Research Topics
| T WaterboerSummaryAffiliation: German Cancer Research Center Country: Germany Publications
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Detail Information
Publications
Measures of cutaneous human papillomavirus infection in normal tissues as biomarkers of HPV in corresponding nonmelanoma skin cancersDana E Rollison
Division of Cancer Prevention and Control, Moffitt Cancer Center, Tampa, FL, USA
Int J Cancer 123:2337-42. 2008..Based on the current case series, the combinations of antibodies+eyebrow hairs or antibodies+eyebrow hairs+Dacron swabs are the optimal, minimally invasive markers of cutaneous HPV infection for use in epidemiologic studies...
Multiplex human papillomavirus serology based on in situ-purified glutathione s-transferase fusion proteinsTim Waterboer
Infection and Cancer Program, German Cancer Research Center DKFZ, Heidelberg, Germany
Clin Chem 51:1845-53. 2005..Using bead-based technology, we have developed an assay platform that allows the simultaneous detection of antibodies against up to 100 in situ affinity-purified recombinant HPV proteins...
Suppression of non-specific binding in serological Luminex assaysTim Waterboer
Infection and Cancer Program, German Cancer Research Center DKFZ, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany
J Immunol Methods 309:200-4. 2006....
Antibody responses to 26 skin human papillomavirus types in the Netherlands, Italy and AustraliaTim Waterboer
Department of Genome Modifications and Carcinogenesis, Infections and Cancer Program, German Cancer Research Center, Heidelberg, Germany
J Gen Virol 90:1986-98. 2009....
Serological association of beta and gamma human papillomaviruses with squamous cell carcinoma of the skinT Waterboer
Infection and Cancer Program, German Cancer Research Center, DKFZ, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Br J Dermatol 159:457-9. 2008..The potential association of cutaneous HPV types from the genera alpha, gamma, mu and nu with skin SCC has not been thoroughly analysed so far...
Bead-based multiplex genotyping of 58 cutaneous human papillomavirus typesK M Michael
Department of Genome Modifications and Carcinogenesis, Infection and Cancer Program, German Cancer Research Center, 69120 Heidelberg, Germany
J Clin Microbiol 49:3560-7. 2011..7 HPV types with nested FAP-PCR). In conclusion, McPG is a powerful tool for genotyping multiple cutaneous HPVs in a high-throughput format and is thus suitable for large-scale epidemiological studies...
Homogeneous amplification of genital human alpha papillomaviruses by PCR using novel broad-spectrum GP5+ and GP6+ primersMarkus Schmitt
German Cancer Research Center, Infection and Cancer, Im Neuenheimer Feld 280, Heidelberg D 69120, Germany
J Clin Microbiol 46:1050-9. 2008..BSGP5+/6+-MPG, therefore, is suitable for epidemiologic and also diagnostic applications...
Cutaneous human papillomavirus infection, the EVER2 gene and incidence of squamous cell carcinoma: a case-control studyAnita S Patel
Department of Environmental Health, Harvard School of Public Health, Boston, MA
Int J Cancer 122:2377-9. 2008..7, 95% CI 1.1-2.7]. These data provide evidence for a role of genetic variation in the EVER2 gene in beta-HPV infection and risk of SCC, shedding light on the link between HPVs and skin cancers...
Seroprevalence of 34 human papillomavirus types in the German general populationKristina M Michael
Infection and Cancer Program, German Cancer Research Center DKFZ, Heidelberg, Germany
PLoS Pathog 4:e1000091. 2008....
Seroreactivity to cutaneous human papillomaviruses among patients with nonmelanoma skin cancer or benign skin lesionsKristin Andersson
Department of Medical Microbiology, Malmo University Hospital, Lund University, UMAS, Malmo, Sweden
Cancer Epidemiol Biomarkers Prev 17:189-95. 2008..01). In conclusion, additional studies are required to clarify the biological meaning of seropositivity as a marker of cutaneous HPV infection and skin disease...
Presence of DNA of human papillomavirus 16 but no other types in tumor-free tonsillar tissueRenwei Chen
Department of Virology, Haartman Institute, Haartmaninkatu 3, P O Box 21, 00014 University of Helsinki, Helsinki, Finland
J Clin Microbiol 43:1408-10. 2005..3% (13 of 206) in tonsillitis or hypertrophic tonsillar tissues and 0.6% (1 of 174) in exfoliated cells from normal tonsils. HPV-16 was the only type detected in tonsillar tissues, but it did not appear to lead to L1 antibody production...
Human papillomavirus-16 is the predominant type etiologically involved in penile squamous cell carcinomaDaniëlle A M Heideman
Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
J Clin Oncol 25:4550-6. 2007..Therefore, we performed molecular and serologic analyses for a broad spectrum of HPV types on a large series of 83 penile SCCs, and we compared serological findings to those of age-matched male controls (N = 83)...
Serologic response to oncogenic human papillomavirus types in male and female university students in Busan, South KoreaGary M Clifford
IARC, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
Cancer Epidemiol Biomarkers Prev 16:1874-9. 2007..In contrast, HPV seropositivity among men was not associated with sexual behavior or the presence of HPV DNA. Seroprevalence correlates with genital HPV exposure in young women, but its meaning in young men is unclear...
A prospective pilot study of antibodies against human papillomaviruses and cutaneous squamous cell carcinoma nested in the Oxford component of the European Prospective Investigation into Cancer and NutritionDelphine Casabonne
Cancer Epidemiology Unit, Richard Doll Building, University of Oxford, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7LF, United Kingdom
Int J Cancer 121:1862-8. 2007..Further and larger prospective studies are needed to clarify the role of HPV in the aetiology of cutaneous SCC...
Human papillomavirus infection among 100 oesophageal cancer cases in the People's Republic of ChinaMin Dai
Int J Cancer 121:1396-8. 2007
Human papillomavirus infection and incidence of squamous cell and basal cell carcinomas of the skinMargaret R Karagas
Department of Community and Family Medicine, Center for Environmental Health Sciences, Dartmouth Medical School, Lebanon, NH 03756, USA
J Natl Cancer Inst 98:389-95. 2006....
Bead-based multiplex genotyping of human papillomavirusesMarkus Schmitt
Research Program Infection and Cancer, German Cancer Research Center DKFZ, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany
J Clin Microbiol 44:504-12. 2006..922) but also indicated a higher sensitivity of MPG. In conclusion, MPG appears to be highly suitable for large-scale epidemiological studies and vaccination trials as well as for routine diagnostic purposes...
Absence of SV40 antibodies or DNA fragments in prediagnostic mesothelioma serum samplesKristina Kjaerheim
The Cancer Registry of Norway, Oslo, Norway
Int J Cancer 120:2459-65. 2007..No viral DNA was found in the sera. No significant association between SV40 antibody response in prediagnostic sera and risk of mesothelioma was seen...
Characterization of humoral immune responses against p16, p53, HPV16 E6 and HPV16 E7 in patients with HPV-associated cancersMiriam Reuschenbach
Department of Applied Tumor Biology, University of Heidelberg, Heidelberg, Germany
Int J Cancer 123:2626-31. 2008..9-11.1). In conclusion, despite the strong expression of p16 and the observed induction of cellular immune responses, antibody reactivity against p16 was observed only at very low levels independent of the disease background...
Reactivity pattern of 92 monoclonal antibodies with 15 human papillomavirus typesRaeda Z Rizk
Department of Genome Modifications and Cancer, Infection and Cancer Program, German Cancer Research Center DKFZ, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany
J Gen Virol 89:117-29. 2008..Distantly related mucosal and skin alpha papillomaviruses share some conformational epitopes and the phylogenetic L1-based species definition may not define a serological unit since no species-specific epitope was found...
