campus Benjamin Franklin, Free University of Berlin, Berlin, Germany
    J Clin Endocrinol Metab 93:2328-33. 2008

Collaborators

Detail Information

Publications27

  1. ncbi request reprint [Significance of biomarkers for metabolic syndrome during weight reduction]
    H Rochlitz
    Deutsches Institut für Ernährungsforschung Potsdam, Nuthetal und Abteilung für Endokrinologie, Diabetes und Ernährungsmedizin, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Deutschland
    Dtsch Med Wochenschr 130:1061-6. 2005
    ..We aimed to analyse the changes of parameters of the metabolic syndrome and to investigate which markers are useful in the prediction of a successful weight loss. Preliminary data of an ongoing study are presented...
  2. ncbi request reprint [Preventing type 2 diabetes: what does dietary fiber achieve?]
    M O Weickert
    Deutsches Institut für Ernährungsfoschung, Potsdam Rehbruecke
    MMW Fortschr Med 147:28-30. 2005
    ....
  3. ncbi request reprint Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety
    Martin O Weickert
    Department of Endocrinology, Diabetes and Nutrition, Charite University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    Br J Nutr 96:795-8. 2006
    ..Postprandial hunger scores were unaffected by the different test meals (P>0.15). Thus, oat- and wheat-fibre consumption result in different postprandial responses of PYY and ghrelin, but interestingly do not differ in satiety effects...
  4. ncbi request reprint Impact of cereal fibre on glucose-regulating factors
    M O Weickert
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    Diabetologia 48:2343-53. 2005
    ..We investigated whether a short-term dietary intervention with purified insoluble fibres influences acute and delayed responses of glucose, insulin, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1...
  5. ncbi request reprint Signalling mechanisms linking hepatic glucose and lipid metabolism
    M O Weickert
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
    Diabetologia 49:1732-41. 2006
    ..Understanding the molecular network that links hepatic lipid accumulation and impaired glucose metabolism may provide targets for dietary or pharmacological interventions...
  6. ncbi request reprint Cereal fiber improves whole-body insulin sensitivity in overweight and obese women
    Martin O Weickert
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal 14558, Germany
    Diabetes Care 29:775-80. 2006
    ..The pathogenic background of this phenomenon is unknown. Based on recent findings, we hypothesized that intake of purified insoluble oat fiber may improve whole-body insulin sensitivity...
  7. ncbi request reprint Arabinoxylan fibre consumption improved glucose metabolism, but did not affect serum adipokines in subjects with impaired glucose tolerance
    A L Garcia
    Dietary Fibre and the Metabolic Syndrome Group, German Institute of Human Nutrition, Potsdam Rehbruecke, Nuthetal, Germany
    Horm Metab Res 38:761-6. 2006
    ..In conclusion, the consumption of AX in subjects with impaired glucose tolerance improved fasting serum glucose, and triglycerides. However, this beneficial effect was not accompanied by changes in fasting adipokine concentrations...
  8. ncbi request reprint Arabinoxylan consumption decreases postprandial serum glucose, serum insulin and plasma total ghrelin response in subjects with impaired glucose tolerance
    A L Garcia
    Dietary Fibre and the Metabolic Syndrome Group, German Institute of Human Nutrition, Potsdam Rehbruecke, Nuthetal, Germany
    Eur J Clin Nutr 61:334-41. 2007
    ..Therefore, we investigated the postprandial responses to AX consumption of serum glucose, insulin and triglycerides and plasma total and acylated ghrelin in subjects with impaired glucose tolerance (IGT)...
  9. doi request reprint Intravenous lipid and heparin infusion-induced elevation in free fatty acids and triglycerides modifies circulating androgen levels in women: a randomized, controlled trial
    K Mai
    Department of Endocrinology, Diabetes, and Nutrition, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, 12200 Berlin, Germany
    J Clin Endocrinol Metab 93:3900-6. 2008
    ..Despite the high prevalence of PCOS and the considerable clinical impact, the precise interplay between metabolism and hyperandrogenemia is not entirely clear...
  10. doi request reprint Effects of euglycemic hyperinsulinemia and lipid infusion on circulating cholecystokinin
    M O Weickert
    Department of Endocrinology, Diabetes, and Nutrition, Charite University Medicine, Campus Benjamin Franklin, Free University of Berlin, Berlin, Germany
    J Clin Endocrinol Metab 93:2328-33. 2008
    ..Postprandial CCK responses are significantly blunted in type 2 diabetic patients by unknown mechanisms. We hypothesized that hyperinsulinemia and lipid infusion influence circulating levels of biologically active CCK...
  11. ncbi request reprint Euglycemic hyperinsulinemia differentially modulates circulating total and acylated-ghrelin in humans
    M O Weickert
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    J Endocrinol Invest 31:119-24. 2008
    ..Factors other than changes in insulin and lipid concentrations are likely to contribute to the previously reported post-prandial reduction of circulating acyl-ghrelin...
  12. doi request reprint T3/rT3-ratio is associated with insulin resistance independent of TSH
    S Ruhla
    Department of Endocrinology, Diabetes and Nutrition, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
    Horm Metab Res 43:130-4. 2011
    ..Here we show that the T3/rT3-ratio, which is supposed to reflect the tissue thyroid hormone metabolism, is significantly increased in insulin resistant subjects. This further supports a link between thyroid function and IR...
  13. doi request reprint Levothyroxine medication is associated with adiposity independent of TSH
    S Ruhla
    Department of Endocrinology, Diabetes and Nutrition, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
    Exp Clin Endocrinol Diabetes 120:351-4. 2012
    ..We therefore investigated the association between levothyroxine medication and BMI in a large cross-sectional study group...
  14. ncbi request reprint Serum resistin increases in a postprandial state during liquid meal challenge test in healthy human subjects
    S Gruendel
    Dietary Fibre and the Metabolic Syndrome Research Group, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    J Endocrinol Invest 29:RC27-30. 2006
    ..Additional studies are needed to elucidate normal 24-h daytime profiles in humans and differential response of serum resistin to macronutrient composition of meals...
  15. doi request reprint Improved insulin sensitivity, preserved beta cell function and improved whole-body glucose metabolism after low-dose growth hormone replacement therapy in adults with severe growth hormone deficiency: a pilot study
    A M Arafat
    Department of Endocrinology, Diabetes and Nutrition, Charite University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany
    Diabetologia 53:1304-13. 2010
    ..We postulated that long-term low-dose growth hormone replacement, restoring IGF-1 to the low-normal range, might beneficially affect glucose metabolism...
  16. doi request reprint The impact of insulin-independent, glucagon-induced suppression of total ghrelin on satiety in obesity and type 1 diabetes mellitus
    A M Arafat
    MD, Department of Endocrinology, Diabetes, and Nutrition, Charite University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany
    J Clin Endocrinol Metab 98:4133-42. 2013
    ..We further aimed to identify a possible mechanistic impact of changes in endogenous insulin...
  17. doi request reprint Impairment of fat oxidation under high- vs. low-glycemic index diet occurs before the development of an obese phenotype
    F Isken
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    Am J Physiol Endocrinol Metab 298:E287-95. 2010
    ..Early onset and significantly impaired fatty acid oxidation preceded these changes, thereby indicating a potentially causal involvement...
  18. doi request reprint Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice
    F Isken
    Department of Clinical Nutrition, German Institute of Human Nutrition, Potsdam Rehbruecke, Germany
    Diabetologia 52:2159-68. 2009
    ..Different effects of these diets could be age-dependent, as well as mediated, in part, by carbohydrate-induced stimulation of glucose-dependent insulinotrophic polypeptide (GIP) signalling...
  19. ncbi request reprint Glucagon suppression of ghrelin secretion is exerted at hypothalamus-pituitary level
    A M Arafat
    Department of Endocrinology, Diabetes, and Nutrition, Charite University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    J Clin Endocrinol Metab 91:3528-33. 2006
    ..The mechanisms underlying the well-known glucagon-induced satiety effect are unclear. Recently, we showed that glucagon induces a remarkable decrease in the orexigenic hormone ghrelin that might be responsible for this effect...
  20. ncbi request reprint Free fatty acids increase androgen precursors in vivo
    K Mai
    Dept of Endocrinology, Diabetes and Nutrition, Charite University Medicine Berlin, Campus Benjamin Franklin, 12200 Berlin, Germany
    J Clin Endocrinol Metab 91:1501-7. 2006
    ..However, other metabolic factors such as free fatty acids (FFAs) may also contribute to androgen excess...
  21. doi request reprint Annual change in insulin sensitivity
    F Isken
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbrucke, Nuthetal, Germany
    Horm Metab Res 43:720-2. 2011
    ..5% of the variation. IS showed a significant moderate annual periodicity, which may affect the interpretation of studies reporting small changes in IS...
  22. ncbi request reprint Predicting impaired glucose metabolism in women with polycystic ovary syndrome by decision tree modelling
    M Mohlig
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, 14558 Nuthetal, Germany
    Diabetologia 49:2572-9. 2006
    ..Screening for impaired glucose metabolism (IGM) with an OGTT has been recommended, but this is relatively time-consuming and inconvenient. Thus, a strategy that could minimise the need for an OGTT would be beneficial...
  23. ncbi request reprint Arabinoxylan-enriched meal increases serum ghrelin levels in healthy humans
    M Mohlig
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    Horm Metab Res 37:303-8. 2005
    ..This effect is therefore unlikely to be mediated by insulin, but the underlying mechanism remains to be elucidated...
  24. ncbi request reprint Increase in serum resistin during weight loss in overweight subjects is related to lipid metabolism
    C Koebnick
    Dietary Fiber and the Metabolic Syndrome Research Group, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    Int J Obes (Lond) 30:1097-103. 2006
    ..Human resistin has been stated to influence preadipocyte cell numbers and to stimulate adipocyte triglyceride lipolysis in vivo and in vitro. However, its role in human obesity remains unclear...
  25. doi request reprint Elevated hepatic chemerin mRNA expression in human non-alcoholic fatty liver disease
    S Döcke
    Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
    Eur J Endocrinol 169:547-57. 2013
    ..On the other hand, hepatic chemerin and chemokine-like receptor 1 (CMKLR1) mRNA expression has not yet been studied in an extensively characterized patient collective...
  26. ncbi request reprint Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36
    P T Pfluger
    Department of Psychiatry, University of Cincinnati, Office E 217, Genome Research Institute, 2170 East Galbraith Road, Cincinnati, Ohio 45237, USA
    J Clin Endocrinol Metab 92:583-8. 2007
    ..Although the pharmacological value of PYY is controversial, further study of the secretion of the precursor PYY(1-36) and the pharmacologically active PYY(3-36) is indicated to determine the potential role in energy balance regulation...
  27. ncbi request reprint Gender differences in the metabolic syndrome and their role for cardiovascular disease
    V Regitz-Zagrosek
    Center for Gender in Medicine and Cardiovascular Disease in Women, Charite and Deutsches Herzzentrum Berlin, Germany
    Clin Res Cardiol 95:136-47. 2006
    ....