Research Topics
| Klaus J PetzkeSummaryAffiliation: German Institute of Human Nutrition Country: Germany Publications
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Detail Information
Publications
Carbon and nitrogen stable isotopic composition of hair protein and amino acids can be used as biomarkers for animal-derived dietary protein intake in humansKlaus J Petzke
German Institute of Human Nutrition Potsdam Rehbruecke DIfE, D 14558 Nuthetal, Germany
J Nutr 135:1515-20. 2005....
Nitrogen isotopic composition in hair protein is different in liver cirrhotic patientsKlaus J Petzke
German Institute of Human Nutrition Potsdam Rehbruecke DIfE, Arthur Scheunert Allee 114 116, D 14558 Nuthetal, Germany
Rapid Commun Mass Spectrom 20:2973-8. 2006....
Choice of dietary protein of vegetarians and omnivores is reflected in their hair protein 13C and 15N abundanceKlaus J Petzke
German Institute of Human Nutrition Potsdam Rehbruecke DIfE, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
Rapid Commun Mass Spectrom 19:1392-400. 2005..In conclusion, hair 13C and 15N values both reflected the extent of animal protein consumption. Bulk isotopic abundance of hair can be tested for future use in the validation of dietary assessment methods...
Short-term, increasing dietary protein and fat moderately affect energy expenditure, substrate oxidation and uncoupling protein gene expression in ratsKlaus J Petzke
Groups of Stable Isotopes and of Energy Metabolism, German Institute of Human Nutrition in Potsdam Rehbrücke DIfE, D 14558 Nuthetal, Germany
J Nutr Biochem 18:400-7. 2007..A function of UCPs in energy balance and dissipating food energy was suggested. Future experiments are focused on the regulation of UCP gene expression by dietary protein, which could be important for body-weight management...
Long-term dietary high protein intake up-regulates tissue specific gene expression of uncoupling proteins 1 and 2 in ratsKlaus J Petzke
German Institute of Human Nutrition, Potsdam Rehbrücke DIfE, 14558 Nuthetal, Germany
Eur J Nutr 44:414-21. 2005..We hypothesized that the dietary protein level can affect gene expression of uncoupling protein (UCP) homologues which is suggested to be involved in thermogenesis, substrate oxidation, and energy expenditure...
cis-9,trans-11 and trans-10,cis-12 CLA affect lipid metabolism differently in primary white and brown adipocytes of Djungarian hamstersCornelia C Metges
German Institute of Human Nutrition, 14558 Bergholz Rehbrucke, Germany
Lipids 38:1133-42. 2003..The opposite effects of c9,t11-CLA and t10,c12-CLA are evident in both WAT and BAT cultures; however, brown adipocytes seem to be more susceptible to CLA treatment...
Advances in natural stable isotope ratio analysis of human hair to determine nutritional and metabolic statusKlaus J Petzke
German Institute of Human Nutrition Potsdam Rehbruecke DIfE, Nuthetal, Germany
Curr Opin Clin Nutr Metab Care 13:532-40. 2010..In particular, we examine whether hair isotopic compositions can be used as unbiased biomarkers to provide information about nutritional status, metabolism, and diseases...
Body weight and energy homeostasis was not affected in C57BL/6 mice fed high whey protein or leucine-supplemented low-fat dietsAnne Noatsch
German Institute of Human Nutrition in Potsdam Rehbruecke DIfE, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
Eur J Nutr 50:479-88. 2011..Leucine is suggested to act as nutrient signal of high-protein diets regulating pathways associated with an alleviation of metabolic syndrome parameters. However, the subject remains controversial...
Hair protein and amino acid 13C and 15N abundances take more than 4 weeks to clearly prove influences of animal protein intake in young women with a habitual daily protein consumption of more than 1 g per kg body weightKlaus J Petzke
German Institute of Human Nutrition Potsdam Rehbruecke DIfE, Arthur Scheunert Allee 114 116, D 14558 Nuthetal, Germany
Rapid Commun Mass Spectrom 23:2411-20. 2009..The reliability of SIA as biomarkers of protein intake still have to be tested in longer lasting intervention studies in humans. The results may have implications in the assessment for possible benefits and risks of protein consumption...
Practical recommendations for the reduction of memory effects in compound-specific 15N/14N-ratio analysis of enriched amino acids by gas chromatography/combustion/isotope ratio mass spectrometryKlaus J Petzke
German Institute of Human Nutrition in Potsdam Rehbruecke DIfE, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
Rapid Commun Mass Spectrom 26:195-204. 2012..Results need to be interpreted with caution if complex physiological samples contain (15)N-enriched amino acids beyond 500‰ ?(15)N (~0.18 APE)...
Reactions of chlorogenic acid and quercetin with a soy protein isolate--influence on the in vivo food protein quality in ratsSascha Rohn
Department of Food Analysis, Institute of Food Technology and Food Chemistry, Technical University of Berlin, TIB 4 3 1, Gustav Meyer Allee 25, D 13355 Berlin, Germany
Mol Nutr Food Res 50:696-704. 2006..As a result, true nitrogen digestibility, BV, and net protein utilization were adversely affected. Protein digestibility corrected amino acid score was decreased for lysine, tryptophan, and sulfur containing amino acids...
Chlorogenic acid moderately decreases the quality of whey proteins in ratsKlaus J Petzke
German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE, University of Potsdam, D-14558 Nuthetal, A. Scheunert Allee 114-116, Germany
J Agric Food Chem 53:3714-20. 2005..Derivatization of beta-LG with CA does not seem to lead to an additional deficiency in a specific indispensable AA in growing rats fed with 10% protein...
Contribution of intestinal microbial lysine to lysine homeostasis is reduced in minipigs fed a wheat gluten-based dietGunda Backes
Unit Protein Metabolism, German Institute of Human Nutrition, , Germany
Am J Clin Nutr 76:1317-25. 2002..CONCLUSION: Minipigs fed the WG diet did not adapt by showing an enhanced absorption of microbial lysine to the extrasplanchnic tissues, presumably because microbial lysine continues to be used for splanchnic protein synthesis...
Low-abundance plasma and urinary [(15)N]urea enrichments analyzed by gas chromatography/combustion/isotope ratio mass spectrometryCornelia C Metges
Research Unit Nutritional Physiology, Forschungsinstitut für die Biologie landwirtschaftlicher Nutztiere Research Institute for the Biology of Farm Animals, D 18196 Dummerstorf, Germany
J Mass Spectrom 37:489-94. 2002..The different [(15)N]urea enrichments observed after ingestion of [(15)N]-labeled glycine and lysine confirm known differences in the metabolism of these amino acids...
Increased fat-free body mass and no adverse effects on blood lipid concentrations 4 weeks after additional meat consumption in comparison with an exclusion of meat in the diet of young healthy womenKlaus J Petzke
Group of Stable Isotopes and of Energy Metabolism, German Institute of Human Nutrition in Potsdam Rehbruecke DIfE, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
J Nutr Metab 2011:210930. 2011..Conclusions. Additional meat intake can increase FFM without adverse effects on blood lipid concentrations. Long-term studies are required. Urinary excretion of 3-methylhistidine could represent a biomarker for meat protein consumption...
Ileal losses of nitrogen and amino acids in humans and their importance to the assessment of amino acid requirementsClaire Gaudichon
Institut National de la Recherche Agronomique, Unité de Physiologie de la Nutrition et du Comportement Alimentaire, Paris, France
Gastroenterology 123:50-9. 2002..We have investigated amino acid losses at the ileal level in humans after ingestion of a protein meal...
Reduced postprandial energy expenditure and increased exogenous fat oxidation in young woman after ingestion of test meals with a low protein contentKlaus J Petzke
Group of Stable Isotopes and of Energy Metabolism, German Institute of Human Nutrition in Potsdam Rehbruecke DIfE, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
Nutr Metab (Lond) 5:25. 2008..We tested the hypothesis whether low protein content in single meals may induce lower values of energy expenditure (EE) and fat oxidation (FO) as compared to adequate protein content...
Utilization of essential amino acids synthesized in the intestinal microbiota of monogastric mammalsCornelia C Metges
Research Institute for the Biology of Farm Animals (FBN, Research Unit Nutritional Physiology, Wilhelm-Stahl-Allee 2, D-18196 Dummerstorf, Germany
Br J Nutr 94:621-2. 2005
Meal amino acids with varied levels of arginine do not affect postprandial vascular endothelial function in healthy young menFrançois Mariotti
INRA, AgroParisTech, UMR914 Nutrition Physiology and Ingestive Behavior, F 75005 Paris, France
J Nutr 137:1383-9. 2007..Unexpectedly, arginine in physiological amounts may acutely lessen smooth muscle cell reactivity to a high dynamic NO release...
