Dietmar H Pieper

Summary

Affiliation: German Research Centre for Biotechnology
Country: Germany

Publications

  1. pmc Monitoring key reactions in degradation of chloroaromatics by in situ (1)H nuclear magnetic resonance: solution structures of metabolites formed from cis-dienelactone
    Dietmar H Pieper
    Division of Microbiology, GBF German Research Center for Biotechnology, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    J Bacteriol 184:1466-70. 2002
  2. ncbi request reprint Engineering bacteria for bioremediation
    D H Pieper
    Department of Environmental Biotechnology, Gesellschaft für Biotechnologische Forschung mbH GBF, Braunschweig, D 38124, Germany
    Curr Opin Biotechnol 11:262-70. 2000
  3. ncbi request reprint Aerobic degradation of polychlorinated biphenyls
    Dietmar H Pieper
    Department of Environmental Microbiology, German Research Center for Biotechnology, Mascheroder Weg 1, 38124, Braunschweig, Germany
    Appl Microbiol Biotechnol 67:170-91. 2005
  4. pmc Two angular dioxygenases contribute to the metabolic versatility of dibenzofuran-degrading Rhodococcus sp. strain HA01
    Hamdy A H Aly
    Department of Environmental Microbiology, HZI Helmholtz Centre for Infection Research, Inhoffenstrasse 7, D 38124 Braunschweig, Germany
    Appl Environ Microbiol 74:3812-22. 2008
  5. pmc Assessment of toluene/biphenyl dioxygenase gene diversity in benzene-polluted soils: links between benzene biodegradation and genes similar to those encoding isopropylbenzene dioxygenases
    Robert Witzig
    Department of Environmental Microbiology, GBF German Research Centre for Biotechnology, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    Appl Environ Microbiol 72:3504-14. 2006
  6. pmc Characterization of a gene cluster involved in 4-chlorocatechol degradation by Pseudomonas reinekei MT1
    Beatriz Cámara
    Department of Microbial Pathogenesis, HZI Helmholtz Centre for Infection Research, Braunschweig, Germany
    J Bacteriol 191:4905-15. 2009
  7. ncbi request reprint Difference in kinetic behaviour of catechol 2,3-dioxygenase variants from a polluted environment
    Howard Junca
    Department of Environmental Microbiology, GBF German Research Centre for Biotechnology, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    Microbiology 150:4181-7. 2004
  8. pmc New bacterial pathway for 4- and 5-chlorosalicylate degradation via 4-chlorocatechol and maleylacetate in Pseudomonas sp. strain MT1
    Patricia Nikodem
    Department of Environmental Microbiology, GBF German Research Center for Biotechnology, D 38124 Braunschweig, Germany
    J Bacteriol 185:6790-800. 2003
  9. pmc Degradation of 2,3-dihydroxybenzoate by a novel meta-cleavage pathway
    Macarena Marín
    Microbial Interactions and Processes Research Group, HZI Helmholtz Centre for Infection Research, Braunschweig, Germany
    J Bacteriol 194:3851-60. 2012
  10. ncbi request reprint Functional gene diversity analysis in BTEX contaminated soils by means of PCR-SSCP DNA fingerprinting: comparative diversity assessment against bacterial isolates and PCR-DNA clone libraries
    Howard Junca
    Department of Environmental Microbiology, GBF German Research Centre for Biotechnology, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    Environ Microbiol 6:95-110. 2004

Collaborators

  • Matthias Platzer
  • Beatriz Cámara
  • Peter N Golyshin
  • Stefan Taudien
  • Marina C Pils
  • Andrew P A Oxley
  • Andre Bleich
  • Michael Seeger
  • Michael Schlömann
  • W Reineke
  • Balbina Nogales
  • Wolf Rainer Abraham
  • Christof von Eiff
  • K Becker
  • Howard Junca
  • Ramiro Vilchez-Vargas
  • Melissa L Wos-Oxley
  • Victor Wray
  • Amélia Camarinha-Silva
  • Macarena Marín
  • Iris Plumeier
  • Katrin Pollmann
  • Robert Witzig
  • Eberhard Schmidt
  • Bernardo Gonzalez
  • Hamdy A H Aly
  • Melissa Wos-Oxley
  • Ruy Jauregui
  • Danilo Pérez-Pantoja
  • Hans Jürgen Hecht
  • Britta K Scheithauer
  • Barbara Hendrickx
  • Markus Göbel
  • Patricia Nikodem
  • Luisa Barreiros
  • David B McKay
  • Thomas Ledger
  • Nicole Trefault
  • Vanessa Sabrina Kaser
  • Robert Geffers
  • Christian Mandt
  • María Suárez-Diez
  • Monika Kralova
  • Dick B Janssen
  • Ianina Conte
  • Agnes Waliczek
  • Anna Smoczek
  • Hannes Nahrstedt
  • Eva Medina
  • Hans Jürgen Hedrich
  • Lydia M Janus
  • Silke Kahl
  • Raul Donoso
  • Björn Ferslev
  • Helmut Jablonowski
  • Nguyen B Huu
  • Carsten Strompl
  • Thomas Egli
  • Winnie Dejonghe
  • Vladimir Brenner
  • Irene Rüegg
  • Margarete Bucheli-Witschel
  • Jolana Vosahlova
  • Antje Lindner
  • Folkert Faber
  • Maria Brennerova
  • Eva M Top
  • Dirk Springael
  • Margit Mau
  • Leen Bastiaens
  • Oliver H Kranz
  • Stefan R Kaschabek
  • Olga C Nunes
  • Volker Hecht
  • Antonio C Silva Ferreira
  • Matthias Prucha
  • Célia M Manaia
  • Kenneth N Timmis
  • Maria A Reis
  • Stefan Kaschabek
  • Marlene Manzano
  • Sabina Heim
  • Pascale Clément

Detail Information

Publications37

  1. pmc Monitoring key reactions in degradation of chloroaromatics by in situ (1)H nuclear magnetic resonance: solution structures of metabolites formed from cis-dienelactone
    Dietmar H Pieper
    Division of Microbiology, GBF German Research Center for Biotechnology, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    J Bacteriol 184:1466-70. 2002
    ..One-dimensional (1)H NMR in (1)H(2)O could thus be shown to be an excellent noninvasive tool for monitoring enzyme activities and assessing the solution structure of substrates and products...
  2. ncbi request reprint Engineering bacteria for bioremediation
    D H Pieper
    Department of Environmental Biotechnology, Gesellschaft für Biotechnologische Forschung mbH GBF, Braunschweig, D 38124, Germany
    Curr Opin Biotechnol 11:262-70. 2000
    ..With molecular methods allowing the characterization of microbial community structure and activities, the performance of microorganisms under in situ conditions and in concert with the indigenous microflora will become predictable...
  3. ncbi request reprint Aerobic degradation of polychlorinated biphenyls
    Dietmar H Pieper
    Department of Environmental Microbiology, German Research Center for Biotechnology, Mascheroder Weg 1, 38124, Braunschweig, Germany
    Appl Microbiol Biotechnol 67:170-91. 2005
    ..However, further research is necessary to understand the complex interactions between soil/sediment, pollutant, surfactant and microorganisms in different environments...
  4. pmc Two angular dioxygenases contribute to the metabolic versatility of dibenzofuran-degrading Rhodococcus sp. strain HA01
    Hamdy A H Aly
    Department of Environmental Microbiology, HZI Helmholtz Centre for Infection Research, Inhoffenstrasse 7, D 38124 Braunschweig, Germany
    Appl Environ Microbiol 74:3812-22. 2008
    ..strain HA01 constitutes the first described example of a bacterial strain where coexpression of two angular dioxygenases was observed. Such complementary activity allows for the efficient transformation of chlorinated DBFs...
  5. pmc Assessment of toluene/biphenyl dioxygenase gene diversity in benzene-polluted soils: links between benzene biodegradation and genes similar to those encoding isopropylbenzene dioxygenases
    Robert Witzig
    Department of Environmental Microbiology, GBF German Research Centre for Biotechnology, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    Appl Environ Microbiol 72:3504-14. 2006
    ....
  6. pmc Characterization of a gene cluster involved in 4-chlorocatechol degradation by Pseudomonas reinekei MT1
    Beatriz Cámara
    Department of Microbial Pathogenesis, HZI Helmholtz Centre for Infection Research, Braunschweig, Germany
    J Bacteriol 191:4905-15. 2009
    ....
  7. ncbi request reprint Difference in kinetic behaviour of catechol 2,3-dioxygenase variants from a polluted environment
    Howard Junca
    Department of Environmental Microbiology, GBF German Research Centre for Biotechnology, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    Microbiology 150:4181-7. 2004
    ....
  8. pmc New bacterial pathway for 4- and 5-chlorosalicylate degradation via 4-chlorocatechol and maleylacetate in Pseudomonas sp. strain MT1
    Patricia Nikodem
    Department of Environmental Microbiology, GBF German Research Center for Biotechnology, D 38124 Braunschweig, Germany
    J Bacteriol 185:6790-800. 2003
    ....
  9. pmc Degradation of 2,3-dihydroxybenzoate by a novel meta-cleavage pathway
    Macarena Marín
    Microbial Interactions and Processes Research Group, HZI Helmholtz Centre for Infection Research, Braunschweig, Germany
    J Bacteriol 194:3851-60. 2012
    ..This is the first report describing a gene cluster encoding enzymes for the degradation of 2,3-dihydroxybenzoate...
  10. ncbi request reprint Functional gene diversity analysis in BTEX contaminated soils by means of PCR-SSCP DNA fingerprinting: comparative diversity assessment against bacterial isolates and PCR-DNA clone libraries
    Howard Junca
    Department of Environmental Microbiology, GBF German Research Centre for Biotechnology, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    Environ Microbiol 6:95-110. 2004
    ....
  11. pmc Modified 3-oxoadipate pathway for the biodegradation of methylaromatics in Pseudomonas reinekei MT1
    Macarena Marín
    Department of Microbial Pathogenesis, Helmholtz Zentrum für Infektionsforschung, Braunschweig, Germany
    J Bacteriol 192:1543-52. 2010
    ..Accumulation of methylsuccinate by an mmlK deletion mutant indicates that the encoded acetyl-CoA hydrolase/transferase is crucial for channeling methylsuccinate into the central metabolism...
  12. pmc Substrate specificity and expression of three 2,3-dihydroxybiphenyl 1,2-dioxygenases from Rhodococcus globerulus strain P6
    David B McKay
    Department of Environmental Microbiology, GBF German Research Center for Biotechnology, D 38124 Braunschweig, Germany
    J Bacteriol 185:2944-51. 2003
    ..globerulus P6...
  13. ncbi request reprint Molecular detection and diversity of novel diterpenoid dioxygenase DitA1 genes from proteobacterial strains and soil samples
    Robert Witzig
    Department of Environmental Microbiology, HZI Helmholtz Centre for Infection Research, Inhoffenstrasse 7, D 38124 Braunschweig, Germany
    Environ Microbiol 9:1202-18. 2007
    ..The molecular fingerprints indicated the presence ofa broad, previously unrecognized diversity of diterpenoid dioxygenase genes in soils, and suggest that other bacterial phyla may also harbour the genetic potential for DhA-degradation...
  14. doi request reprint A poke into the diversity and associations within human anterior nare microbial communities
    Melissa L Wos-Oxley
    Microbial Interactions and Processes Research Group, Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    ISME J 4:839-51. 2010
    ..aureus infections...
  15. ncbi request reprint Genomic and mechanistic insights into the biodegradation of organic pollutants
    Dietmar H Pieper
    Division of Microbiology, German Research Centre for Biotechnology, Mascheroder Weg 1, Braunschweig, Germany
    Curr Opin Biotechnol 15:215-24. 2004
    ..Systems biology approaches are still in their infancy, but are becoming increasingly helpful to unravel, predict and quantify metabolic abilities within particular organisms or microbial consortia...
  16. ncbi request reprint Pseudomonas reinekei sp. nov., Pseudomonas moorei sp. nov. and Pseudomonas mohnii sp. nov., novel species capable of degrading chlorosalicylates or isopimaric acid
    Beatriz Cámara
    Division of Microbiology, HZI Helmholtz Zentrum für Infektionsforschung, Inhoffenstrasse 7, 38124 Braunschweig, Germany
    Int J Syst Evol Microbiol 57:923-31. 2007
    ..nov. (type strain MT1(T) =DSM 18361(T)=CCUG 53116(T)), Pseudomonas moorei sp. nov. (type strain RW10(T) =DSM 12647(T)=CCUG 53114(T)) and Pseudomonas mohnii sp. nov. (type strain IpA-2(T) =DSM 18327(T)=CCUG 53115(T)) are proposed...
  17. pmc Chloromethylmuconolactones as critical metabolites in the degradation of chloromethylcatechols: recalcitrance of 2-chlorotoluene
    Katrin Pollmann
    Bereich Mikrobiologie, AG Biodegradation, Gesellschaft fur Biotechnologische Forschung mbH, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    J Bacteriol 187:2332-40. 2005
    ..3-Chloro-5-methylcatechol is transformed to 2-chloro-4-methylmuconolactone...
  18. pmc Metabolism of dichloromethylcatechols as central intermediates in the degradation of dichlorotoluenes by Ralstonia sp. strain PS12
    Katrin Pollmann
    Department of Environmental Microbiology, GBF German Research Center for Biotechnology, D 38124 Braunschweig Chemical Microbiology, Bergische University, Wuppertal, Germany
    J Bacteriol 184:5261-74. 2002
    ..2,5-Dichloro-3-methylmuconolactone was transformed nearly exclusively into 2-chloro-3-methyl-trans-dienelactone...
  19. ncbi request reprint Rational engineering of the regioselectivity of TecA tetrachlorobenzene dioxygenase for the transformation of chlorinated toluenes
    Katrin Pollmann
    Department of Environmental Microbiology, GBF German Research Centre for Biotechnology, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    Microbiology 149:903-13. 2003
    ..As new products, 3,4,6-trichloro-1-methyl-1,2-dihydroxy-1,2-dihydrocyclohexan-3,5-diene, 4,6-dichloro-3-methylcatechol, 3,6-dichloro-4-methylcatechol and 3,4-dichloro-6-methylcatechol were identified...
  20. pmc A gene cluster involved in degradation of substituted salicylates via ortho cleavage in Pseudomonas sp. strain MT1 encodes enzymes specifically adapted for transformation of 4-methylcatechol and 3-methylmuconate
    Beatriz Cámara
    Division of Microbiology, HZI Helmholtz Zentrum für Infektionsforschung, Inhoffenstrasse 7, D 38124 Braunschweig, Germany
    J Bacteriol 189:1664-74. 2007
    ....
  21. doi request reprint Analysis of the microbial gene landscape and transcriptome for aromatic pollutants and alkane degradation using a novel internally calibrated microarray system
    Ramiro Vilchez-Vargas
    Microbial Interactions and Processes Research Group, HZI Helmholtz Centre for Infection Research, Inhoffenstraße 7, D 38124 Braunschweig, Germany
    Environ Microbiol 15:1016-39. 2013
    ....
  22. doi request reprint Characterization of the complex bacterial communities colonizing biliary stents reveals a host-dependent diversity
    Britta K Scheithauer
    Department of Microbial Pathogenesis, Helmholtz Centre for Infection Research, Braunschweig, Germany
    ISME J 3:797-807. 2009
    ..Consideration of the community composition from individual patients will allow tailoring of prophylactic antibiotic treatments and thus will make the management of stent biofilms more effective...
  23. doi request reprint Validating T-RFLP as a sensitive and high-throughput approach to assess bacterial diversity patterns in human anterior nares
    Amélia Camarinha-Silva
    Microbial Interactions and Processes Research Group, Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    FEMS Microbiol Ecol 79:98-108. 2012
    ..So, in the age of post 'omics' and 'deep sequencing', there is still a place for these well-tried and well-tested methods that can offer a rapid, reproducible and economical alternative, whereby also yielding valuable new information...
  24. pmc Importance of different tfd genes for degradation of chloroaromatics by Ralstonia eutropha JMP134
    Iris Plumeier
    Department of Environmental Biotechnology, GBF German Research Center for Biotechnology, D 38124 Braunschweig, Germany
    J Bacteriol 184:4054-64. 2002
    ....
  25. doi request reprint Bacterial metabolism of polychlorinated biphenyls
    Dietmar H Pieper
    Biodegradation Research Group, Division of Microbiology, HZI, Helmholtz Centre for Infection Research, Braunschweig, Germany
    J Mol Microbiol Biotechnol 15:121-38. 2008
    ..Overall, metabolism of biphenyl and PCBs should not be regarded as a simple linear pathway, but as a complex interplay between different catabolic gene modules...
  26. doi request reprint The temporal dynamics of bacterial communities across human anterior nares
    Amélia Camarinha-Silva
    Microbial Interactions and Processes Research Group, Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    Environ Microbiol Rep 4:126-32. 2012
    ....
  27. pmc Comparative evaluation of establishing a human gut microbial community within rodent models
    Melissa Wos-Oxley
    Microbial Interactions and Processes Research Group, Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    Gut Microbes 3:234-49. 2012
    ..Thus, the genetic background of the different recipient rodent systems (that is, rats and mice) strongly influences the nature of the populating human gut microbiota, determining each model's biological suitability...
  28. ncbi request reprint Amplified functional DNA restriction analysis to determine catechol 2,3-dioxygenase gene diversity in soil bacteria
    Howard Junca
    Department of Environmental Microbiology, GBF German Research Centre for Biotechnology, Mascheroder Weg 1, D 38124 Brunswick, Germany
    J Microbiol Methods 55:697-708. 2003
    ..This approach may be useful to differentiate functional genes also for many other gene families...
  29. doi request reprint Metabolic networks, microbial ecology and 'omics' technologies: towards understanding in situ biodegradation processes
    Ramiro Vilchez-Vargas
    Microbial Interactions and Processes Research Group, HZI Helmholtz Centre for Infection Research, Inhoffenstraße 7, D 38124 Braunschweig, Germany
    Environ Microbiol 12:3089-104. 2010
    ..Collectively, this will allow tracking regulation and evolution within microbial communities ultimately aiming to understand the mechanisms taking place in large scale bioremediation treatments for aromatic decontamination...
  30. doi request reprint Degradation of chloroaromatics: structure and catalytic activities of wild-type chlorocatechol 2,3-dioxygenases and modified ones
    Eberhard Schmidt
    Bergische Universitat Wuppertal, Chemische Mikrobiologie, D 42097 Wuppertal, Germany
    Environ Microbiol 15:183-90. 2013
    ..A pronounced increase in activity for 3-chlorocatechol resulted by the change from alanine to valine and from aspartic acid to glycine laying in the outer substrate tunnel at position 211 and 212 respectively...
  31. ncbi request reprint Polychlorinated biphenyl-degrading microbial communities in soils and sediments
    Wolf Rainer Abraham
    Division of Microbiology, Gesellschaft für Biotechnologische Forschung German Research Centre for Biotechnology, Mascheroder Weg 1, 38124, Braunschweig, Germany
    Curr Opin Microbiol 5:246-53. 2002
    ..Here, we provide an overview of the current knowledge of aerobic and anaerobic degradation of PCBs in microbial consortia and in the environment, including novel approaches to determine in situ PCB degradation...
  32. ncbi request reprint Novel insights into the interplay between peripheral reactions encoded by xyl genes and the chlorocatechol pathway encoded by tfd genes for the degradation of chlorobenzoates by Ralstonia eutropha JMP134
    Thomas Ledger
    Laboratorio de Microbiologia, Departamento de Genetica Molecular y Microbiologia, Facultad de Ciencias Biologicas, Pontificia Universidad Catolica de Chile, Casilla 114 D Santiago, Chile
    Microbiology 148:3431-40. 2002
    ..eutropha JMP134, these new properties are strongly influenced by the dosage of the tfd genes, the presence of a chromosomal xylS-like regulatory element and the different contributions of the tfd gene clusters...
  33. ncbi request reprint Microorganisms degrading chlorobenzene via a meta-cleavage pathway harbor highly similar chlorocatechol 2,3-dioxygenase-encoding gene clusters
    Markus Göbel
    Chemische Mikrobiologie, Bergische Universitat Wuppertal, Fachbereich C, Gaubetastrabetae 20, 42097 Wuppertal, Germany
    Arch Microbiol 182:147-56. 2004
    ..The current study suggests that meta-cleavage of 3-chlorocatechol is not an atypical pathway for the degradation of chlorobenzene...
  34. ncbi request reprint The copy number of the catabolic plasmid pJP4 affects growth of Ralstonia eutropha JMP134 (pJP4) on 3-chlorobenzoate
    Nicole Trefault
    Laboratorio de Microbiologia, Departamento de Genetica Molecular y Microbiologia, Facultad de Ciencias Biologicas, Pontificia Universidad Catolica de Chile, Casilla 114 D, Santiago, Chile
    FEMS Microbiol Lett 212:95-100. 2002
    ..Therefore, several copies of pJP4 per chromosome are required for full expression of the tfd-encoded growth abilities in the wild-type R. eutropha strain...
  35. doi request reprint trans-Dienelactone hydrolase from Pseudomonas reinekei MT1, a novel zinc-dependent hydrolase
    Beatriz Cámara
    Department of Microbial Pathogenesis, HZI Helmholtz Centre for Infection Research, Inhoffenstr 7, 38124 Braunschweig, Germany
    Biochem Biophys Res Commun 376:423-8. 2008
    ..It is the first member of COG1878 and PF04199 for which a direct physiological function has been reported...
  36. ncbi request reprint A novel pathway for mineralization of the thiocarbamate herbicide molinate by a defined bacterial mixed culture
    Luisa Barreiros
    Departamento de Engenharia Quimica, Faculdade de Engenharia, Universidade do Porto, Porto, Portugal
    Environ Microbiol 5:944-53. 2003
    ..In this way, interactions among defined mixed culture members involve metabolic and detoxifying association...
  37. ncbi request reprint Alternative primer sets for PCR detection of genotypes involved in bacterial aerobic BTEX degradation: distribution of the genes in BTEX degrading isolates and in subsurface soils of a BTEX contaminated industrial site
    Barbara Hendrickx
    Environmental and Process Technology Vito, Flemish Institute for Technological Research, B 2400 Mol, Belgium
    J Microbiol Methods 64:250-65. 2006
    ..They indicate that bacteria carrying specific pathways and primarily carrying tmoA/xylM/xylE1 genotypes, are being selected upon BTEX contamination...