Andreas Trumpp

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. doi request reprint Defined conditions for the isolation and expansion of Basal prostate progenitor cells of mouse and human origin
    Thomas Hofner
    Heidelberg Institute for Stem Cell Technology and Experimental Medicine HI STEM gGmbH, 69120 Heidelberg, Germany
    Stem Cell Reports 4:503-18. 2015
  2. pmc Transcriptome-wide Profiling and Posttranscriptional Analysis of Hematopoietic Stem/Progenitor Cell Differentiation toward Myeloid Commitment
    Daniel Klimmeck
    Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum DKFZ, 69120 Heidelberg, Germany Heidelberg Institute for Stem Cell Technology and Experimental Medicine HI STEM gGmbH, 69120 Heidelberg, Germany European Molecular Biology Laboratory EMBL, Genome Biology Unit, 69120 Heidelberg, Germany German Cancer Consortium DKTK
    Stem Cell Reports 3:858-75. 2014
  3. pmc Serial enumeration of circulating tumor cells predicts treatment response and prognosis in metastatic breast cancer: a prospective study in 393 patients
    Markus Wallwiener
    National Center for Tumor Diseases, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany
    BMC Cancer 14:512. 2014
  4. pmc The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in
    Armin Ehninger
    Division of Stem Cells and Cancer, German Cancer Research Center, D 69120 Heidelberg, Germany
    J Exp Med 208:421-8. 2011
  5. pmc The evolving concept of cancer and metastasis stem cells
    Irène Baccelli
    Heidelberg Institute for Stem Cell Technology and Experimental Medicine, D 69120 Heidelberg, Germany
    J Cell Biol 198:281-93. 2012
  6. pmc c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland
    Tina Stoelzle
    Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
    BMC Biol 7:63. 2009
  7. doi request reprint Awakening dormant haematopoietic stem cells
    Andreas Trumpp
    Heidelberg Institute for Stem Cell Technology and Experimental Medicine, German Cancer Research Center, Germany
    Nat Rev Immunol 10:201-9. 2010
  8. doi request reprint Targeting leukemic stem cells by breaking their dormancy
    Marieke Alida Gertruda Essers
    HI STEM Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Division of Stem Cells and Cancer, German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, Heidelberg, Germany
    Mol Oncol 4:443-50. 2010
  9. pmc Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization
    Melania Tesio
    Deutsches Krebsforschungszentrum DKFZ, D 69120 Heidelberg, Germany
    J Exp Med 210:2337-49. 2013
  10. pmc Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B
    Larissa S Carnevalli
    Heidelberg Institute for Stem Cell Technology and Experimental Medicine HI STEM gGmbH, D 69120 Heidelberg, Germany
    J Exp Med 211:769-79. 2014

Collaborators

  • Jeroen Krijgsveld
  • Marieke Alida Gertruda Essers
  • Jenny Hansson
  • Irène Baccelli
  • Daniel Klimmeck
  • Melania Tesio
  • Thomas Hofner
  • Markus Wallwiener
  • Larissa S Carnevalli
  • Nina Cabezas-Wallscheid
  • Armin Ehninger
  • Tina Stoelzle
  • Martin R Sprick
  • Wilko Weichert
  • Steve Wagner
  • Anja Schillert
  • Sascha Pahernik
  • Anna Jauch
  • Elisa Noll
  • Christian Eisen
  • Stephan M Goeppinger
  • Vanessa Vogel
  • Corinna Klein
  • Teresa Rigo-Watermeier
  • Brigitte Schoell
  • Miriam Erlacher
  • Andreas Schneeweiss
  • Christof Sohn
  • Christoph Domschke
  • Alejandro Reyes
  • Lars Jöckel
  • Apostolos Polykratis
  • Elisa Laurenti
  • Barbara Burwinkel
  • Sabine Riethdorf
  • Juliane Nees
  • Stefanie Sujer
  • Frederik Marme
  • Lisa von Paleske
  • Roberta Scognamiglio
  • Simon Renders
  • Caroline Modugno
  • Jörg Heil
  • Kohei Masuda
  • Sarah Schott
  • Wolfgang Huber
  • Andrea Kück
  • Birgitt Schönfisch
  • Martin Ronald Sprick
  • Dharanija Madhavan
  • Andreas Daniel Hartkopf
  • Susann Rahmig
  • Manolis Pasparakis
  • Klaus Pantel
  • Gabriela M Oser
  • Hong Wu
  • Joachim R Gothert
  • Scott C Kogan
  • William Blanco-Bose
  • Sergey Y Vakhrushev
  • Simon Raffel
  • Nancy E Hynes
  • Patrick Schwarb

Detail Information

Publications13

  1. doi request reprint Defined conditions for the isolation and expansion of Basal prostate progenitor cells of mouse and human origin
    Thomas Hofner
    Heidelberg Institute for Stem Cell Technology and Experimental Medicine HI STEM gGmbH, 69120 Heidelberg, Germany
    Stem Cell Reports 4:503-18. 2015
    ..This novel method will facilitate the molecular, genomic, and functional characterization of normal and pathologic prostate glands of mouse and human origin. ..
  2. pmc Transcriptome-wide Profiling and Posttranscriptional Analysis of Hematopoietic Stem/Progenitor Cell Differentiation toward Myeloid Commitment
    Daniel Klimmeck
    Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum DKFZ, 69120 Heidelberg, Germany Heidelberg Institute for Stem Cell Technology and Experimental Medicine HI STEM gGmbH, 69120 Heidelberg, Germany European Molecular Biology Laboratory EMBL, Genome Biology Unit, 69120 Heidelberg, Germany German Cancer Consortium DKTK
    Stem Cell Reports 3:858-75. 2014
    ..This in-depth molecular analysis outlines the enormous complexity of expressed coding and noncoding RNAs and posttranscriptional regulation during the early differentiation steps of hematopoietic stem cells toward the myeloid lineage. ..
  3. pmc Serial enumeration of circulating tumor cells predicts treatment response and prognosis in metastatic breast cancer: a prospective study in 393 patients
    Markus Wallwiener
    National Center for Tumor Diseases, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany
    BMC Cancer 14:512. 2014
    ....
  4. pmc The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in
    Armin Ehninger
    Division of Stem Cells and Cancer, German Cancer Research Center, D 69120 Heidelberg, Germany
    J Exp Med 208:421-8. 2011
    ....
  5. pmc The evolving concept of cancer and metastasis stem cells
    Irène Baccelli
    Heidelberg Institute for Stem Cell Technology and Experimental Medicine, D 69120 Heidelberg, Germany
    J Cell Biol 198:281-93. 2012
    ..The CSC concept has therefore evolved to better model the complex and highly dynamic processes of tumorigenesis, tumor relapse, and metastasis...
  6. pmc c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland
    Tina Stoelzle
    Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
    BMC Biol 7:63. 2009
    ..Here we investigated functions of c-Myc during mouse mammary gland development using a conditional knockout approach...
  7. doi request reprint Awakening dormant haematopoietic stem cells
    Andreas Trumpp
    Heidelberg Institute for Stem Cell Technology and Experimental Medicine, German Cancer Research Center, Germany
    Nat Rev Immunol 10:201-9. 2010
    ..Thus, we propose that two-step strategies could target resistant leukaemic stem cells by priming tumours with activators of dormancy followed by chemotherapy or targeted therapies...
  8. doi request reprint Targeting leukemic stem cells by breaking their dormancy
    Marieke Alida Gertruda Essers
    HI STEM Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Division of Stem Cells and Cancer, German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, Heidelberg, Germany
    Mol Oncol 4:443-50. 2010
    ....
  9. pmc Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization
    Melania Tesio
    Deutsches Krebsforschungszentrum DKFZ, D 69120 Heidelberg, Germany
    J Exp Med 210:2337-49. 2013
    ....
  10. pmc Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B
    Larissa S Carnevalli
    Heidelberg Institute for Stem Cell Technology and Experimental Medicine HI STEM gGmbH, D 69120 Heidelberg, Germany
    J Exp Med 211:769-79. 2014
    ..Blockade of GzmB production may help to improve hematopoiesis in various situations of BM stress. ..
  11. pmc Proteomic cornerstones of hematopoietic stem cell differentiation: distinct signatures of multipotent progenitors and myeloid committed cells
    Daniel Klimmeck
    Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum DKFZ, INF 280, DE 69120 Heidelberg, Germany
    Mol Cell Proteomics 11:286-302. 2012
    ....
  12. doi request reprint Breaking the cell cycle of HSCs by p57 and friends
    Melania Tesio
    Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Cell Stem Cell 9:187-92. 2011
    ..Two new Cell Stem Cell articles in this issue (Matsumoto et al., 2011; Zou et al., 2011) now show that the CDK inhibitor p57 is a crucial brake for cycling HSCs, and links self-renewal activity to cell cycle quiescence...
  13. doi request reprint IFNalpha activates dormant haematopoietic stem cells in vivo
    Marieke A G Essers
    Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum DKFZ, DKFZ ZMBH Alliance, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Nature 458:904-8. 2009
    ..These data may help to clarify the so far unexplained clinical effects of IFNalpha on leukaemic cells, and raise the possibility for new applications of type I interferons to target cancer stem cells...